BR0206752A - Formulação farmacêutica - Google Patents

Formulação farmacêutica

Info

Publication number
BR0206752A
BR0206752A BR0206752-8A BR0206752A BR0206752A BR 0206752 A BR0206752 A BR 0206752A BR 0206752 A BR0206752 A BR 0206752A BR 0206752 A BR0206752 A BR 0206752A
Authority
BR
Brazil
Prior art keywords
pharmaceutical formulation
subunit
drug substance
dosage form
component
Prior art date
Application number
BR0206752-8A
Other languages
English (en)
Inventor
Stephen Mark Mcallister
Ronald K Raby Jr
Adrian Brown
Allan J Clarke
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of BR0206752A publication Critical patent/BR0206752A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"FORMULAçãO FARMACêUTICA". A presente invenção se refere a composições poliméricas farmaceuticamente aceitáveis adequadas para molde por injeção de formas de dosagem farmacêutica multicomponente ou única compreendendo uma pluralidade de substância de droga contendo subunidades, sendo compartimentos de cápsula e/ou subunidades sólidas compreendendo uma matriz sólida de um polímero que contém uma substância da droga, as subunidades sendo conectadas na forma de dosagem ligada por uma ligação entre partes da forma de dosagem ligada.
BR0206752-8A 2001-01-30 2002-01-30 Formulação farmacêutica BR0206752A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0102342.3A GB0102342D0 (en) 2001-01-30 2001-01-30 Pharmaceutical formulation
PCT/US2002/002698 WO2002060385A2 (en) 2001-01-30 2002-01-30 Pharmaceutical formulation

Publications (1)

Publication Number Publication Date
BR0206752A true BR0206752A (pt) 2004-02-10

Family

ID=9907781

Family Applications (2)

Application Number Title Priority Date Filing Date
BR0206752-8A BR0206752A (pt) 2001-01-30 2002-01-30 Formulação farmacêutica
BR0206627-0A BR0206627A (pt) 2001-01-30 2002-01-30 Formulação farmacêutica

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR0206627-0A BR0206627A (pt) 2001-01-30 2002-01-30 Formulação farmacêutica

Country Status (21)

Country Link
US (3) US8367101B2 (pt)
EP (5) EP1363607B1 (pt)
JP (4) JP2004524300A (pt)
KR (4) KR101128228B1 (pt)
CN (3) CN1489456B (pt)
AR (2) AR032524A1 (pt)
AU (3) AU2002242024B2 (pt)
BR (2) BR0206752A (pt)
CA (2) CA2436416C (pt)
CZ (2) CZ20032003A3 (pt)
ES (1) ES2399838T3 (pt)
GB (1) GB0102342D0 (pt)
HU (2) HUP0302857A3 (pt)
IL (3) IL156783A0 (pt)
MX (2) MXPA03006775A (pt)
NO (2) NO20033143L (pt)
NZ (2) NZ544503A (pt)
PL (2) PL208634B1 (pt)
TW (2) TWI257871B (pt)
WO (2) WO2002060384A2 (pt)
ZA (2) ZA200304810B (pt)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2169880T3 (es) 1996-10-18 2002-07-16 Vertex Pharma Inhibidores de proteasas de serina, particularmente de la proteasa ns3 del virus de la hepatitis c.
EP1204410B1 (en) * 1999-07-30 2012-09-12 Capsugel Belgium NV Multi-component pharmaceutical dosage form
US6991807B2 (en) * 2000-02-24 2006-01-31 Advancis Pharmaceutical, Corp. Antibiotic composition
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6544555B2 (en) * 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
SV2003000617A (es) 2000-08-31 2003-01-13 Lilly Co Eli Inhibidores de la proteasa peptidomimetica ref. x-14912m
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20050175687A1 (en) * 2001-01-30 2005-08-11 Mcallister Stephen M. Pharmaceutical formulations
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US7842308B2 (en) * 2001-01-30 2010-11-30 Smithkline Beecham Limited Pharmaceutical formulation
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US7670612B2 (en) 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
TWI336260B (en) 2002-07-25 2011-01-21 Glaxo Group Ltd Dosage form suitable for retaining drug substance
US8404716B2 (en) * 2002-10-15 2013-03-26 Celgene Corporation Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
US11116782B2 (en) 2002-10-15 2021-09-14 Celgene Corporation Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
US8404717B2 (en) * 2002-10-15 2013-03-26 Celgene Corporation Methods of treating myelodysplastic syndromes using lenalidomide
US7833545B2 (en) * 2003-04-29 2010-11-16 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
NL1023720C2 (nl) * 2003-06-23 2004-12-28 Univ Eindhoven Tech Werkwijze voor het wijzigen van de transporteigenschappen van een materiaal, werkwijze voor het vrijmaken van een werkstof uit een implantaat, evenals implantaat met werkstof.
AU2004258944B2 (en) * 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
AU2004258953B2 (en) * 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
TW200526274A (en) * 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
AU2004258949B2 (en) * 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
AU2004264939A1 (en) * 2003-08-11 2005-02-24 Middlebrook Pharmaceuticals, Inc. Robust pellet
CA2535398C (en) * 2003-08-12 2013-11-12 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
CA2535780A1 (en) * 2003-08-29 2005-03-17 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
TWI359147B (en) 2003-09-05 2012-03-01 Vertex Pharma Inhibitors of serine proteases, particularly hcv n
AU2004273830B2 (en) * 2003-09-15 2011-03-24 Shionogi, Inc. Antibiotic product, use and formulation thereof
US7517581B2 (en) * 2003-09-26 2009-04-14 Parker-Hannifin Corporation Semipermeable hydrophilic membrane
JP2007517039A (ja) * 2003-12-24 2007-06-28 アドバンシス ファーマスーティカル コーポレイション 変性放出製剤の吸収増強
JP2005187376A (ja) 2003-12-25 2005-07-14 Shin Etsu Chem Co Ltd 低置換度セルロースエーテル含有カプセル及びその製造方法
WO2005065526A1 (ja) * 2004-01-07 2005-07-21 Olympus Corporation カプセル型医療装置、医療用カプセル筐体とその製造方法
PE20060003A1 (es) * 2004-03-12 2006-03-01 Smithkline Beecham Plc Formulacion farmaceutica polimerica para moldear por inyeccion
JPWO2005113010A1 (ja) * 2004-05-24 2008-07-31 クオリカプス株式会社 表面改質および溶解性が改善された硬カプセル
CA2469339A1 (en) * 2004-06-07 2005-12-07 Bernard Charles Sherman Sustained release propafenone hydrochloride capsules
TWI389688B (zh) * 2004-06-08 2013-03-21 Vertex Pharma Vx-950之形態與調配物及其製備方法與用途
EP1771158A4 (en) * 2004-07-02 2008-03-12 Advancis Pharmaceutical Corp TABLET FOR PULSED DELIVERY
US20060049154A1 (en) * 2004-09-09 2006-03-09 Clifford George M Jr System and method for bonding camera components after adjustment
CA2588418C (en) * 2004-11-19 2015-06-02 Smithkline Beecham Corporation Pharmaceutical product providing a plurality of components
JP2009505966A (ja) * 2005-08-02 2009-02-12 バーテックス ファーマシューティカルズ インコーポレイテッド セリンプロテアーゼのインヒビター
US7964624B1 (en) * 2005-08-26 2011-06-21 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases
AR055395A1 (es) * 2005-08-26 2007-08-22 Vertex Pharma Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
ES2549080T3 (es) 2005-11-18 2015-10-22 Glaxo Group Limited Máquina y método para el ensamblaje de productos farmacéuticos y productos similares a farmacéuticos
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
CA2635566A1 (en) * 2005-12-30 2007-07-12 Accu-Break Technologies, Inc. Adhesively bonded dosage form
JP5436864B2 (ja) 2006-02-27 2014-03-05 バーテックス ファーマシューティカルズ インコーポレイテッド Vx−950を含む共結晶体およびそれを含む医薬組成物
CA2646229A1 (en) 2006-03-16 2007-09-27 Vertex Pharmaceuticals Incorporated Deuterated hepatitis c protease inhibitors
WO2007109604A2 (en) * 2006-03-20 2007-09-27 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
WO2008028193A2 (en) * 2006-09-01 2008-03-06 Pharmion Corporation Colon-targeted oral formulations of cytidine analogs
US20100074926A1 (en) * 2006-12-05 2010-03-25 Universita' Degli Studi Di Parma Modules, new assemblage kits and new assembles for the controlled release of substances
JP2010519330A (ja) * 2007-02-27 2010-06-03 バーテックス ファーマシューティカルズ インコーポレイテッド 共結晶体およびそれを含む医薬組成物
JP2010519329A (ja) * 2007-02-27 2010-06-03 バーテックス ファーマシューティカルズ インコーポレイテッド セリンプロテアーゼ阻害剤
WO2008113368A1 (en) * 2007-03-21 2008-09-25 Kariem Ezzat Mahmoud A gelatin capsule with extra cap for combined therapies
WO2008136016A1 (en) * 2007-05-08 2008-11-13 Medreich Limited A stable controlled release oral solid dosage form composition and a process thereof
US8329220B2 (en) 2007-08-24 2012-12-11 Aegis Therapeutics, Llc Controlled release formulations
NZ583699A (en) * 2007-08-30 2012-04-27 Vertex Pharma Co-crystals of vx-950 (telaprevir) other components and pharmaceutical compositions comprising the same
EP2537506A1 (en) 2007-10-15 2012-12-26 Capsugel Belgium NV Linkers for multipart dosage forms for release of one or more parmaceutical compositions, and the resulting dosage forms
JP5190515B2 (ja) 2007-10-15 2013-04-24 カプスゲル・ベルギウム・ナムローゼ・フェンノートシャップ 充填リンカーを製造する方法および装置
US8454992B2 (en) 2007-10-15 2013-06-04 Capsugel Belgium Nv Paneled capsule shells for release of pharmaceutical compositions
EP2219624A2 (en) * 2007-11-08 2010-08-25 Glaxo Group Limited Pharmaceutical formulations
EP3782611B1 (en) 2008-05-15 2022-07-06 Celgene Corporation Oral formulations of cytidine analogs and methods of use thereof
WO2009150228A2 (en) * 2008-06-13 2009-12-17 Glaxo Group Limited Pharmaceutical formulations
WO2009154396A2 (en) * 2008-06-17 2009-12-23 Pharmapex Co., Ltd. Sustained releasing preparation comprising a crude drug extract for preventing moisturization and controlled release
SG184523A1 (en) 2010-05-10 2012-11-29 Euro Celtique Sa Pharmaceutical compositions comprising hydromorphone and naloxone
CA2798884C (en) 2010-05-10 2016-09-13 Euro-Celtique S.A. Manufacturing of active-free granules and tablets comprising the same
WO2011141490A1 (en) 2010-05-10 2011-11-17 Euro-Celtique S.A. Combination of active loaded granules with additional actives
CN103601628B (zh) 2010-11-12 2015-11-18 深圳市有为化学技术有限公司 对位或间位官能团化芳香酮类化合物、其制备方法及其光聚合引发剂
EP2550863A1 (de) * 2011-07-27 2013-01-30 Bayer Intellectual Property GmbH Aktivstoffhaltige Partikel auf Polyacrylat-Basis
EP2750666B1 (en) * 2011-08-30 2017-10-04 Universiteit Gent Multi-layered release formulation
CN103874727B (zh) * 2011-10-12 2016-05-11 陶氏环球技术有限责任公司 注塑的剂型
CN104379111A (zh) * 2011-12-16 2015-02-25 维玛科合资有限公司 阴道药物递送器具和制造方法
KR101378069B1 (ko) * 2012-05-17 2014-03-27 박정배 황칠나무 추출액을 이용한 막걸리 및 그의 제조방법
WO2014048783A1 (en) * 2012-09-27 2014-04-03 Basf Se A storage-stable dust-free homogeneous particulate formulation comprising at least one water-soluble vitamin e-derivative and at least one hydrophilic polymer
JP6232135B2 (ja) 2013-11-13 2017-11-15 ユーロ−セルティーク エス.エイ. 疼痛およびオピオイドによる腸機能障害症候群の治療のためのヒドロモルホンおよびナロキソン
CN103937037B (zh) * 2014-04-28 2016-09-21 北京崇尚科技开发有限公司 用于制备空心胶囊的变性淀粉胶及其淀粉基质空心胶囊
EP3164117B1 (en) 2014-07-03 2023-09-06 SpecGx LLC Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides
EP3182996B1 (en) 2014-08-22 2022-12-28 Celgene Corporation Methods of treating multiple myeloma with immunomodulatory compounds in combination with antibodies
CA3023278C (en) * 2016-05-05 2019-04-30 Triastek, Inc. Controlled release dosage form
US10456975B2 (en) 2016-07-15 2019-10-29 Multiply Labs Inc. Multi-compartment capsule
CN106177971A (zh) * 2016-07-20 2016-12-07 贵州理工学院 含有薄荷醇的土豆淀粉胶囊壳
JP6742197B2 (ja) * 2016-08-29 2020-08-19 信越化学工業株式会社 ヒプロメロースフタル酸エステルの製造方法
BR112020000011A2 (pt) 2017-07-11 2020-07-21 Qualicaps Co., Ltd. cápsula dura entérica
JP2020536075A (ja) * 2017-10-02 2020-12-10 ノバルティス アーゲー 医薬担体の設計
EP3691615A1 (en) * 2017-10-02 2020-08-12 Novartis AG Method for producing a pharmaceutical carrier
EP3811976B1 (en) * 2018-06-22 2024-02-21 Qualicaps Co., Ltd. Enteric hard capsule
WO2020068510A1 (en) 2018-09-25 2020-04-02 SpecGx LLC Abuse deterrent immediate release capsule dosage forms
EP3633215B1 (en) 2018-10-02 2021-07-07 Newfrey LLC Self-piercing rivet
WO2020212829A1 (en) * 2019-04-17 2020-10-22 Amruth Gowda Doddaveerappa Multi-component pharmaceutical single dosage forms and methods employed thereof
CA3203975A1 (en) 2020-12-03 2022-06-09 Battelle Memorial Institute Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery
US12031128B2 (en) 2021-04-07 2024-07-09 Battelle Memorial Institute Rapid design, build, test, and learn technologies for identifying and using non-viral carriers
WO2023145869A1 (ja) * 2022-01-31 2023-08-03 住友精化株式会社 製剤用組成物の製造方法及び製剤の製造方法
WO2023145871A1 (ja) * 2022-01-31 2023-08-03 住友精化株式会社 製剤用組成物の製造方法及び製剤の製造方法

Family Cites Families (196)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US87049A (en) * 1869-02-16 Improved cheese-cutter
US148518A (en) * 1874-03-10 Improvement in mail-bag holders
US108492A (en) * 1870-10-18 Improvement in rufflers for sewing-machines
US148514A (en) * 1874-03-10 Improvement in band-pulleys
US110723A (en) * 1871-01-03 Improvement in car-replacers
US160042A (en) * 1875-02-23 Improvement in soles for boots and shoes
US177496A (en) * 1876-05-16 gafney
US260814A (en) * 1882-07-11 Combined seeder and cultivator
US110721A (en) * 1871-01-03 Meat-cutters
US104501A (en) * 1870-06-21 Steam-radiator
NL156848B (nl) 1950-10-26 Philips Nv Inrichting voor het opwekken van tonen van een toonladder, alsmede muziekinstrument voorzien van een dergelijke inrichting.
US3186910A (en) 1962-03-08 1965-06-01 Jacob A Glassman Method for producing peroral capsules
US3228789A (en) 1962-10-22 1966-01-11 Jacob A Glassman Peroral capsules and tablets and the method for making same
US3278520A (en) * 1963-02-08 1966-10-11 Hercules Inc Hydroxypropyl cellulose and process
US3394983A (en) * 1963-06-14 1968-07-30 American Cyanamid Co Dip-dyeing capsules
FR1454013A (fr) 1965-08-18 1966-07-22 Pluripharm Mode de présentation de deux médicaments associés
US3399803A (en) * 1966-10-11 1968-09-03 Parke Davis & Co Self-locking medicament capsule
CA944689A (en) * 1970-07-28 1974-04-02 Claude Rene Capsules en matieres plastiques et leurs procedes de fabrication
US3779942A (en) * 1970-12-04 1973-12-18 Minnesota Mining & Mfg Capsules and process for forming capsules
US3723312A (en) * 1970-12-18 1973-03-27 Ppg Industries Inc Combined stain retardant and separator interleaving material for glass sheets
DE2428397C3 (de) 1974-06-12 1978-05-18 Scherer Hartkapsel Gmbh, 6930 Eberbach Zweiteilige Kapsel aus Hartgelatine
NL7610038A (en) 1976-09-09 1978-03-13 Tapanahony N V Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively
DE2722822C2 (de) * 1977-05-20 1984-11-08 Capsugel AG, Basel Verfahren zum Herstellen einer zum Aufnehmen eines viskosen Stoffes, insbesondere eines flüssigen Arzneimittels, geeigneten Steckkapsel
US4250097A (en) * 1978-03-08 1981-02-10 Syntex (U.S.A.) Inc. Compositions for and a method of preventing diabetic complications
FI63335B (fi) * 1979-02-02 1983-02-28 Orion Yhtymae Oy Foerfarande foer framstaellning av tabletter med foerdroejd loslighet av effektaemne
US4281763A (en) * 1979-10-31 1981-08-04 Pace Joseph A Two-piece hardshell, soluble and digestible liquid containing gelatin capsule
US4766728A (en) * 1983-03-28 1988-08-30 Rexa Corporation Flow matching valve and hydraulic system employing same
US4417591A (en) 1980-12-31 1983-11-29 Braintech, Inc. Apparatus and method for topographic display of multichannel EEG data
USRE34390E (en) * 1980-12-31 1993-09-28 Nicolet Instrument Corporation Apparatus and method for topographic display of multichannel EEG data
US4498080A (en) * 1980-12-31 1985-02-05 Braintech, Inc. Apparatus and method for topographic display of multichannel data
EP0091908A1 (en) 1981-10-21 1983-10-26 SMITH, Charles E A method and composition for substrate coating
JPS58134019A (ja) 1982-02-05 1983-08-10 Ono Pharmaceut Co Ltd プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法
US4790881A (en) 1982-03-26 1988-12-13 Warner-Lambert Company Molded hydrophilic polymer
US4655840A (en) 1982-03-26 1987-04-07 Warner-Lambert Company Hydrophilic polymer compositions for injection molding
EG16028A (en) 1982-03-26 1986-12-30 Warner Lambert Co Apparatus and method for molding capsules
EG16027A (en) * 1982-03-26 1986-12-30 Warner Lambert Co Hydrophilic polymer composition for injection molding
FR2524311A1 (fr) 1982-04-05 1983-10-07 Azalbert Gilles Gelule compartimentee aux fins d'ingestions simultanees a effets differes
US4550238A (en) * 1982-11-05 1985-10-29 Warner-Lambert Company Apparatus and method for sealing capsules
USD285837S (en) * 1982-12-20 1986-09-23 Warner-Lambert Company Pharmaceutical capsule
US4487327A (en) 1982-12-21 1984-12-11 Grayson Robert E Locking capsule
US4625513A (en) 1983-03-28 1986-12-02 Rexa Corporation Controlled flow hydraulic system
US4696163A (en) * 1983-03-28 1987-09-29 Rexa Corporation Control valve and hydraulic system employing same
US4557180A (en) 1983-03-28 1985-12-10 Rexa Corporation Control valve and hydraulic system employing same
US4543138A (en) * 1983-07-07 1985-09-24 Eli Lilly & Company Capsule-sealing method and apparatus
US4564363A (en) * 1983-07-13 1986-01-14 Smithkline Beckman Corporation Delayed action assembly
US4576284A (en) 1983-12-02 1986-03-18 Warner-Lambert Company Closing of filled capsules
US4738724A (en) 1983-11-04 1988-04-19 Warner-Lambert Company Method for forming pharmaceutical capsules from starch compositions
CH661878A5 (de) 1983-11-04 1987-08-31 Warner Lambert Co Kapsel-dosierungsformen.
US4738817A (en) * 1983-11-17 1988-04-19 Warner-Lambert Company Method for forming pharmaceutical capsules from hydrophilic polymers
US4673438A (en) * 1984-02-13 1987-06-16 Warner-Lambert Company Polymer composition for injection molding
DE3581428D1 (de) 1984-06-13 1991-02-28 Roehm Gmbh Verfahren zum ueberziehen von arzneiformen.
US5082655A (en) 1984-07-23 1992-01-21 Zetachron, Inc. Pharmaceutical composition for drugs subject to supercooling
US4629621A (en) 1984-07-23 1986-12-16 Zetachron, Inc. Erodible matrix for sustained release bioactive composition
US4678516A (en) 1984-10-09 1987-07-07 The Dow Chemical Company Sustained release dosage form based on highly plasticized cellulose ether gels
DE3438291A1 (de) * 1984-10-19 1986-04-24 Röhm GmbH, 6100 Darmstadt Verfahren zur herstellung einer waessrigen ueberzugsmitteldispersion und ihre verwendung zum ueberziehen von arzneimitteln
GB2172569A (en) 1985-03-21 1986-09-24 Warner Lambert Co Improved capsule construction
WO1986004501A1 (en) 1985-01-31 1986-08-14 Fujisawa Pharmaceutical Co., Ltd. Soft multi-chamber capsule and method of and apparatus for manufacturing same
DE3524963A1 (de) 1985-07-12 1987-01-22 Scherer R P Hartkapsel Gmbh Zweiteilige steckkapsel
EP0228067B1 (en) 1985-12-26 1991-09-18 Taisho Pharmaceutical Co. Ltd Seamless soft capsule
US4764378A (en) 1986-02-10 1988-08-16 Zetachron, Inc. Buccal drug dosage form
US4928840A (en) * 1986-02-25 1990-05-29 American Home Products Corporation Tamper proof encapsulated medicaments
CH674800A5 (pt) 1986-03-12 1990-07-31 Warner Lambert Co
DE3612212A1 (de) * 1986-04-11 1987-10-15 Basf Ag Verfahren zur herstellung von festen pharmazeutischen formen
US4793493A (en) 1986-09-18 1988-12-27 Makiej Jr Walter J Multidose capsules
US4936461A (en) * 1986-09-18 1990-06-26 Makiej Jr Walter J Multidose capsules
DE3631826A1 (de) * 1986-09-19 1988-03-31 Roehm Gmbh Herstellung eines methylmethacrylat-copolymerisats
US5074426A (en) * 1986-11-13 1991-12-24 Warner-Lambert Company Dividable capsule
JPH0787207B2 (ja) * 1986-11-13 1995-09-20 日本電信電話株式会社 集積回路試験装置
KR890003520Y1 (ko) 1986-12-20 1989-05-27 주식회사 서흥캅셀 의약용 캅셀
US4724019A (en) * 1987-03-20 1988-02-09 Warner-Lambert Company Method and apparatus for sealing capsules
DE3720757A1 (de) * 1987-06-24 1989-01-05 Bayer Ag Dhp-manteltablette
US5236689A (en) * 1987-06-25 1993-08-17 Alza Corporation Multi-unit delivery system
US4795644A (en) * 1987-08-03 1989-01-03 Merck & Co., Inc. Device for pH independent release of drugs through the Donnan-like influence of charged insoluble resins
DE3727894A1 (de) 1987-08-21 1989-03-02 Stephan Dieter Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge
DE3735260A1 (de) * 1987-10-17 1989-04-27 Bosch Gmbh Robert Verschliessvorrichtung fuer zweiteilige kapseln
ES2052911T3 (es) * 1988-05-04 1994-07-16 Smith Kline French Lab Tableta masticable.
DE3830013C2 (de) * 1988-09-03 1996-10-17 Bosch Gmbh Robert Füll- und Schließmaschine für zweiteilige Kapseln
US4944906A (en) 1988-10-11 1990-07-31 Spirex Corporation Methods of injection molding and extruding wet hygroscopic ionomers
US5244668A (en) 1988-10-14 1993-09-14 Zetachron, Inc. Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith
US5139790A (en) * 1988-10-14 1992-08-18 Zetachron, Inc. Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith
US5135752A (en) * 1988-10-14 1992-08-04 Zetachron, Inc. Buccal dosage form
US5004601A (en) 1988-10-14 1991-04-02 Zetachron, Inc. Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith
US4936074A (en) * 1988-11-17 1990-06-26 D. M. Graham Laboratories, Inc. Process for preparing solid encapsulated medicament
US5728088A (en) * 1988-12-13 1998-03-17 Alza Corporation Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
DE3902653A1 (de) * 1989-01-30 1990-08-02 Roehm Gmbh Elastomere acrylharze
US6200600B1 (en) * 1989-02-16 2001-03-13 Btg International Limited Controlled delay release device
DE3907019A1 (de) * 1989-03-04 1990-09-06 Roehm Gmbh Thermoplastisch verarbeitbare loesungsmittelbestaendige kunststoffmischungen
WO1990012567A1 (en) 1989-04-21 1990-11-01 Moskovsky Avtomobilestroitelny Institut (Vtuz-Zil) Device for controlled dosing of active substances into an operative medium
JPH0729926B2 (ja) * 1989-07-25 1995-04-05 大塚製薬株式会社 易吸収性製剤用組成物
DK469989D0 (da) * 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
US5456919A (en) * 1989-12-29 1995-10-10 Bristol-Myers Squibb Company Capsule and caplet combination
DE4002904A1 (de) * 1990-02-01 1991-08-08 Roehm Gmbh Verfahren zum imidieren eines methacrylester-polymerisats
KR0183058B1 (ko) * 1991-01-30 1999-05-01 에드워드 엘.만델 지연된 약물 전달을 위한 삼투장치
US5976571A (en) * 1991-01-31 1999-11-02 Port Systems, L.L.C. Method for making a multi-stage drug delivery system
US5674530A (en) * 1991-01-31 1997-10-07 Port Systems, L.L.C. Method for making a multi-stage drug delivery system
US5387421A (en) * 1991-01-31 1995-02-07 Tsrl, Inc. Multi stage drug delivery system
CA2068402C (en) * 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
DE4121652A1 (de) 1991-06-29 1993-01-07 Roehm Gmbh Schlagzaeh-modifizierungsmittel
US5225202A (en) * 1991-09-30 1993-07-06 E. R. Squibb & Sons, Inc. Enteric coated pharmaceutical compositions
DE4138513A1 (de) 1991-11-23 1993-05-27 Basf Ag Feste pharmazeutische retardform
JP2512258B2 (ja) * 1992-03-11 1996-07-03 松下電器産業株式会社 シ―ト給送装置
GB9223144D0 (en) * 1992-11-05 1992-12-16 Scherer Corp R P Controlled release device
GB9223172D0 (en) * 1992-11-05 1992-12-16 Scherer Corp R P Capsule construction
US5312008A (en) * 1993-05-26 1994-05-17 Davis Bradford L Personal time capsule
EP0804174A4 (en) * 1993-07-21 1998-09-09 Univ Kentucky Res Found MULTI-CHAMBER HARD CAPSULES WITH CONTROLLED DELIVERY CHARACTERISTICS
US5443461A (en) * 1993-08-31 1995-08-22 Alza Corporation Segmented device for simultaneous delivery of multiple beneficial agents
GB9325445D0 (en) 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
DE4402666A1 (de) * 1994-01-29 1995-08-03 Roehm Gmbh Verfahren zum kurzzeitigen Behandeln einer Kunststoffschmelze mit einem flüssigen Behandlungsmittel und dabei hergestellter thermoplastischer Kunststoff
DE4413350A1 (de) 1994-04-18 1995-10-19 Basf Ag Retard-Matrixpellets und Verfahren zu ihrer Herstellung
ES2188657T3 (es) * 1994-04-22 2003-07-01 Yamanouchi Pharma Co Ltd Sistema para la liberacion especifica en el colon de un farmaco.
DE19509807A1 (de) * 1995-03-21 1996-09-26 Basf Ag Verfahren zur Herstellung von Wirkstoffzubereitungen in Form einer festen Lösung des Wirkstoffs in einer Polymermatrix sowie mit diesem Verfahren hergestellte Wirkstoffzubereitungen
DE9414065U1 (de) 1994-08-31 1994-11-03 Röhm GmbH & Co. KG, 64293 Darmstadt Thermoplastischer Kunststoff für darmsaftlösliche Arznei-Umhüllungen
DE9414066U1 (de) * 1994-08-31 1994-11-03 Röhm GmbH & Co. KG, 64293 Darmstadt Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform
US5593696A (en) * 1994-11-21 1997-01-14 Mcneil-Ppc, Inc. Stabilized composition of famotidine and sucralfate for treatment of gastrointestinal disorders
US6245350B1 (en) * 1994-12-16 2001-06-12 Warner-Lambert Company Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process
US5529783A (en) * 1994-12-19 1996-06-25 Mcneil-Ppc, Inc. Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan
DE4445498A1 (de) * 1994-12-20 1996-06-27 Roehm Gmbh Universell verträgliche Pigmentdispergatoren
US5948422A (en) * 1995-02-08 1999-09-07 Yamanouchi Europe B.V. Oral dosage-forms containing a β-lactam antibiotic
DE19504832A1 (de) 1995-02-14 1996-08-22 Basf Ag Feste Wirkstoff-Zubereitungen
DE19504831A1 (de) 1995-02-14 1996-09-05 Basf Ag Feste Wirkstoffzubereitungen enthaltend Hydroxypropylcellulose
DE29502547U1 (de) * 1995-02-16 1995-03-30 Röhm GmbH, 64293 Darmstadt Thermoplastisches Überzugs- und Bindemittel für Arzneiformen
DE19509805A1 (de) 1995-03-21 1996-09-26 Basf Ag Transparente, schnell freisetzende Zubereitungen von nichtsteroidalen Analgetica
SG80553A1 (en) * 1995-07-20 2001-05-22 Tanabe Seiyaku Co Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
DE19531277A1 (de) 1995-08-25 1997-02-27 Basf Ag Verwendung von Lipiden als Hilfsmittel bei der Herstellung von festen Arzneiformen nach dem Schmelzextrusionsverfahren
US5769267A (en) * 1995-11-09 1998-06-23 Warner-Lambert Company Container
JP3220373B2 (ja) * 1995-11-28 2001-10-22 バイエル薬品株式会社 持続性ニフエジピン製剤
DE19544562B4 (de) 1995-11-30 2004-05-27 Röhm GmbH & Co. KG Verfahren zur Herstellung von Poly(meth)acrylimiden mit bei thermischer Belastung verbesserter Farbstabilität und daraus erhältliche Formkörper
FR2747042B1 (fr) * 1996-04-05 1998-06-05 Besins Iscovesco Lab Medicament a base de progesterone et d'oestradiol
WO1998030209A1 (en) * 1997-01-06 1998-07-16 Pfizer Pharmaceuticals Inc. Rapidly releasing and taste-masking pharmaceutical dosage form
DE19701441C2 (de) * 1997-01-17 1998-11-05 Roehm Gmbh Verfahren zur Herstellung farbneutraler Polymethylmethacrylat-Formmassen
DE19718597C1 (de) * 1997-05-02 1999-01-07 Roehm Gmbh Zweistufiges Verfahren zur Entwässerung von Kunststoffdispersionen
US6046177A (en) * 1997-05-05 2000-04-04 Cydex, Inc. Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations
DE19721467A1 (de) 1997-05-22 1998-11-26 Basf Ag Verfahren zur Herstellung kleinteiliger Zubereitungen biologisch aktiver Stoffe
DE19733505A1 (de) 1997-08-01 1999-02-04 Knoll Ag Schnell wirksames Analgeticum
DE19753299A1 (de) 1997-12-01 1999-06-02 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
DE19753297A1 (de) 1997-12-01 1999-06-02 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
DE19753298A1 (de) 1997-12-01 1999-06-02 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
DE19753300A1 (de) 1997-12-01 1999-06-02 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
DE19800927A1 (de) 1998-01-13 1999-07-15 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
GB9801363D0 (en) * 1998-01-22 1998-03-18 Danbiosyst Uk Novel dosage form
US5931776A (en) * 1998-03-09 1999-08-03 Dotolo Research Corporation Speculum having dissolvable tip
DE19812688A1 (de) 1998-03-23 1999-09-30 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
DE19821788C1 (de) * 1998-05-15 1999-12-02 Sanol Arznei Schwarz Gmbh Transdermales Therapeutisches System (TTS) Pergolid enthaltend
DE19918435A1 (de) * 1998-07-23 2000-01-27 Roehm Gmbh Überzugs- und Bindemittel für orale oder dermale Arzneiformen
DE19835346A1 (de) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
DE19843904A1 (de) * 1998-09-24 2000-03-30 Basf Ag Feste Dosierungsform mit polymerem Bindemittel
AU9664498A (en) * 1998-09-24 2000-04-10 Procter & Gamble Company, The Chewable compositions containing dextromethorphan
US6139875A (en) * 1998-09-29 2000-10-31 Eastman Chemical Company Aqueous enteric coating composition and low gastric permeability enteric coating
ATE424191T1 (de) * 1999-02-04 2009-03-15 Abbott Lab Ph-unabhängige pharmazeutische formulierungen mit verlängerter freisetzung
IT1316684B1 (it) * 1999-03-13 2003-04-24 Bosch Gmbh Robert Supporto delle parti di capsule in una macchina di caricamento e dichiusura per capsule in due parti
US6248807B1 (en) * 1999-03-15 2001-06-19 Fina Technology, Inc. Method for the preparation of core-shell morphologies from polybutadiene-polystyrene graft copolymers
DE19914605A1 (de) * 1999-03-30 2000-10-05 Roehm Gmbh Polyalkylmethacrylat-Plastisole mit verbesserten Fließeigenschaften
WO2000059479A1 (en) * 1999-04-06 2000-10-12 Pharmaquest Ltd. Pharmaceutical dosage form for pulsatile delivery of methylphenidate
EP1204410B1 (en) * 1999-07-30 2012-09-12 Capsugel Belgium NV Multi-component pharmaceutical dosage form
CA2391613C (en) * 1999-11-17 2009-01-20 Reckitt Benckiser (Uk) Limited Injection-moulded water-soluble container
DE19958007A1 (de) * 1999-12-02 2001-06-07 Roehm Gmbh Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen
DE19960494A1 (de) * 1999-12-15 2001-06-21 Knoll Ag Vorrichtung und Verfahren zum Herstellen von festen wirkstoffhaltigen Formen
DE19961334A1 (de) * 1999-12-17 2001-06-21 Roehm Gmbh Spritzgußverfahren für neutrale und säuregruppenhaltige (Meth)acrylat-Copolymere
GB0001621D0 (en) * 2000-01-26 2000-03-15 Astrazeneca Ab Pharmaceutical compositions
WO2001070201A1 (fr) 2000-03-23 2001-09-27 Shionogi & Co., Ltd. Preparations granulaires gastro-resistantes constituees de medicaments peu hydrosolubles qui sont caracterises en ce qu'ils contiennent un composant hydroresistant
US6551617B1 (en) * 2000-04-20 2003-04-22 Bristol-Myers Squibb Company Taste masking coating composition
DE10043868A1 (de) * 2000-09-04 2002-04-04 Roehm Gmbh PMMA Formmassen mit verbesserter Schlagzähigkeit
DE10054051A1 (de) * 2000-10-31 2002-05-29 Roehm Gmbh PMMA-Formmasse mit verbesserter Kälteschlagzähigkeit
US7883721B2 (en) * 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US7842308B2 (en) * 2001-01-30 2010-11-30 Smithkline Beecham Limited Pharmaceutical formulation
DE10127134A1 (de) * 2001-06-05 2002-12-12 Roehm Gmbh verfahren zur Herstellung von Formkörpern aus (Meth)acrylat-Copolymeren mittels Spritzguß
US6949154B2 (en) * 2001-07-28 2005-09-27 Boehringer Ingelheim Pharma Kg Method and apparatus for sealing medicinal capsules
US7217381B2 (en) * 2001-09-28 2007-05-15 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
JP2003171277A (ja) 2001-12-07 2003-06-17 Wyeth Lederle Japan Ltd 薬物放出時間制御型固形製剤
RU2004123792A (ru) * 2002-01-04 2005-04-10 Ивэкс Рисеч, Инк. (Us) Устройство доставки препарата для пролонгированной доставки глипизита
USD481456S1 (en) * 2002-01-30 2003-10-28 Smithkline Beecham P.L.C. Capsule
DE10204890A1 (de) * 2002-02-06 2003-08-14 Roehm Gmbh Schlagzähe Formmasse und Formkörper
US20030194429A1 (en) 2002-04-10 2003-10-16 Miller Frederick H. Multi-phase, multi-compartment capsular delivery apparatus for therapeutic compositions and methods for using same
US7670612B2 (en) * 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
TWI336260B (en) * 2002-07-25 2011-01-21 Glaxo Group Ltd Dosage form suitable for retaining drug substance
DE10243062A1 (de) 2002-09-16 2004-03-25 Röhm GmbH & Co. KG Heißwasserwechseltestbeständiges Sanitärmaterial aus PMMA-Formmasse oder schlagzäher PMMA-Formmasse
DE10260065A1 (de) * 2002-12-19 2004-07-01 Röhm GmbH & Co. KG Kern-Schale-Teilchen zur Schlagzähmodifizierung von Poly(meth)acrylat-Formmassen
DE10260089A1 (de) * 2002-12-19 2004-07-01 Röhm GmbH & Co. KG Verfahren zur Herstellung von wässrigen Dispersionen
DE10329938A1 (de) * 2003-07-02 2005-03-17 Röhm GmbH & Co. KG Kunststoffkörper mit mikrostrukturierter Oberfläche
DE10349144A1 (de) * 2003-10-17 2005-05-12 Roehm Gmbh Polymermischung für mattierte Spritzgußteile
DE10349142A1 (de) * 2003-10-17 2005-05-12 Roehm Gmbh Polymermischung sowie deren Verwendung für Spritzgußteile
DE10351535A1 (de) * 2003-11-03 2005-06-09 Röhm GmbH & Co. KG Mehrschichtfolie aus (Meth)acrylatcopolymer und Polycarbonat
DE10354379A1 (de) * 2003-11-20 2005-06-23 Röhm GmbH & Co. KG Formmasse, enthaltend ein Mattierungsmittel
US20050142203A1 (en) * 2003-12-30 2005-06-30 Grant Heinicke Oral dosage formulations of active pharmaceutical ingredients and methods of preparing the same
US20070160677A1 (en) 2004-01-16 2007-07-12 Pillai Raviraj S Encapsulation of lipid-based formulations in enteric polymers
DE102004022540A1 (de) * 2004-05-05 2005-12-08 Röhm GmbH & Co. KG Formmasse für Formkörper mit hoher Witterungsbeständigkeit
JP4354360B2 (ja) * 2004-07-26 2009-10-28 Okiセミコンダクタ株式会社 降圧電源装置
DE102004045296A1 (de) 2004-09-16 2006-03-23 Röhm GmbH & Co. KG Verwendung von Polyalkyl (meth) acrylat-Perlpolymerisaten und Formmasse zur Herstellung von extrudierten Formteilen mit mattierter Oberfläche
JP2008535837A (ja) 2005-04-06 2008-09-04 マリンクロッド・インコーポレイテッド マトリックスをベースとするパルス放出製剤
US20080014257A1 (en) * 2006-07-14 2008-01-17 Par Pharmaceutical, Inc. Oral dosage forms
EP2537506A1 (en) * 2007-10-15 2012-12-26 Capsugel Belgium NV Linkers for multipart dosage forms for release of one or more parmaceutical compositions, and the resulting dosage forms
JP5190515B2 (ja) * 2007-10-15 2013-04-24 カプスゲル・ベルギウム・ナムローゼ・フェンノートシャップ 充填リンカーを製造する方法および装置
WO2009050189A2 (en) * 2007-10-15 2009-04-23 Glaxo Group Limited Multipart capsule for staged release of one or more substances
US8454992B2 (en) * 2007-10-15 2013-06-04 Capsugel Belgium Nv Paneled capsule shells for release of pharmaceutical compositions
EP2219624A2 (en) * 2007-11-08 2010-08-25 Glaxo Group Limited Pharmaceutical formulations

Also Published As

Publication number Publication date
EP1389093A2 (en) 2004-02-18
EP1363607A4 (en) 2009-03-11
EP2366384A3 (en) 2012-02-22
EP2366384B1 (en) 2013-04-03
PL208634B1 (pl) 2011-05-31
CN1529588A (zh) 2004-09-15
CZ20031980A3 (en) 2004-03-17
CN1529588B (zh) 2011-08-10
KR20030072611A (ko) 2003-09-15
KR20030072610A (ko) 2003-09-15
JP2012229224A (ja) 2012-11-22
BR0206627A (pt) 2004-02-25
CN1489456A (zh) 2004-04-14
JP2004522746A (ja) 2004-07-29
KR101128228B1 (ko) 2012-03-26
WO2002060385A2 (en) 2002-08-08
US20110300212A1 (en) 2011-12-08
CN1489456B (zh) 2011-02-23
PL368547A1 (en) 2005-04-04
EP2366382A2 (en) 2011-09-21
CN102198114A (zh) 2011-09-28
NO20033143L (no) 2003-09-19
KR20100006587A (ko) 2010-01-19
US8367101B2 (en) 2013-02-05
EP2366382B1 (en) 2015-05-13
NZ544503A (en) 2008-05-30
ZA200305045B (en) 2004-04-28
NZ544259A (en) 2008-01-31
EP1363607B1 (en) 2012-11-21
PL368554A1 (en) 2005-04-04
HUP0302876A3 (en) 2005-05-30
TWI257871B (en) 2006-07-11
MXPA03006775A (es) 2003-10-24
AU2009212847B2 (en) 2012-04-26
IL156716A (en) 2009-07-20
MXPA03006884A (es) 2003-11-13
EP1363607A2 (en) 2003-11-26
EP2366382A3 (en) 2012-02-15
JP2009173668A (ja) 2009-08-06
HUP0302857A2 (hu) 2003-12-29
WO2002060384A3 (en) 2003-05-30
WO2002060384A2 (en) 2002-08-08
IL156783A0 (en) 2004-05-12
TWI322015B (en) 2010-03-21
CZ20032003A3 (en) 2004-04-14
KR20120004558A (ko) 2012-01-12
NO20033143D0 (no) 2003-07-09
NO20033384D0 (no) 2003-07-29
AU2009212847A1 (en) 2009-09-24
HUP0302876A2 (hu) 2003-12-29
EP1389093A4 (en) 2009-03-11
EP2366384A2 (en) 2011-09-21
GB0102342D0 (en) 2001-03-14
NO20033384L (no) 2003-09-25
JP2004524300A (ja) 2004-08-12
AU2002242024B2 (en) 2006-01-12
CA2436416C (en) 2012-07-17
ZA200304810B (en) 2004-04-23
AU2005248931A1 (en) 2006-01-19
AR032525A1 (es) 2003-11-12
US20030049311A1 (en) 2003-03-13
EP2366383A3 (en) 2012-02-22
AR032524A1 (es) 2003-11-12
WO2002060385A3 (en) 2003-11-27
CA2436416A1 (en) 2002-08-08
IL156716A0 (en) 2004-01-04
US20030068369A1 (en) 2003-04-10
EP2366383A2 (en) 2011-09-21
ES2399838T3 (es) 2013-04-03
CA2437350A1 (en) 2002-08-08
HUP0302857A3 (en) 2005-05-30

Similar Documents

Publication Publication Date Title
BR0206752A (pt) Formulação farmacêutica
BRPI0508342A (pt) formulações farmacêuticas
BR0012869A (pt) Forma de dosagem farmacêutica de componentes múltiplos
BRPI0412678A (pt) formulações farmacêuticas
MX2010005092A (es) Formulaciones farmaceuticas.
AR110986A2 (es) Composiciones de ecteinascidina, formulaciones liofilizadas, método de preparación y uso
AR025959A1 (es) DERIVADOS DE TER.-BUTIL-(7-METIL-IMIDAZO[1,2,a]PIRIDIN-3-IL)-AMINA, PROCEDIMIENTO PARA SU PREPARACION, MEDICAMENTOS QUE LOS CONTIENEN, SU USO PARA LAPREPARACION DE UN MEDICAMENTO PARA LA INHIBICION DE NO-SINTASA Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN
DOP2013000085A (es) Formulacion de capsula
BR0107564A (pt) Composição de gliburida
ES2206081T1 (es) Procedimiento para preparar composiciones farmaceuticas para uso con formulaciones de gelatina blanda.
BRPI0413112A (pt) compostos de indol-6 sulfonamida, processos de obtenção de seus derivados, seus medicamentos e usos como moduladores de 5-ht-6
PA8594801A1 (es) Formulaciones farmaceuticas liquidas de palanosetron
BR0211198A (pt) Composições farmacêuticas e seu uso
AR098745A2 (es) Composición, kit y uso de compuestos quimioterapéuticos
BRPI0413062A (pt) compostos de sulfonamida, processos de obtenção de seus derivados, seus medicamentos e usos
BRPI0413110A (pt) derivados de indo-5-il sulfonamida, sua preparação e uso de 5-ht-6 como moduladores
PE20030830A1 (es) Ambroxol para el tratamiento de estados dolorosos en la cavidad bucal y faringea
CL2004001843A1 (es) Combinacion de (a) al menos un derivado 2,5-dihidrobencenosulfonico, como el dobeilato calcico, etamsilato y persilato, y (b) al menos un modulador de los canales de potasio, composicion farmaceutica que la contiene y uso como medicamento en profilax
UY26176A1 (es) Formas polimorfas de un citrato de azobiciclo (2,2,2) octan- 3-amina y sus composiciones farmacéuticas.
AR076916A1 (es) Medicamento a base de calcio y de vitamina d. kit.
BRPI0413001A (pt) compostos de sulfonamida, processos de obtenção de seus derivados, medicamentos e usos como moduladores de 5-ht-6
BRPI0604461A (pt) composição farmaceutica estavel de carisoprodol e meloxicam
MY148981A (en) Pharmaceutical formulation
WO2007062262A3 (en) Gelatinous medicament formulation and method of administration
DE50311479D1 (de) Pharmazeutische zusammensetzung, enthaltend oxcarbazepin mit kontrollierter wirkstofffreisetzung

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA INT.CL: A61K 47/04, A61K 47/10, A61K 47/12, A61K 47/14, A61K 47/20, A61K 47/22, A61K 47/24, A61K 47/26, A61K 47/32, A61K 47/34, A61K 47/36, A61K 47/38, A61K 47/44, A61K 9/52, A61K 9/54, A61K 9/58, A61K 47/02

Ipc: A61K 9/48 (2011.01), A61K 9/52 (2011.01), A61K 9/5

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.