CL2007002097A1 - Compuestos derivados de pirrolidina o morfolina antagonistas de urotensina ii; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar insuficiencia cardiaca congestiva, insuficiencia cardiaca isquemica, angina, isquemia del miocardio, vejiga hiperactiva, asma y/o copd, entre otras. - Google Patents

Compuestos derivados de pirrolidina o morfolina antagonistas de urotensina ii; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar insuficiencia cardiaca congestiva, insuficiencia cardiaca isquemica, angina, isquemia del miocardio, vejiga hiperactiva, asma y/o copd, entre otras.

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Publication number
CL2007002097A1
CL2007002097A1 CL2007002097A CL2007002097A CL2007002097A1 CL 2007002097 A1 CL2007002097 A1 CL 2007002097A1 CL 2007002097 A CL2007002097 A CL 2007002097A CL 2007002097 A CL2007002097 A CL 2007002097A CL 2007002097 A1 CL2007002097 A1 CL 2007002097A1
Authority
CL
Chile
Prior art keywords
heart failure
compounds
angina
pyrrolidine
morpholine
Prior art date
Application number
CL2007002097A
Other languages
English (en)
Inventor
Krista B Goodman
Michael J Neeb
Clark A Sehon
Andrew Q Viet
Gren Z Wang
Original Assignee
Smithkline Beecham Corp
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38957113&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2007002097(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of CL2007002097A1 publication Critical patent/CL2007002097A1/es

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36—One oxygen atom
    • C07D263/38—One oxygen atom attached in position 2
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    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
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Abstract

Compuestos derivados de pirrolidina, morfolina o benzoxazina; composición farmacéutica que comprende a dichos compuestos; y su uso para tratar insuficiencia cardiaca congestiva, apoplejía, insuficiencia cardiaca isquémica, angina, isquemia del miocardio, vejiga hiperactiva o arritmia cardiaca.
CL2007002097A 2006-07-20 2007-07-16 Compuestos derivados de pirrolidina o morfolina antagonistas de urotensina ii; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar insuficiencia cardiaca congestiva, insuficiencia cardiaca isquemica, angina, isquemia del miocardio, vejiga hiperactiva, asma y/o copd, entre otras. CL2007002097A1 (es)

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KR20090031635A (ko) 2009-03-26
US20090275571A1 (en) 2009-11-05
US7749998B2 (en) 2010-07-06
US7432258B2 (en) 2008-10-07
CN101516378A (zh) 2009-08-26
TW200819132A (en) 2008-05-01
CN101516378B (zh) 2011-06-15
CA2660320A1 (en) 2008-01-24
PE20080429A1 (es) 2008-06-05
US20100256130A1 (en) 2010-10-07
WO2008011551A1 (en) 2008-01-24
EA017528B1 (ru) 2013-01-30
EA200970132A1 (ru) 2009-08-28
JP2009544623A (ja) 2009-12-17
EP2049118A4 (en) 2011-09-14
US20080021023A1 (en) 2008-01-24
EP2049118A1 (en) 2009-04-22
AU2007275212A1 (en) 2008-01-24
AU2007275212B2 (en) 2012-07-05

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