BR112014009486A2 - composto, composição farmacêutica, uso de um composto, e, métodos para intensificar a qualidade do sono, para tratamento de insônia e para tratamento ou controle da obesidade - Google Patents

composto, composição farmacêutica, uso de um composto, e, métodos para intensificar a qualidade do sono, para tratamento de insônia e para tratamento ou controle da obesidade

Info

Publication number
BR112014009486A2
BR112014009486A2 BR112014009486A BR112014009486A BR112014009486A2 BR 112014009486 A2 BR112014009486 A2 BR 112014009486A2 BR 112014009486 A BR112014009486 A BR 112014009486A BR 112014009486 A BR112014009486 A BR 112014009486A BR 112014009486 A2 BR112014009486 A2 BR 112014009486A2
Authority
BR
Brazil
Prior art keywords
compound
treating
present
methods
pharmaceutical composition
Prior art date
Application number
BR112014009486A
Other languages
English (en)
Portuguese (pt)
Inventor
W Skudlarek Jason
D Kuduk Scott
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of BR112014009486A2 publication Critical patent/BR112014009486A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BR112014009486A 2011-10-19 2012-10-17 composto, composição farmacêutica, uso de um composto, e, métodos para intensificar a qualidade do sono, para tratamento de insônia e para tratamento ou controle da obesidade BR112014009486A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161548883P 2011-10-19 2011-10-19
PCT/US2012/060479 WO2013059222A1 (en) 2011-10-19 2012-10-17 2-pyridyloxy-4-nitrile orexin receptor antagonists

Publications (1)

Publication Number Publication Date
BR112014009486A2 true BR112014009486A2 (pt) 2017-05-09

Family

ID=47116466

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014009486A BR112014009486A2 (pt) 2011-10-19 2012-10-17 composto, composição farmacêutica, uso de um composto, e, métodos para intensificar a qualidade do sono, para tratamento de insônia e para tratamento ou controle da obesidade

Country Status (11)

Country Link
US (1) US9156819B2 (https=)
EP (1) EP2768823B1 (https=)
JP (1) JP5947906B2 (https=)
CN (1) CN103874695B (https=)
AR (1) AR088352A1 (https=)
AU (1) AU2012326275B2 (https=)
BR (1) BR112014009486A2 (https=)
CA (1) CA2852425C (https=)
IN (1) IN2014CN02515A (https=)
TW (1) TW201317228A (https=)
WO (1) WO2013059222A1 (https=)

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WO2016065583A1 (en) 2014-10-30 2016-05-06 Merck Sharp & Dohme Corp. Oxazole orexin receptor antagonists
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EP3223803A1 (en) * 2014-11-24 2017-10-04 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of ox1r antagonists for the treatment of inflammatory bowel diseases
US9994570B2 (en) 2014-11-26 2018-06-12 Merck Sharp & Dohme Corp. Bridged diazepane orexin receptor antagonists
US10000499B2 (en) 2014-11-26 2018-06-19 Merck Sharp & Dohme Corp. Methyl diazepane orexin receptor antagonists
WO2016086358A1 (en) * 2014-12-02 2016-06-09 Merck Sharp & Dohme Corp. Hydroxymethyl piperidine orexin receptor antagonists
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