BR0312550A - Derivados de nocatiacina o-derivatizados - Google Patents

Derivados de nocatiacina o-derivatizados

Info

Publication number
BR0312550A
BR0312550A BR0312550-5A BR0312550A BR0312550A BR 0312550 A BR0312550 A BR 0312550A BR 0312550 A BR0312550 A BR 0312550A BR 0312550 A BR0312550 A BR 0312550A
Authority
BR
Brazil
Prior art keywords
nocatiacin
derivatives
derivatized
mycobacteria
derived
Prior art date
Application number
BR0312550-5A
Other languages
English (en)
Inventor
Thomas W Hudyma
Xiaofan Zheng
B Narasimhulu Naidu
Margaret E Sorenson
Alicia Regueiro-Ren
Timothy P Connolly
John D Matiskella
Oak K Kim
Yunhui Zhang
Dane M Springer
Jason Goodrich
Yasutsugu Ueda
Joanne J Bronson
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of BR0312550A publication Critical patent/BR0312550A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

"DERIVADOS DE NOCATIACINA O-DERIVATIZADOS". A presente invenção refere-se a compostos de fórmula (I) tendo potente atividade antibiótica, incluindo atividade voltada para bactérias gram-positivas e micobactérias.
BR0312550-5A 2002-07-03 2003-07-02 Derivados de nocatiacina o-derivatizados BR0312550A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/189,710 US7022667B2 (en) 2002-07-03 2002-07-03 O-derivatized nocathiacin derivatives
PCT/US2003/021012 WO2004004646A2 (en) 2002-07-03 2003-07-02 O-derivatized nocathiacin derivatives

Publications (1)

Publication Number Publication Date
BR0312550A true BR0312550A (pt) 2005-04-26

Family

ID=30114034

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0312550-5A BR0312550A (pt) 2002-07-03 2003-07-02 Derivados de nocatiacina o-derivatizados

Country Status (9)

Country Link
US (1) US7022667B2 (pt)
EP (1) EP1531854A4 (pt)
JP (1) JP2005536492A (pt)
CN (1) CN1678340A (pt)
AU (1) AU2003247783A1 (pt)
BR (1) BR0312550A (pt)
CA (1) CA2491074A1 (pt)
MX (1) MXPA05000140A (pt)
WO (1) WO2004004646A2 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4036440B2 (ja) * 2002-03-29 2008-01-23 東洋合成工業株式会社 新規な感光性化合物及び感光性樹脂並びに感光性組成物
KR20090036544A (ko) 2006-04-18 2009-04-14 피라말 라이프 사이언시스 리미티드 신규한 항균성 화합물
GB0609617D0 (en) * 2006-05-16 2006-06-21 Astrazeneca Ab Process & intermediate
US20080242597A1 (en) * 2006-10-20 2008-10-02 Kun Liu Antibiotic compounds
US20080132500A1 (en) * 2006-10-20 2008-06-05 Kun Liu Antibiotic compounds
WO2022149618A1 (ja) * 2021-01-06 2022-07-14 中外製薬株式会社 酸性官能基のアルキル化方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002520365A (ja) 1998-07-16 2002-07-09 ブリストルーマイヤーズ スクイブ カンパニー ノカチアシン抗生物質
JP2002524466A (ja) 1998-09-04 2002-08-06 ブリストルーマイヤーズ スクイブ カンパニー 微生物生物変換により生産されるノカチアシン抗生物質誘導体
US6287827B1 (en) * 1999-05-05 2001-09-11 Bristol-Myers Squibb Company Halo- or hydroxy-substituted nocathiacin antibiotics
US20020055465A1 (en) 2000-08-14 2002-05-09 Wenying Li Nocathiacin antibiotics prepared by biotransformation or chemical methods
US20020065219A1 (en) 2000-08-15 2002-05-30 Naidu B. Narasimhulu Water soluble thiazolyl peptide derivatives

Also Published As

Publication number Publication date
WO2004004646A3 (en) 2004-09-16
CN1678340A (zh) 2005-10-05
US20040018963A1 (en) 2004-01-29
US7022667B2 (en) 2006-04-04
MXPA05000140A (es) 2005-04-11
JP2005536492A (ja) 2005-12-02
EP1531854A2 (en) 2005-05-25
CA2491074A1 (en) 2004-01-15
AU2003247783A1 (en) 2004-01-23
WO2004004646A2 (en) 2004-01-15
EP1531854A4 (en) 2006-06-28

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]