AU2004226207A1 - 4-substituted quinolein derivatives with antimicrobial activity - Google Patents

4-substituted quinolein derivatives with antimicrobial activity Download PDF

Info

Publication number
AU2004226207A1
AU2004226207A1 AU2004226207A AU2004226207A AU2004226207A1 AU 2004226207 A1 AU2004226207 A1 AU 2004226207A1 AU 2004226207 A AU2004226207 A AU 2004226207A AU 2004226207 A AU2004226207 A AU 2004226207A AU 2004226207 A1 AU2004226207 A1 AU 2004226207A1
Authority
AU
Australia
Prior art keywords
methoxyquinolin
fluoro
propyl
general formula
difluorophenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2004226207A
Other languages
English (en)
Inventor
Antony Bigot
Michel Cheve
Youssef El Ahmad
Jean-Luc Malleron
Jean-Paul Martin
Serge Mignani
Guy Pantel
Baptiste Ronan
Michel Tabart
Fabrice Viviani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of AU2004226207A1 publication Critical patent/AU2004226207A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2004226207A 2003-03-28 2004-03-29 4-substituted quinolein derivatives with antimicrobial activity Abandoned AU2004226207A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0303812A FR2852954B1 (fr) 2003-03-28 2003-03-28 Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
FR03/03812 2003-03-28
PCT/FR2004/000783 WO2004087647A2 (fr) 2003-03-28 2004-03-29 Derives de quinoleines-4-substituees avec une activite antimicrobienne

Publications (1)

Publication Number Publication Date
AU2004226207A1 true AU2004226207A1 (en) 2004-10-14

Family

ID=32947235

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004226207A Abandoned AU2004226207A1 (en) 2003-03-28 2004-03-29 4-substituted quinolein derivatives with antimicrobial activity

Country Status (13)

Country Link
EP (1) EP1611127A2 (fr)
JP (1) JP2006522779A (fr)
KR (1) KR20050115321A (fr)
CN (1) CN1795191A (fr)
AR (1) AR043941A1 (fr)
AU (1) AU2004226207A1 (fr)
CA (1) CA2520764A1 (fr)
EA (1) EA010403B1 (fr)
FR (1) FR2852954B1 (fr)
HR (1) HRP20050855A2 (fr)
RS (1) RS20050806A (fr)
TW (1) TW200505899A (fr)
WO (1) WO2004087647A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004289616B2 (en) * 2003-11-10 2010-08-05 Eli Lilly And Company Morpholine derivatives as norepinephrine reuptake inhibitors

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2816618B1 (fr) * 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
TW200409637A (en) 2002-06-26 2004-06-16 Glaxo Group Ltd Compounds
AR040335A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto
EP1560821B8 (fr) 2002-11-05 2010-05-19 Glaxo Group Limited Agents antibacteriens
AU2003294565A1 (en) 2002-12-04 2004-06-23 Glaxo Group Limited Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents
EP1796466A4 (fr) 2004-06-15 2009-09-02 Glaxo Group Ltd Agents antibacteriens
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
EP2001887B1 (fr) 2006-04-06 2010-09-15 Glaxo Group Limited Derives de pyrrolo-quinoxalinone en tant qu'agents antibacteriens
EP1992628A1 (fr) 2007-05-18 2008-11-19 Glaxo Group Limited Dérivés et analogues de N-éthylquinolones et N-éthylazaquinolones
EP2080761A1 (fr) 2008-01-18 2009-07-22 Glaxo Group Limited Composés
TWI429643B (zh) * 2008-02-22 2014-03-11 Actelion Pharmaceuticals Ltd 唑啶酮衍生物
EP2352734A1 (fr) 2008-10-17 2011-08-10 Glaxo Group Limited Composés azotés tricycliques utilisés comme agents antibactériens
JP5653935B2 (ja) 2009-01-15 2015-01-14 グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ 抗菌薬として有用なナフチリジン―２（１ｈ）−オン化合物
AR089929A1 (es) 2012-02-10 2014-10-01 Actelion Pharmaceuticals Ltd Proceso para manufacturar un derivado de naftiridina
AR101674A1 (es) 2014-08-22 2017-01-04 Glaxosmithkline Ip Dev Ltd Uso de un compuesto tricíclico que contiene nitrógeno
TW201722965A (zh) 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 用於抗菌應用之化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9917408D0 (en) * 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB0012240D0 (en) * 2000-05-19 2000-07-12 Merck Sharp & Dohme Therapeutic agents
FR2816618B1 (fr) * 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
WO2002055516A2 (fr) * 2001-01-11 2002-07-18 Bristol Myers Squibb Co Inhibiteurs cycliques 1,1-disubstitues des metalloproteases matricielles et de tnf-$g(a)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004289616B2 (en) * 2003-11-10 2010-08-05 Eli Lilly And Company Morpholine derivatives as norepinephrine reuptake inhibitors

Also Published As

Publication number Publication date
TW200505899A (en) 2005-02-16
EP1611127A2 (fr) 2006-01-04
KR20050115321A (ko) 2005-12-07
WO2004087647A3 (fr) 2005-01-27
FR2852954B1 (fr) 2006-07-14
FR2852954A1 (fr) 2004-10-01
AR043941A1 (es) 2005-08-17
JP2006522779A (ja) 2006-10-05
RS20050806A (en) 2007-12-31
CA2520764A1 (fr) 2004-10-14
WO2004087647A2 (fr) 2004-10-14
EA200501526A1 (ru) 2006-04-28
CN1795191A (zh) 2006-06-28
EA010403B1 (ru) 2008-08-29
HRP20050855A2 (en) 2005-12-31

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period