FR2581871B1 - Solutions a base de phenytoine, leur procede de preparation et leur application pharmaceutique - Google Patents

Solutions a base de phenytoine, leur procede de preparation et leur application pharmaceutique

Info

Publication number
FR2581871B1
FR2581871B1 FR868603981A FR8603981A FR2581871B1 FR 2581871 B1 FR2581871 B1 FR 2581871B1 FR 868603981 A FR868603981 A FR 868603981A FR 8603981 A FR8603981 A FR 8603981A FR 2581871 B1 FR2581871 B1 FR 2581871B1
Authority
FR
France
Prior art keywords
phenytoin
preparation process
based solutions
pharmaceutical application
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR868603981A
Other languages
English (en)
Other versions
FR2581871A1 (fr
Inventor
Mahdi B Fawzi
Anne K Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of FR2581871A1 publication Critical patent/FR2581871A1/fr
Application granted granted Critical
Publication of FR2581871B1 publication Critical patent/FR2581871B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR868603981A 1985-05-20 1986-03-20 Solutions a base de phenytoine, leur procede de preparation et leur application pharmaceutique Expired - Fee Related FR2581871B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/735,932 US4642316A (en) 1985-05-20 1985-05-20 Parenteral phenytoin preparations

Publications (2)

Publication Number Publication Date
FR2581871A1 FR2581871A1 (fr) 1986-11-21
FR2581871B1 true FR2581871B1 (fr) 1990-05-11

Family

ID=24957819

Family Applications (1)

Application Number Title Priority Date Filing Date
FR868603981A Expired - Fee Related FR2581871B1 (fr) 1985-05-20 1986-03-20 Solutions a base de phenytoine, leur procede de preparation et leur application pharmaceutique

Country Status (18)

Country Link
US (1) US4642316A (fr)
JP (1) JPS61268618A (fr)
AU (1) AU595790B2 (fr)
BE (1) BE904476A (fr)
CA (1) CA1268119A (fr)
CH (1) CH668594A5 (fr)
DE (1) DE3610330A1 (fr)
DK (1) DK100786A (fr)
ES (1) ES8707195A1 (fr)
FR (1) FR2581871B1 (fr)
GB (1) GB2175203B (fr)
IT (1) IT1190282B (fr)
LU (1) LU86383A1 (fr)
NL (1) NL8600899A (fr)
NZ (1) NZ215783A (fr)
PH (1) PH22922A (fr)
SE (1) SE8600998L (fr)
ZA (1) ZA862094B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3828156A1 (de) * 1988-08-19 1990-02-22 Astrapin Pharmazeutische Praep Stabile waessrige loesung von fluorouracil
AU8479998A (en) * 1997-07-22 1999-02-16 Warner-Lambert Company Lyophilized fosphenytoin sodium for parenteral use
US6245917B1 (en) 1998-03-20 2001-06-12 Warner-Lambert Company Crystalline sodium phenytoin monohydrate
US6274168B1 (en) 1999-02-23 2001-08-14 Mylan Pharmaceuticals Inc. Phenytoin sodium pharmaceutical compositions
US20060222713A1 (en) * 2002-12-16 2006-10-05 Deepak Murpani Extended release pharmaceutical composition of phenytoin sodium
NZ599464A (en) 2005-02-03 2014-03-28 Topotarget Uk Ltd Combination therapies using hdac inhibitors
DE102005019393A1 (de) * 2005-04-25 2006-10-26 Basell Polyolefine Gmbh Polyethylenformmassen für Spritzgussanwendungen
AU2012213940B2 (en) * 2005-05-13 2015-03-26 Topotarget Uk Limited Pharmaceutical formulations of HDAC inhibitors
JP5108750B2 (ja) * 2005-05-13 2012-12-26 トポターゲット ユーケー リミテッド Ｈｄａｃ阻害剤の医薬製剤
WO2007054719A2 (fr) 2005-11-10 2007-05-18 Topotarget Uk Limited Inhibiteurs d'histone desacetylase (hdac) pour le traitement du cancer
CA2632198C (fr) * 2005-12-05 2013-10-01 Taro Pharmaceuticals North America, Inc. Preparation pharmaceutique contenant de la phenytoine sodium et du stearate de magnesium
MX2010003230A (es) * 2007-09-25 2010-04-07 Topotarget Uk Ltd Metodos para la sintesis de ciertos compuestos de acido hidroxamico.
ES2536208T3 (es) * 2008-03-07 2015-05-21 Onxeo Dk, Branch Of Onxeo S.A., France Métodos de tratamiento que emplean infusión continua prolongada de Belinostat
GB0900555D0 (en) * 2009-01-14 2009-02-11 Topotarget As New methods
SG10201505101VA (en) * 2009-05-19 2015-07-30 Neuroderm Ltd Compositions For Continuous Administration Of Dopa Decarboxylase Inhibitors
HUE037005T2 (hu) 2010-11-15 2018-08-28 Neuroderm Ltd L-dopának, dopa dekarboxiláz inhibitoroknak, katechol-O-metil transzferáz inhibitoroknak és ezekhez szolgáló kompozícióknak folyamatos bevezetése
WO2012082995A1 (fr) 2010-12-15 2012-06-21 Nektar Therapeutics Composés d'hydantoïne contenant un oligomère
ES2715028T3 (es) 2012-06-05 2019-05-31 Neuroderm Ltd Composiciones que comprenden apomorfina y ácidos orgánicos y sus usos
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
US10022320B2 (en) 2014-03-13 2018-07-17 Neuroderm, Ltd. Dopa decarboxylase inhibitor compositions
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
WO2023205615A1 (fr) * 2022-04-18 2023-10-26 ISHA Therapeutics LLC Compositions de film antimicrobien à dissolution orale et leurs méthodes d'utilisation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3749779A (en) * 1970-08-27 1973-07-31 American Home Prod Stable solutions of sodium diphenylhydantoin
JPS5221575B2 (fr) * 1972-03-18 1977-06-11
US4260769A (en) * 1977-04-22 1981-04-07 Interx Research Corporation 5,5-Diphenylhydantoins
US4163058A (en) * 1977-04-22 1979-07-31 Interx Research Corporation Derivatives of 5,5-diphenylhydantoin exhibiting enhanced solubility and the therapeutic use thereof

Also Published As

Publication number Publication date
GB2175203A (en) 1986-11-26
DE3610330A1 (de) 1986-11-20
SE8600998D0 (sv) 1986-03-05
ES555143A0 (es) 1987-07-16
FR2581871A1 (fr) 1986-11-21
CA1268119A (fr) 1990-04-24
DK100786A (da) 1986-11-21
IT8647936A0 (it) 1986-04-24
SE8600998L (sv) 1986-11-21
PH22922A (en) 1989-01-24
NZ215783A (en) 1989-01-27
US4642316A (en) 1987-02-10
GB8607383D0 (en) 1986-04-30
LU86383A1 (fr) 1986-09-02
GB2175203B (en) 1988-09-14
NL8600899A (nl) 1986-12-16
ZA862094B (en) 1986-11-26
JPS61268618A (ja) 1986-11-28
BE904476A (fr) 1986-09-24
AU5441286A (en) 1986-11-27
ES8707195A1 (es) 1987-07-16
DK100786D0 (da) 1986-03-05
CH668594A5 (fr) 1989-01-13
IT1190282B (it) 1988-02-16
AU595790B2 (en) 1990-04-12

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Legal Events

Date Code Title Description
ST Notification of lapse