DE60009926D1 - Stabilisierung von gefriergetrocknetem kuchen - Google Patents

Stabilisierung von gefriergetrocknetem kuchen

Info

Publication number
DE60009926D1
DE60009926D1 DE60009926T DE60009926T DE60009926D1 DE 60009926 D1 DE60009926 D1 DE 60009926D1 DE 60009926 T DE60009926 T DE 60009926T DE 60009926 T DE60009926 T DE 60009926T DE 60009926 D1 DE60009926 D1 DE 60009926D1
Authority
DE
Germany
Prior art keywords
stabilizing
freeze dried
dried cake
freeze
sugar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60009926T
Other languages
English (en)
Other versions
DE60009926T2 (de
Inventor
Lindgaard Hansen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk Health Care AG
Original Assignee
Novo Nordisk Health Care AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk Health Care AG filed Critical Novo Nordisk Health Care AG
Application granted granted Critical
Publication of DE60009926D1 publication Critical patent/DE60009926D1/de
Publication of DE60009926T2 publication Critical patent/DE60009926T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Preparation Of Fruits And Vegetables (AREA)
  • Freezing, Cooling And Drying Of Foods (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
DE60009926T 1999-08-17 2000-08-16 Stabilisierung von gefriergetrocknetem kuchen Expired - Lifetime DE60009926T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199901130 1999-08-17
DK113099 1999-08-17
PCT/DK2000/000454 WO2001012653A1 (en) 1999-08-17 2000-08-16 Stabilisation of freeze-dried cake

Publications (2)

Publication Number Publication Date
DE60009926D1 true DE60009926D1 (de) 2004-05-19
DE60009926T2 DE60009926T2 (de) 2005-04-07

Family

ID=8101362

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60009926T Expired - Lifetime DE60009926T2 (de) 1999-08-17 2000-08-16 Stabilisierung von gefriergetrocknetem kuchen

Country Status (6)

Country Link
EP (1) EP1210361B1 (de)
JP (1) JP2003507388A (de)
AT (1) ATE264340T1 (de)
AU (1) AU6558400A (de)
DE (1) DE60009926T2 (de)
WO (1) WO2001012653A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1458408B1 (de) 2001-12-21 2009-04-15 Novo Nordisk Health Care AG Flüssige zusammensetzung aus faktor vii polypeptiden
GB0207092D0 (en) * 2002-03-26 2002-05-08 Sod Conseils Rech Applic Stable pharmaceutical composition containing factor VIII
PL224150B1 (pl) * 2002-05-02 2016-11-30 Wyeth Corp Kompozycja zawierająca koniugat leku obejmujący pochodne kalicheamycyny i przeciwciało, oraz kompozycja farmaceutyczna ją zawierająca
WO2003092731A1 (en) * 2002-05-03 2003-11-13 Novo Nordisk A/S Stabilised solid compositions of modified factor vii
CN101912601B (zh) 2002-06-21 2012-08-29 诺和诺德医疗保健公司 因子vii多肽的稳定化固体组合物
KR101204712B1 (ko) * 2003-03-18 2012-11-27 노보 노르디스크 헬스 케어 악티엔게젤샤프트 Ｇｌａ-잔기 함유 세린 프로테아제의 제조 방법
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
JP4658041B2 (ja) 2003-06-25 2011-03-23 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト Ｖｉｉ因子ポリペプチドの液体組成物
EP2311437A1 (de) * 2003-12-19 2011-04-20 Novo Nordisk Health Care AG Stabilisierte Zusammensetzungen von Faktor-VII-Polypeptiden
AU2011203354B2 (en) * 2003-12-19 2014-07-17 Novo Nordisk Health Care Ag Stabilised compositions of factor VII polypeptides
PT2337580E (pt) * 2008-09-03 2012-05-28 Octapharma Ag Composições estabilizadas para o factor viii produzido de forma recombinante
FR2947181B1 (fr) * 2009-06-26 2012-05-04 Lfb Biotechnologies Composition de facteur vii
EP3511336B1 (de) * 2011-06-28 2023-06-21 Leukocare Ag Verfahren zum verhindern der entfaltung eines (poly)peptids und/oder zum induzieren der (neu-)faltung eines (poly)peptids
WO2017076967A1 (en) * 2015-11-05 2017-05-11 Novo Nordisk A/S Fviii formulation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT308050B (de) * 1970-08-28 1973-06-25 Boehringer Mannheim Gmbh Reagens zur Bestimmung der γ-Glutamyltranspeptidase
US4777043A (en) * 1985-12-17 1988-10-11 Genentech, Inc. Stabilized human tissue plasminogen activator compositions
JPH0650999B2 (ja) * 1988-09-12 1994-07-06 日本商事株式会社 血液凝固因子安定化法
US5656730A (en) * 1995-04-07 1997-08-12 Enzon, Inc. Stabilized monomeric protein compositions

Also Published As

Publication number Publication date
EP1210361B1 (de) 2004-04-14
DE60009926T2 (de) 2005-04-07
AU6558400A (en) 2001-03-13
EP1210361A1 (de) 2002-06-05
WO2001012653A1 (en) 2001-02-22
ATE264340T1 (de) 2004-04-15
JP2003507388A (ja) 2003-02-25

Similar Documents

Publication Publication Date Title
DE60009926D1 (de) Stabilisierung von gefriergetrocknetem kuchen
DE69717815T2 (de) Verbesserungen von kreatin-zusammensetzungen
DE60024612D1 (de) Verfahren zur herstellung von konditionierten zellkulturmedium-zusammensetzungen
ATE246197T1 (de) Neue heteroaromatische fructose 1,6- bisphosphatase inhibitoren
DE69940354D1 (de) Adenovirus-formulierungen zur gentherapie
FI962799A (fi) Nukleiinihappoja sisältävä valmiste, sen valmistus ja käyttö
BR0108396A (pt) Derivados de pirimidina-4-0na como inibidores de ldl-pla(2)
BR9910251A (pt) Estimulação hematopoiética
WO2001041800A3 (en) Compositions and methods for stabilizing biological molecules upon lyophilization
ITRM980103A0 (it) Uso di batteri dotati di arginina deiminasi per introdurre apostosi e/o ridurre una reazione infiammatoria e composizioni farmaceutiche
EP1329458A3 (de) Peptide, die den Blutzuckergehalt senken
WO2002049593A3 (de) Verwendung von dna-reparatur-enzymen als mmp-1-inhibitoren
EP1308170A3 (de) Getrocknete Blutfaktorzusammensetzung mit Trehalose
HUP0303278A2 (hu) Fagyasztva szárított pantoprazol készítmény, eljárás az előállítására és pantoprazol injekció
ATE281466T1 (de) Niedermolekulare inhibitoren von komplementproteasen
IL132951A0 (en) Compounds preparation and use for transferring nucleic acids into cells
WO1997028181A3 (en) Post-labeling stabilization of radiolabeled proteins and peptides
BRPI0517305A (pt) formulação liofilizada estabilizada para derivados de cefalosporina
CA2256410A1 (en) Stable pharmaceutical composition of bdnf
WO2003053180A3 (de) Wirkstoffhaltige unterwäsche
MXPA04001256A (es) Productos de combinacion de derivados de propanolamina aril substituidos con otros ingredientes activos y su uso.
TR200002101T2 (tr) Dondurulmuş gıda ürünü.
TR200400639T4 (tr) Donmaya-karşı proteinler, bunların üretimleri ve kullanımları
WO2001056456A3 (en) Methods and compositions for detection of disease
FR2808195B1 (fr) Patch cosmetique ou dermatologique lyophilise

Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition