|
US4642316A
(en)
*
|
1985-05-20 |
1987-02-10 |
Warner-Lambert Company |
Parenteral phenytoin preparations
|
|
US6071923A
(en)
*
|
1994-09-16 |
2000-06-06 |
Bar-Ilan University |
Retinoyloxy aryl-substituted alkylene butyrates useful for the treatment of cancer and other proliferative diseases
|
|
HUP0103985A2
(en)
*
|
1998-10-13 |
2002-02-28 |
Fujisawa Pharmaceutical Co., Ltd. |
Cyclic tetrapeptide and its use
|
|
US20070148228A1
(en)
*
|
1999-02-22 |
2007-06-28 |
Merrion Research I Limited |
Solid oral dosage form containing an enhancer
|
|
KR100816572B1
(en)
*
|
1999-04-28 |
2008-03-24 |
보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 |
Anti-VEF antibody and pharmaceutical composition comprising the same
|
|
KR20100035666A
(en)
*
|
1999-11-23 |
2010-04-05 |
메틸진 인크. |
Inhibitors of histone deacetylase
|
|
ATE430567T1
(en)
*
|
2000-09-29 |
2009-05-15 |
Topotarget Uk Ltd |
CARBAMINIC ACID DERIVATIVES CONTAINING AN AMIDE GROUP FOR THE TREATMENT OF MALARIA
|
|
GB0023983D0
(en)
*
|
2000-09-29 |
2000-11-15 |
Prolifix Ltd |
Therapeutic compounds
|
|
EP2292593A3
(en)
*
|
2000-09-29 |
2011-05-25 |
TopoTarget UK Limited |
Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors
|
|
WO2002055742A2
(en)
*
|
2001-01-09 |
2002-07-18 |
Novartis Ag |
Rapid method for screening compounds for in vivo activity
|
|
JPWO2002074298A1
(en)
*
|
2001-03-21 |
2004-07-08 |
小野薬品工業株式会社 |
IL-6 production inhibitor
|
|
CN101284773A
(en)
*
|
2001-08-09 |
2008-10-15 |
小野药品工业株式会社 |
Carboxylic acid derivative compounds and drugs comprising these compounds as the active ingredient
|
|
US6897220B2
(en)
*
|
2001-09-14 |
2005-05-24 |
Methylgene, Inc. |
Inhibitors of histone deacetylase
|
|
CA2467629A1
(en)
*
|
2001-11-20 |
2003-05-30 |
Oncomedx, Inc. |
Methods for evaluating drug-resistance gene expression in the cancer patient
|
|
PL215159B1
(en)
*
|
2002-01-11 |
2013-10-31 |
Matthias Rath |
A nutrient pharmaceutical formulation comprising polyphenols and use in treatment of cancer
|
|
EP1482962A4
(en)
*
|
2002-02-15 |
2009-12-23 |
Sloan Kettering Inst Cancer |
METHOD FOR THE TREATMENT OF TRX-MEDIATED ILLNESSES
|
|
US20050288227A1
(en)
*
|
2002-02-15 |
2005-12-29 |
Marks Paul A |
Use of thioredoxin measurements for diagnostics and treatments
|
|
EP1487426B1
(en)
*
|
2002-03-04 |
2012-08-22 |
Sloan-kettering Institute For Cancer Research |
Methods of inducing terminal differentiation
|
|
US20040132825A1
(en)
*
|
2002-03-04 |
2004-07-08 |
Bacopoulos Nicholas G. |
Methods of treating cancer with HDAC inhibitors
|
|
US20070060614A1
(en)
*
|
2002-03-04 |
2007-03-15 |
Bacopoulos Nicholas G |
Methods of treating cancer with hdac inhibitors
|
|
US7148257B2
(en)
*
|
2002-03-04 |
2006-12-12 |
Merck Hdac Research, Llc |
Methods of treating mesothelioma with suberoylanilide hydroxamic acid
|
|
US7495022B2
(en)
*
|
2002-04-11 |
2009-02-24 |
Sk Chemicals Co., Ltd. |
α,β-unsaturated hydroxamic acid derivatives and their use as histone deacetylase inhibitors
|
|
JP2005530734A
(en)
*
|
2002-04-15 |
2005-10-13 |
スローン − ケッタリング インスティチュート フォー キャンサー リサーチ |
Combination therapy for the treatment of cancer
|
|
US8883148B2
(en)
*
|
2002-04-26 |
2014-11-11 |
Asan Laboratories Company (Cayman), Limited |
Prevention of joint destruction
|
|
AU2003221570A1
(en)
*
|
2002-05-01 |
2003-11-17 |
Sarissa Inc. |
Antisense oligonucleotides for identifying drug targets and enhancing cancer therapies
|
|
US20080004311A1
(en)
*
|
2002-11-12 |
2008-01-03 |
Alcon, Inc. |
Histone deacetylase inhibitors for treating degenerative diseases of the eye
|
|
WO2004064727A2
(en)
*
|
2003-01-16 |
2004-08-05 |
Georgetown University |
Method of cancer treatment using hdac inhibitors
|
|
US7169801B2
(en)
*
|
2003-03-17 |
2007-01-30 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
US7606215B2
(en)
*
|
2003-04-07 |
2009-10-20 |
Paul Poniatowski |
Audio/visual information dissemination system
|
|
US20040220242A1
(en)
*
|
2003-05-02 |
2004-11-04 |
Leland Shapiro |
Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide induced clinical conditions
|
|
EP1491188A1
(en)
*
|
2003-06-25 |
2004-12-29 |
G2M Cancer Drugs AG |
Topical use of valproic acid for the prevention or treatment of skin disorders
|
|
PT1663194E
(en)
*
|
2003-08-26 |
2010-07-06 |
Merck Hdac Res Llc |
Use of saha for treating mesothelioma
|
|
DE602004004571T2
(en)
*
|
2003-08-28 |
2007-11-08 |
Roche Diagnostics Gmbh |
Dependence of symptom-free survival of 5-FU treated colorectal cancer patients on the ratio of mRNA expression levels from thymidine phosphorylase and dihydropyrimidine dehydrogenase
|
|
JP2007511211A
(en)
*
|
2003-11-14 |
2007-05-10 |
ホルム,ペル・ゾンネ |
New use of adenovirus and nucleic acid encoding it
|
|
WO2005052143A2
(en)
*
|
2003-11-14 |
2005-06-09 |
Per Sonne Holm |
Novel adenoviruses, nucleic acids that code for the same and the use of said viruses
|
|
GB0401876D0
(en)
*
|
2004-01-28 |
2004-03-03 |
Vereniging Het Nl Kanker I |
New use for cancer antigen
|
|
EP1725873B1
(en)
*
|
2004-02-27 |
2009-07-22 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Pharmacodynamic assays using flow cytometry.
|
|
ATE399539T1
(en)
*
|
2004-04-30 |
2008-07-15 |
Topotarget Germany Ag |
TWO-PHASE RELEASE FORMULATION CONTAINING HISTONE DEACETYLASE INHIBITOR
|
|
EP1787657A1
(en)
*
|
2004-08-06 |
2007-05-23 |
Ono Pharmaceutical Co., Ltd. |
Therapeutic agent for psychoneurotic disease
|
|
CN101001851B
(en)
*
|
2004-08-09 |
2011-04-20 |
安斯泰来制药有限公司 |
Hydroxyamide compounds having activity as inhibitors of histone deacetylase (HDAC)
|
|
WO2006060382A2
(en)
*
|
2004-11-30 |
2006-06-08 |
Trustees Of The University Of Pennsylvania |
Use of hdac and/or dnmt inhibitors for treatment of ischemic injury
|
|
CA2610360A1
(en)
*
|
2004-12-31 |
2006-07-06 |
Per Sonne Holm |
E1-minus adenoviruses and use thereof
|
|
KR101346886B1
(en)
*
|
2005-01-21 |
2014-01-02 |
아스텍스 테라퓨틱스 리미티드 |
Pharmaceutical compounds
|
|
CA2596210C
(en)
*
|
2005-02-03 |
2014-07-08 |
Topotarget Uk Limited |
Combination therapies using hdac inhibitors
|
|
US20060229237A1
(en)
*
|
2005-04-07 |
2006-10-12 |
Yih-Lin Chung |
Treatment of gastrointestinal distress
|
|
GB0509225D0
(en)
*
|
2005-05-05 |
2005-06-15 |
Chroma Therapeutics Ltd |
Inhibitors of enzymatic activity
|
|
US8835501B2
(en)
*
|
2005-05-13 |
2014-09-16 |
Topotarget Uk Limited |
Pharmaceutical formulations of HDAC inhibitors
|
|
EP1743654A1
(en)
*
|
2005-07-15 |
2007-01-17 |
TopoTarget Germany AG |
Use of inhibitors of histone deacetylases in combination with NSAID for the therapy of cancer and/or inflammatory diseases
|
|
WO2007024574A2
(en)
*
|
2005-08-19 |
2007-03-01 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Topical formulations of histone deacetylase inhibitors and methods of using the same
|
|
BRPI0615948A2
(en)
*
|
2005-09-07 |
2011-05-31 |
Plexxikon Inc |
ppar active compound, its composition, its kit and its use
|
|
WO2007031091A2
(en)
*
|
2005-09-15 |
2007-03-22 |
Santaris Pharma A/S |
Rna antagonist compounds for the modulation of p21 ras expression
|
|
WO2007054719A2
(en)
|
2005-11-10 |
2007-05-18 |
Topotarget Uk Limited |
Histone deacetylase (hdac) inhibitors (pxdlol) for the treatment of cancer alone or in combination with chemotherapeutic agent
|
|
US8445198B2
(en)
*
|
2005-12-01 |
2013-05-21 |
Medical Prognosis Institute |
Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy
|
|
WO2007096393A1
(en)
*
|
2006-02-22 |
2007-08-30 |
4Sc Ag |
Indolopyridines as eg5 kinesin modulators
|
|
JP2009527534A
(en)
*
|
2006-02-22 |
2009-07-30 |
4エスツェー アクチェンゲゼルシャフト |
Indropyridine as an EG5 kinesin modulator
|
|
WO2007109178A2
(en)
*
|
2006-03-16 |
2007-09-27 |
Pharmacyclics, Inc. |
Indole derivatives as inhibitors of histone deacetylase
|
|
EP1839656A1
(en)
*
|
2006-03-31 |
2007-10-03 |
TopoTarget Germany AG |
Use of valproic acid for the topical treatment of mild to moderate acne vulgaris
|
|
WO2007129062A1
(en)
*
|
2006-05-08 |
2007-11-15 |
Astex Therapeutics Limited |
Pharmaceutical combinations of diazole derivatives for cancer treatment
|
|
US20070292512A1
(en)
*
|
2006-06-09 |
2007-12-20 |
Merrion Research Ii Limited |
Solid Oral Dosage Form Containing an Enhancer
|
|
WO2008011603A2
(en)
*
|
2006-07-20 |
2008-01-24 |
Wisconsin Alumni Research Foundation |
Modulating notch1 signaling pathway for treating neuroendocrine tumors
|
|
WO2008058287A1
(en)
*
|
2006-11-10 |
2008-05-15 |
Syndax Pharmaceuticals, Inc. |
COMBINATION OF ERα+ LIGANDS AND HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF CANCER
|
|
US8796330B2
(en)
*
|
2006-12-19 |
2014-08-05 |
Methylgene Inc. |
Inhibitors of histone deacetylase and prodrugs thereof
|
|
WO2008094319A2
(en)
*
|
2007-02-01 |
2008-08-07 |
The Board Of Regents Of The University Of Texas Sytem |
Methods and compositions of trail-death receptor agonists/activators
|
|
US8012695B2
(en)
*
|
2007-02-14 |
2011-09-06 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions relating to promoter regulation by MUC1 and KLF proteins
|
|
WO2008116163A1
(en)
*
|
2007-03-22 |
2008-09-25 |
Oregon Health & Science University |
Therapeutic drug combinations for treatment of b-cell malignancies
|
|
WO2008136838A1
(en)
*
|
2007-05-04 |
2008-11-13 |
Trustees Of Dartmouth College |
Novel amide derivatives of cddo and methods of use thereof
|
|
EP2359828A1
(en)
*
|
2007-06-06 |
2011-08-24 |
University of Maryland, Baltimore |
HDAC inhibitors and hormone targeted drugs for the treatment of cancer
|
|
US20090246198A1
(en)
*
|
2008-03-31 |
2009-10-01 |
Takeda Pharmaceutical Company Limited |
Mapk/erk kinase inhibitors and methods of use thereof
|
|
US20090270497A1
(en)
*
|
2008-04-24 |
2009-10-29 |
Pharmacyclics, Inc. |
Treatment of Non-Localized Inflammation with pan-HDAC Inhibitors
|
|
WO2009137649A2
(en)
*
|
2008-05-07 |
2009-11-12 |
The Trustees Of The University Of Pennsylvania |
Methods for treating thyroid cancer
|