BR9805437A - Derivados de benzocicloalquenos heterocìclicos, processo para fabricação de derivados de benzocicloalquenos heterocìclicos e uso de derivados de benzocicloalquenos heterocìclicos. - Google Patents

Derivados de benzocicloalquenos heterocìclicos, processo para fabricação de derivados de benzocicloalquenos heterocìclicos e uso de derivados de benzocicloalquenos heterocìclicos.

Info

Publication number
BR9805437A
BR9805437A BR9805437-6A BR9805437A BR9805437A BR 9805437 A BR9805437 A BR 9805437A BR 9805437 A BR9805437 A BR 9805437A BR 9805437 A BR9805437 A BR 9805437A
Authority
BR
Brazil
Prior art keywords
derivatives
heterocyclic
benzocycloalken
benzocycloalkenes
manufacturing
Prior art date
Application number
BR9805437-6A
Other languages
English (en)
Inventor
Oswald Zimmer
Wolfgang Strassburger
Claudia Puetz
Werner Englberger
Babette-Yvonne Koegel
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of BR9805437A publication Critical patent/BR9805437A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/08—Naphthothiopyrans; Hydrogenated naphthothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Abstract

"DERIVADOS DE BENZOCICLOALQUENOS HETEROCìCLICOS, PROCESSO PARA FABRICAçãO DE DERIVADOS DE BENZOCICLOALQUENOS HETEROCìCLICOS E USO DE DERIVADOS DE BENZOCICLOALQUENOS HETEROCìCLICOS". A invenção se refere a benzocicloalquenos heterocíclicos substituídos da fórmula geral I ou sais dos mesmos, farmaceuticamente utilizáveis, como também um processo para fabricação dos mesmos e o uso dos mesmos como medicamento.
BR9805437-6A 1997-12-13 1998-12-09 Derivados de benzocicloalquenos heterocìclicos, processo para fabricação de derivados de benzocicloalquenos heterocìclicos e uso de derivados de benzocicloalquenos heterocìclicos. BR9805437A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19755480A DE19755480A1 (de) 1997-12-13 1997-12-13 Substituierte heterocyclische Benzocycloalkene und ihre Verwendung als analgetisch wirksame Substanzen

Publications (1)

Publication Number Publication Date
BR9805437A true BR9805437A (pt) 2000-05-02

Family

ID=7851818

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9805437-6A BR9805437A (pt) 1997-12-13 1998-12-09 Derivados de benzocicloalquenos heterocìclicos, processo para fabricação de derivados de benzocicloalquenos heterocìclicos e uso de derivados de benzocicloalquenos heterocìclicos.

Country Status (29)

Country Link
US (1) US6013809A (pt)
EP (1) EP0922703B1 (pt)
JP (1) JPH11246547A (pt)
KR (1) KR19990062982A (pt)
CN (1) CN100376564C (pt)
AR (1) AR017800A1 (pt)
AT (1) ATE229016T1 (pt)
AU (1) AU747979B2 (pt)
BR (1) BR9805437A (pt)
CA (1) CA2256007C (pt)
CO (1) CO4990950A1 (pt)
CZ (1) CZ294990B6 (pt)
DE (2) DE19755480A1 (pt)
DK (1) DK0922703T3 (pt)
ES (1) ES2189072T3 (pt)
HK (1) HK1020944A1 (pt)
HU (1) HU226014B1 (pt)
IL (1) IL127518A (pt)
MY (1) MY133169A (pt)
NO (1) NO985818L (pt)
NZ (1) NZ332622A (pt)
PE (1) PE133499A1 (pt)
PL (1) PL194934B1 (pt)
PT (1) PT922703E (pt)
RU (1) RU2197484C2 (pt)
SI (1) SI0922703T1 (pt)
SK (1) SK283366B6 (pt)
UY (1) UY25296A1 (pt)
ZA (1) ZA9811346B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6077850A (en) * 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
US6221897B1 (en) * 1998-06-10 2001-04-24 Aventis Pharma Deutschland Gmbh Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
DE19830105C1 (de) * 1998-07-06 2000-02-17 Gruenenthal Gmbh Acridinderivate
JP2000128842A (ja) 1998-08-20 2000-05-09 Takeda Chem Ind Ltd ４級アンモニウム塩誘導体およびその用途
DE10033459A1 (de) * 2000-07-10 2002-01-24 Gruenenthal Gmbh Cyclische substituierte Aminomethylverbindungen und diese Verbindungen enthaltende Arzeimittel
US7289083B1 (en) * 2000-11-30 2007-10-30 Palm, Inc. Multi-sided display for portable computer
PL2297089T3 (pl) 2008-04-28 2013-12-31 Janssen Pharmaceutica Nv Pochodne benzocykloheptanu i benzoksepiny
EP3266457A1 (en) 2011-10-28 2018-01-10 Lumena Pharmaceuticals LLC Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases
CN104844471B (zh) * 2015-04-21 2017-05-03 苏州远智医药科技有限公司 一种作为dor受体拮抗剂的化合物
CN109896991B (zh) * 2017-12-08 2020-11-20 苏州远智医药科技有限公司 一种δ阿片受体拮抗剂及其用途和药物组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3444176A (en) * 1967-04-28 1969-05-13 Mcneilab Inc Certain 4-diloweralkylamino-lower alkyl - 5 - pyridyl (or phenyl)-2,3-dihydro - 1 - benzothiepins and derivatives thereof
US4104280A (en) * 1977-02-04 1978-08-01 Syntex (U.S.A.) Inc. Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives
JPS61130286A (ja) * 1984-11-28 1986-06-18 Suntory Ltd ２，３−ジヒドロ−１−ベンズオキセピン誘導体
JP3042156B2 (ja) * 1992-02-20 2000-05-15 田辺製薬株式会社 ナフタレン誘導体、その製法及びその合成中間体
ATE161530T1 (de) * 1992-09-04 1998-01-15 Takeda Chemical Industries Ltd Kondensierte heterozyklische verbindungen, deren herstellung und verwendung

Also Published As

Publication number Publication date
UY25296A1 (es) 2001-05-31
AU9707398A (en) 1999-07-01
IL127518A (en) 2003-05-29
EP0922703B1 (de) 2002-12-04
DE59806523D1 (de) 2003-01-16
KR19990062982A (ko) 1999-07-26
ATE229016T1 (de) 2002-12-15
HK1020944A1 (en) 2000-05-26
CA2256007C (en) 2009-04-14
DK0922703T3 (da) 2003-03-17
AU747979B2 (en) 2002-05-30
SK283366B6 (sk) 2003-06-03
NO985818D0 (no) 1998-12-11
DE19755480A1 (de) 1999-06-24
MY133169A (en) 2007-10-31
CZ294990B6 (cs) 2005-04-13
HU9802886D0 (en) 1999-02-01
CO4990950A1 (es) 2000-12-26
EP0922703A1 (de) 1999-06-16
PT922703E (pt) 2003-04-30
SK169998A3 (en) 1999-07-12
NO985818L (no) 1999-06-14
NZ332622A (en) 2000-03-27
AR017800A1 (es) 2001-10-24
JPH11246547A (ja) 1999-09-14
PL330257A1 (en) 1999-06-21
ES2189072T3 (es) 2003-07-01
HU226014B1 (en) 2008-02-28
HUP9802886A2 (hu) 2001-04-28
CA2256007A1 (en) 1999-06-13
RU2197484C2 (ru) 2003-01-27
PL194934B1 (pl) 2007-07-31
SI0922703T1 (en) 2003-04-30
IL127518A0 (en) 1999-10-28
CZ407698A3 (cs) 1999-06-16
CN100376564C (zh) 2008-03-26
ZA9811346B (en) 1999-06-14
CN1221743A (zh) 1999-07-07
PE133499A1 (es) 2000-02-02
HUP9802886A3 (en) 2001-09-28
US6013809A (en) 2000-01-11

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1912 DE 28/08/2007.