ES2162615T3 - Metodo para tratar o prevenir diabetes de tipo 1 mediante la administracion oral de insulina. - Google Patents

Metodo para tratar o prevenir diabetes de tipo 1 mediante la administracion oral de insulina.

Info

Publication number
ES2162615T3
ES2162615T3 ES91918981T ES91918981T ES2162615T3 ES 2162615 T3 ES2162615 T3 ES 2162615T3 ES 91918981 T ES91918981 T ES 91918981T ES 91918981 T ES91918981 T ES 91918981T ES 2162615 T3 ES2162615 T3 ES 2162615T3
Authority
ES
Spain
Prior art keywords
diabetes
treat
insulin administration
oral insulin
prevent type
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91918981T
Other languages
English (en)
Inventor
Howard L Weiner
George Eisenbarth
David A Hafler
Zhengri Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Autoimmune Inc
Original Assignee
Autoimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Autoimmune Inc filed Critical Autoimmune Inc
Application granted granted Critical
Publication of ES2162615T3 publication Critical patent/ES2162615T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

AQUI DENTRO SE PRESENTAN LOS METODOS PARA EL TRATAMIENTO O PREVENCION DE UNA ENFERMEDAD EN MAMIFEROS CON LAS CARACTERISTICAS DE LA DIABETES TIPO 1 QUE CONSISTEN EN ADMINISTRAR A DICHOS MAMIFEROS INSULINA O FRAGMENTOS DE INSULINA SUPRESORES DE LA ENFERMEDAD O ANALOGOS DE LOS MISMOS A MODO DE DOSIS ORALES O DE AEROSOL. TAMBIEN SE PRESENTAN AQUI DENTRO LAS FORMAS DE DOSIFICACION O FORMULACION FARMACEUTICAS PARA UTILIZARLAS EN LOS METODOS.
ES91918981T 1990-10-10 1991-10-10 Metodo para tratar o prevenir diabetes de tipo 1 mediante la administracion oral de insulina. Expired - Lifetime ES2162615T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59546890A 1990-10-10 1990-10-10

Publications (1)

Publication Number Publication Date
ES2162615T3 true ES2162615T3 (es) 2002-01-01

Family

ID=24383359

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91918981T Expired - Lifetime ES2162615T3 (es) 1990-10-10 1991-10-10 Metodo para tratar o prevenir diabetes de tipo 1 mediante la administracion oral de insulina.

Country Status (15)

Country Link
US (5) US5763396A (es)
EP (1) EP0552256B1 (es)
JP (1) JP2548056B2 (es)
KR (1) KR100239743B1 (es)
AT (1) ATE204178T1 (es)
AU (1) AU659419B2 (es)
BR (1) BR9106977A (es)
CA (1) CA2093806C (es)
DE (1) DE69132688T2 (es)
DK (1) DK0552256T3 (es)
ES (1) ES2162615T3 (es)
HU (2) HU225054B1 (es)
IL (1) IL99699A (es)
NO (1) NO319370B1 (es)
WO (1) WO1992006704A1 (es)

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US5843886A (en) 1998-12-01
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US5763396A (en) 1998-06-09
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BR9106977A (pt) 1993-08-31
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US20010056063A1 (en) 2001-12-27
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US5643868A (en) 1997-07-01
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