PE20020582A1 - Preparacion liofilizada de pantoprazol e inyeccion de pantoprazol - Google Patents

Preparacion liofilizada de pantoprazol e inyeccion de pantoprazol

Info

Publication number
PE20020582A1
PE20020582A1 PE2001001153A PE2001001153A PE20020582A1 PE 20020582 A1 PE20020582 A1 PE 20020582A1 PE 2001001153 A PE2001001153 A PE 2001001153A PE 2001001153 A PE2001001153 A PE 2001001153A PE 20020582 A1 PE20020582 A1 PE 20020582A1
Authority
PE
Peru
Prior art keywords
pantoprazole
lyophilized preparation
injection
refers
sodium
Prior art date
Application number
PE2001001153A
Other languages
English (en)
Inventor
Rudolf Linder
Rango Dietrich
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8170452&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20020582(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of PE20020582A1 publication Critical patent/PE20020582A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SE REFIERE A UN PROCESO PARA LA PREPARACION LIOFILIZADA DE 5-DIFLUOROMETOXI-2-[(3,4-DIMETOXI-2-PIRIDINIL)-METILSULFINIL]-1H-BENCIMIDAZOL (PANTOPRAZOL) QUE COMPRENDE LIOFILIZAR UNA SOLUCION ACUOSA DE 0,05% A 25% DE SESQUIHIDRATO DE PANTOPRAZOL DE SODIO, ACIDO ETILENDIAMINOTETRAACETICO; HIDROXIDO DE SODIO Y CARBONATO DE SODIO; CON UN pH DE 8 O SUPERIOR A 8; TAMBIEN SE REFIERE A UNA PREPARACION LIOFILIZADA DE PANTOPRAZOL DE PREFERENCIA UN INYECTABLE QUE TIENE MENOS DE 120 PARTICULAS SUBVISIBLES POR VIAL, CON UN TAMANO DE PARTICULAS IGUAL O MAYOR DE 10µm. LA COMPOSICION SE CARACTERIZA POR TENER PROPIEDADES VENTAJOSAS CUANDO SE RECONSTITUYEN.
PE2001001153A 2000-11-22 2001-11-19 Preparacion liofilizada de pantoprazol e inyeccion de pantoprazol PE20020582A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00125569 2000-11-22

Publications (1)

Publication Number Publication Date
PE20020582A1 true PE20020582A1 (es) 2002-07-06

Family

ID=8170452

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2001001153A PE20020582A1 (es) 2000-11-22 2001-11-19 Preparacion liofilizada de pantoprazol e inyeccion de pantoprazol

Country Status (40)

Country Link
US (3) US6780881B2 (es)
EP (2) EP1339430B1 (es)
JP (1) JP4886158B2 (es)
KR (2) KR100910606B1 (es)
CN (1) CN1250292C (es)
AR (2) AR034277A1 (es)
AT (1) ATE381946T1 (es)
AU (2) AU2002216042B2 (es)
BG (1) BG66329B1 (es)
BR (1) BRPI0115483B8 (es)
CA (2) CA2428870C (es)
CY (1) CY1107896T1 (es)
CZ (1) CZ304348B6 (es)
DE (1) DE60132108T2 (es)
DK (1) DK1339430T3 (es)
EA (1) EA007602B1 (es)
EC (1) ECSP034613A (es)
EE (1) EE05236B1 (es)
ES (1) ES2298295T3 (es)
GE (1) GEP20053461B (es)
HK (1) HK1060848A1 (es)
HR (1) HRP20030410B1 (es)
HU (1) HUP0303278A3 (es)
IL (2) IL155601A0 (es)
IS (1) IS2971B (es)
ME (1) ME00556B (es)
MX (1) MXPA03004548A (es)
MY (1) MY137726A (es)
NO (1) NO332937B1 (es)
NZ (1) NZ525911A (es)
PE (1) PE20020582A1 (es)
PL (1) PL201188B1 (es)
PT (1) PT1339430E (es)
RS (1) RS52024B (es)
SI (1) SI1339430T1 (es)
SK (1) SK287993B6 (es)
TW (1) TWI284041B (es)
UA (1) UA80961C2 (es)
WO (1) WO2002041919A1 (es)
ZA (1) ZA200303593B (es)

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AU2003241150A1 (en) * 2003-05-06 2004-11-26 Hetero Drugs Limited Novel polymorphs of pantoprazole sodium
CL2004000983A1 (es) * 2003-05-08 2005-03-04 Altana Pharma Ag Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y
EP1631284A2 (en) * 2003-05-19 2006-03-08 Pliva-Istrazivanje I Razvoj D.D.O. Solid-state forms of 5-(difluoromethoxy)-2-((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-1h-benzimidazole (pantoprazole) sodium aqua complexes
AR045258A1 (es) * 2003-08-21 2005-10-19 Altana Pharma Ag Un producto farmaceutico para inyeccion
WO2005070426A1 (en) * 2004-01-27 2005-08-04 Altana Pharma Ag Freeze-dried (-)-pantoprazole preparation and (-)-pantoprazole injection
DE102004007854A1 (de) * 2004-02-17 2005-09-01 Hexal Ag Stabile, wässrige Formulierung für Benzimidazole
US20060085924A1 (en) * 2004-10-13 2006-04-27 Gaelle Brun Coloring composition comprising at least one pigment and at least one electrophilic cyanoacrylate monomer
CN1293879C (zh) * 2005-01-20 2007-01-10 杭州华东医药集团生物工程研究所有限公司 泮托拉唑钠冻干粉针剂及其制备方法
US7598273B2 (en) * 2005-10-06 2009-10-06 Auspex Pharmaceuticals, Inc Inhibitors of the gastric H+, K+-ATPase with enhanced therapeutic properties
AR061155A1 (es) * 2006-06-01 2008-08-06 Combino Pharm Sl Preparaciones liofilizadas de pantoprazol sodico para inyeccion
BRPI0715113A2 (pt) 2006-07-26 2013-06-04 Sandoz Ag Sandoz Sa Sandoz Ltd formulaÇço de caspofungina
US7979200B2 (en) * 2006-11-20 2011-07-12 Lockheed Martin Corporation Managing an air-ground communications network with air traffic control information
EP2106788A1 (en) * 2008-04-04 2009-10-07 Ipsen Pharma Liquid and freeze dried formulations
CN101744777B (zh) * 2009-12-30 2012-09-26 北京四环科宝制药有限公司 奥美拉唑钠冻干粉针剂及制备方法和检测方法
CN101961309B (zh) * 2010-09-15 2012-06-27 河南辅仁怀庆堂制药有限公司 注射用泮托拉唑钠配制工艺
CN102000034B (zh) * 2010-10-13 2011-12-21 江苏奥赛康药业股份有限公司 一种供注射用的s-泮托拉唑钠组合物及其制备方法
CN102225063B (zh) * 2011-05-10 2012-10-10 江苏奥赛康药业股份有限公司 一种供注射用的泮托拉唑钠组合物
TR201108946A2 (tr) * 2011-09-12 2012-04-24 World Medicine İlaç Sanayi̇ Ve Ti̇caret Li̇mi̇ted Şi̇rketi̇ Dondurularak kurutulmuş atp, vitamin b kompleksi preparatı ve enjeksiyonu.
NZ703528A (en) * 2012-06-27 2016-08-26 Takeda Pharmaceutical Liquid preparations of amines and organic acids stabilized by salts
CN104000786A (zh) * 2013-02-25 2014-08-27 杭州赛利药物研究所有限公司 泮托拉唑钠冻干制剂及其制备方法
CN104414979A (zh) * 2013-08-21 2015-03-18 哈药集团三精制药股份有限公司 一种泮托拉唑钠冻干粉针剂及其制备方法
CN104019635B (zh) * 2014-06-19 2015-05-27 上海慈瑞医药科技有限公司 一种兰索拉唑原料药化合物及其干燥工艺
CN104055792A (zh) * 2014-07-10 2014-09-24 北京人福军威医药技术开发有限公司 西地碘治疗中耳炎的用途
CN104055791A (zh) * 2014-07-10 2014-09-24 北京人福军威医药技术开发有限公司 西地碘治疗眼角结膜炎的用途
BE1021311B1 (nl) * 2014-07-31 2015-10-28 Neogen N.V. Werkwijze voor het maken van een poedervormige protonpompremmer samenstelling, genoemde samenstelling en gebruik
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
CN111643460A (zh) * 2020-06-30 2020-09-11 武汉九州钰民医药科技有限公司 泮托拉唑钠冻干制剂及其制备方法、由其制得的注射制剂
CN112274481A (zh) * 2020-10-27 2021-01-29 海南卫康制药(潜山)有限公司 一种注射用泮托拉唑钠组合物及其制备方法

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Also Published As

Publication number Publication date
JP4886158B2 (ja) 2012-02-29
EA007602B1 (ru) 2006-12-29
MXPA03004548A (es) 2003-09-10
KR100910606B1 (ko) 2009-08-04
CZ20031416A3 (cs) 2003-09-17
US7351723B2 (en) 2008-04-01
HUP0303278A3 (en) 2007-08-28
EP1762249A2 (en) 2007-03-14
EP1339430A1 (en) 2003-09-03
US6780881B2 (en) 2004-08-24
PL201188B1 (pl) 2009-03-31
HUP0303278A2 (hu) 2004-01-28
US20030003058A1 (en) 2003-01-02
EE05236B1 (et) 2009-12-15
NO20032303D0 (no) 2003-05-21
IS2971B (is) 2017-05-15
RS52024B (sr) 2012-04-30
JP2004513970A (ja) 2004-05-13
US8754108B2 (en) 2014-06-17
NO332937B1 (no) 2013-02-04
CA2541946A1 (en) 2002-05-30
MY137726A (en) 2009-03-31
EP1339430B1 (en) 2007-12-26
BRPI0115483B8 (pt) 2021-05-25
US20090093522A1 (en) 2009-04-09
CN1476335A (zh) 2004-02-18
PL361118A1 (en) 2004-09-20
HRP20030410B1 (en) 2011-02-28
BG66329B1 (bg) 2013-06-28
NZ525911A (en) 2004-11-26
PT1339430E (pt) 2008-03-27
EA200300501A1 (ru) 2003-12-25
ES2298295T3 (es) 2008-05-16
ME00556A (en) 2011-12-20
SI1339430T1 (sl) 2008-06-30
SK287993B6 (sk) 2012-09-03
CY1107896T1 (el) 2013-09-04
SK6062003A3 (en) 2003-10-07
ME00556B (me) 2011-12-20
EP1762249A3 (en) 2014-05-14
DE60132108T2 (de) 2008-12-11
KR100910607B1 (ko) 2009-08-04
KR20080003010A (ko) 2008-01-04
TWI284041B (en) 2007-07-21
IL155601A (en) 2008-12-29
IL155601A0 (en) 2003-11-23
EE200300182A (et) 2003-06-16
YU37703A (sh) 2006-05-25
BG107828A (bg) 2004-07-30
HK1060848A1 (en) 2004-08-27
IS6820A (is) 2003-05-19
HRP20030410A2 (en) 2005-04-30
CZ304348B6 (cs) 2014-03-19
GEP20053461B (en) 2005-02-25
UA80961C2 (en) 2007-11-26
ECSP034613A (es) 2003-08-29
CA2428870A1 (en) 2002-05-30
WO2002041919A1 (en) 2002-05-30
AU1604202A (en) 2002-06-03
CA2428870C (en) 2006-05-23
BR0115483A (pt) 2003-10-21
NO20032303L (no) 2003-05-21
AR034277A1 (es) 2004-02-18
US20040220228A1 (en) 2004-11-04
CN1250292C (zh) 2006-04-12
BRPI0115483B1 (pt) 2017-05-09
DE60132108D1 (de) 2008-02-07
DK1339430T3 (da) 2008-05-13
ZA200303593B (en) 2004-04-23
AU2002216042B2 (en) 2006-08-03
ATE381946T1 (de) 2008-01-15
AR092374A2 (es) 2015-04-15
KR20030055308A (ko) 2003-07-02

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