ATE216576T1 - Vehrfahren zur herstellung von beta-lactam antibiotikum enthaltenden oralen dosisformen - Google Patents

Vehrfahren zur herstellung von beta-lactam antibiotikum enthaltenden oralen dosisformen

Info

Publication number
ATE216576T1
ATE216576T1 AT96904039T AT96904039T ATE216576T1 AT E216576 T1 ATE216576 T1 AT E216576T1 AT 96904039 T AT96904039 T AT 96904039T AT 96904039 T AT96904039 T AT 96904039T AT E216576 T1 ATE216576 T1 AT E216576T1
Authority
AT
Austria
Prior art keywords
pct
lactam antibiotic
oral dosage
granulate
dosage forms
Prior art date
Application number
AT96904039T
Other languages
English (en)
Inventor
Gerrit Jan Sijbrands
Koutrik Robertus Cornelis Van
Original Assignee
Yamanouchi Europ Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Europ Bv filed Critical Yamanouchi Europ Bv
Application granted granted Critical
Publication of ATE216576T1 publication Critical patent/ATE216576T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
AT96904039T 1995-02-08 1996-02-08 Vehrfahren zur herstellung von beta-lactam antibiotikum enthaltenden oralen dosisformen ATE216576T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95200313 1995-02-08
PCT/EP1996/000547 WO1996024337A1 (en) 1995-02-08 1996-02-08 ORAL DOSAGE-FORMS CONTAINING A β-LACTAM ANTIBIOTIC

Publications (1)

Publication Number Publication Date
ATE216576T1 true ATE216576T1 (de) 2002-05-15

Family

ID=8220003

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96904039T ATE216576T1 (de) 1995-02-08 1996-02-08 Vehrfahren zur herstellung von beta-lactam antibiotikum enthaltenden oralen dosisformen

Country Status (19)

Country Link
US (1) US5948422A (de)
EP (1) EP0801559B1 (de)
CN (1) CN1125636C (de)
AT (1) ATE216576T1 (de)
AU (1) AU4789696A (de)
BG (1) BG63528B1 (de)
BR (1) BR9607189A (de)
CZ (1) CZ293718B6 (de)
DE (1) DE69620866T2 (de)
DK (1) DK0801559T3 (de)
EA (2) EA000361B1 (de)
ES (1) ES2175073T3 (de)
HU (1) HU227938B1 (de)
MX (1) MX9706062A (de)
NO (1) NO319993B1 (de)
PL (1) PL186386B1 (de)
PT (1) PT801559E (de)
WO (1) WO1996024337A1 (de)
ZA (1) ZA961018B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
AU4011397A (en) 1996-07-16 1998-02-09 Gist-Brocades B.V. Beta-lactam granules free of organic solvents
US6080427A (en) * 1997-04-17 2000-06-27 Bristol-Myers Squibb Company Cefadroxil monohydrate tablet formulation
ATE219658T1 (de) * 1998-03-06 2002-07-15 Eurand Int Schnell zerfallende tablette
US7399751B2 (en) * 1999-11-04 2008-07-15 Sertoli Technologies, Inc. Production of a biological factor and creation of an immunologically privileged environment using genetically altered Sertoli cells
DE19922537A1 (de) * 1999-05-10 2000-11-16 Roland Bodmeier Darreichungsform zur Applikation in Körperöffnungen
AU2001288102A1 (en) * 2000-09-22 2002-04-02 Takeda Chemical Industries Ltd. Solid preparations
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
CZ20032138A3 (cs) * 2001-02-05 2005-03-16 R. P. Scherer Technologies, Inc. Způsoby a prostředky pro zeslabení chuti farmaceuticky aktivních činidel
RU2190403C1 (ru) * 2001-09-27 2002-10-10 Нестерук Владимир Викторович Фармацевтическая композиция, обладающая антибактериальным действием, и способ ее получения
CA2478411C (en) * 2002-03-12 2010-09-28 Bristol-Myers Squibb Company Palatable oral suspension and method
EP1555024B1 (de) * 2002-10-02 2010-09-29 Meiji Seika Kaisha Ltd. Antibakterielle medizinische zusammensetzung mit erhöhtem oralem absorptionsvermögen
ATE359075T1 (de) * 2002-12-20 2007-05-15 Niconovum Ab Chemisch und physikalisch stabiles teilchenförmiges material enthaltend nikotin und microcrystalline cellulose
WO2005018540A2 (en) * 2003-07-03 2005-03-03 Jannette Dufour Compositions containing sertoli cells and myoid cells and use thereof in cellular transplants
US20050089502A1 (en) * 2003-08-21 2005-04-28 Todd Schansberg Effervescent delivery system
US20080255048A1 (en) * 2005-11-17 2008-10-16 Moise Azria Pharmaceutical Composition
JP5694645B2 (ja) 2006-03-16 2015-04-01 ニコノヴァム エービーＮｉｃｏｎｏｖｕｍ Ａｂ 改善された嗅ぎたばこ組成物
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
AU2007278850B2 (en) * 2006-07-28 2013-06-06 Sertocell Biotechnology (Us) Corp. Adult sertoli cells and uses thereof
WO2010031552A1 (en) * 2008-09-17 2010-03-25 Niconovum Ab Process for preparing snuff composition
AU2009333303A1 (en) * 2008-12-17 2011-08-11 Altheus Therapeutics, Inc. Enema formulations
WO2023204773A1 (en) * 2022-04-20 2023-10-26 Bilim Ilac Sanayii Ve Ticaret A.S. Tablet formulations for the treatment of urinary system infections and method for the preparation of such formulations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3344030A (en) * 1964-06-15 1967-09-26 American Home Prod Reinforced directly compressed nongranulated pharmaceutical crystalline lactose tables
DE2251249A1 (de) * 1972-10-19 1974-05-02 Hoechst Ag Verfahren zur herstellung von penicillin-verbindungen enthaltenden tabletten
DE2251250C3 (de) * 1972-10-19 1981-06-25 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung hochdosierter Antibiotica-Tabletten
DE3887179T2 (de) * 1987-03-02 1994-06-16 Brocades Pharma Bv Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
US5049394A (en) * 1987-09-11 1991-09-17 E. R. Squibb & Sons, Inc. Pharmaceutical composition containing high drug load and method for preparing same
EP0330284B1 (de) * 1988-02-25 1994-07-27 Yamanouchi Europe B.V. Verfahren zur Herstellung eines pharmazeutischen Granulats
US5643591A (en) * 1991-01-16 1997-07-01 Fmc Corporation Solid dosage forms
US5725854A (en) * 1994-04-13 1998-03-10 Research Corporation Technologies, Inc. Methods of treating disease using sertoli cells an allografts or xenografts
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin

Also Published As

Publication number Publication date
EA199700093A1 (ru) 1998-02-26
HU227938B1 (en) 2012-06-28
EA199900205A1 (ru) 2000-06-26
WO1996024337A1 (en) 1996-08-15
NO973646D0 (no) 1997-08-07
AU4789696A (en) 1996-08-27
CN1125636C (zh) 2003-10-29
BG101822A (en) 1998-04-30
NO319993B1 (no) 2005-10-10
BG63528B1 (bg) 2002-04-30
PT801559E (pt) 2002-09-30
PL321567A1 (en) 1997-12-08
EP0801559A1 (de) 1997-10-22
BR9607189A (pt) 1997-11-11
ES2175073T3 (es) 2002-11-16
EA003736B1 (ru) 2003-08-28
CN1173816A (zh) 1998-02-18
US5948422A (en) 1999-09-07
MX9706062A (es) 1997-10-31
EA000361B1 (ru) 1999-06-24
DK0801559T3 (da) 2002-06-17
DE69620866T2 (de) 2003-02-27
HUP9801677A2 (hu) 1998-11-30
HUP9801677A3 (en) 1999-05-28
NO973646L (no) 1997-09-11
DE69620866D1 (de) 2002-05-29
CZ230297A3 (en) 1997-11-12
PL186386B1 (pl) 2004-01-30
CZ293718B6 (cs) 2004-07-14
ZA961018B (en) 1997-08-08
EP0801559B1 (de) 2002-04-24

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