BG106562A - Трициклени инхибитори на поли (adp-рибоза) полимерази - Google Patents

Трициклени инхибитори на поли (adp-рибоза) полимерази Download PDF

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Publication number
BG106562A
BG106562A BG106562A BG10656202A BG106562A BG 106562 A BG106562 A BG 106562A BG 106562 A BG106562 A BG 106562A BG 10656202 A BG10656202 A BG 10656202A BG 106562 A BG106562 A BG 106562A
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BG
Bulgaria
Prior art keywords
aryl
cycloalkyl
alkynyl
alkenyl
heterocycloalkyl
Prior art date
Application number
BG106562A
Other languages
Bulgarian (bg)
English (en)
Inventor
Stephen Webber
Donald SKALITZKY
Jayashree Tikhe
Arnold KUMPF
Joseph MARAKOVITS
Walter EASTMAN
Original Assignee
Agouron Pharmaceuticals, Inc.
Cancer Research Campaign Technology Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agouron Pharmaceuticals, Inc., Cancer Research Campaign Technology Limited filed Critical Agouron Pharmaceuticals, Inc.
Publication of BG106562A publication Critical patent/BG106562A/bg

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BG106562A 1999-08-31 2002-03-29 Трициклени инхибитори на поли (adp-рибоза) полимерази BG106562A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15214299P 1999-08-31 1999-08-31
PCT/US2000/023882 WO2001016136A2 (en) 1999-08-31 2000-08-31 Tricyclic inhibitors of poly(adp-ribose) polymerases

Publications (1)

Publication Number Publication Date
BG106562A true BG106562A (bg) 2003-03-31

Family

ID=22541675

Family Applications (1)

Application Number Title Priority Date Filing Date
BG106562A BG106562A (bg) 1999-08-31 2002-03-29 Трициклени инхибитори на поли (adp-рибоза) полимерази

Country Status (48)

Country Link
US (1) US6548494B1 (de)
EP (1) EP1208104B1 (de)
JP (1) JP4272375B2 (de)
KR (1) KR20020038742A (de)
CN (1) CN1384835A (de)
AP (1) AP1553A (de)
AR (1) AR035162A1 (de)
AT (1) ATE287406T1 (de)
AU (1) AU781826B2 (de)
BG (1) BG106562A (de)
BR (1) BR0015051A (de)
CA (1) CA2382404C (de)
CO (1) CO5200769A1 (de)
CR (1) CR6577A (de)
CZ (1) CZ2002613A3 (de)
DE (1) DE60017575T2 (de)
DK (1) DK1208104T3 (de)
DO (1) DOP2000000069A (de)
DZ (1) DZ3216A1 (de)
EA (1) EA200200306A1 (de)
EC (1) ECSP003637A (de)
EE (1) EE200200100A (de)
ES (1) ES2234657T3 (de)
GE (1) GEP20043268B (de)
GT (1) GT200000145A (de)
HK (1) HK1045509B (de)
HR (1) HRP20020271A2 (de)
HU (1) HUP0202703A3 (de)
IL (1) IL147863A0 (de)
IS (1) IS6289A (de)
MA (1) MA25876A1 (de)
MX (1) MXPA02002138A (de)
MY (1) MY135910A (de)
NO (1) NO322475B1 (de)
NZ (1) NZ516793A (de)
OA (1) OA12016A (de)
PA (1) PA8501801A1 (de)
PE (1) PE20010538A1 (de)
PL (1) PL354242A1 (de)
PT (1) PT1208104E (de)
SI (1) SI1208104T1 (de)
SK (1) SK2592002A3 (de)
SV (1) SV2003000162A (de)
UA (1) UA73144C2 (de)
UY (1) UY26323A1 (de)
WO (1) WO2001016136A2 (de)
YU (1) YU15102A (de)
ZA (1) ZA200200830B (de)

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Publication number Publication date
EP1208104A2 (de) 2002-05-29
MXPA02002138A (es) 2003-08-20
PA8501801A1 (es) 2002-08-26
DK1208104T3 (da) 2005-05-02
ES2234657T3 (es) 2005-07-01
IS6289A (is) 2002-02-27
NO20020421D0 (no) 2002-01-28
CN1384835A (zh) 2002-12-11
NO20020421L (no) 2002-04-25
IL147863A0 (en) 2002-08-14
PL354242A1 (en) 2003-12-29
SK2592002A3 (en) 2002-10-08
HK1045509A1 (en) 2002-11-29
JP2003513015A (ja) 2003-04-08
GT200000145A (es) 2002-02-21
AP1553A (en) 2006-01-18
DOP2000000069A (es) 2002-08-30
AR035162A1 (es) 2004-05-05
JP4272375B2 (ja) 2009-06-03
CA2382404A1 (en) 2001-03-08
US6548494B1 (en) 2003-04-15
WO2001016136A2 (en) 2001-03-08
WO2001016136B1 (en) 2001-11-15
NZ516793A (en) 2004-03-26
AU7338900A (en) 2001-03-26
HUP0202703A2 (hu) 2002-12-28
CR6577A (es) 2003-12-05
HK1045509B (zh) 2005-04-29
UA73144C2 (en) 2005-06-15
DE60017575D1 (de) 2005-02-24
ATE287406T1 (de) 2005-02-15
CA2382404C (en) 2009-03-24
CZ2002613A3 (cs) 2002-08-14
PE20010538A1 (es) 2001-05-22
MA25876A1 (fr) 2003-10-01
WO2001016136A3 (en) 2001-06-21
HUP0202703A3 (en) 2004-12-28
BR0015051A (pt) 2002-06-25
EP1208104B1 (de) 2005-01-19
UY26323A1 (es) 2001-04-30
SI1208104T1 (en) 2005-06-30
MY135910A (en) 2008-07-31
NO322475B1 (no) 2006-10-09
ZA200200830B (en) 2003-03-26
DE60017575T2 (de) 2005-06-09
KR20020038742A (ko) 2002-05-23
EA200200306A1 (ru) 2002-08-29
ECSP003637A (es) 2002-03-25
CO5200769A1 (es) 2002-09-27
OA12016A (en) 2006-04-19
SV2003000162A (es) 2003-07-29
YU15102A (sh) 2004-12-31
PT1208104E (pt) 2005-04-29
GEP20043268B (en) 2004-06-25
AU781826B2 (en) 2005-06-16
HRP20020271A2 (en) 2005-12-31
DZ3216A1 (fr) 2001-03-08
EE200200100A (et) 2003-06-16

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