HK1040057B - 冻干形式的稳定的药用组合物 - Google Patents

冻干形式的稳定的药用组合物 Download PDF

Info

Publication number
HK1040057B
HK1040057B HK02101689.2A HK02101689A HK1040057B HK 1040057 B HK1040057 B HK 1040057B HK 02101689 A HK02101689 A HK 02101689A HK 1040057 B HK1040057 B HK 1040057B
Authority
HK
Hong Kong
Prior art keywords
group
substituted
compound
pharmaceutical composition
phenyl
Prior art date
Application number
HK02101689.2A
Other languages
English (en)
Chinese (zh)
Other versions
HK1040057A1 (en
Inventor
泽居清治
澤居清治
笠井昭宏
大友和三
Original Assignee
安斯泰来制药有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16210881&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1040057(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 安斯泰来制药有限公司 filed Critical 安斯泰来制药有限公司
Publication of HK1040057A1 publication Critical patent/HK1040057A1/xx
Publication of HK1040057B publication Critical patent/HK1040057B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
HK02101689.2A 1999-07-01 2000-06-29 冻干形式的稳定的药用组合物 HK1040057B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP187713/1999 1999-07-01
JP18771399 1999-07-01
PCT/JP2000/004381 WO2001002002A1 (en) 1999-07-01 2000-06-29 Stabilized pharmaceutical composition in lyophilized form

Publications (2)

Publication Number Publication Date
HK1040057A1 HK1040057A1 (en) 2002-05-24
HK1040057B true HK1040057B (zh) 2005-08-05

Family

ID=16210881

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02101689.2A HK1040057B (zh) 1999-07-01 2000-06-29 冻干形式的稳定的药用组合物

Country Status (28)

Country Link
US (2) US6774104B1 (enExample)
EP (1) EP1107777B1 (enExample)
JP (2) JP3381722B2 (enExample)
KR (1) KR100454784B1 (enExample)
CN (2) CN100352495C (enExample)
AR (1) AR024634A1 (enExample)
AT (1) ATE280583T1 (enExample)
AU (1) AU752265B2 (enExample)
BR (2) BRPI0006823B8 (enExample)
CA (1) CA2341568C (enExample)
CZ (1) CZ295720B6 (enExample)
DE (1) DE60015279T2 (enExample)
ES (1) ES2225161T3 (enExample)
HK (1) HK1040057B (enExample)
HU (1) HU229089B1 (enExample)
ID (1) ID29468A (enExample)
IL (2) IL141455A0 (enExample)
MX (1) MXPA01000601A (enExample)
NO (1) NO330353B1 (enExample)
NZ (1) NZ510290A (enExample)
OA (1) OA11601A (enExample)
PL (1) PL200141B1 (enExample)
PT (1) PT1107777E (enExample)
RU (1) RU2251411C2 (enExample)
TR (1) TR200100609T1 (enExample)
TW (1) TWI233805B (enExample)
WO (1) WO2001002002A1 (enExample)
ZA (1) ZA200101589B (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
ITMI20021040A1 (it) * 2002-05-16 2003-11-17 Novuspharma Spa Composizioni farmaceutiche iniettabili di un derivato antracenedionico ad attivita' antitumorale
AU2003252746A1 (en) 2002-07-31 2004-02-16 Senju Pharmaceutical Co., Ltd. Aqueous liquid preparations and light-stabilized aqueous liquid preparations
US8877168B1 (en) 2002-07-31 2014-11-04 Senju Pharmaceuticals Co., Ltd. Aqueous liquid preparations and light-stabilized aqueous liquid preparations
EP1565201B1 (en) * 2002-11-18 2018-10-31 Vicuron Pharmaceuticals, Inc. Methods of administering dalbavancin for treatment of bacterial infections
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
US7119061B2 (en) * 2002-11-18 2006-10-10 Vicuron Pharmaceuticals, Inc. Dalbavancin compositions for treatment of bacterial infections
JPWO2005084679A1 (ja) * 2004-03-04 2007-11-29 エーザイ・アール・アンド・ディー・マネジメント株式会社 ベンズアミジン誘導体含有組成物及びベンズアミジン誘導体の安定化方法
WO2005111033A2 (en) * 2004-05-19 2005-11-24 Neurosearch A/S Novel azabicyclic aryl derivatives
KR20070109985A (ko) * 2004-11-22 2007-11-15 아나디스 리미티드 생물활성 조성물
KR101307999B1 (ko) 2004-12-01 2013-09-12 니폰 조키 세야쿠 가부시키가이샤 건조물 및 그 제조방법
US8173385B2 (en) * 2005-07-20 2012-05-08 Kyowa Medex Co., Ltd. Method for stabilization of peptides in a biological sample
CN1962852B (zh) * 2006-11-27 2011-11-09 西北农林科技大学 红景天多糖在制备抗冻剂中的新用途及其产品和制备方法
CN102614492B (zh) * 2011-01-31 2013-12-11 上海天伟生物制药有限公司 一种含有棘白菌素类抗真菌剂米卡芬净的液体药用组合物
CN102614491B (zh) * 2011-01-31 2014-04-16 上海天伟生物制药有限公司 一种含有棘白菌素类抗真菌剂米卡芬净的药用组合物及其制备方法和用途
BR112014029108B1 (pt) * 2012-05-22 2022-02-08 Paion Uk Limited Composições que compreendem benzodiazepinas de curta ação, uso de uma mistura de pelo menos um dissacarídeo e pelo menos uma dextrana e método de preparação de uma composição farmacêutica
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US9320740B2 (en) 2013-03-15 2016-04-26 Merck Sharp & Dohme Corp. Ceftolozane-tazobactam pharmaceutical compositions
PL2893929T3 (pl) 2013-03-15 2025-07-21 Merck Sharp & Dohme Llc Kompozycje antybiotykowe ceftolozanu
CN103330933B (zh) * 2013-04-26 2015-08-05 江苏豪森药业股份有限公司 含有米卡芬净或其盐的药物组合物
CN103330932B (zh) * 2013-04-26 2015-12-23 江苏豪森药业股份有限公司 一种米卡芬净或其盐的药物组合物
JP6473938B2 (ja) * 2013-06-05 2019-02-27 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア 抗線維化化合物、その方法および使用
EP3043797B1 (en) 2013-09-09 2020-04-08 Merck Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane
KR101611349B1 (ko) 2014-04-14 2016-04-12 신우철 안정성이 개선된 밀크씨슬 엑스의 제형
US20170190742A1 (en) * 2014-05-29 2017-07-06 Shanghai Techwell Biopharmaceutical Co., Ltd. Composition of cyclic peptide compound, preparation method for same, and uses thereof
TWI691499B (zh) * 2014-12-05 2020-04-21 日商明治製菓藥業股份有限公司 二氮雜雙環辛烷衍生物之結晶及安定的凍結乾燥製劑的製造法
DK3240529T3 (da) * 2014-12-31 2022-02-28 Galenicum Health S L U Stabile farmaceutiske sammensætninger omfattende micafungin
PL3058958T3 (pl) 2015-02-23 2019-02-28 Selectchemie Ag Kompozycja anidulafunginy
DK3554474T3 (da) 2016-12-16 2024-02-19 Baxter Int Micafungin-sammensætninger
WO2019005829A1 (en) * 2017-06-26 2019-01-03 Wayne State University METHODS AND COMPOSITIONS RELATING TO CANCER DEPENDENT ON HORMONE RECEPTORS
RU2666148C1 (ru) * 2017-10-05 2018-09-06 Общество с ограниченной ответственностью "Новые Антибиотики" Способ получения водорастворимой лиофилизированной формы соли бис(2-тио-4,6-диоксо-1,2,3,4,5,6-гексагидропиримидин-5-ил)-(4-нитрофенил)метана
EP3485873A1 (en) 2017-11-17 2019-05-22 Cadila Healthcare Limited Stable pharmaceutical injectable compositions of micafungin

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03193735A (ja) 1989-12-22 1991-08-23 Shionogi & Co Ltd グリコペプチド系抗生物質の安定化組成物
JPH03240727A (ja) 1990-02-15 1991-10-28 Toyo Jozo Co Ltd ニューモシスチス・カリニ肺炎治療剤
IL98506A (en) * 1990-06-18 1996-09-12 Fujisawa Pharmaceutical Co Cyclic peptide antibiotics processes for the preparation thereof and pharmaceutical compositions containing them
JP3193735B2 (ja) 1991-07-24 2001-07-30 株式会社リコー カラー画像形成装置の搬送装置
RU2095081C1 (ru) * 1991-12-13 1997-11-10 Акционерное общество "Биофа" Фармацевтическая композиция антивирусного действия
JPH0651641A (ja) 1992-07-30 1994-02-25 Olympus Optical Co Ltd 湿式現像装置
JPH06172204A (ja) * 1992-12-09 1994-06-21 Asahi Chem Ind Co Ltd アクレアシン類含有リポソーム製剤およびその製造法
JP3240727B2 (ja) 1993-02-25 2001-12-25 ソニー株式会社 偏平型陰極線管の画像歪補正装置
US6268338B1 (en) * 1993-04-30 2001-07-31 Merck & Co., Inc. Cyclohexapeptidyl amine compounds
AU681119B2 (en) * 1993-05-17 1997-08-21 Fujisawa Pharmaceutical Co., Ltd. New polypeptide compound and a process for preparation thereof
JP2897427B2 (ja) * 1994-10-07 1999-05-31 藤沢薬品工業株式会社 抗微生物活性を有する環状ヘキサペプチド化合物
GB9512854D0 (en) * 1995-06-23 1995-08-23 Wellcome Found Novel formulation
US6245349B1 (en) * 1996-02-23 2001-06-12 éLAN CORPORATION PLC Drug delivery compositions suitable for intravenous injection
CA2248348C (en) * 1996-03-08 2008-06-10 Fujisawa Pharmaceutical Co., Ltd. Process for the deacylation of cyclic lipopeptides
PE63998A1 (es) * 1996-04-19 1998-10-30 Merck & Co Inc Composiciones anti-fungosas
JPH09301997A (ja) 1996-05-17 1997-11-25 Yamanouchi Pharmaceut Co Ltd 新規環状ペプチド系化合物
FR2755857B1 (fr) * 1996-11-19 1998-12-24 Rhone Poulenc Rorer Sa Compositions pharmaceutiques stabilisees, a base de quinupristine et de dalfopristine et leur preparation
AUPO371596A0 (en) * 1996-11-19 1996-12-12 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPO381496A0 (en) * 1996-11-25 1996-12-19 Fujisawa Pharmaceutical Co., Ltd. New compound
JPH10279498A (ja) * 1997-04-07 1998-10-20 Nippon Shinyaku Co Ltd 慢性関節リウマチ治療剤
JP3544847B2 (ja) * 1998-01-16 2004-07-21 三菱電機株式会社 光学的情報再生方法および装置
CN100335122C (zh) * 1999-03-03 2007-09-05 伊莱利利公司 含有成胶束表面活性剂的棘白菌素药物制剂
WO2000051567A1 (en) * 1999-03-03 2000-09-08 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent

Also Published As

Publication number Publication date
TR200100609T1 (tr) 2001-07-23
US7112565B2 (en) 2006-09-26
HUP0103740A3 (en) 2002-08-28
MXPA01000601A (es) 2002-04-08
BRPI0006823B8 (pt) 2021-05-25
OA11601A (en) 2004-07-30
JP2002363097A (ja) 2002-12-18
AU752265B2 (en) 2002-09-12
KR20010072903A (ko) 2001-07-31
CA2341568C (en) 2011-10-25
US20040157769A1 (en) 2004-08-12
BRPI0006823B1 (pt) 2020-01-07
CN100352495C (zh) 2007-12-05
IL141455A (en) 2006-12-31
HUP0103740A2 (hu) 2002-02-28
KR100454784B1 (ko) 2004-11-05
HK1080724A1 (zh) 2006-05-04
JP4691866B2 (ja) 2011-06-01
PL200141B1 (pl) 2008-12-31
CA2341568A1 (en) 2001-01-11
EP1107777B1 (en) 2004-10-27
US6774104B1 (en) 2004-08-10
CZ295720B6 (cs) 2005-10-12
EP1107777A1 (en) 2001-06-20
NO330353B1 (no) 2011-04-04
HK1040057A1 (en) 2002-05-24
NO20010893L (no) 2001-04-24
NZ510290A (en) 2003-07-25
ATE280583T1 (de) 2004-11-15
BR0006823A (pt) 2001-06-05
DE60015279T2 (de) 2005-05-25
NO20010893D0 (no) 2001-02-22
AU5572200A (en) 2001-01-22
ES2225161T3 (es) 2005-03-16
JP2003503462A (ja) 2003-01-28
IL141455A0 (en) 2002-03-10
CZ20011186A3 (cs) 2001-09-12
JP3381722B2 (ja) 2003-03-04
HU229089B1 (en) 2013-07-29
CN1636591A (zh) 2005-07-13
PT1107777E (pt) 2005-01-31
RU2251411C2 (ru) 2005-05-10
ZA200101589B (en) 2002-09-02
AR024634A1 (es) 2002-10-16
TWI233805B (en) 2005-06-11
ID29468A (id) 2001-08-30
PL346297A1 (en) 2002-01-28
DE60015279D1 (de) 2004-12-02
WO2001002002A1 (en) 2001-01-11
CN1179748C (zh) 2004-12-15
CN1315865A (zh) 2001-10-03

Similar Documents

Publication Publication Date Title
HK1040057B (zh) 冻干形式的稳定的药用组合物
CN1147472C (zh) 具有组蛋白脱乙酰酶抑制剂活性的苯甲酰胺制剂
CN1871014A (zh) 含有前列腺素的药物组合物
CN1010279B (zh) 含有斯波胍灵活性成分的注射用药物组合物的制备方法
CN1646172A (zh) 包含喜树碱衍生物的液体制剂以及冻干该制剂制得的药物组合物
CN1792362A (zh) 阿比朵尔及其盐的静脉给药制剂及制备方法
US20040023858A1 (en) Antifungal combination therapy
CN1183908C (zh) 一种尼莫地平的注射用药物组合物及其制备方法
HK1080724B (en) Stabilized pharmaceutical composition in lyophilized form
CN1820748A (zh) 一种左旋奥硝唑冻干粉针注射剂
CN1283245C (zh) 硝酸异山梨酯的冻干粉针及其制备方法
WO2002053584A1 (en) Stabilized pharmaceutical composition in lyophilized form
HK1022832A1 (en) Stabilised pharmaceutical compositions, with quinupristine and dalfopristine base and their preparation
HK1022832B (en) Stabilised pharmaceutical compositions, with quinupristine and dalfopristine base and their preparation
AU1663401A (en) New use
HK1057478A (en) Ophthalmic solution

Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20200628