BE2011C002I2 - Aminocyclohexyl ether compounds and uses thereof - Google Patents

Aminocyclohexyl ether compounds and uses thereof

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Publication number
BE2011C002I2
BE2011C002I2 BE2011C002C BE2011C002C BE2011C002I2 BE 2011C002 I2 BE2011C002 I2 BE 2011C002I2 BE 2011C002 C BE2011C002 C BE 2011C002C BE 2011C002 C BE2011C002 C BE 2011C002C BE 2011C002 I2 BE2011C002 I2 BE 2011C002I2
Authority
BE
Belgium
Prior art keywords
ether compounds
compounds
aminocyclohexyl ether
compositions
formula
Prior art date
Application number
BE2011C002C
Other languages
French (fr)
Original Assignee
Cardiome Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiome Pharma Corp filed Critical Cardiome Pharma Corp
Publication of BE2011C002I2 publication Critical patent/BE2011C002I2/en

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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
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Abstract

Aminocyclohexyl ether compounds of formula (I), or a solvate or pharmaceutically acceptable salt thereof: <CHEM> are disclosed. In said formula, A, X and R, -R5 have the meanings given in the description. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
BE2011C002C 1998-04-01 2011-01-20 Aminocyclohexyl ether compounds and uses thereof BE2011C002I2 (en)

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ID27178A (en) 2001-03-08
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BRPI9909282B1 (en) 2011-07-26
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US20050192208A2 (en) 2005-09-01
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