MA50800A - Nouveaux promédicaments de catécholamine destinés à être utilisés dans le traitement de la maladie de parkinson - Google Patents
Nouveaux promédicaments de catécholamine destinés à être utilisés dans le traitement de la maladie de parkinsonInfo
- Publication number
- MA50800A MA50800A MA050800A MA50800A MA50800A MA 50800 A MA50800 A MA 50800A MA 050800 A MA050800 A MA 050800A MA 50800 A MA50800 A MA 50800A MA 50800 A MA50800 A MA 50800A
- Authority
- MA
- Morocco
- Prior art keywords
- catecholamine
- parkinson
- disease
- treatment
- new
- Prior art date
Links
- 208000018737 Parkinson disease Diseases 0.000 title 1
- 150000003943 catecholamines Chemical class 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA201700674 | 2017-11-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA50800A true MA50800A (fr) | 2020-09-30 |
Family
ID=64661284
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA050800A MA50800A (fr) | 2017-11-24 | 2018-11-23 | Nouveaux promédicaments de catécholamine destinés à être utilisés dans le traitement de la maladie de parkinson |
Country Status (25)
Country | Link |
---|---|
US (3) | US10729710B2 (fr) |
EP (1) | EP3713933A1 (fr) |
JP (4) | JP7320507B2 (fr) |
KR (1) | KR20200092955A (fr) |
CN (3) | CN117653649A (fr) |
AR (1) | AR113908A1 (fr) |
AU (2) | AU2018371193B2 (fr) |
BR (1) | BR112019014981A2 (fr) |
CA (1) | CA3082757A1 (fr) |
CL (1) | CL2020001343A1 (fr) |
CO (1) | CO2020006224A2 (fr) |
CR (1) | CR20200225A (fr) |
EA (1) | EA202090987A8 (fr) |
EC (1) | ECSP20030074A (fr) |
GE (1) | GEP20227446B (fr) |
IL (1) | IL274648A (fr) |
JO (1) | JOP20200114A1 (fr) |
MA (1) | MA50800A (fr) |
MX (2) | MX2020005366A (fr) |
PE (1) | PE20211290A1 (fr) |
PH (1) | PH12020550631A1 (fr) |
SG (1) | SG11202004461YA (fr) |
TW (1) | TWI816716B (fr) |
UA (1) | UA127575C2 (fr) |
WO (1) | WO2019101917A1 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA50800A (fr) * | 2017-11-24 | 2020-09-30 | H Lundbeck As | Nouveaux promédicaments de catécholamine destinés à être utilisés dans le traitement de la maladie de parkinson |
US11111263B2 (en) | 2019-05-20 | 2021-09-07 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
US11168056B2 (en) | 2019-05-20 | 2021-11-09 | H. Lundbeck A/S | Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol |
US11130775B2 (en) * | 2019-05-20 | 2021-09-28 | H. Lundbeck A/S | Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
US11104697B2 (en) | 2019-05-20 | 2021-08-31 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
JP2022533311A (ja) | 2019-05-21 | 2022-07-22 | ハー・ルンドベック・アクチエゼルスカベット | パーキンソン病の治療に使用するための新規なカテコールアミンプロドラッグ |
US20220220077A1 (en) * | 2019-05-21 | 2022-07-14 | H. Lundbeck A/S | New catecholamine prodrugs for use in the treatment of parkinson's disease |
CN113727979A (zh) * | 2019-05-21 | 2021-11-30 | H.隆德贝克有限公司 | 用于治疗帕金森病的新儿茶酚胺前药 |
JP2023552699A (ja) | 2020-11-17 | 2023-12-19 | ハー・ルンドベック・アクチエゼルスカベット | パーキンソン病の治療に使用するための新規なカテコールアミンプロドラッグ |
WO2023208865A1 (fr) | 2022-04-25 | 2023-11-02 | Integrative Research Laboratories Sweden Ab | Nouveaux composés de 1,2,3,4,4a,5,6,7,8,9,10,10a-dodécahydrobenzo[g]quinolin-6-ol et leurs utilisations |
WO2023208867A1 (fr) | 2022-04-25 | 2023-11-02 | Integrative Research Laboratories Sweden Ab | Nouveaux composés de 1,2,3,4,4a,5,8,9,10,10a-décahydrobenzo[g]quinolin-6(7h)-one et leurs utilisations |
WO2023208869A1 (fr) | 2022-04-25 | 2023-11-02 | Integrative Research Laboratories Sweden Ab | Nouveaux esters de composés 1,2,3,4,4a,5,6,7,8,9,10,10a-dodécahydrobenzo[g]quinolin-6-ol et leurs utilisations |
WO2023242355A1 (fr) | 2022-06-15 | 2023-12-21 | Ever Neuro Pharma Gmbh | Promédicaments d'apomorphine et leurs utilisations |
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US3132171A (en) | 1962-06-18 | 1964-05-05 | Strong Cobb Arner Inc | 3, 4-diphosphatophenyl-alanine and process for making same |
US4543256A (en) | 1982-03-17 | 1985-09-24 | Northeastern University | (-)-10,1L Methylenedioxy-N-N-propylnoraporphine and methods employing it for inhibiting the effects of epileptic seizures and for prevention and treatment of duodenal ulcers |
EP0077754B1 (fr) | 1981-10-16 | 1990-09-26 | Sandoz Ag | Dérivés de 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline avec activité pharmaceutique |
PH22782A (en) | 1983-02-01 | 1988-12-12 | Sandoz Ltd | Novel pharmaceutical active 1,2,3,4,4a,5,10,10a octahydrobenzo(g)quinoline derivatives |
JPS60172975A (ja) | 1984-02-15 | 1985-09-06 | Sumitomo Chem Co Ltd | エリスロ−3−(3,4−メチレンジオキシフエニル)セリンの製造方法 |
GB2192394A (en) | 1986-07-11 | 1988-01-13 | Glaxo Group Ltd | Amine derivatives |
IT1226727B (it) | 1988-07-29 | 1991-02-05 | Simes | Farmaci precursori della dopamina. |
EP0393781B1 (fr) | 1989-04-20 | 1995-02-08 | ZAMBON GROUP S.p.A. | Dopamine, précurseur de médicament |
WO1990012574A1 (fr) | 1989-04-25 | 1990-11-01 | Northeastern University | Composes agonistes de la dopamine |
IT1271411B (it) | 1993-09-14 | 1997-05-28 | Zambon Spa | Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare |
US5955468A (en) | 1993-12-21 | 1999-09-21 | Sandoz Ltd. | Benzo G!quinolines for use in prevention or delay of progressive atrophy of the optic nerve |
TW357143B (en) | 1995-07-07 | 1999-05-01 | Novartis Ag | Benzo[g]quinoline derivatives |
IT1289979B1 (it) | 1997-02-26 | 1998-10-19 | Zambon Spa | 5-idrossimetil-6-idrossi-2-amminotetraline attive come agenti cardiovascolari |
GB9902938D0 (en) | 1999-02-10 | 1999-03-31 | Novartis Ag | Organic compounds |
CO5261532A1 (es) | 1999-11-15 | 2003-03-31 | Novartis Ag | Compuestos heterociclicos sililados, procedimiento para la preparacion de estos y composicion farmaceutica que los contiene |
US6506765B2 (en) | 2000-04-07 | 2003-01-14 | Tap Pharmaceutical Products, Inc. | Apomorphine derivatives and methods for their use |
SE0001438D0 (sv) | 2000-04-18 | 2000-04-18 | Axon Chemicals Bv | New chemical compounds and their use in therapy |
MXPA03001272A (es) | 2000-08-11 | 2004-04-02 | Purdue Research Foundation | Procedimiento para la preparacion de dinapsolina. |
SE0102036D0 (sv) | 2001-06-08 | 2001-06-08 | Axon Biochemicals Bv | Pharmaceutical formulation for the efficient administration of apomorphine, 6aR- (-) -N- Propyl- norapomorphine and their derivatives and pro-drugs thereof |
PE20030240A1 (es) | 2001-07-09 | 2003-04-16 | Novartis Ag | DERIVADOS DE BENZO [g] QUINOLINA |
JP2005504758A (ja) | 2001-08-10 | 2005-02-17 | パーデュー・リサーチ・ファウンデーション | キラル・ジナプソリン |
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WO2003080074A1 (fr) | 2002-03-19 | 2003-10-02 | Michael Holick | Derives de glycoside et de glycoside orthoester d'apomorphine, d'analogues et utilisations correspondantes |
US7101912B2 (en) | 2002-12-06 | 2006-09-05 | Xenoport, Inc. | Carbidopa prodrugs and derivatives, and compositions and uses thereof |
AU2004308413A1 (en) | 2003-12-23 | 2005-07-14 | Darpharma, Inc. | Co-administration of dopamine-receptor binding compounds |
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US8129530B2 (en) | 2007-08-31 | 2012-03-06 | H. Lundbeck A/S | Catecholamine derivatives and prodrugs thereof |
TWI404702B (zh) | 2007-08-31 | 2013-08-11 | Lundbeck & Co As H | 兒茶酚胺衍生物和其前藥 |
TW201035054A (en) | 2009-02-27 | 2010-10-01 | Lundbeck & Co As H | Methods of administering (4aR, 10aR)-1-n-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]quinoline-6,7-diol and pharmaceutical compositions thereof |
TW201036949A (en) * | 2009-02-27 | 2010-10-16 | Lundbeck & Co As H | Treatment of dyskinesia related disorders |
EP2557079A1 (fr) | 2011-08-09 | 2013-02-13 | Nestec S.A. | Synthèse de catéchine et conjugués d'épicatéchine |
DE102011112496A1 (de) | 2011-09-07 | 2013-03-07 | Thanares GmbH | 4-Methylcatecholderivate und deren Verwendung |
CN102746351B (zh) | 2012-07-23 | 2018-03-02 | 上海弈柯莱生物医药科技有限公司 | 灯盏花乙素及其类似物的制备方法 |
GB201319768D0 (en) | 2013-11-08 | 2013-12-25 | Glycosynth Ltd | Naphthalene derived chromogenic enzyme substrates |
SI3209302T1 (sl) | 2014-10-21 | 2019-06-28 | Abb Vie Inc. | Predzdravila karbidope in L-dope in njihova uporaba za zdravljenje parkinsonove bolezni |
CN105218606B (zh) | 2015-10-19 | 2017-12-01 | 昆明理工大学 | 一种制备灯盏乙素的方法 |
WO2017184871A1 (fr) | 2016-04-20 | 2017-10-26 | Abbvie Inc. | Promédicaments de carbidopa et de l-dopa et méthodes d'utilisation |
US9920342B2 (en) | 2016-05-17 | 2018-03-20 | Divi's Laboratories Limited | Process for the preparation of Droxidopa |
MA50800A (fr) | 2017-11-24 | 2020-09-30 | H Lundbeck As | Nouveaux promédicaments de catécholamine destinés à être utilisés dans le traitement de la maladie de parkinson |
US11168056B2 (en) | 2019-05-20 | 2021-11-09 | H. Lundbeck A/S | Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol |
US11111263B2 (en) | 2019-05-20 | 2021-09-07 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
US11130775B2 (en) | 2019-05-20 | 2021-09-28 | H. Lundbeck A/S | Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
US11104697B2 (en) | 2019-05-20 | 2021-08-31 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
CN113727979A (zh) | 2019-05-21 | 2021-11-30 | H.隆德贝克有限公司 | 用于治疗帕金森病的新儿茶酚胺前药 |
CN113727712A (zh) | 2019-05-21 | 2021-11-30 | H.隆德贝克有限公司 | 用于治疗帕金森病的儿茶酚胺氨基甲酸酯前药 |
US20220220077A1 (en) | 2019-05-21 | 2022-07-14 | H. Lundbeck A/S | New catecholamine prodrugs for use in the treatment of parkinson's disease |
JP2022533311A (ja) | 2019-05-21 | 2022-07-22 | ハー・ルンドベック・アクチエゼルスカベット | パーキンソン病の治療に使用するための新規なカテコールアミンプロドラッグ |
JP2023013012A (ja) * | 2021-07-15 | 2023-01-26 | 株式会社日立製作所 | 運行提案システム、及び運行提案作成方法 |
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2018
- 2018-11-23 MA MA050800A patent/MA50800A/fr unknown
- 2018-11-23 AR ARP180103436A patent/AR113908A1/es unknown
- 2018-11-23 AU AU2018371193A patent/AU2018371193B2/en active Active
- 2018-11-23 JO JOP/2020/0114A patent/JOP20200114A1/ar unknown
- 2018-11-23 JP JP2020528199A patent/JP7320507B2/ja active Active
- 2018-11-23 CR CR20200225A patent/CR20200225A/es unknown
- 2018-11-23 EA EA202090987A patent/EA202090987A8/ru unknown
- 2018-11-23 KR KR1020207014479A patent/KR20200092955A/ko not_active Application Discontinuation
- 2018-11-23 CN CN202311564635.XA patent/CN117653649A/zh active Pending
- 2018-11-23 EP EP18815537.8A patent/EP3713933A1/fr active Pending
- 2018-11-23 US US16/198,917 patent/US10729710B2/en active Active
- 2018-11-23 SG SG11202004461YA patent/SG11202004461YA/en unknown
- 2018-11-23 GE GEAP201815342A patent/GEP20227446B/en unknown
- 2018-11-23 UA UAA202003060A patent/UA127575C2/uk unknown
- 2018-11-23 CN CN201880075320.XA patent/CN111386267B/zh active Active
- 2018-11-23 MX MX2020005366A patent/MX2020005366A/es unknown
- 2018-11-23 CA CA3082757A patent/CA3082757A1/fr active Pending
- 2018-11-23 BR BR112019014981A patent/BR112019014981A2/pt unknown
- 2018-11-23 WO PCT/EP2018/082361 patent/WO2019101917A1/fr active Application Filing
- 2018-11-23 PE PE2020000566A patent/PE20211290A1/es unknown
- 2018-11-23 CN CN202311564502.2A patent/CN117599073A/zh active Pending
- 2018-11-23 TW TW107141799A patent/TWI816716B/zh active
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2020
- 2020-05-12 US US16/872,802 patent/US11110110B2/en active Active
- 2020-05-13 IL IL274648A patent/IL274648A/en unknown
- 2020-05-14 PH PH12020550631A patent/PH12020550631A1/en unknown
- 2020-05-20 CL CL2020001343A patent/CL2020001343A1/es unknown
- 2020-05-21 CO CONC2020/0006224A patent/CO2020006224A2/es unknown
- 2020-06-03 EC ECSENADI202030074A patent/ECSP20030074A/es unknown
- 2020-07-13 MX MX2022016276A patent/MX2022016276A/es unknown
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2021
- 2021-07-28 US US17/386,686 patent/US11707476B2/en active Active
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2023
- 2023-01-31 JP JP2023013012A patent/JP7320684B2/ja active Active
- 2023-03-21 AU AU2023201741A patent/AU2023201741A1/en not_active Abandoned
- 2023-07-24 JP JP2023119693A patent/JP7443606B2/ja active Active
- 2023-07-24 JP JP2023119694A patent/JP2023145580A/ja active Pending
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