BR112018008109A2 - métodos para modificar uma sequência de nucleotídeos no genoma de uma célula vegetal, produzir uma planta, produzir tecido de calo de planta que tem uma sequência de nucleotídeos modificada em seu genoma sem o uso de um marcador selecionável, e planta de progênie da planta - Google Patents

métodos para modificar uma sequência de nucleotídeos no genoma de uma célula vegetal, produzir uma planta, produzir tecido de calo de planta que tem uma sequência de nucleotídeos modificada em seu genoma sem o uso de um marcador selecionável, e planta de progênie da planta

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Publication number
BR112018008109A2
BR112018008109A2 BR112018008109A BR112018008109A BR112018008109A2 BR 112018008109 A2 BR112018008109 A2 BR 112018008109A2 BR 112018008109 A BR112018008109 A BR 112018008109A BR 112018008109 A BR112018008109 A BR 112018008109A BR 112018008109 A2 BR112018008109 A2 BR 112018008109A2
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plant
genome
nucleotide sequence
producing
methods
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BR112018008109A
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English (en)
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Mark Cigan Andrew
Svitashev Sergei
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Pioneer Hi Bred Int
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Publication of BR112018008109A2 publication Critical patent/BR112018008109A2/pt

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Abstract

trata-se de composições e métodos para modificar uma sequência de nucleotídeos no genoma de uma célula vegetal sem o uso de um marcador selecionável. os métodos e as composições empregam um sistema de polinucleotídeo-guia/endonuclease cas para produzir uma ruptura de filamento duplo em um sítio-alvo localizado em uma sequência de nucleotídeos, e células vegetais são obtidas sem o uso de um marcador selecionável, e para fornecer um sistema eficaz para modificar sítios-alvo dentro do genoma de uma planta, célula vegetal ou semente. são também fornecidos composições e métodos para produzir uma célula vegetal, tecido de calo ou planta que tem uma sequência de nucleotídeos modificada em seu genoma, sem o uso de um marcador selecionável.
BR112018008109A 2015-10-20 2016-10-17 métodos para modificar uma sequência de nucleotídeos no genoma de uma célula vegetal, produzir uma planta, produzir tecido de calo de planta que tem uma sequência de nucleotídeos modificada em seu genoma sem o uso de um marcador selecionável, e planta de progênie da planta BR112018008109A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562243719P 2015-10-20 2015-10-20
US201662309033P 2016-03-16 2016-03-16
US201662359254P 2016-07-07 2016-07-07
PCT/US2016/057272 WO2017070029A1 (en) 2015-10-20 2016-10-17 Methods and compositions for marker-free genome modification

Publications (1)

Publication Number Publication Date
BR112018008109A2 true BR112018008109A2 (pt) 2018-11-06

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BR112018008109A BR112018008109A2 (pt) 2015-10-20 2016-10-17 métodos para modificar uma sequência de nucleotídeos no genoma de uma célula vegetal, produzir uma planta, produzir tecido de calo de planta que tem uma sequência de nucleotídeos modificada em seu genoma sem o uso de um marcador selecionável, e planta de progênie da planta
BR112018008134A BR112018008134A2 (pt) 2015-10-20 2016-10-17 método para restaurar a função de um produto gênico não funcional no genoma de uma célula, método para editar uma sequência nucleotídica no genoma de uma célula, planta ou planta de progênie, método para editar uma sequência nucleotídica no genoma de uma célula sem o uso de um molde polinucleotídico de modificação e método para entregar um complexo de rna guia/endonuclease cas numa célula

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BR112018008134A BR112018008134A2 (pt) 2015-10-20 2016-10-17 método para restaurar a função de um produto gênico não funcional no genoma de uma célula, método para editar uma sequência nucleotídica no genoma de uma célula, planta ou planta de progênie, método para editar uma sequência nucleotídica no genoma de uma célula sem o uso de um molde polinucleotídico de modificação e método para entregar um complexo de rna guia/endonuclease cas numa célula

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US (3) US20180282763A1 (pt)
EP (2) EP3365440B1 (pt)
JP (2) JP2018531024A (pt)
KR (2) KR20180059535A (pt)
CN (2) CN108138155A (pt)
AU (2) AU2016341041A1 (pt)
BR (2) BR112018008109A2 (pt)
CA (2) CA2996326A1 (pt)
MX (2) MX2018004808A (pt)
WO (2) WO2017070029A1 (pt)
ZA (2) ZA201801578B (pt)

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