BE2011C002I2 - Aminocyclohexyl ether compounds and uses thereof - Google Patents
Aminocyclohexyl ether compounds and uses thereofInfo
- Publication number
- BE2011C002I2 BE2011C002I2 BE2011C002C BE2011C002C BE2011C002I2 BE 2011C002 I2 BE2011C002 I2 BE 2011C002I2 BE 2011C002 C BE2011C002 C BE 2011C002C BE 2011C002 C BE2011C002 C BE 2011C002C BE 2011C002 I2 BE2011C002 I2 BE 2011C002I2
- Authority
- BE
- Belgium
- Prior art keywords
- ether compounds
- compounds
- aminocyclohexyl ether
- compositions
- formula
- Prior art date
Links
- MHWUUEBDNXLKJI-UHFFFAOYSA-N 1-(1-aminocyclohexyl)oxycyclohexan-1-amine Chemical class C1CCCCC1(N)OC1(N)CCCCC1 MHWUUEBDNXLKJI-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000036592 analgesia Effects 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 230000006793 arrhythmia Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000002690 local anesthesia Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
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- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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Applications Claiming Priority (4)
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US8034798P | 1998-04-01 | 1998-04-01 | |
US11895499P | 1999-02-05 | 1999-02-05 | |
PCT/CA1999/000280 WO1999050225A1 (fr) | 1998-04-01 | 1999-04-01 | Composes d'aminocyclohexyl ether et leurs applications |
EP99911550A EP1087934B1 (fr) | 1998-04-01 | 1999-04-01 | Composes d'aminocyclohexyl ether et leurs applications |
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BE2011C002C BE2011C002I2 (en) | 1998-04-01 | 2011-01-20 | Aminocyclohexyl ether compounds and uses thereof |
Country Status (33)
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US (5) | US7101877B2 (fr) |
EP (2) | EP1087934B1 (fr) |
JP (2) | JP4334766B2 (fr) |
KR (1) | KR100631299B1 (fr) |
CN (1) | CN1217918C (fr) |
AT (1) | ATE260240T1 (fr) |
AU (1) | AU751772C (fr) |
BE (1) | BE2011C002I2 (fr) |
BR (1) | BRPI9909282B8 (fr) |
CA (1) | CA2326777C (fr) |
CY (1) | CY2010018I2 (fr) |
CZ (1) | CZ302147B6 (fr) |
DE (2) | DE69915063T2 (fr) |
DK (1) | DK1087934T3 (fr) |
EE (1) | EE04548B1 (fr) |
ES (1) | ES2217742T3 (fr) |
FR (1) | FR10C0057I2 (fr) |
HK (1) | HK1038345A1 (fr) |
HU (1) | HU229993B1 (fr) |
ID (1) | ID27178A (fr) |
IL (1) | IL138719A0 (fr) |
IS (1) | IS2648B (fr) |
LU (1) | LU91761I2 (fr) |
MX (1) | MXPA00009593A (fr) |
NO (2) | NO321130B1 (fr) |
NZ (1) | NZ507169A (fr) |
PL (1) | PL197293B1 (fr) |
PT (1) | PT1087934E (fr) |
RO (1) | RO121028B1 (fr) |
RU (1) | RU2252933C2 (fr) |
SK (1) | SK285908B6 (fr) |
TR (1) | TR200002796T2 (fr) |
WO (1) | WO1999050225A1 (fr) |
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PL227937B1 (pl) | 2003-05-02 | 2018-01-31 | Cardiome Pharma Corp | Sposób wytwarzania związku typu eteru aminocykloheksylowego, związek typu eteru aminocykloheksylowego, jego kompozycja, sposób modulowania aktywności kanałów jonowych, oraz zastosowanie związku typu eteru aminocykloheksylowego do wytwarzania leku |
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US8058304B2 (en) | 2004-04-01 | 2011-11-15 | Cardiome Pharma Corp. | Merged ion channel modulating compounds and uses thereof |
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- 1999-04-01 RU RU2000127720/04A patent/RU2252933C2/ru active
- 1999-04-01 TR TR2000/02796T patent/TR200002796T2/xx unknown
- 1999-04-01 PL PL343425A patent/PL197293B1/pl unknown
- 1999-04-01 ES ES99911550T patent/ES2217742T3/es not_active Expired - Lifetime
- 1999-04-01 EP EP04002165A patent/EP1422217A3/fr not_active Withdrawn
- 1999-04-01 EE EEP200000583A patent/EE04548B1/xx active Protection Beyond IP Right Term
- 1999-04-01 CZ CZ20003485A patent/CZ302147B6/cs not_active IP Right Cessation
- 1999-04-01 WO PCT/CA1999/000280 patent/WO1999050225A1/fr not_active Application Discontinuation
- 1999-04-01 CN CN998066826A patent/CN1217918C/zh not_active Expired - Lifetime
- 1999-04-01 DE DE122010000052C patent/DE122010000052I1/de active Pending
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- 2007-11-21 US US11/944,282 patent/US7534790B2/en not_active Expired - Lifetime
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