US4401820A
(en)
|
1981-01-23 |
1983-08-30 |
Tanabe Seiyaku Co., Ltd. |
Process for racemizing optically active α-amino acids or a salt thereof
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
WO1988007089A1
(en)
|
1987-03-18 |
1988-09-22 |
Medical Research Council |
Altered antibodies
|
US5262296A
(en)
|
1988-03-30 |
1993-11-16 |
Toray Industries, Inc. |
Freeze-dried composition containing enzyme-labeled anti-human interferon-β antibody and enzyme immunoassay kit containing the composition
|
DE68908175T2
(de)
|
1988-05-27 |
1994-03-03 |
Centocor Inc |
Gefriergetrocknete formulierung für antikörperprodukte.
|
ATE231002T1
(de)
|
1992-09-16 |
2003-02-15 |
Scripps Research Inst |
Menschliche, neutralisierende, monoklonale antikörper gegen das respiratorische synzytialvirus
|
BR9609743A
(pt)
|
1995-07-27 |
1999-03-02 |
Genentech Inc |
Formulação reconstituída estável método para a preparação de uma formulação artigo manufaturado e uso da formação
|
US6267958B1
(en)
*
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
ZA966075B
(en)
|
1995-07-27 |
1998-01-19 |
Genentech Inc |
Protein formulation.
|
WO1997010846A1
(en)
|
1995-09-18 |
1997-03-27 |
Intracel Corporation |
Neutralizing monoclonal antibodies to respiratory syncytial virus
|
US7365166B2
(en)
|
1997-04-07 |
2008-04-29 |
Genentech, Inc. |
Anti-VEGF antibodies
|
US6171586B1
(en)
|
1997-06-13 |
2001-01-09 |
Genentech, Inc. |
Antibody formulation
|
JP2002531466A
(ja)
|
1998-12-01 |
2002-09-24 |
プロテイン デザイン ラブス, インコーポレイテッド |
γ−インターフェロンに対するヒト化抗体
|
DK2193809T3
(en)
|
1999-02-22 |
2015-05-26 |
Univ Connecticut |
The albumin-free Factor VIII formulation
|
AR022890A1
(es)
|
1999-03-11 |
2002-09-04 |
Schering Corp |
Citoquinas mamiferas; reactivos relacionados y metodos
|
US7090847B1
(en)
|
1999-09-09 |
2006-08-15 |
Schering Corporation |
Mammalian cytokines; related reagents and methods
|
ATE389019T1
(de)
|
1999-09-09 |
2008-03-15 |
Schering Corp |
Interleukin-12 p40 und interleukin-b30. kombinationen davon. antikörper. verwendungen in pharmazeutische zusammensetzungen
|
AU1102401A
(en)
|
1999-10-22 |
2001-05-08 |
Ludwig Institute For Cancer Research |
Methods for reducing the effects of cancers that express a33 antigen using a33 antigen specific immunoglobulin products
|
US8703126B2
(en)
|
2000-10-12 |
2014-04-22 |
Genentech, Inc. |
Reduced-viscosity concentrated protein formulations
|
DK1324776T4
(en)
|
2000-10-12 |
2018-05-28 |
Genentech Inc |
CONCENTRATED PROTEIN FORMULATIONS WITH REDUCED VISCOSITY
|
US6818216B2
(en)
|
2000-11-28 |
2004-11-16 |
Medimmune, Inc. |
Anti-RSV antibodies
|
EP1345968A2
(en)
|
2000-12-28 |
2003-09-24 |
Altus Biologics Inc. |
Crystals of whole antibodies and fragments thereof and methods for making and using them
|
EP1801123A3
(en)
|
2000-12-28 |
2007-11-21 |
Altus Pharmaceuticals Inc. |
Crystals of whole antibodies and fragments thereof and methods for making and using them
|
US6955717B2
(en)
|
2001-05-01 |
2005-10-18 |
Medimmune Inc. |
Crystals and structure of Synagis Fab
|
GB0113179D0
(en)
|
2001-05-31 |
2001-07-25 |
Novartis Ag |
Organic compounds
|
EP1492554B1
(en)
|
2001-06-21 |
2019-08-21 |
Althea Technologies, Inc. |
Spherical protein particles
|
JP4212470B2
(ja)
|
2001-06-26 |
2009-01-21 |
アムジェン フレモント インク. |
Opglへの抗体
|
WO2003009817A2
(en)
|
2001-07-25 |
2003-02-06 |
Protein Design Labs, Inc. |
Stable lyophilized pharmaceutical formulation of igg antibodies
|
ATE556591T1
(de)
|
2001-11-08 |
2012-05-15 |
Abbott Biotherapeutics Corp |
Stabile pharmazeutische flüssigformulierung von igg-antikörpern
|
DE10207178A1
(de)
|
2002-02-19 |
2003-09-04 |
Novosom Ag |
Komponenten für die Herstellung amphoterer Liposomen
|
PL215168B1
(pl)
|
2002-02-27 |
2013-10-31 |
Immunex Corp |
Formulacja polipeptydowa
|
AU2003226356A1
(en)
|
2002-04-12 |
2003-10-27 |
Ramot At Tel Aviv University Ltd. |
Prevention of brain inflammation as a result of induced autoimmune response
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
EP2243493A1
(en)
|
2002-07-03 |
2010-10-27 |
Ono Pharmaceutical Co., Ltd. |
Immunopotentiative composition
|
US20040033228A1
(en)
|
2002-08-16 |
2004-02-19 |
Hans-Juergen Krause |
Formulation of human antibodies for treating TNF-alpha associated disorders
|
AU2003265361A1
(en)
|
2002-08-28 |
2004-03-19 |
Pharmacia Corporation |
Stable ph optimized formulation of a modified antibody
|
EP2277532A1
(en)
|
2002-09-11 |
2011-01-26 |
Genentech, Inc. |
Novel composition and methods for the treatment of immune related diseases
|
WO2004055164A2
(en)
|
2002-12-13 |
2004-07-01 |
Abgenix, Inc. |
System and method for stabilizing antibodies with histidine
|
MXPA05006828A
(es)
|
2002-12-23 |
2005-09-08 |
Wyeth Corp |
Anticuerpos contra pd-1, y sus usos.
|
EP2270051B1
(en)
|
2003-01-23 |
2019-05-15 |
Ono Pharmaceutical Co., Ltd. |
Antibody specific for human PD-1 and CD3
|
WO2004071517A2
(en)
|
2003-02-06 |
2004-08-26 |
Schering Corporation |
Uses of il-23 related reagents
|
DK2236154T3
(en)
|
2003-02-10 |
2018-06-25 |
Biogen Ma Inc |
IMMUNOGLOBULIN INFORMATION AND METHOD OF PREPARING IT
|
CN1759123B
(zh)
|
2003-03-10 |
2011-04-13 |
先灵公司 |
Il-23激动剂及拮抗剂的用途;相关试剂
|
LT2335725T
(lt)
|
2003-04-04 |
2017-01-25 |
Genentech, Inc. |
Didelės koncentracijos antikūno ir baltymo kompozicijos
|
BRPI0410260A
(pt)
|
2003-05-14 |
2006-05-16 |
Immunogen Inc |
composição conjugada para medicamento
|
EP1498123A1
(en)
|
2003-07-18 |
2005-01-19 |
Aventis Pharma S.A. |
Emulsifying systems containing azetidine derivatives
|
ATE518888T1
(de)
|
2003-10-09 |
2011-08-15 |
Chugai Pharmaceutical Co Ltd |
Stabilisierte lösung mit hoher igm-konzentration
|
US8277810B2
(en)
|
2003-11-04 |
2012-10-02 |
Novartis Vaccines & Diagnostics, Inc. |
Antagonist anti-CD40 antibodies
|
PE20050925A1
(es)
|
2003-11-10 |
2005-11-29 |
Schering Corp |
Anticuerpo recombinante humanizado anti-interleuquina 10
|
DE10355904A1
(de)
|
2003-11-29 |
2005-06-30 |
Merck Patent Gmbh |
Feste Formen von anti-EGFR-Antikörpern
|
US20070184050A1
(en)
|
2003-12-25 |
2007-08-09 |
Kirin Beer Kabushiki Kaisha |
Stable water-based medicinal preparation containing antibody
|
KR101352853B1
(ko)
|
2004-01-07 |
2014-02-04 |
조마 테크놀로지 리미티드 |
M-csf-특이적 단일클론 항체 및 그것의 사용
|
CN1953768B
(zh)
|
2004-02-12 |
2010-10-13 |
默克专利有限公司 |
抗-egfr抗体的高浓缩液体制剂
|
ATE533502T1
(de)
|
2004-02-17 |
2011-12-15 |
Schering Corp |
Verfahren zur modulation der il-23-aktivität; relevante reagenzien
|
BRPI0509177A
(pt)
|
2004-03-24 |
2007-09-18 |
Pdl Biopharma Inc |
uso de anticorpos anti-alfa5beta1 para inibir a proliferação de células cancerìgenas
|
AU2005249360B2
(en)
|
2004-04-12 |
2011-07-21 |
Medimmune, Llc |
Anti-IL-9 antibody formulations and uses thereof
|
DE602005022871D1
(de)
|
2004-06-07 |
2010-09-23 |
Univ Ramot |
Verfahren zur passiven immunisierung gegen eine durch amyloidaggregation gekennzeichnete krankheit oder erkrankung mit vermindertem nervenentzündungsrisiko
|
AR049390A1
(es)
|
2004-06-09 |
2006-07-26 |
Wyeth Corp |
Anticuerpos contra la interleuquina-13 humana y usos de los mismos
|
KR20070040824A
(ko)
|
2004-07-30 |
2007-04-17 |
리나트 뉴로사이언스 코퍼레이션 |
아밀로이드-베타 펩티드에 대해 지시된 항체 및 이의 사용방법
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
US20080057070A1
(en)
|
2004-11-04 |
2008-03-06 |
Chiron Corporation |
Antagonist Anti-Cd40 Monoclonal Antibodies and Methods for Their Use
|
JP2008528638A
(ja)
|
2005-01-28 |
2008-07-31 |
ワイス |
ポリペプチドの安定化液体処方
|
GT200600031A
(es)
|
2005-01-28 |
2006-08-29 |
|
Formulacion anticuerpo anti a beta
|
DOP2006000029A
(es)
|
2005-02-07 |
2006-08-15 |
Genentech Inc |
Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas)
|
US20090110681A1
(en)
|
2005-03-08 |
2009-04-30 |
Pfizer, Inc. |
Anti-M-CSF Antibody Compositions
|
WO2006112838A1
(en)
|
2005-04-18 |
2006-10-26 |
Xtl Biopharmaceuticals Ltd. |
Stabilized anti-hepatitis b (hbv) antibody formulations
|
KR100978684B1
(ko)
|
2005-04-22 |
2010-08-31 |
일라이 릴리 앤드 캄파니 |
Tgf 베타 1 특이적 항체
|
SI2161336T1
(sl)
|
2005-05-09 |
2013-11-29 |
Ono Pharmaceutical Co., Ltd. |
Humana monoklonska protitelesa za programirano smrt 1 (PD-1) in postopki za zdravljenje raka ob uporabi anti-PD-1 protiteles samih ali v kombinaciji z drugimi imunoterapevtiki
|
EP1891110A2
(en)
|
2005-06-07 |
2008-02-27 |
Esbatech AG |
STABLE AND SOLUBLE ANTIBODIES INHIBITING TNF-alpha
|
AU2006259536A1
(en)
|
2005-06-15 |
2006-12-28 |
Schering Corporation |
Anti-IGF1R antibody formulations
|
EP1896073B1
(en)
|
2005-06-30 |
2013-03-06 |
Janssen Biotech, Inc. |
Anti-il-23 antibodies, compositions, methods and uses
|
WO2007016562A2
(en)
|
2005-07-29 |
2007-02-08 |
Amgen Inc. |
Formulations that inhibit protein aggregation
|
NZ623901A
(en)
|
2005-08-03 |
2015-10-30 |
Immunogen Inc |
Immunoconjugate formulations
|
MX2008002179A
(es)
|
2005-08-25 |
2008-04-22 |
Lilly Co Eli |
Anticuerpos anti-il-23.
|
ES2619845T3
(es)
|
2005-08-31 |
2017-06-27 |
Merck Sharp & Dohme Corp. |
Anticuerpos anti-IL-23 diseñados por ingeniería genética
|
US20070065437A1
(en)
|
2005-09-12 |
2007-03-22 |
Greg Elson |
Anti-CD3 antibody formulations
|
PL1942939T5
(pl)
|
2005-09-30 |
2021-10-11 |
Medimmune Limited |
Kompozycja przeciwciała interleukiny-13
|
EP1977763A4
(en)
|
2005-12-28 |
2010-06-02 |
Chugai Pharmaceutical Co Ltd |
STABILIZER PREPARATION CONTAINING ANTIBODIES
|
ES2517420T3
(es)
|
2005-12-29 |
2014-11-03 |
Janssen Biotech, Inc. |
Anticuerpos anti-IL-23 humanos, composiciones, procedimientos y usos
|
EP1988922A4
(en)
|
2006-02-03 |
2010-06-02 |
Medimmune Llc |
PROTEIN FORMULATIONS
|
CN101410137A
(zh)
|
2006-03-28 |
2009-04-15 |
霍夫曼-拉罗奇有限公司 |
抗-igf-1r人单克隆抗体制剂
|
AU2007240732B2
(en)
|
2006-04-21 |
2013-07-04 |
Amgen, Inc. |
Buffering agents for biopharmaceutical formulations
|
NZ571757A
(en)
*
|
2006-04-21 |
2012-01-12 |
Novartis Ag |
Antagonist anti-CD40 antibody pharmaceutical compositions comprising arginine-HCl and a citrate or citric acid buffer
|
WO2007147019A2
(en)
|
2006-06-13 |
2007-12-21 |
Zymogenetics, Inc. |
Il-17 and il-23 antagonists and methods of using the same
|
CA2665567C
(en)
|
2006-10-06 |
2012-07-03 |
Amgen Inc. |
Stable formulations
|
US7705132B2
(en)
|
2006-10-20 |
2010-04-27 |
Amgen Inc. |
Stable polypeptide formulations
|
KR20150002896A
(ko)
|
2006-10-27 |
2015-01-07 |
애브비 바이오테크놀로지 리미티드 |
결정형 항-hTNF알파 항체
|
EA017549B1
(ru)
|
2006-12-05 |
2013-01-30 |
Круселл Холланд Б.В. |
Стабильные жидкие композиции антител против вируса бешенства
|
US8232372B2
(en)
|
2006-12-14 |
2012-07-31 |
Schering Corp. |
Engineered anti-TSLP antibody
|
MX2009006594A
(es)
|
2006-12-21 |
2009-08-12 |
Amgen Inc |
Formulaciones de ph regulado y estables que contienen polipeptidos.
|
CN101600457B
(zh)
*
|
2007-01-09 |
2014-01-08 |
惠氏公司 |
抗il-13抗体调配物和其用途
|
TWI426918B
(zh)
|
2007-02-12 |
2014-02-21 |
Merck Sharp & Dohme |
Il-23拮抗劑於治療感染之用途
|
US20100055111A1
(en)
|
2007-02-14 |
2010-03-04 |
Med. College Of Georgia Research Institute, Inc. |
Indoleamine 2,3-dioxygenase, pd-1/pd-l pathways, and ctla4 pathways in the activation of regulatory t cells
|
CN103396489A
(zh)
|
2007-02-23 |
2013-11-20 |
默沙东公司 |
工程改造的抗IL-23p19抗体
|
HUE042172T2
(hu)
|
2007-02-23 |
2019-06-28 |
Merck Sharp & Dohme |
Genetikailag elõállított anti-il-23P19 antitestek
|
CN101679507A
(zh)
|
2007-03-29 |
2010-03-24 |
艾博特公司 |
结晶抗人类il-12抗体
|
AU2008232902B2
(en)
|
2007-03-30 |
2013-10-03 |
Medlmmune, Llc |
Antibody formulation
|
TWI614028B
(zh)
|
2007-06-14 |
2018-02-11 |
百健Ma公司 |
抗體調配物
|
US20090208492A1
(en)
|
2007-06-14 |
2009-08-20 |
Elan Pharmaceuticals, Inc. |
Lyophilized Immunoglobulin Formulations and Methods of Preparation
|
EP2535354B1
(en)
|
2007-06-18 |
2017-01-11 |
Merck Sharp & Dohme B.V. |
Antibodies to human programmed death receptor pd-1
|
US7951368B2
(en)
|
2007-06-25 |
2011-05-31 |
Amgen Inc. |
Compositions of specific binding agents to hepatocyte growth factor
|
UA107557C2
(xx)
|
2007-07-06 |
2015-01-26 |
|
Композиція антитіла офатумумабу
|
US20100286038A1
(en)
|
2007-09-21 |
2010-11-11 |
Valentyn Antochshuk |
Formulation containing cyclin-dependent kinase inhibiting compound and method of treating tumors using the same
|
EP2205276A4
(en)
|
2007-09-28 |
2012-08-15 |
Janssen Biotech Inc |
ANTI-IL-12 / 23P40 ANTIBODIES, EPITOPES, FORMULATIONS, COMPOSITIONS, METHODS AND USES
|
AR068723A1
(es)
|
2007-10-05 |
2009-12-02 |
Glaxo Group Ltd |
Proteina que se une a antigenos que se une a il-23 humana y sus usos
|
EP2225275A4
(en)
|
2007-11-28 |
2013-04-03 |
Medimmune Llc |
PROTEIN FORMULATION
|
CN105126099A
(zh)
|
2007-12-21 |
2015-12-09 |
弗·哈夫曼-拉罗切有限公司 |
抗体制剂
|
PE20091174A1
(es)
|
2007-12-27 |
2009-08-03 |
Chugai Pharmaceutical Co Ltd |
Formulacion liquida con contenido de alta concentracion de anticuerpo
|
CN101951885A
(zh)
|
2007-12-28 |
2011-01-19 |
生物发明国际公司 |
制剂
|
BRPI0908361A2
(pt)
|
2008-02-07 |
2015-04-07 |
Amgen Inc |
Seringas previamente cheias contendo composição e métodos de preparação das mesmas e de estabilização de agente de ligação específico em composição.
|
CN104548091A
(zh)
|
2008-02-11 |
2015-04-29 |
治疗科技公司 |
用于肿瘤治疗的单克隆抗体
|
WO2009120684A1
(en)
|
2008-03-25 |
2009-10-01 |
Medimmune, Llc |
Antibody formulation
|
HUE036780T2
(hu)
|
2008-04-09 |
2018-07-30 |
Genentech Inc |
Új kompozíciók és eljárások immunológiai vonatkozású betegségek kezelésére
|
AR072001A1
(es)
|
2008-06-03 |
2010-07-28 |
Abbott Lab |
Inmunoglobulina con dominio variable dual y usos de la misma
|
JP5945096B2
(ja)
|
2008-07-04 |
2016-07-05 |
小野薬品工業株式会社 |
抗ヒトpd−1抗体の癌に対する治療効果を最適化するための判定マーカーの使用
|
US8263748B2
(en)
|
2008-08-27 |
2012-09-11 |
Schering Corporation |
Lyophilized formulations of engineered anti-IL-23p19 antibodies
|
CN102159204B
(zh)
|
2008-09-19 |
2015-04-01 |
辉瑞公司 |
稳定的液体抗体制剂
|
EP3011953A1
(en)
|
2008-10-29 |
2016-04-27 |
Ablynx N.V. |
Stabilised formulations of single domain antigen binding molecules
|
WO2010062372A2
(en)
|
2008-11-03 |
2010-06-03 |
President And Fellows Of Harvard College |
Methods for modulating nf-kb using gibberellins
|
CN102281902B
(zh)
|
2008-11-17 |
2013-11-13 |
弗·哈夫曼-拉罗切有限公司 |
用于减少大分子在生理条件下聚集的方法和制剂
|
WO2010069858A1
(en)
|
2008-12-19 |
2010-06-24 |
F. Hoffmann-La Roche Ag |
Pharmaceutical composition
|
KR20110128333A
(ko)
|
2009-03-06 |
2011-11-29 |
제넨테크, 인크. |
항체 제제
|
RU2011140486A
(ru)
*
|
2009-03-06 |
2013-04-20 |
МЕДИММЬЮН, ЭлЭлСи |
Композиции, содержащие гуманизированные антитела к cd19
|
EP2230312A1
(en)
|
2009-03-19 |
2010-09-22 |
Helmholtz-Zentrum für Infektionsforschung GmbH |
Probe compound for detecting and isolating enzymes and means and methods using the same
|
SG175188A1
(en)
|
2009-05-04 |
2011-11-28 |
Abbott Biotech Ltd |
Stable high protein concentration formulations of human anti-tnf-alpha-antibodies
|
US9155745B2
(en)
|
2009-06-16 |
2015-10-13 |
Universite De Geneve |
Bevacizumab formulations with lower aggregation propensity, comprising corticosteroid anti-inflammatory drugs
|
JP2012533548A
(ja)
|
2009-07-14 |
2012-12-27 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
組成物における黄色形成および過酸化物形成を阻害する方法
|
WO2011017070A1
(en)
|
2009-07-28 |
2011-02-10 |
Merck Sharp & Dohme Corp. |
Methods for producing high concentration lyophilized pharmaceutical formulations
|
US9345661B2
(en)
|
2009-07-31 |
2016-05-24 |
Genentech, Inc. |
Subcutaneous anti-HER2 antibody formulations and uses thereof
|
WO2011024862A1
(ja)
|
2009-08-31 |
2011-03-03 |
三洋化成工業株式会社 |
タンパク質水溶液の安定化剤、この安定化剤を含有するタンパク質水溶液及び液体洗剤組成物、並びに、この安定化剤を用いるタンパク質の安定化方法
|
PL3023438T3
(pl)
|
2009-09-03 |
2020-07-27 |
Merck Sharp & Dohme Corp. |
Przeciwciała anty-gitr
|
US20110059079A1
(en)
|
2009-09-04 |
2011-03-10 |
Xoma Technology Ltd. |
Antibody Coformulations
|
JP5700581B2
(ja)
|
2009-09-15 |
2015-04-15 |
アジノモト アルシア, インコーポレイテッド |
プロテインaの結晶および架橋した結晶ならびにその使用方法
|
KR101898739B1
(ko)
|
2009-11-04 |
2018-09-13 |
머크 샤프 앤드 돔 코포레이션 |
조작된 항-tslp 항체
|
TWI623323B
(zh)
|
2009-12-21 |
2018-05-11 |
建南德克公司 |
抗體調配物
|
TWI505838B
(zh)
|
2010-01-20 |
2015-11-01 |
Chugai Pharmaceutical Co Ltd |
Stabilized antibody solution containing
|
US8513236B2
(en)
|
2010-02-03 |
2013-08-20 |
Laurus Labs Private Limited |
Pterostilbene cocrystals
|
AU2011227335B2
(en)
|
2010-03-17 |
2014-11-06 |
Abbott Research B.V. |
Anti-nerve growth factor (NGF) antibody compositions
|
BR112012027828A2
(pt)
|
2010-05-03 |
2016-08-09 |
Genentech Inc |
composição de matéria, artigo de fabricação e método de redução da viscosidade de uma formulação contendo proteína e de preparação de uma formulação aquosa contendo proteína
|
US8933075B2
(en)
|
2010-06-17 |
2015-01-13 |
Fuzians Biomedicals, Inc. |
Compounds useful as antiviral agents, compositions, and methods of use
|
EP2399604A1
(en)
|
2010-06-25 |
2011-12-28 |
F. Hoffmann-La Roche AG |
Novel antibody formulation
|
FR2962908A1
(fr)
|
2010-07-20 |
2012-01-27 |
Lfb Biotechnologies |
Formulation d'anticorps anti-cd20
|
WO2012018538A2
(en)
|
2010-07-26 |
2012-02-09 |
Schering Corporation |
Bioassays for determining pd-1 modulation
|
EA034617B1
(ru)
|
2010-10-06 |
2020-02-27 |
Ридженерон Фармасьютикалз, Инк. |
Дозированная форма жидкой фармацевтической композиции, содержащей антитела к рецептору интерлейкина-4 (il-4r)
|
KR20140018315A
(ko)
|
2011-03-25 |
2014-02-12 |
암젠 인크 |
항스클러로스틴 항체 결정 및 이의 제제
|
KR102031020B1
(ko)
*
|
2011-03-31 |
2019-10-14 |
머크 샤프 앤드 돔 코포레이션 |
인간 프로그램화된 사멸 수용체 pd-1에 대한 항체의 안정한 제제 및 관련된 치료
|
JP2014510152A
(ja)
|
2011-04-07 |
2014-04-24 |
グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー |
粘度が低減された処方物
|
UY34105A
(es)
|
2011-06-03 |
2012-07-31 |
Lg Life Sciences Ltd |
Formulación líquida estable de etanercept
|
WO2013012022A1
(ja)
|
2011-07-19 |
2013-01-24 |
中外製薬株式会社 |
アルギニンアミドまたはその類似化合物を含む安定なタンパク質含有製剤
|
CN107522664B
(zh)
|
2011-10-27 |
2021-03-16 |
麻省理工学院 |
能够形成药物包封微球的在n末端上官能化的氨基酸衍生物
|
EA033387B1
(ru)
|
2012-01-23 |
2019-10-31 |
Regeneron Pharma |
СТАБИЛИЗИРОВАННЫЕ СОСТАВЫ, СОДЕРЖАЩИЕ АНТИТЕЛА ПРОТИВ Ang-2
|
WO2013164837A1
(en)
|
2012-03-07 |
2013-11-07 |
Cadila Healthcare Limited |
Pharmaceutical formulations of tnf-alpha antibodies
|
WO2013151999A1
(en)
|
2012-04-02 |
2013-10-10 |
President And Fellows Of Harvard College |
Cancer treatment and immune system regulation through fat10 pathway inhibition
|
KR102124758B1
(ko)
|
2012-05-03 |
2020-06-19 |
베링거 인겔하임 인터내셔날 게엠베하 |
항-il-23p19 항체
|
US20140004131A1
(en)
|
2012-05-04 |
2014-01-02 |
Novartis Ag |
Antibody formulation
|
EP2866833B1
(en)
|
2012-06-27 |
2019-05-15 |
Merck Sharp & Dohme Corp. |
Crystalline anti-human il-23 antibodies
|
KR102090849B1
(ko)
|
2012-07-04 |
2020-03-19 |
에프. 호프만-라 로슈 아게 |
공유 결합된 항원-항체 접합체
|
FR2994390B1
(fr)
|
2012-08-10 |
2014-08-15 |
Adocia |
Procede d'abaissement de la viscosite de solutions de proteines a concentration elevee
|
WO2014031718A1
(en)
|
2012-08-23 |
2014-02-27 |
Merck Sharp & Dohme Corp. |
Stable formulations of antibodies to tslp
|
US9592297B2
(en)
|
2012-08-31 |
2017-03-14 |
Bayer Healthcare Llc |
Antibody and protein formulations
|
US8883979B2
(en)
|
2012-08-31 |
2014-11-11 |
Bayer Healthcare Llc |
Anti-prolactin receptor antibody formulations
|
EP2919812A4
(en)
|
2012-11-19 |
2016-05-18 |
Merck Sharp & Dohme |
Liquid formulations for TNFR: FC fusion proteins
|
EP2931311A4
(en)
|
2012-12-13 |
2016-08-17 |
Merck Sharp & Dohme |
LYOPHILIZED BALLULAR PELLETS OF ANTI-IL-23 ANTIBODIES
|
US9700633B2
(en)
|
2013-01-28 |
2017-07-11 |
Jenkem Technology Co., Ltd., Tianjin Branch |
Conjugates of water soluble polymer-amino acid oligopeptide-drug, preparation method and use thereof
|
KR20210024245A
(ko)
*
|
2013-03-13 |
2021-03-04 |
시애틀 지네틱스, 인크. |
사이클로덱스트린 및 항체-약물 포합체 제형
|
WO2014193898A1
(en)
*
|
2013-05-31 |
2014-12-04 |
Merck Sharp & Dohme Corp. |
Combination therapies for cancer
|
PT3021869T
(pt)
|
2013-07-16 |
2020-09-10 |
Hoffmann La Roche |
Métodos de tratamento do cancro com antagonistas da ligação ao eixo pd-1 e inibidores do tigit
|
MX370207B
(es)
|
2013-07-23 |
2019-12-05 |
Novaliq Gmbh |
Composiciones estabilizadas de anticuerpos.
|
TWI649308B
(zh)
|
2013-07-24 |
2019-02-01 |
小野藥品工業股份有限公司 |
喹啉衍生物
|
KR20240042200A
(ko)
|
2013-09-11 |
2024-04-01 |
이글 바이오로직스 인코퍼레이티드 |
점도저하제를 함유하는 액체 단백질 제형
|
RS64268B1
(sr)
|
2013-09-20 |
2023-07-31 |
Bristol Myers Squibb Co |
Kombinacija anti-lag-3 antitela i anti-pd-1 antitela za lečenje tumora
|
CA2927434C
(en)
|
2013-10-16 |
2022-07-19 |
Merck Sharp & Dohme Corp. |
Method of obtaining thermostable dried vaccine formulations
|
US20170107300A1
(en)
|
2014-03-21 |
2017-04-20 |
The Brigham And Women's Hospital, Inc. |
Methods and compositions for treatment of immune-related diseases or disorders and/or therapy monitoring
|
RU2589691C2
(ru)
|
2014-06-16 |
2016-07-10 |
Общество с ограниченной ответственностью "Промоген-МАТ" |
Стабильная композиция антитела, специфически связывающегося с her2 рецепторами, и способ ее получения
|
US20160074515A1
(en)
|
2014-06-20 |
2016-03-17 |
Reform Biologics, Llc |
Viscosity-reducing excipient compounds for protein formulations
|
KR20170052569A
(ko)
|
2014-07-18 |
2017-05-12 |
어드박시스, 인크. |
전립선암 치료용 pd-1 길항제 및 리스테리아 기반 백신의 병용
|
CN105296433B
(zh)
|
2014-08-01 |
2018-02-09 |
中山康方生物医药有限公司 |
一种ctla4抗体、其药物组合物及其用途
|
WO2016024231A1
(en)
|
2014-08-11 |
2016-02-18 |
Acerta Pharma B.V. |
Therapeutic combinations of a btk inhibitor, a pi3k inhibitor, a jak-2 inhibitor, a pd-1 inhibitor and/or a pd-l1 inhibitor
|
MX2017002229A
(es)
|
2014-08-19 |
2017-05-09 |
Merck Sharp & Dohme |
Anticuerpos anti tigit.
|
JO3663B1
(ar)
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
CN107530419B
(zh)
|
2014-10-31 |
2021-05-18 |
昂考梅德药品有限公司 |
治疗疾病的组合疗法
|
WO2016081384A1
(en)
|
2014-11-17 |
2016-05-26 |
Genentech, Inc. |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
WO2016100882A1
(en)
|
2014-12-19 |
2016-06-23 |
Novartis Ag |
Combination therapies
|
US20170360929A1
(en)
|
2014-12-23 |
2017-12-21 |
Pfizer Inc. |
Stable aqueous antibody formulation for anti tnf alpha antibodies
|
JP6180663B2
(ja)
|
2014-12-23 |
2017-08-16 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
Tigitに対する抗体
|
US20170369570A1
(en)
|
2015-01-20 |
2017-12-28 |
Immunexcite, Inc. |
Compositions and methods for cancer immunotherapy
|
JP7115856B2
(ja)
|
2015-02-19 |
2022-08-09 |
コンピュジェン リミテッド |
抗pvrig抗体及び使用方法
|
AR103726A1
(es)
|
2015-02-27 |
2017-05-31 |
Merck Sharp & Dohme |
Cristales de anticuerpos monoclonales anti-pd-1 humanos
|
CA2978226A1
(en)
|
2015-03-04 |
2016-09-09 |
Merck Sharpe & Dohme Corp. |
Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer
|
JP6901400B2
(ja)
*
|
2015-04-03 |
2021-07-14 |
ゾーマ テクノロジー リミテッド |
TGF−β及びPD−1の阻害物質を使用する癌の治療法
|
TN2017000440A1
(en)
|
2015-04-17 |
2019-04-12 |
Bristol Myers Squibb Co |
Compositions comprising a combination of an anti-pd-1 antibody and another antibody
|
US20160362489A1
(en)
|
2015-04-28 |
2016-12-15 |
Bristol-Myers Squibb Company |
Treatment of PD-L1-Positive Melanoma Using an Anti-PD-1 Antibody
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
WO2017009813A1
(en)
|
2015-07-16 |
2017-01-19 |
Laurus Labs Private Limited |
Novel caffeine cocrystals and their polymorphic forms
|
JO3620B1
(ar)
|
2015-08-05 |
2020-08-27 |
Amgen Res Munich Gmbh |
مثبطات نقطة فحص مناعية للاستخدام في علاج سرطانات محمولة عبر الدم
|
WO2017030823A2
(en)
|
2015-08-14 |
2017-02-23 |
Merck Sharp & Dohme Corp. |
Anti-tigit antibodies
|
KR20180080189A
(ko)
|
2015-09-01 |
2018-07-11 |
퍼스트 웨이브 바이오, 인코포레이티드 |
이상 염증 반응과 연관된 질환을 치료하기 위한 방법 및 조성물
|
PT3344654T
(pt)
|
2015-09-02 |
2021-01-26 |
Immutep Sas |
Anticorpos anti-lag-3
|
CA2998589A1
(en)
|
2015-09-14 |
2017-03-23 |
Compass Therapeutics Llc |
Compositions and methods for treating cancer via antagonism of the cd155/tigit pathway and tgf-.beta.
|
RU2732591C2
(ru)
|
2015-09-25 |
2020-09-21 |
Дженентек, Инк. |
Анти-tigit антитела и способы применения
|
US20170097333A1
(en)
|
2015-09-28 |
2017-04-06 |
Merck Sharp & Dohme Corp. |
Cell based assay to measure the t-cell stimulating capacity of anti-lag3 antibodies and other agents
|
CA2999079A1
(en)
|
2015-09-28 |
2017-04-06 |
Jiangsu Hengrui Medicine Co., Ltd. |
Stable anti-pd-1 antibody pharmaceutical preparation and application thereof in medicine
|
UA125062C2
(uk)
|
2015-10-01 |
2022-01-05 |
Потенза Терапеутікс, Інк. |
Анти-tigit антигензв'язуючі білки і способи їх застосування
|
JO3555B1
(ar)
|
2015-10-29 |
2020-07-05 |
Merck Sharp & Dohme |
جسم مضاد يبطل فعالية فيروس الالتهاب الرئوي البشري
|
CN113599533A
(zh)
|
2015-11-25 |
2021-11-05 |
乐高化学生物科学股份有限公司 |
包含分支接头的抗体-药物缀合物及其相关方法
|
WO2017112621A1
(en)
|
2015-12-22 |
2017-06-29 |
Merck Sharp & Dohme Corp. |
Formulations of engineered anti-il-10 antibodies
|
EP3405490B1
(en)
|
2016-01-21 |
2021-10-20 |
Pfizer Inc. |
Mono and bispecific antibodies for epidermal growth factor receptor variant iii and cd3 and their uses
|
LT3458478T
(lt)
|
2016-05-18 |
2021-02-10 |
Boehringer Ingelheim International Gmbh |
Antikūnai prieš pd-1 ir lag-3, skirti vėžio gydymui
|
RU2767357C2
(ru)
|
2016-06-14 |
2022-03-17 |
Ксенкор, Инк. |
Биспецифические антитела-ингибиторы контрольных точек
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
WO2018071919A1
(en)
|
2016-10-14 |
2018-04-19 |
Xencor, Inc. |
IL15/IL15Rα HETERODIMERIC FC-FUSION PROTEINS
|
EP3541413A2
(en)
|
2016-11-21 |
2019-09-25 |
Polpharma Biologics S.A. |
Aqueous pharmaceutical formulations
|
CN110366429A
(zh)
|
2017-03-01 |
2019-10-22 |
免疫医疗有限公司 |
单克隆抗体的配制品
|
TWI761453B
(zh)
|
2017-03-01 |
2022-04-21 |
英商梅迪繆思有限公司 |
抗rsv單株抗體配製物
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
WO2018204343A1
(en)
|
2017-05-02 |
2018-11-08 |
Merck Sharp & Dohme Corp. |
Stable formulations of anti-ctla4 antibodies alone and in combination with programmed death receptor 1 (pd-1) antibodies and methods of use thereof
|
JOP20190260A1
(ar)
|
2017-05-02 |
2019-10-31 |
Merck Sharp & Dohme |
صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
|
RU2019138507A
(ru)
*
|
2017-05-02 |
2021-06-02 |
Мерк Шарп И Доум Корп. |
Составы антител против lag3 и совместные составы антител против lag3 и антител против pd-1
|
JP2020532562A
(ja)
|
2017-09-05 |
2020-11-12 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
生物学的製剤の粘度を低下させるための化合物
|
CA3118144A1
(en)
|
2018-11-07 |
2020-05-14 |
Merck Sharp & Dohme Corp. |
Co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies
|