EA200970132A1 - Аналоги морфолинила и пирролидинила - Google Patents

Аналоги морфолинила и пирролидинила

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Publication number
EA200970132A1
EA200970132A1 EA200970132A EA200970132A EA200970132A1 EA 200970132 A1 EA200970132 A1 EA 200970132A1 EA 200970132 A EA200970132 A EA 200970132A EA 200970132 A EA200970132 A EA 200970132A EA 200970132 A1 EA200970132 A1 EA 200970132A1
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EA
Eurasian Patent Office
Prior art keywords
pyrrolidinyl
morphinol
analogues
urotensin
morpholinyl
Prior art date
Application number
EA200970132A
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English (en)
Other versions
EA017528B1 (ru
Inventor
Майкл Дж. Ниб
Кларк А. Сехон
Эндрю К. Вит
Криста Б. Гудман
Грен З. Ван
Original Assignee
Смитклайн Бичам Корпорейшн
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Publication date
Family has litigation
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Application filed by Смитклайн Бичам Корпорейшн filed Critical Смитклайн Бичам Корпорейшн
Publication of EA200970132A1 publication Critical patent/EA200970132A1/ru
Publication of EA017528B1 publication Critical patent/EA017528B1/ru

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    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
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    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36—One oxygen atom
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Abstract

Настоящее изобретение относится к морфолинилу и аналогам пирролидинила, содержащим их фармацевтическим композициям и их применению в качестве антагонистов уротензина II.
EA200970132A 2006-07-20 2007-07-20 Аналоги морфолинила и пирролидинила EA017528B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83217606P 2006-07-20 2006-07-20
US87020206P 2006-12-15 2006-12-15
PCT/US2007/073951 WO2008011551A1 (en) 2006-07-20 2007-07-20 Morpholinyl and pyrrolidinyl analogs

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EP2049118A1 (en) 2009-04-22
KR20090031635A (ko) 2009-03-26
US20090275571A1 (en) 2009-11-05
EA017528B1 (ru) 2013-01-30
PE20080429A1 (es) 2008-06-05
US20100256130A1 (en) 2010-10-07
CN101516378B (zh) 2011-06-15
CL2007002097A1 (es) 2008-01-18
JP2009544623A (ja) 2009-12-17
US20080021023A1 (en) 2008-01-24
CA2660320A1 (en) 2008-01-24
AU2007275212B2 (en) 2012-07-05
EP2049118A4 (en) 2011-09-14
WO2008011551A1 (en) 2008-01-24
AR061917A1 (es) 2008-10-01
US7432258B2 (en) 2008-10-07
TW200819132A (en) 2008-05-01
US7749998B2 (en) 2010-07-06
CN101516378A (zh) 2009-08-26
AU2007275212A1 (en) 2008-01-24

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