AU2016315924B2 - Detecting gastric neoplasm - Google Patents

Detecting gastric neoplasm Download PDF

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Publication number
AU2016315924B2
AU2016315924B2 AU2016315924A AU2016315924A AU2016315924B2 AU 2016315924 B2 AU2016315924 B2 AU 2016315924B2 AU 2016315924 A AU2016315924 A AU 2016315924A AU 2016315924 A AU2016315924 A AU 2016315924A AU 2016315924 B2 AU2016315924 B2 AU 2016315924B2
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Australia
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methylation
dna
seq
sample
nos
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AU2016315924A1 (en
Inventor
David A. Ahlquist
Hatim T. Allawi
John B. Kisiel
Douglas W. Mahoney
William R. Taylor
Tracy C. Yab
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Exact Sciences Corp
Mayo Clinic in Florida
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Mayo Foundation for Medical Education and Research
Exact Sciences Corp
Mayo Clinic in Florida
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Assigned to MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, EXACT SCIENCES CORPORATION reassignment MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH Request for Assignment Assignors: EXACT SCIENCES DEVELOPMENT COMPANY, LLC, MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AU2016315924A 2015-08-31 2016-08-31 Detecting gastric neoplasm Active AU2016315924B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2022275451A AU2022275451B2 (en) 2015-08-31 2022-11-23 Detecting gastric neoplasm

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562212221P 2015-08-31 2015-08-31
US62/212,221 2015-08-31
PCT/US2016/049653 WO2017040627A1 (en) 2015-08-31 2016-08-31 Detecting gastric neoplasm

Related Child Applications (1)

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AU2022275451A Division AU2022275451B2 (en) 2015-08-31 2022-11-23 Detecting gastric neoplasm

Publications (2)

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AU2016315924A1 AU2016315924A1 (en) 2018-02-08
AU2016315924B2 true AU2016315924B2 (en) 2022-08-25

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AU2016315924A Active AU2016315924B2 (en) 2015-08-31 2016-08-31 Detecting gastric neoplasm
AU2022275451A Active AU2022275451B2 (en) 2015-08-31 2022-11-23 Detecting gastric neoplasm

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US (4) US10006093B2 (enExample)
EP (1) EP3344784A4 (enExample)
JP (4) JP6871926B2 (enExample)
KR (3) KR20250172724A (enExample)
CN (2) CN108138235B (enExample)
AU (2) AU2016315924B2 (enExample)
CA (1) CA2992790A1 (enExample)
WO (1) WO2017040627A1 (enExample)

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US10184154B2 (en) 2014-09-26 2019-01-22 Mayo Foundation For Medical Education And Research Detecting cholangiocarcinoma
WO2016160454A1 (en) 2015-03-27 2016-10-06 Exact Sciences Corporation Detecting esophageal disorders
KR20250172724A (ko) 2015-08-31 2025-12-09 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 위 신생물 검출 방법
KR20250073555A (ko) 2015-10-30 2025-05-27 이그잭트 사이언시즈 코포레이션 복합 증폭 검출 분석 및 혈장으로부터 dna의 분리 및 검출 방법
EP3436604A1 (en) * 2016-04-01 2019-02-06 NanoMed Diagnostics B.V. Detection of cancer in urine
US10370726B2 (en) * 2016-04-14 2019-08-06 Mayo Foundation For Medical Education And Research Detecting colorectal neoplasia
CN116064796A (zh) 2016-05-05 2023-05-05 精密科学公司 通过分析甲基化dna来检测肺肿瘤
JP7289264B2 (ja) 2017-01-27 2023-06-09 エグザクト サイエンシーズ コーポレーション メチル化ｄｎａの分析による結腸腫瘍の検出
JP7277460B2 (ja) 2017-11-30 2023-05-19 マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ 乳癌の検出
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US20220162709A1 (en) * 2019-04-03 2022-05-26 Mayo Foundation For Medical Education And Research Detecting pancreatic ductal adenocarcinoma in plasma
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JP7646577B2 (ja) * 2019-06-21 2025-03-17 ユニヴェルシテ・パリ・シテ 胃癌を診断するための高メチル化遺伝子の検出
CN110423814A (zh) * 2019-07-19 2019-11-08 江苏元丞生物科技有限公司 Elmo1基因甲基化检测试剂盒及其应用
US11702704B2 (en) 2019-10-31 2023-07-18 Mayo Foundation For Medical Education And Research Detecting ovarian cancer
US11898199B2 (en) 2019-11-11 2024-02-13 Universal Diagnostics, S.A. Detection of colorectal cancer and/or advanced adenomas
CN111549129B (zh) * 2020-03-30 2023-08-29 宁波美康盛德医学检验所有限公司 用于检测胃癌的试剂盒及其应用
US20220071605A1 (en) * 2020-04-17 2022-03-10 Exact Sciences Development Company, Llc Sampling device and analysis of methylated dna
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KR20230150814A (ko) * 2021-01-29 2023-10-31 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 다양한 유형의 암에 대한 존재 또는 부재의 검출
CN115433778B (zh) * 2021-06-02 2023-06-16 武汉艾米森生命科技有限公司 一种用于检测结直肠癌或结直肠腺瘤相关基因甲基化的检测试剂、试剂盒及其应用
CN113308544B (zh) * 2021-06-04 2022-07-05 武汉艾米森生命科技有限公司 用于dna甲基化检测的试剂及食管癌检测试剂盒
CN118272525A (zh) * 2021-11-24 2024-07-02 博尔诚（北京）科技有限公司 用于胃癌筛查的标志物、探针组合物及其应用
CN117344010B (zh) * 2022-06-29 2024-04-26 广州市基准医疗有限责任公司 用于诊断胃癌的dna甲基化生物标记物、试剂盒及用途
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CN117126942B (zh) * 2023-10-05 2026-01-06 上海奕谱生物科技有限公司 可用于肿瘤鉴定的新型DNA甲基化标志物TAGMe-3及其用途

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