BR0209440A - Sulfonamidas - Google Patents

Sulfonamidas

Info

Publication number
BR0209440A
BR0209440A BR0209440-1A BR0209440A BR0209440A BR 0209440 A BR0209440 A BR 0209440A BR 0209440 A BR0209440 A BR 0209440A BR 0209440 A BR0209440 A BR 0209440A
Authority
BR
Brazil
Prior art keywords
sulfonamides
sulphonamids
urotensin
antagonists
pharmaceutical compositions
Prior art date
Application number
BR0209440-1A
Other languages
English (en)
Inventor
Dashyant Dhanak
Timothy F Gallagher
Steven D Knight
Original Assignee
Smithkline Beecham Corporatiio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corporatiio filed Critical Smithkline Beecham Corporatiio
Publication of BR0209440A publication Critical patent/BR0209440A/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Addiction (AREA)
  • Anesthesiology (AREA)
  • Ophthalmology & Optometry (AREA)

Abstract

"SULFONAMIDAS". A presente invenção está relacionada com as sulfonamidas, suas composições farmacêuticas e seus usos como antagonistas da urotensina II.
BR0209440-1A 2001-05-07 2002-05-07 Sulfonamidas BR0209440A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28932701P 2001-05-07 2001-05-07
PCT/US2002/014543 WO2002089792A1 (en) 2001-05-07 2002-05-07 Sulfonamides

Publications (1)

Publication Number Publication Date
BR0209440A true BR0209440A (pt) 2004-08-03

Family

ID=23111049

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209440-1A BR0209440A (pt) 2001-05-07 2002-05-07 Sulfonamidas

Country Status (21)

Country Link
US (2) US7091204B2 (pt)
EP (2) EP1385840B1 (pt)
JP (2) JP2004529939A (pt)
KR (1) KR20030094384A (pt)
CN (1) CN1516580A (pt)
AR (1) AR033879A1 (pt)
AT (1) ATE341544T1 (pt)
BR (1) BR0209440A (pt)
CA (1) CA2446365A1 (pt)
CO (1) CO5540284A2 (pt)
CZ (1) CZ20033018A3 (pt)
DE (1) DE60215145T2 (pt)
ES (1) ES2272705T3 (pt)
HU (1) HUP0400040A2 (pt)
IL (1) IL158626A0 (pt)
MX (1) MXPA03010158A (pt)
NO (1) NO20034949D0 (pt)
NZ (1) NZ528997A (pt)
PL (1) PL366641A1 (pt)
WO (2) WO2002090348A1 (pt)
ZA (1) ZA200308133B (pt)

Families Citing this family (20)

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Publication number Priority date Publication date Assignee Title
AU2003291303A1 (en) * 2002-11-06 2004-06-03 Smithkline Beecham Corporation Sulfonamides
US7288538B2 (en) 2003-02-20 2007-10-30 Encysive Pharmaceuticals, Inc. Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists
AU2004212985B2 (en) * 2003-02-20 2010-10-14 Encysive Pharmaceuticals Inc. Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists
US7320989B2 (en) 2003-02-28 2008-01-22 Encysive Pharmaceuticals, Inc. Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists
EP1603884A4 (en) 2003-02-28 2008-05-28 Encysive Pharmaceuticals Inc PYRIDINE, PYRIMIDINE, QUINOLINE, QUINAZOLINE AND NAPHTHALENE UROTENSIN II RECEPTOR ANTAGONISTS
WO2004087700A1 (fr) 2003-03-25 2004-10-14 Laboratoires Fournier S.A. Derives du benzenesulfonamide, leur procede de preparation et leur utilisation de la douleur
FR2852958B1 (fr) * 2003-03-25 2005-06-24 Fournier Lab Sa Nouveaux derives de benzenesulfonamides et leur utilisation en therapeutique
JP4851328B2 (ja) 2003-09-26 2012-01-11 アクテリオン ファーマシューティカルズ リミテッド 新規なピリジン誘導体
WO2005034873A2 (en) * 2003-10-09 2005-04-21 Smithkline Beecham Corporation A method for reducing anti-neoplastic agent induced side-effects
AR051213A1 (es) 2004-10-12 2006-12-27 Actelion Pharmaceuticals Ltd 1-(2-(4-bencil-4-hidroxi-piperidin-1-il)-etil)-3-(2-metil-quinolin-4-il)-urea como una sal sulfato cristalina
CL2007002097A1 (es) * 2006-07-20 2008-01-18 Smithkline Beecham Corp Compuestos derivados de pirrolidina o morfolina antagonistas de urotensina ii; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar insuficiencia cardiaca congestiva, insuficiencia cardiaca isquemica, angina, isquemia del miocardio, vejiga hiperactiva, asma y/o copd, entre otras.
FR2904827B1 (fr) * 2006-08-11 2008-09-19 Sanofi Aventis Sa Derives de 5,6-bisaryl-2-pyridine-carboxamide, leur preparation et leur application en therapeutique comme antiganistes des recepteurs a l'urotensine ii
US8141182B2 (en) * 2007-03-17 2012-03-27 Cook Joseph R Method of manufacturing and installation of prefabricated shower bench and associated shower bench
CN101525307A (zh) * 2009-04-17 2009-09-09 大连凯飞精细化工有限公司 对磺酰氯苯丙酸甲酯的合成方法
US9068166B2 (en) 2010-09-16 2015-06-30 Industry-Academic Cooperation Foundation Yonsei University Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes
DE102011104267A1 (de) 2011-06-06 2012-12-06 Philipps-Universität Marburg Verbindungen als PPAR beta/delta Inhibitoren für die Behandlung von PPAR beta/delta-vermittelten Erkrankungen
DE102011118606A1 (de) 2011-11-15 2013-05-16 Philipps-Universität Marburg Stilben-Verbindungen als PPAR beta/delta Inhibitoren für die Behandlung von PPAR beta/delta-vermittelten Erkrankungen
JP6957598B2 (ja) * 2017-03-08 2021-11-02 武田薬品工業株式会社 置換ピロリジン化合物およびその用途
KR102278691B1 (ko) * 2019-08-09 2021-07-16 한국화학연구원 신규한 피리미딘 설폰아마이드 유도체
US11773603B2 (en) 2021-09-23 2023-10-03 Tile Redi, Llc Reinforced floors for modular bathrooms

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3637974B2 (ja) 1993-03-25 2005-04-13 エーザイ株式会社 ピロリジン誘導体
DZ2376A1 (fr) * 1996-12-19 2002-12-28 Smithkline Beecham Plc Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant.
ES2317688T3 (es) * 1998-01-29 2009-04-16 Amgen Inc. Moduladores ppar-gamma.
EP1399137A4 (en) * 2001-05-07 2005-12-14 Smithkline Beecham Corp SULPHONAMIDES

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JP2004529939A (ja) 2004-09-30
DE60215145T2 (de) 2007-08-23
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EP1385507A1 (en) 2004-02-04
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CA2446365A1 (en) 2002-11-14
US20040152906A1 (en) 2004-08-05
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AR033879A1 (es) 2004-01-07
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PL366641A1 (en) 2005-02-07
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WO2002090348A1 (en) 2002-11-14
ATE341544T1 (de) 2006-10-15
JP2004529169A (ja) 2004-09-24
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US20040152891A1 (en) 2004-08-05
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