AU752265B2 - Stabilized pharmaceutical composition in lyophilized form - Google Patents

Stabilized pharmaceutical composition in lyophilized form Download PDF

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Publication number
AU752265B2
AU752265B2 AU55722/00A AU5572200A AU752265B2 AU 752265 B2 AU752265 B2 AU 752265B2 AU 55722/00 A AU55722/00 A AU 55722/00A AU 5572200 A AU5572200 A AU 5572200A AU 752265 B2 AU752265 B2 AU 752265B2
Authority
AU
Australia
Prior art keywords
composition
compound
pharmaceutical composition
stabilizer
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired, expires
Application number
AU55722/00A
Other languages
English (en)
Other versions
AU5572200A (en
Inventor
Akihiro Kasai
Kazumi Otomo
Seiji Sawai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16210881&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU752265(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of AU5572200A publication Critical patent/AU5572200A/en
Application granted granted Critical
Publication of AU752265B2 publication Critical patent/AU752265B2/en
Assigned to ASTELLAS PHARMA INC. reassignment ASTELLAS PHARMA INC. Alteration of Name(s) in Register under S187 Assignors: FUJISAWA PHARMACEUTICAL CO., LTD.
Assigned to SANDOZ AG reassignment SANDOZ AG Request for Assignment Assignors: ASTELLAS PHARMA INC.
Adjusted expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU55722/00A 1999-07-01 2000-06-29 Stabilized pharmaceutical composition in lyophilized form Expired AU752265B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP18771399 1999-07-01
JP11/187713 1999-07-01
PCT/JP2000/004381 WO2001002002A1 (en) 1999-07-01 2000-06-29 Stabilized pharmaceutical composition in lyophilized form

Publications (2)

Publication Number Publication Date
AU5572200A AU5572200A (en) 2001-01-22
AU752265B2 true AU752265B2 (en) 2002-09-12

Family

ID=16210881

Family Applications (1)

Application Number Title Priority Date Filing Date
AU55722/00A Expired AU752265B2 (en) 1999-07-01 2000-06-29 Stabilized pharmaceutical composition in lyophilized form

Country Status (28)

Country Link
US (2) US6774104B1 (enExample)
EP (1) EP1107777B1 (enExample)
JP (2) JP3381722B2 (enExample)
KR (1) KR100454784B1 (enExample)
CN (2) CN100352495C (enExample)
AR (1) AR024634A1 (enExample)
AT (1) ATE280583T1 (enExample)
AU (1) AU752265B2 (enExample)
BR (2) BRPI0006823B8 (enExample)
CA (1) CA2341568C (enExample)
CZ (1) CZ295720B6 (enExample)
DE (1) DE60015279T2 (enExample)
ES (1) ES2225161T3 (enExample)
HK (1) HK1040057B (enExample)
HU (1) HU229089B1 (enExample)
ID (1) ID29468A (enExample)
IL (2) IL141455A0 (enExample)
MX (1) MXPA01000601A (enExample)
NO (1) NO330353B1 (enExample)
NZ (1) NZ510290A (enExample)
OA (1) OA11601A (enExample)
PL (1) PL200141B1 (enExample)
PT (1) PT1107777E (enExample)
RU (1) RU2251411C2 (enExample)
TR (1) TR200100609T1 (enExample)
TW (1) TWI233805B (enExample)
WO (1) WO2001002002A1 (enExample)
ZA (1) ZA200101589B (enExample)

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TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
ITMI20021040A1 (it) * 2002-05-16 2003-11-17 Novuspharma Spa Composizioni farmaceutiche iniettabili di un derivato antracenedionico ad attivita' antitumorale
EP1525884B1 (en) 2002-07-31 2011-10-12 Senju Pharmaceutical Co., Ltd. Aqueous liquid preparations and light-stabilized aqueous liquid preparations
US8877168B1 (en) 2002-07-31 2014-11-04 Senju Pharmaceuticals Co., Ltd. Aqueous liquid preparations and light-stabilized aqueous liquid preparations
US7119061B2 (en) * 2002-11-18 2006-10-10 Vicuron Pharmaceuticals, Inc. Dalbavancin compositions for treatment of bacterial infections
AU2003298662A1 (en) * 2002-11-18 2004-06-15 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
CA2558191C (en) * 2004-03-04 2011-01-04 Eisai R&D Management Co., Ltd. Composition containing benzamidine derivative and method for stabilizing benzamidine derivative
US7514450B2 (en) * 2004-05-19 2009-04-07 Neurosearch A/S Azabicyclic aryl derivatives
EP2417986A1 (en) * 2004-11-22 2012-02-15 Anadis Ltd. Bioactive compositions
KR101307999B1 (ko) 2004-12-01 2013-09-12 니폰 조키 세야쿠 가부시키가이샤 건조물 및 그 제조방법
KR20080028942A (ko) * 2005-07-20 2008-04-02 교와 메덱스 가부시키가이샤 생체 시료 중의 펩티드의 안정화 방법
CN1962852B (zh) * 2006-11-27 2011-11-09 西北农林科技大学 红景天多糖在制备抗冻剂中的新用途及其产品和制备方法
CN102614491B (zh) * 2011-01-31 2014-04-16 上海天伟生物制药有限公司 一种含有棘白菌素类抗真菌剂米卡芬净的药用组合物及其制备方法和用途
CN102614492B (zh) * 2011-01-31 2013-12-11 上海天伟生物制药有限公司 一种含有棘白菌素类抗真菌剂米卡芬净的液体药用组合物
CN104968348B (zh) * 2012-05-22 2018-04-17 Paion英国有限公司 包含短效苯二氮杂*类化合物的组合物
US20140274994A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Stabilizing ceftolozane
US20140274993A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane-tazobactam pharmaceutical compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
CN103330933B (zh) * 2013-04-26 2015-08-05 江苏豪森药业股份有限公司 含有米卡芬净或其盐的药物组合物
CN103330932B (zh) * 2013-04-26 2015-12-23 江苏豪森药业股份有限公司 一种米卡芬净或其盐的药物组合物
ES2978920T3 (es) * 2013-06-05 2024-09-23 Univ British Columbia Compuestos antifibrogénicos, métodos y usos de los mismos
US10376496B2 (en) 2013-09-09 2019-08-13 Merck, Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane
KR101611349B1 (ko) 2014-04-14 2016-04-12 신우철 안정성이 개선된 밀크씨슬 엑스의 제형
JP7109189B2 (ja) * 2014-05-29 2022-07-29 シャンハイ テックウェル バイオファーマシューティカル カンパニー リミテッド シクロペプチド系化合物の組成物およびその製造方法と使用
RU2732129C2 (ru) * 2014-12-05 2020-09-11 Мейдзи Сейка Фарма Ко., Лтд. Способ производства кристаллов производного диазабициклооктана и стабильного лиофилизированного препарата
DK3240529T3 (da) * 2014-12-31 2022-02-28 Galenicum Health S L U Stabile farmaceutiske sammensætninger omfattende micafungin
PL3058958T3 (pl) 2015-02-23 2019-02-28 Selectchemie Ag Kompozycja anidulafunginy
AU2017376960B2 (en) 2016-12-16 2023-12-14 Baxter Healthcare Sa Micafungin compositions
US11185527B2 (en) 2017-06-26 2021-11-30 Wayne State University Methods and compositions relating to steroid hormone receptor-dependent cancers
RU2666148C1 (ru) * 2017-10-05 2018-09-06 Общество с ограниченной ответственностью "Новые Антибиотики" Способ получения водорастворимой лиофилизированной формы соли бис(2-тио-4,6-диоксо-1,2,3,4,5,6-гексагидропиримидин-5-ил)-(4-нитрофенил)метана
EP3485873A1 (en) 2017-11-17 2019-05-22 Cadila Healthcare Limited Stable pharmaceutical injectable compositions of micafungin

Citations (3)

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Publication number Priority date Publication date Assignee Title
WO1997039763A1 (en) * 1996-04-19 1997-10-30 Merck & Co., Inc. Compositions comprising antifungal agent and acetate buffer
WO2000051564A1 (en) * 1999-03-03 2000-09-08 Eli Lilly And Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
WO2000051567A1 (en) * 1999-03-03 2000-09-08 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions

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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997039763A1 (en) * 1996-04-19 1997-10-30 Merck & Co., Inc. Compositions comprising antifungal agent and acetate buffer
WO2000051564A1 (en) * 1999-03-03 2000-09-08 Eli Lilly And Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
WO2000051567A1 (en) * 1999-03-03 2000-09-08 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions

Also Published As

Publication number Publication date
CN1179748C (zh) 2004-12-15
AR024634A1 (es) 2002-10-16
CN1315865A (zh) 2001-10-03
JP2002363097A (ja) 2002-12-18
HK1040057A1 (en) 2002-05-24
CN1636591A (zh) 2005-07-13
KR20010072903A (ko) 2001-07-31
ATE280583T1 (de) 2004-11-15
AU5572200A (en) 2001-01-22
US7112565B2 (en) 2006-09-26
KR100454784B1 (ko) 2004-11-05
HUP0103740A2 (hu) 2002-02-28
ES2225161T3 (es) 2005-03-16
DE60015279D1 (de) 2004-12-02
HUP0103740A3 (en) 2002-08-28
ID29468A (id) 2001-08-30
PT1107777E (pt) 2005-01-31
HK1080724A1 (zh) 2006-05-04
JP4691866B2 (ja) 2011-06-01
ZA200101589B (en) 2002-09-02
WO2001002002A1 (en) 2001-01-11
MXPA01000601A (es) 2002-04-08
CZ20011186A3 (cs) 2001-09-12
NO20010893L (no) 2001-04-24
OA11601A (en) 2004-07-30
NO20010893D0 (no) 2001-02-22
DE60015279T2 (de) 2005-05-25
CA2341568A1 (en) 2001-01-11
NO330353B1 (no) 2011-04-04
PL200141B1 (pl) 2008-12-31
EP1107777A1 (en) 2001-06-20
NZ510290A (en) 2003-07-25
US20040157769A1 (en) 2004-08-12
RU2251411C2 (ru) 2005-05-10
JP3381722B2 (ja) 2003-03-04
BRPI0006823B1 (pt) 2020-01-07
HK1040057B (zh) 2005-08-05
PL346297A1 (en) 2002-01-28
US6774104B1 (en) 2004-08-10
JP2003503462A (ja) 2003-01-28
IL141455A (en) 2006-12-31
BRPI0006823B8 (pt) 2021-05-25
IL141455A0 (en) 2002-03-10
TWI233805B (en) 2005-06-11
HU229089B1 (en) 2013-07-29
CZ295720B6 (cs) 2005-10-12
CA2341568C (en) 2011-10-25
EP1107777B1 (en) 2004-10-27
BR0006823A (pt) 2001-06-05
CN100352495C (zh) 2007-12-05
TR200100609T1 (tr) 2001-07-23

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