FR2564464B1 - Ethers aminocyclopentyliques, leur procede de fabrication et composition pharmaceutique en resultant - Google Patents

Ethers aminocyclopentyliques, leur procede de fabrication et composition pharmaceutique en resultant

Info

Publication number
FR2564464B1
FR2564464B1 FR8507483A FR8507483A FR2564464B1 FR 2564464 B1 FR2564464 B1 FR 2564464B1 FR 8507483 A FR8507483 A FR 8507483A FR 8507483 A FR8507483 A FR 8507483A FR 2564464 B1 FR2564464 B1 FR 2564464B1
Authority
FR
France
Prior art keywords
aminocyclopentyl
ethers
manufacturing
pharmaceutical composition
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8507483A
Other languages
English (en)
Other versions
FR2564464A1 (fr
Inventor
Christopher John Wallis
Harry Finch
David Edmund Bays
Peter Hallett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848412774A external-priority patent/GB8412774D0/en
Priority claimed from GB848423083A external-priority patent/GB8423083D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FR2564464A1 publication Critical patent/FR2564464A1/fr
Application granted granted Critical
Publication of FR2564464B1 publication Critical patent/FR2564464B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
FR8507483A 1984-05-18 1985-05-17 Ethers aminocyclopentyliques, leur procede de fabrication et composition pharmaceutique en resultant Expired FR2564464B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848412774A GB8412774D0 (en) 1984-05-18 1984-05-18 Carbocyclic compounds
GB848423083A GB8423083D0 (en) 1984-09-12 1984-09-12 Carbocyclic compounds

Publications (2)

Publication Number Publication Date
FR2564464A1 FR2564464A1 (fr) 1985-11-22
FR2564464B1 true FR2564464B1 (fr) 1988-09-02

Family

ID=26287761

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8507483A Expired FR2564464B1 (fr) 1984-05-18 1985-05-17 Ethers aminocyclopentyliques, leur procede de fabrication et composition pharmaceutique en resultant

Country Status (14)

Country Link
US (1) US4880800A (fr)
AU (1) AU580777B2 (fr)
BE (1) BE902450A (fr)
CA (1) CA1243020A (fr)
CH (1) CH667646A5 (fr)
DE (1) DE3517901A1 (fr)
DK (1) DK218985A (fr)
FR (1) FR2564464B1 (fr)
GB (1) GB2159816B (fr)
IL (1) IL75230A (fr)
IT (1) IT1180748B (fr)
NL (1) NL8501429A (fr)
NZ (1) NZ212108A (fr)
SE (1) SE8502455L (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5039673A (en) * 1987-06-22 1991-08-13 Glaxo Group Limited Aminocyclopentyl ethers and their preparation and pharmaceutical formulation
PT87776B (pt) * 1987-06-22 1992-10-30 Glaxo Group Ltd Processo para a preparacao de eteres aminociclopentilicos e composicoes farmaceuticas que os contem
KR100631299B1 (ko) 1998-04-01 2006-10-09 카디오메 파마 코포레이션 아미노사이클로헥실 에테르 화합물 및 이를 포함하는 약제학적 조성물
WO2000047547A2 (fr) * 1999-02-12 2000-08-17 Nortran Pharmaceuticals Inc. Composes d'amines cycloalkyles et utilisation de ceux-ci
US6979685B1 (en) 1999-02-12 2005-12-27 Cardiome Pharma Corp. Cycloalkyl amine compounds and uses thereof
US7507545B2 (en) 1999-03-31 2009-03-24 Cardiome Pharma Corp. Ion channel modulating activity method
US7057053B2 (en) 2000-10-06 2006-06-06 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
US7524879B2 (en) 2000-10-06 2009-04-28 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
US7345086B2 (en) 2003-05-02 2008-03-18 Cardiome Pharma Corp. Uses of ion channel modulating compounds
US20090041841A1 (en) * 2003-05-02 2009-02-12 Cardiome Pharma Corp. Controlled release tablet formulations for the prevention of arrhythmias
CA2524323C (fr) 2003-05-02 2012-05-15 Cardiome Pharma Corp. Composes a base d'aminocyclohexyle-ether et leurs utilisations
WO2005018635A2 (fr) 2003-08-07 2005-03-03 Cardiome Pharma Corp. Activite i modulant des canaux ioniques
US7345087B2 (en) 2003-10-31 2008-03-18 Cardiome Pharma Corp. Aminocyclohexyl ether compounds and uses thereof
WO2005097087A2 (fr) 2004-04-01 2005-10-20 Cardiome Pharma Corp. Composes combines de modulation du canal ionique et utilisation desdits composes
US7977373B2 (en) 2004-04-01 2011-07-12 Cardiome Pharma Corp. Prodrugs of ion channel modulating compounds and uses thereof
JP5583325B2 (ja) 2004-11-08 2014-09-03 カーディオム ファーマ コーポレイション イオンチャネル調節化合物の投与レジメ

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2658401A1 (de) * 1976-12-23 1978-07-06 Merck Patent Gmbh Cyclopentan-1-amine, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
US4265891A (en) * 1978-07-11 1981-05-05 Glaxo Group Limited Prostanoid compounds and compositions
AU542949B2 (en) * 1980-01-09 1985-03-28 Glaxo Group Limited Prostanoid compounds
US4345984A (en) * 1981-03-02 1982-08-24 The Procter & Gamble Company Novel prostaglandin analogues and process for making same
GB8307099D0 (en) * 1983-03-15 1983-04-20 Glaxo Group Ltd Carbocyclic compounds
KR850002476A (ko) * 1983-09-06 1985-05-13 비 에이 뉴샘 아미노사이클로펜탄의 제조방법

Also Published As

Publication number Publication date
GB8512591D0 (en) 1985-06-19
CA1243020A (fr) 1988-10-11
DK218985A (da) 1985-11-19
IT8548093A1 (it) 1986-11-17
NZ212108A (en) 1988-10-28
SE8502455L (sv) 1985-11-19
IT8548093A0 (it) 1985-05-17
BE902450A (fr) 1985-11-18
SE8502455D0 (sv) 1985-05-17
US4880800A (en) 1989-11-14
IT1180748B (it) 1987-09-23
DE3517901A1 (de) 1985-12-12
AU580777B2 (en) 1989-02-02
NL8501429A (nl) 1985-12-16
GB2159816B (en) 1989-05-24
CH667646A5 (de) 1988-10-31
IL75230A0 (en) 1985-09-29
IL75230A (en) 1989-07-31
AU4262585A (en) 1985-11-21
FR2564464A1 (fr) 1985-11-22
GB2159816A (en) 1985-12-11
DK218985D0 (da) 1985-05-17

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Legal Events

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ST Notification of lapse