AR092374A2 - Preparacion liofilizada de 5-difluorometoxi-2-[(3,4-dimetoxi-2-piridinil)metilsulfinil]-1h-bencimidazol (pantoprazol) - Google Patents

Preparacion liofilizada de 5-difluorometoxi-2-[(3,4-dimetoxi-2-piridinil)metilsulfinil]-1h-bencimidazol (pantoprazol)

Info

Publication number
AR092374A2
AR092374A2 ARP130102967A ARP130102967A AR092374A2 AR 092374 A2 AR092374 A2 AR 092374A2 AR P130102967 A ARP130102967 A AR P130102967A AR P130102967 A ARP130102967 A AR P130102967A AR 092374 A2 AR092374 A2 AR 092374A2
Authority
AR
Argentina
Prior art keywords
metilsulfinil
difluorometoxi
piridinil
dimetoxi
liofilized
Prior art date
Application number
ARP130102967A
Other languages
English (en)
Inventor
Dr Linder Rudolf
Dr Dietrich Rango
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8170452&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR092374(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of AR092374A2 publication Critical patent/AR092374A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Reivindicación 1: Una preparación liofilizada caracterizada porque consiste en: (a) 5-difluorometoxi-2-[(3,4-dimetoxi-2-piridinil)metilsulfinil]-1H-bencimidazol (pantoprazol) o un solvato, hidrato, sal, hidrato de una sal o solvato de una sal del mismo, (b) ácido etilendiaminotetraacético y/o una sal adecuada del mismo, y (c) hidróxido de sodio y/o carbonato de sodio.
ARP130102967A 2000-11-22 2013-08-21 Preparacion liofilizada de 5-difluorometoxi-2-[(3,4-dimetoxi-2-piridinil)metilsulfinil]-1h-bencimidazol (pantoprazol) AR092374A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00125569 2000-11-22

Publications (1)

Publication Number Publication Date
AR092374A2 true AR092374A2 (es) 2015-04-15

Family

ID=8170452

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP010105391A AR034277A1 (es) 2000-11-22 2001-11-19 Proceso para la produccion de una preparacion liofilizada de pantoprazol, preparacion liofilizada de pantoprazol obtenida, inyeccion de pantoprazol obtenida por reconstitucion en un disolvente y kit de inyeccion
ARP130102967A AR092374A2 (es) 2000-11-22 2013-08-21 Preparacion liofilizada de 5-difluorometoxi-2-[(3,4-dimetoxi-2-piridinil)metilsulfinil]-1h-bencimidazol (pantoprazol)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP010105391A AR034277A1 (es) 2000-11-22 2001-11-19 Proceso para la produccion de una preparacion liofilizada de pantoprazol, preparacion liofilizada de pantoprazol obtenida, inyeccion de pantoprazol obtenida por reconstitucion en un disolvente y kit de inyeccion

Country Status (40)

Country Link
US (3) US6780881B2 (es)
EP (2) EP1339430B1 (es)
JP (1) JP4886158B2 (es)
KR (2) KR100910607B1 (es)
CN (1) CN1250292C (es)
AR (2) AR034277A1 (es)
AT (1) ATE381946T1 (es)
AU (2) AU1604202A (es)
BG (1) BG66329B1 (es)
BR (1) BRPI0115483B8 (es)
CA (2) CA2428870C (es)
CY (1) CY1107896T1 (es)
CZ (1) CZ304348B6 (es)
DE (1) DE60132108T2 (es)
DK (1) DK1339430T3 (es)
EA (1) EA007602B1 (es)
EC (1) ECSP034613A (es)
EE (1) EE05236B1 (es)
ES (1) ES2298295T3 (es)
GE (1) GEP20053461B (es)
HK (1) HK1060848A1 (es)
HR (1) HRP20030410B1 (es)
HU (1) HUP0303278A3 (es)
IL (2) IL155601A0 (es)
IS (1) IS2971B (es)
ME (1) ME00556A (es)
MX (1) MXPA03004548A (es)
MY (1) MY137726A (es)
NO (1) NO332937B1 (es)
NZ (1) NZ525911A (es)
PE (1) PE20020582A1 (es)
PL (1) PL201188B1 (es)
PT (1) PT1339430E (es)
RS (1) RS52024B (es)
SI (1) SI1339430T1 (es)
SK (1) SK287993B6 (es)
TW (1) TWI284041B (es)
UA (1) UA80961C2 (es)
WO (1) WO2002041919A1 (es)
ZA (1) ZA200303593B (es)

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CN1791406A (zh) * 2003-05-19 2006-06-21 普利瓦研究与发展有限公司 5－(二氟甲氧基)－2－[[(3,4－二甲氧基－2－吡啶基)甲基]亚硫酰基]－1h－苯并咪唑(泮托拉唑)钠水络合物的固态形式
AR045258A1 (es) * 2003-08-21 2005-10-19 Altana Pharma Ag Un producto farmaceutico para inyeccion
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CN102225063B (zh) * 2011-05-10 2012-10-10 江苏奥赛康药业股份有限公司 一种供注射用的泮托拉唑钠组合物
TR201108946A2 (tr) * 2011-09-12 2012-04-24 World Medicine İlaç Sanayi̇ Ve Ti̇caret Li̇mi̇ted Şi̇rketi̇ Dondurularak kurutulmuş atp, vitamin b kompleksi preparatı ve enjeksiyonu.
WO2014003199A1 (en) * 2012-06-27 2014-01-03 Takeda Pharmaceutical Company Limited Liquid preparations of amines and organic acids stabilized by salts
CN104000786A (zh) * 2013-02-25 2014-08-27 杭州赛利药物研究所有限公司 泮托拉唑钠冻干制剂及其制备方法
CN104414979A (zh) * 2013-08-21 2015-03-18 哈药集团三精制药股份有限公司 一种泮托拉唑钠冻干粉针剂及其制备方法
CN104019635B (zh) * 2014-06-19 2015-05-27 上海慈瑞医药科技有限公司 一种兰索拉唑原料药化合物及其干燥工艺
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CN104055792A (zh) * 2014-07-10 2014-09-24 北京人福军威医药技术开发有限公司 西地碘治疗中耳炎的用途
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Also Published As

Publication number Publication date
BR0115483A (pt) 2003-10-21
JP2004513970A (ja) 2004-05-13
ES2298295T3 (es) 2008-05-16
CA2428870A1 (en) 2002-05-30
AU2002216042B2 (en) 2006-08-03
BRPI0115483B8 (pt) 2021-05-25
HRP20030410B1 (en) 2011-02-28
IS6820A (is) 2003-05-19
YU37703A (sh) 2006-05-25
NO20032303D0 (no) 2003-05-21
TWI284041B (en) 2007-07-21
SK287993B6 (sk) 2012-09-03
SK6062003A3 (en) 2003-10-07
PE20020582A1 (es) 2002-07-06
SI1339430T1 (sl) 2008-06-30
EA200300501A1 (ru) 2003-12-25
NZ525911A (en) 2004-11-26
EP1762249A2 (en) 2007-03-14
US20040220228A1 (en) 2004-11-04
EE05236B1 (et) 2009-12-15
HK1060848A1 (en) 2004-08-27
PL201188B1 (pl) 2009-03-31
KR20030055308A (ko) 2003-07-02
EP1339430A1 (en) 2003-09-03
ECSP034613A (es) 2003-08-29
AR034277A1 (es) 2004-02-18
US20030003058A1 (en) 2003-01-02
HUP0303278A2 (hu) 2004-01-28
JP4886158B2 (ja) 2012-02-29
US7351723B2 (en) 2008-04-01
ME00556B (me) 2011-12-20
CZ20031416A3 (cs) 2003-09-17
DE60132108T2 (de) 2008-12-11
MY137726A (en) 2009-03-31
DK1339430T3 (da) 2008-05-13
BG66329B1 (bg) 2013-06-28
KR100910607B1 (ko) 2009-08-04
ATE381946T1 (de) 2008-01-15
US20090093522A1 (en) 2009-04-09
CN1476335A (zh) 2004-02-18
HUP0303278A3 (en) 2007-08-28
BG107828A (bg) 2004-07-30
MXPA03004548A (es) 2003-09-10
CN1250292C (zh) 2006-04-12
BRPI0115483B1 (pt) 2017-05-09
IS2971B (is) 2017-05-15
RS52024B (sr) 2012-04-30
EP1762249A3 (en) 2014-05-14
IL155601A (en) 2008-12-29
EA007602B1 (ru) 2006-12-29
CZ304348B6 (cs) 2014-03-19
KR100910606B1 (ko) 2009-08-04
UA80961C2 (en) 2007-11-26
KR20080003010A (ko) 2008-01-04
US8754108B2 (en) 2014-06-17
ME00556A (en) 2011-12-20
PT1339430E (pt) 2008-03-27
DE60132108D1 (de) 2008-02-07
ZA200303593B (en) 2004-04-23
HRP20030410A2 (en) 2005-04-30
IL155601A0 (en) 2003-11-23
CY1107896T1 (el) 2013-09-04
PL361118A1 (en) 2004-09-20
AU1604202A (en) 2002-06-03
CA2428870C (en) 2006-05-23
US6780881B2 (en) 2004-08-24
NO20032303L (no) 2003-05-21
WO2002041919A1 (en) 2002-05-30
EE200300182A (et) 2003-06-16
GEP20053461B (en) 2005-02-25
EP1339430B1 (en) 2007-12-26
NO332937B1 (no) 2013-02-04
CA2541946A1 (en) 2002-05-30

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