ES2147788T3 - 3,4-diarilcromanos para el tratamiento de la dermatitis. - Google Patents

3,4-diarilcromanos para el tratamiento de la dermatitis.

Info

Publication number
ES2147788T3
ES2147788T3 ES94911467T ES94911467T ES2147788T3 ES 2147788 T3 ES2147788 T3 ES 2147788T3 ES 94911467 T ES94911467 T ES 94911467T ES 94911467 T ES94911467 T ES 94911467T ES 2147788 T3 ES2147788 T3 ES 2147788T3
Authority
ES
Spain
Prior art keywords
dermatitis
treatment
diarilcromanos
medicaments
diarylchromans
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94911467T
Other languages
English (en)
Inventor
James R Piggott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Application granted granted Critical
Publication of ES2147788T3 publication Critical patent/ES2147788T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

METODOS Y COMPOSICIONES FARMACEUTICAS PARA EL TRATAMIENTO DE DERMATITIS. SE FORMULAN 3,4-DIARILCROMANOS Y SUS SALES FARMACEUTICAMENTE ACEPTABLES EN MEDICAMENTOS, QUE COMPRENDEN MEDICAMENTOS ORALES Y TOPICOS, QUE SE ADMINISTRAN A UN PACIENTE QUE PADECE DE DERMATITIS. LOS METODOS Y LAS COMPOSICIONES SON PARTICULARMENTE UTILES EN EL TRATAMIENTO DE CONDICIONES CARACTERIZADAS POR HIPERPROLIFERACION DE QUERATINOCITOS, TALES COMO LA SORIASIS.
ES94911467T 1993-03-11 1994-03-07 3,4-diarilcromanos para el tratamiento de la dermatitis. Expired - Lifetime ES2147788T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/029,739 US5451603A (en) 1993-03-11 1993-03-11 3,4-diarylchromans for treatment of dermatitis

Publications (1)

Publication Number Publication Date
ES2147788T3 true ES2147788T3 (es) 2000-10-01

Family

ID=21850620

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94911467T Expired - Lifetime ES2147788T3 (es) 1993-03-11 1994-03-07 3,4-diarilcromanos para el tratamiento de la dermatitis.

Country Status (11)

Country Link
US (2) US5451603A (es)
EP (1) EP0688215B1 (es)
JP (1) JPH08506347A (es)
AT (1) ATE193442T1 (es)
CA (1) CA2158036C (es)
DE (1) DE69424777T2 (es)
DK (1) DK0688215T3 (es)
ES (1) ES2147788T3 (es)
GR (1) GR3034186T3 (es)
PT (1) PT688215E (es)
WO (1) WO1994020099A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5416098A (en) * 1993-12-30 1995-05-16 Zymogenetics, Inc. Method for treating dermatitis and related conditions
HUP9702246A3 (en) * 1995-01-20 1999-12-28 Novo Nordisk As Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of degenerative cerebral disorders
US20030083733A1 (en) * 1997-10-10 2003-05-01 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5837313A (en) * 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US6099562A (en) * 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US20020091433A1 (en) * 1995-04-19 2002-07-11 Ni Ding Drug release coated stent
US5624902A (en) * 1995-06-07 1997-04-29 Torrey Pines Institute For Molecular Studies Peptide inhibitors of calmodulin
US5958967A (en) * 1996-10-28 1999-09-28 Novo Nordisk A/S Cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US6117911A (en) * 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
WO1999024032A1 (en) * 1997-11-10 1999-05-20 Novo Nordisk A/S Transdermal delivery of 3,4-diarylchromans
US6613083B2 (en) * 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US7601855B2 (en) 2004-09-21 2009-10-13 Novogen Research Pty Ltd Substituted chroman derivatives, medicaments and use in therapy
US8080675B2 (en) 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
WO2012061413A2 (en) 2010-11-01 2012-05-10 Marshall Edwards, Inc. Isoflavonoid compositions and methods for the treatment of cancer
KR102395543B1 (ko) 2014-02-07 2022-05-09 카지아 테라퓨틱스 리미티드 기능화된 벤조피란 화합물 및 이의 용도
ES2877712T3 (es) 2015-02-02 2021-11-17 Mei Pharma Inc Terapias combinadas para su uso en el tratamiento del cáncer de mama

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3340276A (en) * 1964-04-01 1967-09-05 Ciba Geigy Corp 3, 4-diphenyl-chromans
US3822287A (en) * 1969-04-17 1974-07-02 Rexall Drug Chemical Process for preparation of substituted 3,4-(diphenyl)chromans
HK38179A (en) * 1973-12-19 1979-06-22 Fisons Ltd Topical compositions
US4447622A (en) * 1981-09-22 1984-05-08 Council Of Scientific And Industrial Research Rafi Marg Preparation of l- and d-isomers of dl-3,4-trans-2,2-disubstituted-3,4-diarylchromans and derivatives thereof
GB8604528D0 (en) * 1986-02-24 1986-04-03 Ici Plc Therapeutic agents
US4742066A (en) * 1986-03-17 1988-05-03 Charles Of The Ritz Group Ltd. Skin treatment composition and method
US5015661A (en) * 1988-08-09 1991-05-14 Hoffmann-La Roche Inc. Chromanes and their pharmaceutical compositions and methods
WO1990012010A1 (en) * 1989-04-07 1990-10-18 Pfizer Inc. Substituted chromans in the treatment of asthma, arthritis and related diseases
US5248777A (en) * 1989-09-19 1993-09-28 Allergan, Inc. Process and intermediates for preparing compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity
US5302606A (en) * 1990-04-16 1994-04-12 Rhone-Poulenc Rorer Pharmaceuticals Inc. Styryl-substituted pyridyl compounds which inhibit EGF receptor tyrosine kinase
WO1992006084A1 (en) * 1990-10-09 1992-04-16 Allergan, Inc. Chromans and thiochromans with retinoid-like activity
US5409930A (en) * 1991-05-10 1995-04-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
AU667889B2 (en) * 1992-04-06 1996-04-18 Merrell Dow Pharmaceuticals Inc. Novel cardioprotective agents
DE69306770T2 (de) * 1992-04-07 1997-06-12 Merrell Pharmaceuticals Inc N Hydrazid-derivate von 3,4-dihydro-2h-1-benzopyranen

Also Published As

Publication number Publication date
DE69424777T2 (de) 2000-11-30
DK0688215T3 (da) 2000-09-11
US5451603A (en) 1995-09-19
PT688215E (pt) 2000-10-31
EP0688215A1 (en) 1995-12-27
US5480903A (en) 1996-01-02
JPH08506347A (ja) 1996-07-09
WO1994020099A1 (en) 1994-09-15
GR3034186T3 (en) 2000-11-30
DE69424777D1 (de) 2000-07-06
CA2158036C (en) 1999-07-20
EP0688215B1 (en) 2000-05-31
ATE193442T1 (de) 2000-06-15
CA2158036A1 (en) 1994-09-15

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