BR0115326A - Compostos dehalogenados - Google Patents

Compostos dehalogenados

Info

Publication number
BR0115326A
BR0115326A BR0115326-9A BR0115326A BR0115326A BR 0115326 A BR0115326 A BR 0115326A BR 0115326 A BR0115326 A BR 0115326A BR 0115326 A BR0115326 A BR 0115326A
Authority
BR
Brazil
Prior art keywords
compounds
dehalogenated
substituted
gram positive
halogenated compounds
Prior art date
Application number
BR0115326-9A
Other languages
English (en)
Inventor
Hisashi Takahashi
Rie Miyauchi
Masao Itoh
Makoto Takemura
Isao Hayakawa
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of BR0115326A publication Critical patent/BR0115326A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

"COMPOSTOS DEHALOGENADOS". Derivados de ácido de quinolona substituída com hidrogênio 6-dehalogenada substituída com 3- (1-amino ciclo-alquil) pirrolidinil carboxílico tendo substituintes específicos como representado pela seguinte fórmula (I) , sais dos mesmos e hidratos dos mesmos, apresentam uma ampla e potente atividade antibacteriana sobre bactérias gram positivo e gram negativo, em particular, bactérias resistentes como por exemplo, cocus gram positivo incluindo MRSA, PRSP e VRE. Assim, esses compostos são usáveis como drogas.
BR0115326-9A 2000-11-20 2001-11-19 Compostos dehalogenados BR0115326A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000352269 2000-11-20
JP2001248822 2001-08-20
PCT/JP2001/010086 WO2002040478A1 (fr) 2000-11-20 2001-11-19 Composes dihalogenes

Publications (1)

Publication Number Publication Date
BR0115326A true BR0115326A (pt) 2004-02-25

Family

ID=26604261

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0115326-9A BR0115326A (pt) 2000-11-20 2001-11-19 Compostos dehalogenados

Country Status (20)

Country Link
US (2) US20040063754A1 (pt)
EP (1) EP1336611B1 (pt)
JP (3) JP3711108B2 (pt)
KR (1) KR100777149B1 (pt)
CN (1) CN1269817C (pt)
AR (1) AR035599A1 (pt)
AT (1) ATE372338T1 (pt)
AU (1) AU2405002A (pt)
BR (1) BR0115326A (pt)
CA (1) CA2429440C (pt)
DE (1) DE60130359T2 (pt)
ES (1) ES2292642T3 (pt)
HK (1) HK1056729A1 (pt)
IL (2) IL155976A0 (pt)
MX (1) MXPA03004437A (pt)
MY (1) MY136916A (pt)
NO (1) NO326157B1 (pt)
PT (1) PT1336611E (pt)
TW (1) TWI315308B (pt)
WO (1) WO2002040478A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0115326A (pt) 2000-11-20 2004-02-25 Daiichi Seiyaku Co Compostos dehalogenados
US7915418B2 (en) 2003-06-06 2011-03-29 Daiichi Pharmaceutical Co., Ltd. Intermediates and process for the production of optically active quinolonecarboxylic acid derivatives
WO2004113321A1 (ja) * 2003-06-19 2004-12-29 Daiichi Pharmaceutical Co., Ltd. 選択的なアミノ置換基導入法
JP4629973B2 (ja) * 2003-09-22 2011-02-09 第一三共株式会社 光学活性シクロプロピルアミン誘導体およびその製造方法
EP1669354B1 (en) * 2003-09-29 2013-03-20 Daiichi Sankyo Company, Limited 8-cyanoquinolonecarboxylic acid derivative
US7569599B2 (en) 2003-12-12 2009-08-04 Daiichi Pharmaceutical Co., Ltd. Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates
ZA200700844B (en) * 2004-07-02 2009-07-29 Daiichi Seiyaku Co Quinolone-containing medicinal composition
JPWO2007037330A1 (ja) 2005-09-28 2009-04-09 第一三共株式会社 キノロン含有凍結乾燥製剤の製造方法
CN100441580C (zh) * 2006-07-14 2008-12-10 中山大学 喹啉二酮衍生物及其在制备抗菌药物中的应用
DK2057185T3 (en) * 2006-08-11 2016-06-13 Northern Antibiotics Oy POLYMYXIN DERIVATIVES AND APPLICATIONS THEREOF
JP5174365B2 (ja) * 2007-03-23 2013-04-03 第一三共株式会社 キノロン含有凍結乾燥製剤の製造方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0207420B1 (en) * 1985-06-26 1992-05-06 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives
WO1996012704A1 (fr) 1994-10-20 1996-05-02 Wakunaga Seiyaku Kabushiki Kaisha Nouveau derive de pyridone-carboxylate, ou sel de celui-ci, et antibacterien le contenant comme principe actif
US5849757A (en) * 1995-02-02 1998-12-15 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials
RU2177945C1 (ru) 1995-09-22 2002-01-10 Вакунага Фармасьютикал КО., Лтд. Производное пиридонкарбоновой кислоты или его соль
KR19990071558A (ko) 1995-11-22 1999-09-27 스즈키 다다시 치환된 아미노시클로알킬피롤리딘 유도체
US6121285A (en) * 1995-11-22 2000-09-19 Daiichi Pharmaceutical Co., Ltd. Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives
DE69732635T2 (de) 1996-07-12 2005-12-29 Daiichi Pharmaceutical Co., Ltd. Cis-substituierte aminocyclopropanderivate
JPH1081682A (ja) 1996-07-12 1998-03-31 Dai Ichi Seiyaku Co Ltd シス置換アミノシクロプロパン誘導体
TW519542B (en) * 1996-09-27 2003-02-01 Daiichi Seiyaku Co Bicyclic amine derivative
CA2289605A1 (en) 1997-05-21 1998-11-26 Daiichi Pharmaceutical Co., Ltd. Cis-substituted substituted aminocycloalkylpyrrolidine derivatives
ZA984527B (en) 1997-05-30 1998-12-03 Daiichi Seiyaku Co Substituted cyclobutylamine derivative
KR20010014209A (ko) * 1997-06-24 2001-02-26 스즈키 다다시 시스-치환된 플루오로메틸피롤리딘 유도체
TR200001435T2 (tr) * 1997-09-15 2000-08-21 The Procter & Gamble Company Antimikrobiyal kuinolonlar, bunların bileşimleri ve kullanımları
JP2000023709A (ja) * 1998-07-16 2000-01-25 Shimano Inc 長 靴
DE19834202A1 (de) 1998-07-29 2000-02-10 Coherent Luebeck Gmbh Rauscharmer frequenzvervielfachter Laser mit Strahlseparator
EP1134219B1 (en) 1998-11-24 2005-06-15 Daiichi Pharmaceutical Co., Ltd. Cycloalkyl-substituted aminomethylpyrrolidine derivatives
BR0115326A (pt) 2000-11-20 2004-02-25 Daiichi Seiyaku Co Compostos dehalogenados

Also Published As

Publication number Publication date
EP1336611A1 (en) 2003-08-20
WO2002040478A1 (fr) 2002-05-23
CN1269817C (zh) 2006-08-16
NO20032255D0 (no) 2003-05-19
JP2005194274A (ja) 2005-07-21
DE60130359D1 (de) 2007-10-18
AR035599A1 (es) 2004-06-16
MY136916A (en) 2008-11-28
TWI315308B (en) 2009-10-01
US20040063754A1 (en) 2004-04-01
CA2429440C (en) 2009-12-29
US20070123560A1 (en) 2007-05-31
ATE372338T1 (de) 2007-09-15
MXPA03004437A (es) 2004-05-04
ES2292642T3 (es) 2008-03-16
NO20032255L (no) 2003-07-21
EP1336611A4 (en) 2004-07-21
IL155976A (en) 2010-12-30
DE60130359T2 (de) 2008-06-26
IL155976A0 (en) 2003-12-23
CN1486315A (zh) 2004-03-31
JP2004269544A (ja) 2004-09-30
US7902226B2 (en) 2011-03-08
PT1336611E (pt) 2007-12-06
AU2405002A (en) 2002-05-27
HK1056729A1 (en) 2004-02-27
JP3711108B2 (ja) 2005-10-26
JP3760172B2 (ja) 2006-03-29
CA2429440A1 (en) 2002-05-23
EP1336611B1 (en) 2007-09-05
NO326157B1 (no) 2008-10-13
KR20030060948A (ko) 2003-07-16
KR100777149B1 (ko) 2007-11-19
JPWO2002040478A1 (ja) 2004-03-25

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA: INT. CL. C07D 471/04, 401/04, 498/04; C07K 5/06, 5/10; A61K 31/4375, 31/4709, 31/5383, 38/05, 38/06, 31/04; A61P 31/00

Ipc: C07D 471/04 (2011.01), C07D 401/04 (2011.01), C07D

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 15A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2386 DE 27-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]