AU2010202640B2 - Sustained drug-releasing stent - Google Patents

Sustained drug-releasing stent Download PDF

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Publication number
AU2010202640B2
AU2010202640B2 AU2010202640A AU2010202640A AU2010202640B2 AU 2010202640 B2 AU2010202640 B2 AU 2010202640B2 AU 2010202640 A AU2010202640 A AU 2010202640A AU 2010202640 A AU2010202640 A AU 2010202640A AU 2010202640 B2 AU2010202640 B2 AU 2010202640B2
Authority
AU
Australia
Prior art keywords
stent
argatroban
coated layer
drug
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2010202640A
Other languages
English (en)
Other versions
AU2010202640A1 (en
Inventor
Hiroo Iwata
Zhen Yu Jin
Akira Mochizuki
Ikuo Omura
Shuzo Yamashita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Stent Technology Co Ltd
Tokai University Educational System
Original Assignee
Japan Stent Technology Co Ltd
Tokai University Educational System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2008294278A external-priority patent/AU2008294278C1/en
Application filed by Japan Stent Technology Co Ltd, Tokai University Educational System filed Critical Japan Stent Technology Co Ltd
Priority to AU2010202640A priority Critical patent/AU2010202640B2/en
Publication of AU2010202640A1 publication Critical patent/AU2010202640A1/en
Assigned to JAPAN STENT TECHNOLOGY CO., LTD., IWATA, HIROO, TOKAI UNIVERSITY EDUCATIONAL SYSTEM reassignment JAPAN STENT TECHNOLOGY CO., LTD. Request for Assignment Assignors: IWATA, HIROO, JAPAN STENT TECHNOLOGY CO., LTD., TOKAI UNIVERSITY EDUCATIONAL SYSTEM, TOYO ADVANCED TECHNOLOGIES CO., LTD.
Application granted granted Critical
Publication of AU2010202640B2 publication Critical patent/AU2010202640B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
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    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
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    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
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    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A61F2002/91541—Adjacent bands are arranged out of phase
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61L33/0005—Use of materials characterised by their function or physical properties
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    • A61L33/0041—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate characterised by the choice of an antithrombatic agent other than heparin

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
AU2010202640A 2007-09-04 2010-06-24 Sustained drug-releasing stent Ceased AU2010202640B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2010202640A AU2010202640B2 (en) 2007-09-04 2010-06-24 Sustained drug-releasing stent

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2007-228788 2007-09-04
JP2007228788 2007-09-04
AU2008294278A AU2008294278C1 (en) 2007-09-04 2008-09-03 Stent for controlled drug release
PCT/JP2008/002410 WO2009031295A1 (ja) 2007-09-04 2008-09-03 薬剤徐放性ステント
AU2010202640A AU2010202640B2 (en) 2007-09-04 2010-06-24 Sustained drug-releasing stent

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU2008294278A Division AU2008294278C1 (en) 2007-09-04 2008-09-03 Stent for controlled drug release

Publications (2)

Publication Number Publication Date
AU2010202640A1 AU2010202640A1 (en) 2010-07-15
AU2010202640B2 true AU2010202640B2 (en) 2013-01-10

Family

ID=40428619

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010202640A Ceased AU2010202640B2 (en) 2007-09-04 2010-06-24 Sustained drug-releasing stent

Country Status (7)

Country Link
US (5) US8409272B2 (enExample)
EP (2) EP2201966A4 (enExample)
JP (4) JP5368991B2 (enExample)
KR (2) KR20100085179A (enExample)
CN (2) CN101940802B (enExample)
AU (1) AU2010202640B2 (enExample)
WO (1) WO2009031295A1 (enExample)

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JP5487122B2 (ja) 2009-02-06 2014-05-07 学校法人慶應義塾 生体の管状器官に使用するステント
WO2010101072A1 (ja) 2009-03-02 2010-09-10 株式会社日本ステントテクノロジー 薬剤溶出性ステント
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US9265633B2 (en) 2009-05-20 2016-02-23 480 Biomedical, Inc. Drug-eluting medical implants
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US10166128B2 (en) * 2011-01-14 2019-01-01 W. L. Gore & Associates. Inc. Lattice
CN110075355A (zh) * 2013-10-22 2019-08-02 康斯瓦维有限责任公司 用于抑制支架型心瓣膜或生物假体的狭窄、阻塞或钙化的方法
JP2015154921A (ja) * 2014-01-17 2015-08-27 株式会社日本ステントテクノロジー 薬剤徐放性ステント
JP5695259B1 (ja) 2014-02-19 2015-04-01 株式会社World Medish 高柔軟性ステント
US10143779B2 (en) * 2014-05-16 2018-12-04 Terumo Kabushiki Kaisha Method of inhibiting thickening of vascular intima
JP2016005533A (ja) * 2014-05-30 2016-01-14 株式会社日本ステントテクノロジー ステント
TWI721956B (zh) 2014-10-28 2021-03-21 日商Jimro股份有限公司 藥劑溶出型支架
JP2016163619A (ja) * 2015-03-06 2016-09-08 株式会社日本ステントテクノロジー 防食効果を利用したマグネシウムの分解速度制御
JP2016165375A (ja) * 2015-03-10 2016-09-15 株式会社日本ステントテクノロジー 防食被覆層を有するステントの製造方法
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WO2016163339A1 (ja) * 2015-04-07 2016-10-13 二プロ株式会社 ステント
JP6558569B2 (ja) * 2015-05-21 2019-08-14 ニプロ株式会社 ステント
WO2017090747A1 (ja) * 2015-11-26 2017-06-01 株式会社日本医療機器技研 生体吸収性ステント
WO2017143302A1 (en) * 2016-02-17 2017-08-24 Brigham Young University Multi-stage stent devices and associated methods
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CN110665072A (zh) * 2019-11-23 2020-01-10 吉林省蔚来生物科技有限公司 一种靶向药物释放介入类医疗器械及其制备方法
US11654036B2 (en) * 2020-05-26 2023-05-23 Elixir Medical Corporation Anticoagulant compounds and methods and devices for their use
WO2021242783A1 (en) * 2020-05-26 2021-12-02 Elixir Medical Corporation Anticoagulant compounds and methods and devices for their use
WO2022034905A1 (ja) 2020-08-12 2022-02-17 康宏 正林 ステント
CN114159197B (zh) * 2022-02-14 2022-05-17 北京美中双和医疗器械股份有限公司 一种可降解生物医用镁合金药物洗脱血管支架及制备方法
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