AR034277A1 - Proceso para la produccion de una preparacion liofilizada de pantoprazol, preparacion liofilizada de pantoprazol obtenida, inyeccion de pantoprazol obtenida por reconstitucion en un disolvente y kit de inyeccion - Google Patents
Proceso para la produccion de una preparacion liofilizada de pantoprazol, preparacion liofilizada de pantoprazol obtenida, inyeccion de pantoprazol obtenida por reconstitucion en un disolvente y kit de inyeccionInfo
- Publication number
- AR034277A1 AR034277A1 ARP010105391A ARP010105391A AR034277A1 AR 034277 A1 AR034277 A1 AR 034277A1 AR P010105391 A ARP010105391 A AR P010105391A AR P010105391 A ARP010105391 A AR P010105391A AR 034277 A1 AR034277 A1 AR 034277A1
- Authority
- AR
- Argentina
- Prior art keywords
- pantoprazol
- preparation
- injection
- liophilized
- pantoprazole
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Abstract
Proceso para la producción de una preparación liofilizada que comprende 5-difluorometoxi-2-[(3,4-dimetoxi-2-pirimidinil)metilsulfinil]-1-H-bencimidazol (pantoprazol), una sal del mismo, un solvato de pantoprazol o una sal del mismo, que comprende liofilizar una solución acuosa de pantroprazol, una sal del mismo, un solvato de pantoprazol o una sal del mismo, ácido etilenodiaminotetraacético y/o una sal de adecuada del mismo, e hidróxido de sodio y/o carbonato de sodio.Se describe una preparación liofilizada de pantoprazol, así como una inyección obtenible por reconstitución de la preparación liofilizada de pantoprazol en un disolvente adecuado y un kit para inyección.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00125569 | 2000-11-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR034277A1 true AR034277A1 (es) | 2004-02-18 |
Family
ID=8170452
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP010105391A AR034277A1 (es) | 2000-11-22 | 2001-11-19 | Proceso para la produccion de una preparacion liofilizada de pantoprazol, preparacion liofilizada de pantoprazol obtenida, inyeccion de pantoprazol obtenida por reconstitucion en un disolvente y kit de inyeccion |
ARP130102967A AR092374A2 (es) | 2000-11-22 | 2013-08-21 | Preparacion liofilizada de 5-difluorometoxi-2-[(3,4-dimetoxi-2-piridinil)metilsulfinil]-1h-bencimidazol (pantoprazol) |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP130102967A AR092374A2 (es) | 2000-11-22 | 2013-08-21 | Preparacion liofilizada de 5-difluorometoxi-2-[(3,4-dimetoxi-2-piridinil)metilsulfinil]-1h-bencimidazol (pantoprazol) |
Country Status (40)
Country | Link |
---|---|
US (3) | US6780881B2 (es) |
EP (2) | EP1339430B1 (es) |
JP (1) | JP4886158B2 (es) |
KR (2) | KR100910606B1 (es) |
CN (1) | CN1250292C (es) |
AR (2) | AR034277A1 (es) |
AT (1) | ATE381946T1 (es) |
AU (2) | AU1604202A (es) |
BG (1) | BG66329B1 (es) |
BR (1) | BRPI0115483B8 (es) |
CA (2) | CA2541946A1 (es) |
CY (1) | CY1107896T1 (es) |
CZ (1) | CZ304348B6 (es) |
DE (1) | DE60132108T2 (es) |
DK (1) | DK1339430T3 (es) |
EA (1) | EA007602B1 (es) |
EC (1) | ECSP034613A (es) |
EE (1) | EE05236B1 (es) |
ES (1) | ES2298295T3 (es) |
GE (1) | GEP20053461B (es) |
HK (1) | HK1060848A1 (es) |
HR (1) | HRP20030410B1 (es) |
HU (1) | HUP0303278A3 (es) |
IL (2) | IL155601A0 (es) |
IS (1) | IS2971B (es) |
ME (1) | ME00556A (es) |
MX (1) | MXPA03004548A (es) |
MY (1) | MY137726A (es) |
NO (1) | NO332937B1 (es) |
NZ (1) | NZ525911A (es) |
PE (1) | PE20020582A1 (es) |
PL (1) | PL201188B1 (es) |
PT (1) | PT1339430E (es) |
RS (1) | RS52024B (es) |
SI (1) | SI1339430T1 (es) |
SK (1) | SK287993B6 (es) |
TW (1) | TWI284041B (es) |
UA (1) | UA80961C2 (es) |
WO (1) | WO2002041919A1 (es) |
ZA (1) | ZA200303593B (es) |
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MY137726A (en) * | 2000-11-22 | 2009-03-31 | Nycomed Gmbh | Freeze-dried pantoprazole preparation and pantoprazole injection |
US20050287231A1 (en) * | 2002-06-21 | 2005-12-29 | Nussen Kenneth H | Method and apparatus for oral hygiene products with green tea extract |
CA2498276A1 (en) * | 2002-10-25 | 2004-05-06 | Pfizer Products Inc. | Depot formulations of arylheterocyclic active agents in the form of a suspension |
AU2003241150A1 (en) * | 2003-05-06 | 2004-11-26 | Hetero Drugs Limited | Novel polymorphs of pantoprazole sodium |
CL2004000983A1 (es) * | 2003-05-08 | 2005-03-04 | Altana Pharma Ag | Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y |
US20050004172A1 (en) * | 2003-05-19 | 2005-01-06 | Pliva-Istrazivacki Institut D.O.O. | Solid state forms of 5-(difluoro-methoxy)-2-((3,4-dimethoxy-2-pyridinyl)-methyl) sulfinyl]-1H-benzimidazole sodium aquo complexes |
AR045258A1 (es) * | 2003-08-21 | 2005-10-19 | Altana Pharma Ag | Un producto farmaceutico para inyeccion |
WO2005070426A1 (en) * | 2004-01-27 | 2005-08-04 | Altana Pharma Ag | Freeze-dried (-)-pantoprazole preparation and (-)-pantoprazole injection |
DE102004007854A1 (de) * | 2004-02-17 | 2005-09-01 | Hexal Ag | Stabile, wässrige Formulierung für Benzimidazole |
US20060085924A1 (en) * | 2004-10-13 | 2006-04-27 | Gaelle Brun | Coloring composition comprising at least one pigment and at least one electrophilic cyanoacrylate monomer |
CN1293879C (zh) * | 2005-01-20 | 2007-01-10 | 杭州华东医药集团生物工程研究所有限公司 | 泮托拉唑钠冻干粉针剂及其制备方法 |
CA2624179A1 (en) * | 2005-10-06 | 2007-04-12 | Auspex Pharmaceuticals, Inc. | Deuterated inhibitors of gastric h+, k+-atpase with enhanced therapeutic properties |
WO2009001163A1 (en) * | 2006-06-01 | 2008-12-31 | Combino Pharm, S.L. | Lyophilized preparations of pantoprazole sodium for injection |
SI2049142T2 (sl) | 2006-07-26 | 2016-04-29 | Sandoz Ag | Formulacije kaspofungina |
US7979200B2 (en) * | 2006-11-20 | 2011-07-12 | Lockheed Martin Corporation | Managing an air-ground communications network with air traffic control information |
EP2106788A1 (en) * | 2008-04-04 | 2009-10-07 | Ipsen Pharma | Liquid and freeze dried formulations |
CN101744777B (zh) * | 2009-12-30 | 2012-09-26 | 北京四环科宝制药有限公司 | 奥美拉唑钠冻干粉针剂及制备方法和检测方法 |
CN101961309B (zh) * | 2010-09-15 | 2012-06-27 | 河南辅仁怀庆堂制药有限公司 | 注射用泮托拉唑钠配制工艺 |
CN102000034B (zh) * | 2010-10-13 | 2011-12-21 | 江苏奥赛康药业股份有限公司 | 一种供注射用的s-泮托拉唑钠组合物及其制备方法 |
CN102225063B (zh) * | 2011-05-10 | 2012-10-10 | 江苏奥赛康药业股份有限公司 | 一种供注射用的泮托拉唑钠组合物 |
TR201108946A2 (tr) * | 2011-09-12 | 2012-04-24 | World Medicine İlaç Sanayi̇ Ve Ti̇caret Li̇mi̇ted Şi̇rketi̇ | Dondurularak kurutulmuş atp, vitamin b kompleksi preparatı ve enjeksiyonu. |
MX2014015269A (es) * | 2012-06-27 | 2015-02-20 | Takeda Pharmaceutical | Preparaciones liquidas de aminas y acidos organicos estabilizados por sales. |
CN104000786A (zh) * | 2013-02-25 | 2014-08-27 | 杭州赛利药物研究所有限公司 | 泮托拉唑钠冻干制剂及其制备方法 |
CN104414979A (zh) * | 2013-08-21 | 2015-03-18 | 哈药集团三精制药股份有限公司 | 一种泮托拉唑钠冻干粉针剂及其制备方法 |
CN104019635B (zh) * | 2014-06-19 | 2015-05-27 | 上海慈瑞医药科技有限公司 | 一种兰索拉唑原料药化合物及其干燥工艺 |
CN104055791A (zh) * | 2014-07-10 | 2014-09-24 | 北京人福军威医药技术开发有限公司 | 西地碘治疗眼角结膜炎的用途 |
CN104055792A (zh) * | 2014-07-10 | 2014-09-24 | 北京人福军威医药技术开发有限公司 | 西地碘治疗中耳炎的用途 |
BE1021311B1 (nl) * | 2014-07-31 | 2015-10-28 | Neogen N.V. | Werkwijze voor het maken van een poedervormige protonpompremmer samenstelling, genoemde samenstelling en gebruik |
US20170042806A1 (en) | 2015-04-29 | 2017-02-16 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
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CN111643460A (zh) * | 2020-06-30 | 2020-09-11 | 武汉九州钰民医药科技有限公司 | 泮托拉唑钠冻干制剂及其制备方法、由其制得的注射制剂 |
CN112274481A (zh) * | 2020-10-27 | 2021-01-29 | 海南卫康制药(潜山)有限公司 | 一种注射用泮托拉唑钠组合物及其制备方法 |
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CA2419067C (en) * | 2000-08-18 | 2008-12-23 | Takeda Chemical Industries, Ltd. | Injectable composition comprising benzimidazole compound and strong alkali |
MY137726A (en) | 2000-11-22 | 2009-03-31 | Nycomed Gmbh | Freeze-dried pantoprazole preparation and pantoprazole injection |
AR045258A1 (es) | 2003-08-21 | 2005-10-19 | Altana Pharma Ag | Un producto farmaceutico para inyeccion |
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2001
- 2001-10-19 MY MYPI20014865A patent/MY137726A/en unknown
- 2001-11-06 TW TW090127545A patent/TWI284041B/zh not_active IP Right Cessation
- 2001-11-17 ME MEP-696/08A patent/ME00556A/xx unknown
- 2001-11-17 SK SK606-2003A patent/SK287993B6/sk not_active IP Right Cessation
- 2001-11-17 WO PCT/EP2001/013296 patent/WO2002041919A1/en active IP Right Grant
- 2001-11-17 EE EEP200300182A patent/EE05236B1/xx not_active IP Right Cessation
- 2001-11-17 RS YU37703A patent/RS52024B/sr unknown
- 2001-11-17 SI SI200130816T patent/SI1339430T1/sl unknown
- 2001-11-17 EP EP01997314A patent/EP1339430B1/en not_active Revoked
- 2001-11-17 PT PT01997314T patent/PT1339430E/pt unknown
- 2001-11-17 BR BRPI0115483A patent/BRPI0115483B8/pt not_active IP Right Cessation
- 2001-11-17 CN CNB01819379XA patent/CN1250292C/zh not_active Expired - Lifetime
- 2001-11-17 DK DK01997314T patent/DK1339430T3/da active
- 2001-11-17 AU AU1604202A patent/AU1604202A/xx active Pending
- 2001-11-17 GE GE5180A patent/GEP20053461B/en unknown
- 2001-11-17 NZ NZ525911A patent/NZ525911A/en not_active IP Right Cessation
- 2001-11-17 AU AU2002216042A patent/AU2002216042B2/en not_active Expired
- 2001-11-17 KR KR1020037006675A patent/KR100910606B1/ko active IP Right Grant
- 2001-11-17 MX MXPA03004548A patent/MXPA03004548A/es active IP Right Grant
- 2001-11-17 IL IL15560101A patent/IL155601A0/xx unknown
- 2001-11-17 CA CA002541946A patent/CA2541946A1/en not_active Abandoned
- 2001-11-17 CA CA002428870A patent/CA2428870C/en not_active Expired - Lifetime
- 2001-11-17 UA UA20040705223A patent/UA80961C2/uk unknown
- 2001-11-17 CZ CZ2003-1416A patent/CZ304348B6/cs not_active IP Right Cessation
- 2001-11-17 EP EP06123558.6A patent/EP1762249A3/en not_active Ceased
- 2001-11-17 AT AT01997314T patent/ATE381946T1/de active
- 2001-11-17 DE DE60132108T patent/DE60132108T2/de not_active Expired - Lifetime
- 2001-11-17 KR KR1020077027736A patent/KR100910607B1/ko active IP Right Grant
- 2001-11-17 PL PL361118A patent/PL201188B1/pl unknown
- 2001-11-17 JP JP2002544096A patent/JP4886158B2/ja not_active Expired - Fee Related
- 2001-11-17 HU HU0303278A patent/HUP0303278A3/hu unknown
- 2001-11-17 ES ES01997314T patent/ES2298295T3/es not_active Expired - Lifetime
- 2001-11-17 EA EA200300501A patent/EA007602B1/ru not_active IP Right Cessation
- 2001-11-19 PE PE2001001153A patent/PE20020582A1/es active IP Right Grant
- 2001-11-19 AR ARP010105391A patent/AR034277A1/es not_active Application Discontinuation
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2002
- 2002-07-15 US US10/195,062 patent/US6780881B2/en not_active Expired - Lifetime
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2003
- 2003-04-28 IL IL155601A patent/IL155601A/en active IP Right Grant
- 2003-05-09 ZA ZA200303593A patent/ZA200303593B/en unknown
- 2003-05-19 IS IS6820A patent/IS2971B/is unknown
- 2003-05-19 EC EC2003004613A patent/ECSP034613A/es unknown
- 2003-05-20 BG BG107828A patent/BG66329B1/bg unknown
- 2003-05-21 NO NO20032303A patent/NO332937B1/no not_active IP Right Cessation
- 2003-05-21 HR HR20030410A patent/HRP20030410B1/xx not_active IP Right Cessation
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2004
- 2004-05-28 US US10/855,703 patent/US7351723B2/en not_active Expired - Lifetime
- 2004-05-28 HK HK04103845A patent/HK1060848A1/xx not_active IP Right Cessation
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2008
- 2008-01-22 US US12/010,124 patent/US8754108B2/en not_active Expired - Lifetime
- 2008-02-28 CY CY20081100226T patent/CY1107896T1/el unknown
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2013
- 2013-08-21 AR ARP130102967A patent/AR092374A2/es not_active Application Discontinuation
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