BR0308201A - Derivados de quinolina - Google Patents

Derivados de quinolina

Info

Publication number
BR0308201A
BR0308201A BR0308201-6A BR0308201A BR0308201A BR 0308201 A BR0308201 A BR 0308201A BR 0308201 A BR0308201 A BR 0308201A BR 0308201 A BR0308201 A BR 0308201A
Authority
BR
Brazil
Prior art keywords
quinoline derivatives
derivatives
quinoline
pharmaceuticals
preparation
Prior art date
Application number
BR0308201-6A
Other languages
English (en)
Inventor
Peter Gull
Esteban Pombo Villar
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR0308201A publication Critical patent/BR0308201A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

"DERIVADOS DE QUINOLINA". A presente invenção refere-se a novos derivados de benzo[g]quinolina, à sua preparação, a seu uso como produtos farmacêuticos e a composições farmacêuticas que contêm esses derivados.
BR0308201-6A 2002-03-07 2003-03-06 Derivados de quinolina BR0308201A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02005115 2002-03-07
EP02005117 2002-03-07
PCT/EP2003/002321 WO2003074511A1 (en) 2002-03-07 2003-03-06 Quinoline derivatives

Publications (1)

Publication Number Publication Date
BR0308201A true BR0308201A (pt) 2005-01-04

Family

ID=27790094

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0308201-6A BR0308201A (pt) 2002-03-07 2003-03-06 Derivados de quinolina

Country Status (29)

Country Link
US (2) US7399768B2 (pt)
EP (1) EP1480970B1 (pt)
JP (2) JP2005519117A (pt)
KR (1) KR101027977B1 (pt)
CN (2) CN1293070C (pt)
AR (1) AR038730A1 (pt)
AU (1) AU2003219023B2 (pt)
BR (1) BR0308201A (pt)
CA (2) CA2706618A1 (pt)
CO (1) CO5611196A2 (pt)
CY (1) CY1106409T1 (pt)
DE (1) DE60311233T2 (pt)
DK (1) DK1480970T3 (pt)
EC (1) ECSP045271A (pt)
EG (1) EG24415A (pt)
ES (1) ES2279100T3 (pt)
HK (1) HK1071364A1 (pt)
IL (1) IL163769A0 (pt)
MX (1) MXPA04008666A (pt)
MY (1) MY134325A (pt)
NO (1) NO20044117L (pt)
NZ (1) NZ534732A (pt)
PE (1) PE20030927A1 (pt)
PL (2) PL215012B1 (pt)
PT (1) PT1480970E (pt)
RU (1) RU2345991C2 (pt)
SI (1) SI1480970T1 (pt)
TW (1) TW200406401A (pt)
WO (1) WO2003074511A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1757601B1 (en) * 2002-03-07 2009-08-05 Novartis AG Quinoline derivatives and their use in glaucoma and myopia
MA50800A (fr) 2017-11-24 2020-09-30 H Lundbeck As Nouveaux promédicaments de catécholamine destinés à être utilisés dans le traitement de la maladie de parkinson
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL100555A (en) * 1991-02-07 2000-08-31 Hoechst Marion Roussel Inc N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them
GB9326010D0 (en) * 1993-12-21 1994-02-23 Sandoz Ltd Improvements in or relating to organic compounds
TW378209B (en) * 1996-07-08 2000-01-01 Novartis Ag Benzo[g]quinoline derivatives, their preparation and the pharmaceutical composition containing them
PE20030240A1 (es) * 2001-07-09 2003-04-16 Novartis Ag DERIVADOS DE BENZO [g] QUINOLINA

Also Published As

Publication number Publication date
DK1480970T3 (da) 2007-03-05
TW200406401A (en) 2004-05-01
IL163769A0 (en) 2005-12-18
MXPA04008666A (es) 2004-12-06
HK1071364A1 (en) 2005-07-15
SI1480970T1 (sl) 2007-06-30
CY1106409T1 (el) 2011-10-12
PL370915A1 (en) 2005-06-13
AR038730A1 (es) 2005-01-26
PE20030927A1 (es) 2003-12-26
JP2005519117A (ja) 2005-06-30
PT1480970E (pt) 2007-03-30
ECSP045271A (es) 2004-10-26
CA2706618A1 (en) 2003-09-12
KR20040089615A (ko) 2004-10-21
RU2004129767A (ru) 2005-06-27
CA2477720A1 (en) 2003-09-12
CN1293070C (zh) 2007-01-03
PL215012B1 (pl) 2013-10-31
EG24415A (en) 2009-05-25
PL394208A1 (pl) 2011-08-16
DE60311233T2 (de) 2007-11-15
EP1480970B1 (en) 2007-01-17
RU2345991C2 (ru) 2009-02-10
AU2003219023A1 (en) 2003-09-16
US20050234085A1 (en) 2005-10-20
US7399768B2 (en) 2008-07-15
US20080255176A1 (en) 2008-10-16
CO5611196A2 (es) 2006-02-28
EP1480970A1 (en) 2004-12-01
AU2003219023B2 (en) 2006-11-30
KR101027977B1 (ko) 2011-04-13
CA2477720C (en) 2010-09-21
CN1639148A (zh) 2005-07-13
MY134325A (en) 2007-12-31
NZ534732A (en) 2006-05-26
NO20044117L (no) 2004-09-28
CN1939915A (zh) 2007-04-04
ES2279100T3 (es) 2007-08-16
DE60311233D1 (de) 2007-03-08
JP2010095550A (ja) 2010-04-30
WO2003074511A1 (en) 2003-09-12
PL210336B1 (pl) 2012-01-31

Similar Documents

Publication Publication Date Title
BRPI0408347A (pt) derivados de pirimidina
AR066982A2 (es) Compuestos heteroaromaticos sustituidos como inhibidoress tirosin quinasa, composiciones farmaceuticas que los contiene y su uso en la preparacion de medicamentos
SE0001899D0 (sv) New compounds
TR200101961T2 (tr) 1,2-halkalı kinolin türevleri
BR0214666A (pt) Derivados de acetileno tendo atividade antagonìstica de mglur5
BR0010215A (pt) Derivados de indolina como antagonistas de progesterona
PT1109812E (pt) Pirrolobenzodiazepinas
BR0111667A (pt) Novos compostos
BR0112030A (pt) Novos compostos que possuem atividade antibacteriana, antifúngica ou antitumor
BR9713363A (pt) Epotilonas c, d, e e f, preparação e composições
BR0107888A (pt) Pirrolidinas 1,3-dissubstituidas como antagonistas de alfa-2adrenorreceptor
BRPI0512677A2 (pt) derivados de quinazolina
BR0210028A (pt) Agentes antibacterianos
BR0310077A (pt) Novos compostos e sua utilização
BR0209440A (pt) Sulfonamidas
BRPI0509067A (pt) formulações de matriz oral que compreendem licarbazepina
BRPI0418255A (pt) derivados de piperazina e piperidina n-substituìdos
BR0314195A (pt) Derivados de piridina substituìda como agentes antitumorais
BR0212353A (pt) Composto, composição farmacêutica, e, uso de um composto
HN2001000235A (es) Derivados puentes de piperazina
BRPI0417950A (pt) composições farmacêuticas
BR0208566A (pt) Derivados de beta-carbolina
BR0308201A (pt) Derivados de quinolina
HN1998000045A (es) Composiciones farmaceuticas
BR9705456A (pt) Compostos heterocìclicos, processo de aminometila para sua preparação e composições farmacêuticas que os contêm.

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8, 10, 13 E 25 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.