BG103047A - Гранулат за получаване на бързо разпадащи се и бързо разтварящи се състави с високо съдържание на лекарствено средство - Google Patents

Гранулат за получаване на бързо разпадащи се и бързо разтварящи се състави с високо съдържание на лекарствено средство

Info

Publication number
BG103047A
BG103047A BG103047A BG10304798A BG103047A BG 103047 A BG103047 A BG 103047A BG 103047 A BG103047 A BG 103047A BG 10304798 A BG10304798 A BG 10304798A BG 103047 A BG103047 A BG 103047A
Authority
BG
Bulgaria
Prior art keywords
quick
granulate
preparation
form content
decomposition
Prior art date
Application number
BG103047A
Other languages
English (en)
Other versions
BG64114B1 (bg
Inventor
Bernardus DIJKGRAAF
Aart Muehlenbruch
Original Assignee
Astellas Pharma Europe B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8224133&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG103047(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astellas Pharma Europe B.V. filed Critical Astellas Pharma Europe B.V.
Publication of BG103047A publication Critical patent/BG103047A/bg
Publication of BG64114B1 publication Critical patent/BG64114B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Jellies, Jams, And Syrups (AREA)

Abstract

Гранулатът съдържа активно вещество с разтворимост във вода 1:10 или по-голяма, в смес с до 15% тегл. вододиспергираща се целулоза, включваща микрокристална целулоза и Na-карбоксиметилцелулоза.
BG103047A 1996-07-03 1998-12-30 Гранулат за получаване на бързо разпадащи се и бързо разтварящи се състави с високо съдържание на лекарствено средство BG64114B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96201829 1996-07-03
US08/770,421 US5837292A (en) 1996-07-03 1996-12-20 Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug
PCT/EP1997/003250 WO1998001114A1 (en) 1996-07-03 1997-06-19 Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug

Publications (2)

Publication Number Publication Date
BG103047A true BG103047A (bg) 1999-07-30
BG64114B1 BG64114B1 (bg) 2004-01-30

Family

ID=8224133

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103047A BG64114B1 (bg) 1996-07-03 1998-12-30 Гранулат за получаване на бързо разпадащи се и бързо разтварящи се състави с високо съдържание на лекарствено средство

Country Status (36)

Country Link
US (1) US5837292A (bg)
EP (1) EP0910344B1 (bg)
JP (1) JP4159607B2 (bg)
CN (1) CN1131025C (bg)
AR (1) AR008252A1 (bg)
AT (1) ATE237314T1 (bg)
AU (1) AU731276B2 (bg)
BG (1) BG64114B1 (bg)
BR (1) BR9710181B1 (bg)
CA (1) CA2258841C (bg)
CO (1) CO4890859A1 (bg)
CZ (1) CZ295893B6 (bg)
DE (1) DE69720995T2 (bg)
DK (1) DK0910344T3 (bg)
EA (1) EA001537B1 (bg)
EG (1) EG23814A (bg)
ES (1) ES2197351T3 (bg)
HK (1) HK1021511A1 (bg)
HU (1) HU225115B1 (bg)
ID (1) ID17128A (bg)
IL (1) IL127364A (bg)
JO (1) JO1969B1 (bg)
MY (1) MY116124A (bg)
NO (1) NO320767B1 (bg)
NZ (1) NZ333247A (bg)
PE (1) PE89798A1 (bg)
PL (1) PL188235B1 (bg)
PT (1) PT910344E (bg)
SI (1) SI0910344T1 (bg)
SK (1) SK284175B6 (bg)
TN (1) TNSN97114A1 (bg)
TR (1) TR199802762T2 (bg)
TW (1) TW473392B (bg)
UA (1) UA61917C2 (bg)
WO (1) WO1998001114A1 (bg)
ZA (1) ZA975848B (bg)

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EA004311B1 (ru) * 1998-06-11 2004-02-26 Фармация Энд Апджон Компани Таблетированная фармацевтическая композиция непролонгированного действия
IT1305308B1 (it) * 1999-03-26 2001-05-04 Biosint S P A Granulato ad alto contenuto di l-carnitina o alcanoil-l-carnitina,particolarmente adatto alla produzione di compresse per compressione
EP1180022A4 (en) * 1999-05-14 2004-01-07 Lilly Co Eli PROCESS FOR THE MASS PRODUCTION OF PHARMACEUTICAL MATERIAL WITH UNIFORM SOLUBILITY
HU227070B1 (en) * 1999-08-11 2010-06-28 Egis Gyogyszergyar Nyilvanosan Immediate release pharmaceutical composition containing ciprofloxacin and process for its production
UY26615A1 (es) * 2000-03-16 2001-10-25 Pfizer Prod Inc Inhibidor de la glucogeno fosforilasa.
FR2816507B1 (fr) * 2000-11-16 2003-02-28 Ethypharm Lab Prod Ethiques Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules
US7799342B2 (en) * 2000-12-06 2010-09-21 Wyeth Llc Fast dissolving tablet
US6733781B2 (en) 2000-12-06 2004-05-11 Wyeth Fast dissolving tablet
BR0206979A (pt) * 2001-02-05 2004-04-20 Scherer Technologies Inc R P Métodos e composições para reduzir o paladar de agentes farmaceuticamente ativos
EP1285649A1 (en) * 2001-08-23 2003-02-26 Cimex AG Bilayered dispersible tablet formulation comprising amoxycillin and clavulanate in separate layers
EP1469829B1 (en) * 2002-02-01 2016-01-27 Bend Research, Inc Immediate release dosage forms containing solid drug dispersions
US20030229101A1 (en) * 2002-06-06 2003-12-11 Sherman Bernard Charles Tablets comprising ciprofloxacin hydrochloride
KR20050062514A (ko) * 2002-07-16 2005-06-23 랜박시 래보러터리스 리미티드 경구 투여용 분산성 정제
AU2003247023A1 (en) * 2002-08-02 2004-02-25 Ranbaxy Laboratories Limited A process for the preparation of dispersible tablet of cephalexin
JP4702763B2 (ja) * 2003-07-30 2011-06-15 塩野義製薬株式会社 結晶セルロースを含有する安定な錠剤
US7838029B1 (en) 2003-07-31 2010-11-23 Watson Laboratories, Inc. Mirtazapine solid dosage forms
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
SI3395339T1 (sl) * 2003-09-12 2019-08-30 Amgen, Inc, Hitrotopna formulacija, ki vsebuje cinakalcet HCL
US20050089558A1 (en) * 2003-10-28 2005-04-28 Alamo Pharmaceuticals, Llc Compositions and methods for the co-formulation and administration of tramadol and propoxyphene
EP1681050A1 (en) * 2005-01-13 2006-07-19 Strides Arcolab Limited Dispersible sustained release pharmaceutical compositions
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
EP2043613A1 (en) * 2006-07-14 2009-04-08 Fmc Corporation Solid form
JP5201819B2 (ja) * 2006-11-22 2013-06-05 エスエス製薬株式会社 固形組成物
US20080311162A1 (en) * 2007-05-16 2008-12-18 Olivia Darmuzey Solid form
JP5637624B2 (ja) * 2009-02-12 2014-12-10 富士化学工業株式会社 崩壊性粒子組成物及びそれを用いた速崩壊性圧縮成型物
WO2011152808A1 (en) * 2010-06-03 2011-12-08 Mahmut Bilgic Formulation comprising cefpodoxime proxetil and clavulanic acid
CN101912373B (zh) * 2010-08-24 2012-01-04 北京京丰制药有限公司 稳定的头孢克洛分散片及其制备方法
WO2013151517A1 (en) * 2012-04-04 2013-10-10 Mahmut Bilgic Tablet formulations comprising cefpodoxime proxetil and clavulanic acid
JP2015063521A (ja) * 2013-09-02 2015-04-09 科研製薬株式会社 高い薬物含有率を有する錠剤及びその製造方法
AU2015251692B2 (en) * 2014-04-21 2019-12-19 Daicel Corporation Disintegrating particle composition including microfibrous cellulose
CN110051639B (zh) * 2019-03-15 2021-08-31 河北嘉迈医药科技有限公司 一种快速崩解型尼麦角林片及其制备方法
CN117683469A (zh) * 2023-10-24 2024-03-12 绍兴拓邦新能源股份有限公司 一种晶硅片背面碱抛光固态添加剂及其制备方法

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Also Published As

Publication number Publication date
CA2258841C (en) 2006-05-30
EG23814A (en) 2007-09-12
CN1224348A (zh) 1999-07-28
CO4890859A1 (es) 2000-02-28
EA199900075A1 (ru) 1999-06-24
IL127364A (en) 2003-04-10
UA61917C2 (uk) 2003-12-15
AU3342197A (en) 1998-02-02
SK176798A3 (en) 2000-04-10
ES2197351T3 (es) 2004-01-01
TNSN97114A1 (fr) 2005-03-15
HUP9903308A3 (en) 2001-03-28
AR008252A1 (es) 1999-12-29
JP4159607B2 (ja) 2008-10-01
EP0910344A1 (en) 1999-04-28
NZ333247A (en) 2000-07-28
PE89798A1 (es) 1999-01-12
PT910344E (pt) 2003-09-30
BG64114B1 (bg) 2004-01-30
JO1969B1 (en) 1997-12-15
ID17128A (id) 1997-12-04
CA2258841A1 (en) 1998-01-15
JP2000513727A (ja) 2000-10-17
MY116124A (en) 2003-11-28
IL127364A0 (en) 1999-10-28
HUP9903308A2 (hu) 2000-03-28
TR199802762T2 (xx) 1999-03-22
EP0910344B1 (en) 2003-04-16
HK1021511A1 (en) 2000-06-16
AU731276B2 (en) 2001-03-29
TW473392B (en) 2002-01-21
NO320767B1 (no) 2006-01-23
WO1998001114A1 (en) 1998-01-15
NO986157D0 (no) 1998-12-28
PL188235B1 (pl) 2004-12-31
EA001537B1 (ru) 2001-04-23
SI0910344T1 (en) 2003-08-31
CZ295893B6 (cs) 2005-11-16
HU225115B1 (hu) 2006-06-28
NO986157L (no) 1999-02-01
DK0910344T3 (da) 2003-07-07
CN1131025C (zh) 2003-12-17
BR9710181B1 (pt) 2009-08-11
DE69720995D1 (de) 2003-05-22
ATE237314T1 (de) 2003-05-15
ZA975848B (en) 1999-04-12
DE69720995T2 (de) 2003-11-13
SK284175B6 (sk) 2004-10-05
US5837292A (en) 1998-11-17
BR9710181A (pt) 1999-08-10
CZ699A3 (cs) 1999-04-14
PL330958A1 (en) 1999-06-21

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