BR0115483A - Preparação de pantoprazol seco por congelação e injeção de pantoprazol - Google Patents
Preparação de pantoprazol seco por congelação e injeção de pantoprazolInfo
- Publication number
- BR0115483A BR0115483A BR0115483-4A BR0115483A BR0115483A BR 0115483 A BR0115483 A BR 0115483A BR 0115483 A BR0115483 A BR 0115483A BR 0115483 A BR0115483 A BR 0115483A
- Authority
- BR
- Brazil
- Prior art keywords
- pantoprazole
- injection
- preparation
- freeze
- dried
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00125569 | 2000-11-22 | ||
PCT/EP2001/013296 WO2002041919A1 (en) | 2000-11-22 | 2001-11-17 | Freeze-dried pantoprazole preparation and pantoprazole injection |
Publications (3)
Publication Number | Publication Date |
---|---|
BR0115483A true BR0115483A (pt) | 2003-10-21 |
BRPI0115483B1 BRPI0115483B1 (pt) | 2017-05-09 |
BRPI0115483B8 BRPI0115483B8 (pt) | 2021-05-25 |
Family
ID=8170452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0115483A BRPI0115483B8 (pt) | 2000-11-22 | 2001-11-17 | preparação de pantoprazol seco por congelação e injeção de pantoprazol |
Country Status (40)
Country | Link |
---|---|
US (3) | US6780881B2 (pt) |
EP (2) | EP1762249A3 (pt) |
JP (1) | JP4886158B2 (pt) |
KR (2) | KR100910606B1 (pt) |
CN (1) | CN1250292C (pt) |
AR (2) | AR034277A1 (pt) |
AT (1) | ATE381946T1 (pt) |
AU (2) | AU2002216042B2 (pt) |
BG (1) | BG66329B1 (pt) |
BR (1) | BRPI0115483B8 (pt) |
CA (2) | CA2541946A1 (pt) |
CY (1) | CY1107896T1 (pt) |
CZ (1) | CZ304348B6 (pt) |
DE (1) | DE60132108T2 (pt) |
DK (1) | DK1339430T3 (pt) |
EA (1) | EA007602B1 (pt) |
EC (1) | ECSP034613A (pt) |
EE (1) | EE05236B1 (pt) |
ES (1) | ES2298295T3 (pt) |
GE (1) | GEP20053461B (pt) |
HK (1) | HK1060848A1 (pt) |
HR (1) | HRP20030410B1 (pt) |
HU (1) | HUP0303278A3 (pt) |
IL (2) | IL155601A0 (pt) |
IS (1) | IS2971B (pt) |
ME (1) | ME00556A (pt) |
MX (1) | MXPA03004548A (pt) |
MY (1) | MY137726A (pt) |
NO (1) | NO332937B1 (pt) |
NZ (1) | NZ525911A (pt) |
PE (1) | PE20020582A1 (pt) |
PL (1) | PL201188B1 (pt) |
PT (1) | PT1339430E (pt) |
RS (1) | RS52024B (pt) |
SI (1) | SI1339430T1 (pt) |
SK (1) | SK287993B6 (pt) |
TW (1) | TWI284041B (pt) |
UA (1) | UA80961C2 (pt) |
WO (1) | WO2002041919A1 (pt) |
ZA (1) | ZA200303593B (pt) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY137726A (en) * | 2000-11-22 | 2009-03-31 | Nycomed Gmbh | Freeze-dried pantoprazole preparation and pantoprazole injection |
US20050287231A1 (en) * | 2002-06-21 | 2005-12-29 | Nussen Kenneth H | Method and apparatus for oral hygiene products with green tea extract |
AU2003267763A1 (en) * | 2002-10-25 | 2004-05-13 | Pfizer Products Inc. | Depot formulations of arylheterocyclic active agents in the form of a suspension |
WO2004099183A1 (en) * | 2003-05-06 | 2004-11-18 | Hetero Drugs Limited | Novel polymorphs of pantoprazole sodium |
CL2004000983A1 (es) * | 2003-05-08 | 2005-03-04 | Altana Pharma Ag | Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y |
CN1791406A (zh) * | 2003-05-19 | 2006-06-21 | 普利瓦研究与发展有限公司 | 5-(二氟甲氧基)-2-[[(3,4-二甲氧基-2-吡啶基)甲基]亚硫酰基]-1h-苯并咪唑(泮托拉唑)钠水络合物的固态形式 |
AR045258A1 (es) * | 2003-08-21 | 2005-10-19 | Altana Pharma Ag | Un producto farmaceutico para inyeccion |
WO2005070426A1 (en) * | 2004-01-27 | 2005-08-04 | Altana Pharma Ag | Freeze-dried (-)-pantoprazole preparation and (-)-pantoprazole injection |
DE102004007854A1 (de) * | 2004-02-17 | 2005-09-01 | Hexal Ag | Stabile, wässrige Formulierung für Benzimidazole |
US20060085924A1 (en) * | 2004-10-13 | 2006-04-27 | Gaelle Brun | Coloring composition comprising at least one pigment and at least one electrophilic cyanoacrylate monomer |
CN1293879C (zh) * | 2005-01-20 | 2007-01-10 | 杭州华东医药集团生物工程研究所有限公司 | 泮托拉唑钠冻干粉针剂及其制备方法 |
CN101309917B (zh) * | 2005-10-06 | 2013-09-11 | 奥斯拜客斯制药有限公司 | 具有增强治疗性质的胃h+,k+-atp酶氘代抑制剂 |
WO2009001163A1 (en) * | 2006-06-01 | 2008-12-31 | Combino Pharm, S.L. | Lyophilized preparations of pantoprazole sodium for injection |
BRPI0715113A2 (pt) | 2006-07-26 | 2013-06-04 | Sandoz Ag Sandoz Sa Sandoz Ltd | formulaÇço de caspofungina |
US7979200B2 (en) * | 2006-11-20 | 2011-07-12 | Lockheed Martin Corporation | Managing an air-ground communications network with air traffic control information |
EP2106788A1 (en) * | 2008-04-04 | 2009-10-07 | Ipsen Pharma | Liquid and freeze dried formulations |
CN101744777B (zh) * | 2009-12-30 | 2012-09-26 | 北京四环科宝制药有限公司 | 奥美拉唑钠冻干粉针剂及制备方法和检测方法 |
CN101961309B (zh) * | 2010-09-15 | 2012-06-27 | 河南辅仁怀庆堂制药有限公司 | 注射用泮托拉唑钠配制工艺 |
CN102000034B (zh) * | 2010-10-13 | 2011-12-21 | 江苏奥赛康药业股份有限公司 | 一种供注射用的s-泮托拉唑钠组合物及其制备方法 |
CN102225063B (zh) * | 2011-05-10 | 2012-10-10 | 江苏奥赛康药业股份有限公司 | 一种供注射用的泮托拉唑钠组合物 |
TR201108946A2 (tr) * | 2011-09-12 | 2012-04-24 | World Medicine İlaç Sanayi̇ Ve Ti̇caret Li̇mi̇ted Şi̇rketi̇ | Dondurularak kurutulmuş atp, vitamin b kompleksi preparatı ve enjeksiyonu. |
NZ703528A (en) * | 2012-06-27 | 2016-08-26 | Takeda Pharmaceutical | Liquid preparations of amines and organic acids stabilized by salts |
CN104000786A (zh) * | 2013-02-25 | 2014-08-27 | 杭州赛利药物研究所有限公司 | 泮托拉唑钠冻干制剂及其制备方法 |
CN104414979A (zh) * | 2013-08-21 | 2015-03-18 | 哈药集团三精制药股份有限公司 | 一种泮托拉唑钠冻干粉针剂及其制备方法 |
CN104019635B (zh) * | 2014-06-19 | 2015-05-27 | 上海慈瑞医药科技有限公司 | 一种兰索拉唑原料药化合物及其干燥工艺 |
CN104055791A (zh) * | 2014-07-10 | 2014-09-24 | 北京人福军威医药技术开发有限公司 | 西地碘治疗眼角结膜炎的用途 |
CN104055792A (zh) * | 2014-07-10 | 2014-09-24 | 北京人福军威医药技术开发有限公司 | 西地碘治疗中耳炎的用途 |
BE1021311B1 (nl) * | 2014-07-31 | 2015-10-28 | Neogen N.V. | Werkwijze voor het maken van een poedervormige protonpompremmer samenstelling, genoemde samenstelling en gebruik |
US20170042806A1 (en) | 2015-04-29 | 2017-02-16 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
CN111643460A (zh) * | 2020-06-30 | 2020-09-11 | 武汉九州钰民医药科技有限公司 | 泮托拉唑钠冻干制剂及其制备方法、由其制得的注射制剂 |
CN112274481A (zh) * | 2020-10-27 | 2021-01-29 | 海南卫康制药(潜山)有限公司 | 一种注射用泮托拉唑钠组合物及其制备方法 |
Family Cites Families (21)
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SE8301182D0 (sv) | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
IL75400A (en) * | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
DK399389A (da) | 1988-08-18 | 1990-02-19 | Takeda Chemical Industries Ltd | Injicerbare oploesninger |
US5223515A (en) | 1988-08-18 | 1993-06-29 | Takeda Chemical Industries, Ltd. | Injectable solution containing a pyridyl methylsulfinylbenzimidazole |
DE4035455A1 (de) | 1990-11-08 | 1992-05-14 | Byk Gulden Lomberg Chem Fab | Enantiomerentrennung |
KR100258423B1 (ko) | 1992-07-28 | 2000-07-01 | 클래스 빌헬름슨 | 오메프라졸 및 그의 동족체를 함유하는 주사제 및 주사제 키트 |
EP0695123A4 (en) | 1993-04-27 | 1996-09-11 | Sepracor Inc | METHOD AND COMPOSITIONS FOR TREATING GASTRICAL FAULTS USING OPTICALLY PURE PANTOPRAZOLS |
DE4324014C2 (de) * | 1993-07-17 | 1995-06-08 | Byk Gulden Lomberg Chem Fab | Verfahren zur Herstellung einer in Wasser rekonstituierbaren Zubereitung |
TW280770B (pt) | 1993-10-15 | 1996-07-11 | Takeda Pharm Industry Co Ltd | |
HU224987B1 (en) | 1995-11-03 | 2006-05-29 | Sanofi Aventis | Stable freeze-dried pharmaceutical formulation |
FR2740686B1 (fr) | 1995-11-03 | 1998-01-16 | Sanofi Sa | Formulation pharmaceutique lyophilisee stable |
US5980882A (en) | 1997-04-16 | 1999-11-09 | Medeva Pharmaceuticals Manufacturing | Drug-resin complexes stabilized by chelating agents |
ES2268800T3 (es) | 1997-10-14 | 2007-03-16 | Eisai Co., Ltd. | Formulacion farmaceutica que comprende glicina como estabilizador. |
DE19843413C1 (de) * | 1998-08-18 | 2000-03-30 | Byk Gulden Lomberg Chem Fab | Neue Salzform von Pantoprazol |
WO2000026185A2 (en) | 1998-10-30 | 2000-05-11 | The Curators Of The University Of Missouri | Omeprazole solution and method of using same |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
CN1235018A (zh) * | 1999-04-22 | 1999-11-17 | 沈阳东宇药业有限公司 | 泮托拉唑钠冻干粉针剂及制备方法 |
SE9903831D0 (sv) * | 1999-10-22 | 1999-10-22 | Astra Ab | Formulation of substituted benzimidazoles |
US7396841B2 (en) * | 2000-08-18 | 2008-07-08 | Takeda Pharmaceutical Company Limited | Injections |
MY137726A (en) * | 2000-11-22 | 2009-03-31 | Nycomed Gmbh | Freeze-dried pantoprazole preparation and pantoprazole injection |
AR045258A1 (es) | 2003-08-21 | 2005-10-19 | Altana Pharma Ag | Un producto farmaceutico para inyeccion |
-
2001
- 2001-10-19 MY MYPI20014865A patent/MY137726A/en unknown
- 2001-11-06 TW TW090127545A patent/TWI284041B/zh not_active IP Right Cessation
- 2001-11-17 PL PL361118A patent/PL201188B1/pl unknown
- 2001-11-17 JP JP2002544096A patent/JP4886158B2/ja not_active Expired - Fee Related
- 2001-11-17 EP EP06123558.6A patent/EP1762249A3/en not_active Ceased
- 2001-11-17 SI SI200130816T patent/SI1339430T1/sl unknown
- 2001-11-17 AU AU2002216042A patent/AU2002216042B2/en not_active Expired
- 2001-11-17 KR KR1020037006675A patent/KR100910606B1/ko active IP Right Grant
- 2001-11-17 CZ CZ2003-1416A patent/CZ304348B6/cs not_active IP Right Cessation
- 2001-11-17 PT PT01997314T patent/PT1339430E/pt unknown
- 2001-11-17 EA EA200300501A patent/EA007602B1/ru not_active IP Right Cessation
- 2001-11-17 GE GE5180A patent/GEP20053461B/en unknown
- 2001-11-17 WO PCT/EP2001/013296 patent/WO2002041919A1/en active IP Right Grant
- 2001-11-17 UA UA20040705223A patent/UA80961C2/uk unknown
- 2001-11-17 SK SK606-2003A patent/SK287993B6/sk not_active IP Right Cessation
- 2001-11-17 KR KR1020077027736A patent/KR100910607B1/ko active IP Right Grant
- 2001-11-17 HU HU0303278A patent/HUP0303278A3/hu unknown
- 2001-11-17 CA CA002541946A patent/CA2541946A1/en not_active Abandoned
- 2001-11-17 ME MEP-696/08A patent/ME00556A/xx unknown
- 2001-11-17 DK DK01997314T patent/DK1339430T3/da active
- 2001-11-17 MX MXPA03004548A patent/MXPA03004548A/es active IP Right Grant
- 2001-11-17 CN CNB01819379XA patent/CN1250292C/zh not_active Expired - Lifetime
- 2001-11-17 DE DE60132108T patent/DE60132108T2/de not_active Expired - Lifetime
- 2001-11-17 EP EP01997314A patent/EP1339430B1/en not_active Revoked
- 2001-11-17 AU AU1604202A patent/AU1604202A/xx active Pending
- 2001-11-17 EE EEP200300182A patent/EE05236B1/xx not_active IP Right Cessation
- 2001-11-17 IL IL15560101A patent/IL155601A0/xx unknown
- 2001-11-17 CA CA002428870A patent/CA2428870C/en not_active Expired - Lifetime
- 2001-11-17 BR BRPI0115483A patent/BRPI0115483B8/pt not_active IP Right Cessation
- 2001-11-17 NZ NZ525911A patent/NZ525911A/en not_active IP Right Cessation
- 2001-11-17 ES ES01997314T patent/ES2298295T3/es not_active Expired - Lifetime
- 2001-11-17 AT AT01997314T patent/ATE381946T1/de active
- 2001-11-17 RS YU37703A patent/RS52024B/sr unknown
- 2001-11-19 PE PE2001001153A patent/PE20020582A1/es active IP Right Grant
- 2001-11-19 AR ARP010105391A patent/AR034277A1/es not_active Application Discontinuation
-
2002
- 2002-07-15 US US10/195,062 patent/US6780881B2/en not_active Expired - Lifetime
-
2003
- 2003-04-28 IL IL155601A patent/IL155601A/en active IP Right Grant
- 2003-05-09 ZA ZA200303593A patent/ZA200303593B/en unknown
- 2003-05-19 IS IS6820A patent/IS2971B/is unknown
- 2003-05-19 EC EC2003004613A patent/ECSP034613A/es unknown
- 2003-05-20 BG BG107828A patent/BG66329B1/bg unknown
- 2003-05-21 NO NO20032303A patent/NO332937B1/no not_active IP Right Cessation
- 2003-05-21 HR HR20030410A patent/HRP20030410B1/xx not_active IP Right Cessation
-
2004
- 2004-05-28 HK HK04103845A patent/HK1060848A1/xx not_active IP Right Cessation
- 2004-05-28 US US10/855,703 patent/US7351723B2/en not_active Expired - Lifetime
-
2008
- 2008-01-22 US US12/010,124 patent/US8754108B2/en not_active Expired - Lifetime
- 2008-02-28 CY CY20081100226T patent/CY1107896T1/el unknown
-
2013
- 2013-08-21 AR ARP130102967A patent/AR092374A2/es not_active Application Discontinuation
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