BRPI0115483B8 - preparação de pantoprazol seco por congelação e injeção de pantoprazol - Google Patents
preparação de pantoprazol seco por congelação e injeção de pantoprazolInfo
- Publication number
- BRPI0115483B8 BRPI0115483B8 BRPI0115483A BR0115483A BRPI0115483B8 BR PI0115483 B8 BRPI0115483 B8 BR PI0115483B8 BR PI0115483 A BRPI0115483 A BR PI0115483A BR 0115483 A BR0115483 A BR 0115483A BR PI0115483 B8 BRPI0115483 B8 BR PI0115483B8
- Authority
- BR
- Brazil
- Prior art keywords
- pantoprazole
- injection
- freeze
- dried
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00125569 | 2000-11-22 | ||
PCT/EP2001/013296 WO2002041919A1 (en) | 2000-11-22 | 2001-11-17 | Freeze-dried pantoprazole preparation and pantoprazole injection |
Publications (3)
Publication Number | Publication Date |
---|---|
BR0115483A BR0115483A (pt) | 2003-10-21 |
BRPI0115483B1 BRPI0115483B1 (pt) | 2017-05-09 |
BRPI0115483B8 true BRPI0115483B8 (pt) | 2021-05-25 |
Family
ID=8170452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0115483A BRPI0115483B8 (pt) | 2000-11-22 | 2001-11-17 | preparação de pantoprazol seco por congelação e injeção de pantoprazol |
Country Status (40)
Country | Link |
---|---|
US (3) | US6780881B2 (pt) |
EP (2) | EP1339430B1 (pt) |
JP (1) | JP4886158B2 (pt) |
KR (2) | KR100910607B1 (pt) |
CN (1) | CN1250292C (pt) |
AR (2) | AR034277A1 (pt) |
AT (1) | ATE381946T1 (pt) |
AU (2) | AU1604202A (pt) |
BG (1) | BG66329B1 (pt) |
BR (1) | BRPI0115483B8 (pt) |
CA (2) | CA2428870C (pt) |
CY (1) | CY1107896T1 (pt) |
CZ (1) | CZ304348B6 (pt) |
DE (1) | DE60132108T2 (pt) |
DK (1) | DK1339430T3 (pt) |
EA (1) | EA007602B1 (pt) |
EC (1) | ECSP034613A (pt) |
EE (1) | EE05236B1 (pt) |
ES (1) | ES2298295T3 (pt) |
GE (1) | GEP20053461B (pt) |
HK (1) | HK1060848A1 (pt) |
HR (1) | HRP20030410B1 (pt) |
HU (1) | HUP0303278A3 (pt) |
IL (2) | IL155601A0 (pt) |
IS (1) | IS2971B (pt) |
ME (1) | ME00556B (pt) |
MX (1) | MXPA03004548A (pt) |
MY (1) | MY137726A (pt) |
NO (1) | NO332937B1 (pt) |
NZ (1) | NZ525911A (pt) |
PE (1) | PE20020582A1 (pt) |
PL (1) | PL201188B1 (pt) |
PT (1) | PT1339430E (pt) |
RS (1) | RS52024B (pt) |
SI (1) | SI1339430T1 (pt) |
SK (1) | SK287993B6 (pt) |
TW (1) | TWI284041B (pt) |
UA (1) | UA80961C2 (pt) |
WO (1) | WO2002041919A1 (pt) |
ZA (1) | ZA200303593B (pt) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY137726A (en) * | 2000-11-22 | 2009-03-31 | Nycomed Gmbh | Freeze-dried pantoprazole preparation and pantoprazole injection |
US20050287231A1 (en) * | 2002-06-21 | 2005-12-29 | Nussen Kenneth H | Method and apparatus for oral hygiene products with green tea extract |
KR20050071611A (ko) * | 2002-10-25 | 2005-07-07 | 화이자 프로덕츠 인코포레이티드 | 현탁액 형태의 아릴헤테로환 활성제의 저장 제형 |
AU2003241150A1 (en) * | 2003-05-06 | 2004-11-26 | Hetero Drugs Limited | Novel polymorphs of pantoprazole sodium |
CL2004000983A1 (es) * | 2003-05-08 | 2005-03-04 | Altana Pharma Ag | Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y |
US20050004172A1 (en) * | 2003-05-19 | 2005-01-06 | Pliva-Istrazivacki Institut D.O.O. | Solid state forms of 5-(difluoro-methoxy)-2-((3,4-dimethoxy-2-pyridinyl)-methyl) sulfinyl]-1H-benzimidazole sodium aquo complexes |
AR045258A1 (es) * | 2003-08-21 | 2005-10-19 | Altana Pharma Ag | Un producto farmaceutico para inyeccion |
WO2005070426A1 (en) * | 2004-01-27 | 2005-08-04 | Altana Pharma Ag | Freeze-dried (-)-pantoprazole preparation and (-)-pantoprazole injection |
DE102004007854A1 (de) * | 2004-02-17 | 2005-09-01 | Hexal Ag | Stabile, wässrige Formulierung für Benzimidazole |
US20060085924A1 (en) * | 2004-10-13 | 2006-04-27 | Gaelle Brun | Coloring composition comprising at least one pigment and at least one electrophilic cyanoacrylate monomer |
CN1293879C (zh) * | 2005-01-20 | 2007-01-10 | 杭州华东医药集团生物工程研究所有限公司 | 泮托拉唑钠冻干粉针剂及其制备方法 |
JP2009511481A (ja) * | 2005-10-06 | 2009-03-19 | オースペックス・ファーマシューティカルズ・インコーポレイテッド | 増強された治療特性を持つ、胃H+,K+−ATPaseの重水素化阻害剤 |
WO2009001163A1 (en) * | 2006-06-01 | 2008-12-31 | Combino Pharm, S.L. | Lyophilized preparations of pantoprazole sodium for injection |
US8232245B2 (en) | 2006-07-26 | 2012-07-31 | Sandoz Ag | Caspofungin formulations |
US7979200B2 (en) * | 2006-11-20 | 2011-07-12 | Lockheed Martin Corporation | Managing an air-ground communications network with air traffic control information |
EP2106788A1 (en) * | 2008-04-04 | 2009-10-07 | Ipsen Pharma | Liquid and freeze dried formulations |
CN101744777B (zh) * | 2009-12-30 | 2012-09-26 | 北京四环科宝制药有限公司 | 奥美拉唑钠冻干粉针剂及制备方法和检测方法 |
CN101961309B (zh) * | 2010-09-15 | 2012-06-27 | 河南辅仁怀庆堂制药有限公司 | 注射用泮托拉唑钠配制工艺 |
CN102000034B (zh) * | 2010-10-13 | 2011-12-21 | 江苏奥赛康药业股份有限公司 | 一种供注射用的s-泮托拉唑钠组合物及其制备方法 |
CN102225063B (zh) * | 2011-05-10 | 2012-10-10 | 江苏奥赛康药业股份有限公司 | 一种供注射用的泮托拉唑钠组合物 |
TR201108946A2 (tr) * | 2011-09-12 | 2012-04-24 | World Medicine İlaç Sanayi̇ Ve Ti̇caret Li̇mi̇ted Şi̇rketi̇ | Dondurularak kurutulmuş atp, vitamin b kompleksi preparatı ve enjeksiyonu. |
WO2014003199A1 (en) * | 2012-06-27 | 2014-01-03 | Takeda Pharmaceutical Company Limited | Liquid preparations of amines and organic acids stabilized by salts |
CN104000786A (zh) * | 2013-02-25 | 2014-08-27 | 杭州赛利药物研究所有限公司 | 泮托拉唑钠冻干制剂及其制备方法 |
CN104414979A (zh) * | 2013-08-21 | 2015-03-18 | 哈药集团三精制药股份有限公司 | 一种泮托拉唑钠冻干粉针剂及其制备方法 |
CN104019635B (zh) * | 2014-06-19 | 2015-05-27 | 上海慈瑞医药科技有限公司 | 一种兰索拉唑原料药化合物及其干燥工艺 |
CN104055791A (zh) * | 2014-07-10 | 2014-09-24 | 北京人福军威医药技术开发有限公司 | 西地碘治疗眼角结膜炎的用途 |
CN104055792A (zh) * | 2014-07-10 | 2014-09-24 | 北京人福军威医药技术开发有限公司 | 西地碘治疗中耳炎的用途 |
BE1021311B1 (nl) * | 2014-07-31 | 2015-10-28 | Neogen N.V. | Werkwijze voor het maken van een poedervormige protonpompremmer samenstelling, genoemde samenstelling en gebruik |
EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
CN111643460A (zh) * | 2020-06-30 | 2020-09-11 | 武汉九州钰民医药科技有限公司 | 泮托拉唑钠冻干制剂及其制备方法、由其制得的注射制剂 |
CN112274481A (zh) * | 2020-10-27 | 2021-01-29 | 海南卫康制药(潜山)有限公司 | 一种注射用泮托拉唑钠组合物及其制备方法 |
Family Cites Families (21)
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SE8301182D0 (sv) | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
IL75400A (en) * | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
US5223515A (en) | 1988-08-18 | 1993-06-29 | Takeda Chemical Industries, Ltd. | Injectable solution containing a pyridyl methylsulfinylbenzimidazole |
DK399389A (da) | 1988-08-18 | 1990-02-19 | Takeda Chemical Industries Ltd | Injicerbare oploesninger |
DE4035455A1 (de) | 1990-11-08 | 1992-05-14 | Byk Gulden Lomberg Chem Fab | Enantiomerentrennung |
NZ254237A (en) | 1992-07-28 | 1995-12-21 | Astra Ab | Injectable solution of a 2-[(2-pyridyl)methylsulphinyl]-benzimidazole or a salt thereof; an injection kit |
JPH08509736A (ja) | 1993-04-27 | 1996-10-15 | セプラコー,インコーポレイテッド | 光学的に純粋な(−)パントプラゾールを用いる胃の疾患治療の方法と組成 |
DE4324014C2 (de) | 1993-07-17 | 1995-06-08 | Byk Gulden Lomberg Chem Fab | Verfahren zur Herstellung einer in Wasser rekonstituierbaren Zubereitung |
TW280770B (pt) | 1993-10-15 | 1996-07-11 | Takeda Pharm Industry Co Ltd | |
HU224987B1 (en) | 1995-11-03 | 2006-05-29 | Sanofi Aventis | Stable freeze-dried pharmaceutical formulation |
FR2740686B1 (fr) | 1995-11-03 | 1998-01-16 | Sanofi Sa | Formulation pharmaceutique lyophilisee stable |
US5980882A (en) * | 1997-04-16 | 1999-11-09 | Medeva Pharmaceuticals Manufacturing | Drug-resin complexes stabilized by chelating agents |
CA2308143A1 (en) | 1997-10-14 | 1999-04-22 | Eisai Co., Ltd. | Pharmaceutical formulation comprising glycine as a stabilizer |
DE19843413C1 (de) * | 1998-08-18 | 2000-03-30 | Byk Gulden Lomberg Chem Fab | Neue Salzform von Pantoprazol |
WO2000026185A2 (en) | 1998-10-30 | 2000-05-11 | The Curators Of The University Of Missouri | Omeprazole solution and method of using same |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
CN1235018A (zh) * | 1999-04-22 | 1999-11-17 | 沈阳东宇药业有限公司 | 泮托拉唑钠冻干粉针剂及制备方法 |
SE9903831D0 (sv) * | 1999-10-22 | 1999-10-22 | Astra Ab | Formulation of substituted benzimidazoles |
WO2002015908A1 (fr) * | 2000-08-18 | 2002-02-28 | Takeda Chemical Industries, Ltd. | Injections |
MY137726A (en) * | 2000-11-22 | 2009-03-31 | Nycomed Gmbh | Freeze-dried pantoprazole preparation and pantoprazole injection |
AR045258A1 (es) | 2003-08-21 | 2005-10-19 | Altana Pharma Ag | Un producto farmaceutico para inyeccion |
-
2001
- 2001-10-19 MY MYPI20014865A patent/MY137726A/en unknown
- 2001-11-06 TW TW090127545A patent/TWI284041B/zh not_active IP Right Cessation
- 2001-11-17 NZ NZ525911A patent/NZ525911A/en not_active IP Right Cessation
- 2001-11-17 PL PL361118A patent/PL201188B1/pl unknown
- 2001-11-17 EP EP01997314A patent/EP1339430B1/en not_active Revoked
- 2001-11-17 EP EP06123558.6A patent/EP1762249A3/en not_active Ceased
- 2001-11-17 EE EEP200300182A patent/EE05236B1/xx not_active IP Right Cessation
- 2001-11-17 CA CA002428870A patent/CA2428870C/en not_active Expired - Lifetime
- 2001-11-17 PT PT01997314T patent/PT1339430E/pt unknown
- 2001-11-17 SK SK606-2003A patent/SK287993B6/sk not_active IP Right Cessation
- 2001-11-17 SI SI200130816T patent/SI1339430T1/sl unknown
- 2001-11-17 IL IL15560101A patent/IL155601A0/xx unknown
- 2001-11-17 KR KR1020077027736A patent/KR100910607B1/ko active IP Right Grant
- 2001-11-17 AU AU1604202A patent/AU1604202A/xx active Pending
- 2001-11-17 GE GE5180A patent/GEP20053461B/en unknown
- 2001-11-17 RS YU37703A patent/RS52024B/sr unknown
- 2001-11-17 JP JP2002544096A patent/JP4886158B2/ja not_active Expired - Fee Related
- 2001-11-17 DE DE60132108T patent/DE60132108T2/de not_active Expired - Lifetime
- 2001-11-17 ME MEP-2008-696A patent/ME00556B/me unknown
- 2001-11-17 ES ES01997314T patent/ES2298295T3/es not_active Expired - Lifetime
- 2001-11-17 MX MXPA03004548A patent/MXPA03004548A/es active IP Right Grant
- 2001-11-17 CA CA002541946A patent/CA2541946A1/en not_active Abandoned
- 2001-11-17 CZ CZ2003-1416A patent/CZ304348B6/cs not_active IP Right Cessation
- 2001-11-17 HU HU0303278A patent/HUP0303278A3/hu unknown
- 2001-11-17 KR KR1020037006675A patent/KR100910606B1/ko active IP Right Grant
- 2001-11-17 WO PCT/EP2001/013296 patent/WO2002041919A1/en active IP Right Grant
- 2001-11-17 BR BRPI0115483A patent/BRPI0115483B8/pt not_active IP Right Cessation
- 2001-11-17 AU AU2002216042A patent/AU2002216042B2/en not_active Expired
- 2001-11-17 DK DK01997314T patent/DK1339430T3/da active
- 2001-11-17 UA UA20040705223A patent/UA80961C2/uk unknown
- 2001-11-17 AT AT01997314T patent/ATE381946T1/de active
- 2001-11-17 EA EA200300501A patent/EA007602B1/ru not_active IP Right Cessation
- 2001-11-17 CN CNB01819379XA patent/CN1250292C/zh not_active Expired - Lifetime
- 2001-11-19 AR ARP010105391A patent/AR034277A1/es not_active Application Discontinuation
- 2001-11-19 PE PE2001001153A patent/PE20020582A1/es active IP Right Grant
-
2002
- 2002-07-15 US US10/195,062 patent/US6780881B2/en not_active Expired - Lifetime
-
2003
- 2003-04-28 IL IL155601A patent/IL155601A/en active IP Right Grant
- 2003-05-09 ZA ZA200303593A patent/ZA200303593B/en unknown
- 2003-05-19 EC EC2003004613A patent/ECSP034613A/es unknown
- 2003-05-19 IS IS6820A patent/IS2971B/is unknown
- 2003-05-20 BG BG107828A patent/BG66329B1/bg unknown
- 2003-05-21 HR HR20030410A patent/HRP20030410B1/xx not_active IP Right Cessation
- 2003-05-21 NO NO20032303A patent/NO332937B1/no not_active IP Right Cessation
-
2004
- 2004-05-28 HK HK04103845A patent/HK1060848A1/xx not_active IP Right Cessation
- 2004-05-28 US US10/855,703 patent/US7351723B2/en not_active Expired - Lifetime
-
2008
- 2008-01-22 US US12/010,124 patent/US8754108B2/en not_active Expired - Lifetime
- 2008-02-28 CY CY20081100226T patent/CY1107896T1/el unknown
-
2013
- 2013-08-21 AR ARP130102967A patent/AR092374A2/es not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: NYCOMED GMBH (DE) Free format text: ALTERADO DE: ALTANA PHARMA AG |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B25D | Requested change of name of applicant approved |
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