MX9706062A - FORMAS DE DOSIFICACION ORAL CONTENIENDO UN ANTIBIOTICO DE beta -LACTAMA. - Google Patents

FORMAS DE DOSIFICACION ORAL CONTENIENDO UN ANTIBIOTICO DE beta -LACTAMA.

Info

Publication number
MX9706062A
MX9706062A MX9706062A MX9706062A MX9706062A MX 9706062 A MX9706062 A MX 9706062A MX 9706062 A MX9706062 A MX 9706062A MX 9706062 A MX9706062 A MX 9706062A MX 9706062 A MX9706062 A MX 9706062A
Authority
MX
Mexico
Prior art keywords
beta
lactam antibiotic
oral dosage
granulate
forms containing
Prior art date
Application number
MX9706062A
Other languages
English (en)
Inventor
Robertus Cornelis Van Koutrik
Gerrit Jan Sijbrands
Original Assignee
Yamanouchi Europ Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Europ Bv filed Critical Yamanouchi Europ Bv
Publication of MX9706062A publication Critical patent/MX9706062A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A61K31/431Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Se proporciona un granulado que contiene 50-99,9% en peso de un antibiotico de beta-lactama soluble en agua, 0-50% en peso de un producto de la celulosa el cual es celulosa microcristalina, celulosa microfina o una mezcla de las mismas, y 0-0,5% en peso de un agente aglutinante para la granulacion en humedo. Se describe un proceso para la preparacion de un granulado que comprende un antibiotico de beta-lactama soluble en agua, cuyo proceso comprende humedecer los componentes del granulado con un líquido esencialmente acuoso sin emplear una cantidad importante de un agente aglutinante para la granulacion en humedo (0-0,5% en peso) y tamizar consecutivamente los granulados humedos y secos a través de un tamiz de por lo menos 0,71 mm. Los granulados se mezclan convenientemente con un producto de celulosa, el cual es celulosa microcristalina, celulosa microfina o una mezcla de las mismas, y uno o más desintegrantes para utilizarse en formas de dosificacion oral rápidamente dispersables, cuando se ponen en un ambiente acuoso. El sabor de dichas formas de dosificacion oral se mejora utilizando una combinacion de agentes edulcorantes y sazonantes. También se proporciona un proceso para la preparacion de dichas formas de dosificacion.
MX9706062A 1995-02-08 1996-02-08 FORMAS DE DOSIFICACION ORAL CONTENIENDO UN ANTIBIOTICO DE beta -LACTAMA. MX9706062A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95200313 1995-02-08
PCT/EP1996/000547 WO1996024337A1 (en) 1995-02-08 1996-02-08 ORAL DOSAGE-FORMS CONTAINING A β-LACTAM ANTIBIOTIC

Publications (1)

Publication Number Publication Date
MX9706062A true MX9706062A (es) 1997-10-31

Family

ID=8220003

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9706062A MX9706062A (es) 1995-02-08 1996-02-08 FORMAS DE DOSIFICACION ORAL CONTENIENDO UN ANTIBIOTICO DE beta -LACTAMA.

Country Status (19)

Country Link
US (1) US5948422A (es)
EP (1) EP0801559B1 (es)
CN (1) CN1125636C (es)
AT (1) ATE216576T1 (es)
AU (1) AU4789696A (es)
BG (1) BG63528B1 (es)
BR (1) BR9607189A (es)
CZ (1) CZ293718B6 (es)
DE (1) DE69620866T2 (es)
DK (1) DK0801559T3 (es)
EA (2) EA000361B1 (es)
ES (1) ES2175073T3 (es)
HU (1) HU227938B1 (es)
MX (1) MX9706062A (es)
NO (1) NO319993B1 (es)
PL (1) PL186386B1 (es)
PT (1) PT801559E (es)
WO (1) WO1996024337A1 (es)
ZA (1) ZA961018B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI225402B (en) 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
EP0912169A2 (en) * 1996-07-16 1999-05-06 Gist-Brocades B.V. $g(b)-LACTAM GRANULES FREE OF ORGANIC SOLVENTS
US6080427A (en) * 1997-04-17 2000-06-27 Bristol-Myers Squibb Company Cefadroxil monohydrate tablet formulation
AU741992B2 (en) * 1998-03-06 2001-12-13 Adare Pharmaceuticals S.R.L. Fast disintegrating tablets
US7399751B2 (en) * 1999-11-04 2008-07-15 Sertoli Technologies, Inc. Production of a biological factor and creation of an immunologically privileged environment using genetically altered Sertoli cells
DE19922537A1 (de) * 1999-05-10 2000-11-16 Roland Bodmeier Darreichungsform zur Applikation in Körperöffnungen
US20040034039A1 (en) * 2000-09-22 2004-02-19 Yoshinori Nakano Solid preparations
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
JP2004522752A (ja) * 2001-02-05 2004-07-29 アール.ピー. シェーラー テクノロジーズ インコーポレイテッド 薬学的活性剤の味を軽減するための方法および組成物
JP4619658B2 (ja) * 2002-03-12 2011-01-26 富山化学工業株式会社 快い味の経口懸濁液および方法
WO2004030673A1 (ja) * 2002-10-02 2004-04-15 Meiji Seika Kaisha, Ltd. 経口吸収性が改善された抗菌性医薬組成物
ES2708552T3 (es) * 2002-12-20 2019-04-10 Niconovum Ab Método para la preparación de un material particulado que contiene nicotina con una celulosa cristalina (en particular MCC)
CA2531022C (en) * 2003-07-03 2014-09-09 Jannette Dufour Compositions containing sertoli cells and myoid cells and use thereof in cellular transplants
US20050089502A1 (en) * 2003-08-21 2005-04-28 Todd Schansberg Effervescent delivery system
US20080255048A1 (en) * 2005-11-17 2008-10-16 Moise Azria Pharmaceutical Composition
AU2007224584A1 (en) 2006-03-16 2007-09-20 Niconovum Ab Improved snuff composition
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
WO2008014470A2 (en) * 2006-07-28 2008-01-31 Sertocell Biotechnology (Us) Corp. Adult sertoli cells and uses thereof
WO2010031552A1 (en) * 2008-09-17 2010-03-25 Niconovum Ab Process for preparing snuff composition
EP2367422A4 (en) * 2008-12-17 2013-01-09 Altheus Therapeutics Inc FORMULAS FOR LAVATION
WO2023204773A1 (en) * 2022-04-20 2023-10-26 Bilim Ilac Sanayii Ve Ticaret A.S. Tablet formulations for the treatment of urinary system infections and method for the preparation of such formulations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3344030A (en) * 1964-06-15 1967-09-26 American Home Prod Reinforced directly compressed nongranulated pharmaceutical crystalline lactose tables
DE2251249A1 (de) * 1972-10-19 1974-05-02 Hoechst Ag Verfahren zur herstellung von penicillin-verbindungen enthaltenden tabletten
DE2251250C3 (de) * 1972-10-19 1981-06-25 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung hochdosierter Antibiotica-Tabletten
DE3887179T2 (de) * 1987-03-02 1994-06-16 Brocades Pharma Bv Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
US5049394A (en) * 1987-09-11 1991-09-17 E. R. Squibb & Sons, Inc. Pharmaceutical composition containing high drug load and method for preparing same
DE68916983T2 (de) * 1988-02-25 1995-01-19 Yamanouchi Europ Bv Verfahren zur Herstellung eines pharmazeutischen Granulats.
US5643591A (en) * 1991-01-16 1997-07-01 Fmc Corporation Solid dosage forms
DE69525151T2 (de) * 1994-04-13 2002-08-14 Res Corp Technologies Inc Methoden zur krankheitsbehandlung unter verwendung von sertoli-zellen und allotransplantat oder xenotransplantat
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin

Also Published As

Publication number Publication date
US5948422A (en) 1999-09-07
DE69620866T2 (de) 2003-02-27
ATE216576T1 (de) 2002-05-15
EP0801559B1 (en) 2002-04-24
EA199900205A1 (ru) 2000-06-26
HU227938B1 (en) 2012-06-28
HUP9801677A2 (hu) 1998-11-30
PL321567A1 (en) 1997-12-08
BG63528B1 (bg) 2002-04-30
PT801559E (pt) 2002-09-30
EA003736B1 (ru) 2003-08-28
AU4789696A (en) 1996-08-27
HUP9801677A3 (en) 1999-05-28
CZ230297A3 (en) 1997-11-12
DE69620866D1 (de) 2002-05-29
WO1996024337A1 (en) 1996-08-15
EP0801559A1 (en) 1997-10-22
ZA961018B (en) 1997-08-08
CN1125636C (zh) 2003-10-29
ES2175073T3 (es) 2002-11-16
EA199700093A1 (ru) 1998-02-26
CZ293718B6 (cs) 2004-07-14
BR9607189A (pt) 1997-11-11
EA000361B1 (ru) 1999-06-24
BG101822A (en) 1998-04-30
DK0801559T3 (da) 2002-06-17
NO973646D0 (no) 1997-08-07
PL186386B1 (pl) 2004-01-30
NO319993B1 (no) 2005-10-10
CN1173816A (zh) 1998-02-18
NO973646L (no) 1997-09-11

Similar Documents

Publication Publication Date Title
MX9706062A (es) FORMAS DE DOSIFICACION ORAL CONTENIENDO UN ANTIBIOTICO DE beta -LACTAMA.
HU206683B (en) Process for producing 1,5-diphenyl-pyrazolo-3-carboxylic acid derivatives and selective herbicide compositions containing them as antidotum
CA2225286A1 (en) A composition comprising an active agent dissolved in a glass-forming carrier and a process for the preparation thereof
HUT43239A (en) Plant protective compositions comprising acryl acid derivatives as active substance and process for preparing the active substances
JO1969B1 (en) Granulation process for the preparation of rapidly dissolving and dissolving compounds containing a high amount of the drug
UA42745C2 (uk) Спосіб виготовлення таблеток, які містять пароксетин, та таблетка, яка містить пароксетин
HUT49366A (en) Process for producing 2',3'-dideoxy-2',2'-difluoronucleosides and pharmaceutical compositions comprising same
HUP9601358A2 (en) Fluoro-phenyl-substituted alkenyl-carboxylic-guanidines, process for producing them, their use as medicines or diagnostica, and pharmaceutical compositions containing them
ATE288271T1 (de) Stabile feste formulierung eines enalaprilsalzes und verfahren zu deren herstellung
HU9601321D0 (en) Substituted (benzyloxy)-carbonyl-guanidine derivatives, process for producing them, their use as pharmaceutical compositions or diagnostica, and pharmaceutical compositions containing them
IL83978A0 (en) Process and compositions containing dihalopyridine derivatives for protecting plants against diseases,certain such novel derivatives and their preparation
HU905725D0 (en) Process for producing 1,4-disubstituted 5-aryl-carbamoyl-4(6)-oxo-6(4)-oxido-pyrimidine-betaine derivatives and anthelmintic preparatives containing these compounds as active substance
ZA901543B (en) Benzoxazolinone derivatives,process for preparing them and pharmaceutical compositions containing them
PL331588A1 (en) Granulated products containing a water-soluble compound and cellulose
HUP9801439A3 (en) Use of beta-d-galactopyranosyl-d-xyloses for the preparation of compositions and solutions intended to the evaluation of intestinal lactase, and production process of the said compds.
FR2787811B1 (fr) Dextrose pulverulent et son procede de preparation
HU913540D0 (en) Process for the protection of plant cultivation by using triazolyl- or imidazolyl-methyl-allyl-alcoholes, and the new compounds used in the process
EP0364601A4 (en) Agent for imparting sustained-release properties to agricultural chemicals, sustained-release agricultural chemicals, and process for their preparation
EP0346908A3 (en) Animal feed and procedure for granulating same
HUP0002767A1 (hu) Szénhidrát alapú enzimgranulátumok
HU895896D0 (en) Process for producing 1-amino-alkyl-3-oxy-4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepin-2-one derivatives and pharmaceutical compositions containing them as active components
TW334424B (en) L-arginine aldehyde derivatives process for preparing them and pharmaceutical composition
ZA828934B (en) Tetrazole derivatives, process for preparing these compounds, and pharmaceutical compositions thereof
HU9303785D0 (en) 2-thienyl-imidazo[2,1-b]benzothiazol-3-acetic acid derivatives, process for producing them and pharmaceutical compositions containing them
TW362019B (en) Stable preparation of sodium 1,4-dimethylisopropylazulene-3-sulfonate and process thereof