CN1795191A - 4－取代喹啉衍生物、制备方法和中间体以及含有其的药物组合物 - Google Patents

4－取代喹啉衍生物、制备方法和中间体以及含有其的药物组合物 Download PDF

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Publication number
CN1795191A
CN1795191A CNA2004800145109A CN200480014510A CN1795191A CN 1795191 A CN1795191 A CN 1795191A CN A2004800145109 A CNA2004800145109 A CN A2004800145109A CN 200480014510 A CN200480014510 A CN 200480014510A CN 1795191 A CN1795191 A CN 1795191A
Authority
CN
China
Prior art keywords
alkyl
group
heteroaryl
phenyl
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2004800145109A
Other languages
English (en)
Chinese (zh)
Inventor
安东尼·比戈
米歇尔·舍韦
优素福·埃尔艾哈迈德
让-吕克·马勒融
让－保罗·马丁
塞尔日·米格纳尼
居伊·潘特尔
巴蒂斯特·罗南
米歇尔·塔巴尔
法布里斯·维维亚尼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of CN1795191A publication Critical patent/CN1795191A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CNA2004800145109A 2003-03-28 2004-03-29 4－取代喹啉衍生物、制备方法和中间体以及含有其的药物组合物 Pending CN1795191A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR03/03812 2003-03-28
FR0303812A FR2852954B1 (fr) 2003-03-28 2003-03-28 Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
CN1795191A true CN1795191A (zh) 2006-06-28

Family

ID=32947235

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800145109A Pending CN1795191A (zh) 2003-03-28 2004-03-29 4－取代喹啉衍生物、制备方法和中间体以及含有其的药物组合物

Country Status (13)

Country Link
EP (1) EP1611127A2 (fr)
JP (1) JP2006522779A (fr)
KR (1) KR20050115321A (fr)
CN (1) CN1795191A (fr)
AR (1) AR043941A1 (fr)
AU (1) AU2004226207A1 (fr)
CA (1) CA2520764A1 (fr)
EA (1) EA010403B1 (fr)
FR (1) FR2852954B1 (fr)
HR (1) HRP20050855A2 (fr)
RS (1) RS20050806A (fr)
TW (1) TW200505899A (fr)
WO (1) WO2004087647A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2816618B1 (fr) * 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
TW200406413A (en) 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
DE60331849D1 (de) 2002-11-05 2010-05-06 Glaxosmithkline Llc Antibakterielle wirkstoffe
EP1567520B1 (fr) 2002-12-04 2008-10-15 Glaxo Group Limited Quinoleines et derives nitrogenes de ces composes ainsi que leur utilisation en tant qu'agents antibacteriens
GB0326148D0 (en) * 2003-11-10 2003-12-17 Lilly Co Eli Morpholine derivatives
EP1796466A4 (fr) 2004-06-15 2009-09-02 Glaxo Group Ltd Agents antibacteriens
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
DE602007009205D1 (de) 2006-04-06 2010-10-28 Glaxo Group Ltd Pyrrolochinoxalinonderivate als antibakterielle mittel
EP1992628A1 (fr) 2007-05-18 2008-11-19 Glaxo Group Limited Dérivés et analogues de N-éthylquinolones et N-éthylazaquinolones
EP2080761A1 (fr) 2008-01-18 2009-07-22 Glaxo Group Limited Composés
BRPI0908208A2 (pt) * 2008-02-22 2015-08-25 Actelion Pharmaceuticals Ltd Composto derivado de oxazolidinona, medicamento, composição farmacêutica que o contém e uso desse composto.
JP2012505866A (ja) 2008-10-17 2012-03-08 グラクソ グループ リミテッド 抗菌剤として使用される三環式窒素化合物
WO2010081874A1 (fr) 2009-01-15 2010-07-22 Glaxo Group Limited Composés naphthyridine-2(1h)-one utiles comme antibactériens
AR089929A1 (es) 2012-02-10 2014-10-01 Actelion Pharmaceuticals Ltd Proceso para manufacturar un derivado de naftiridina
BR112017003705B1 (pt) 2014-08-22 2022-07-12 Glaxosmithkline Intellectual Property Development Limited Compostos contendo nitrogênio tricíclicos para o tratamento de infecção por neisseria gonorrhoea
TW201722965A (zh) 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 用於抗菌應用之化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9917408D0 (en) * 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB0012240D0 (en) * 2000-05-19 2000-07-12 Merck Sharp & Dohme Therapeutic agents
FR2816618B1 (fr) * 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
WO2002055516A2 (fr) * 2001-01-11 2002-07-18 Bristol Myers Squibb Co Inhibiteurs cycliques 1,1-disubstitues des metalloproteases matricielles et de tnf-$g(a)

Also Published As

Publication number Publication date
WO2004087647A3 (fr) 2005-01-27
TW200505899A (en) 2005-02-16
AU2004226207A1 (en) 2004-10-14
CA2520764A1 (fr) 2004-10-14
WO2004087647A2 (fr) 2004-10-14
KR20050115321A (ko) 2005-12-07
JP2006522779A (ja) 2006-10-05
EP1611127A2 (fr) 2006-01-04
AR043941A1 (es) 2005-08-17
EA200501526A1 (ru) 2006-04-28
FR2852954B1 (fr) 2006-07-14
HRP20050855A2 (en) 2005-12-31
EA010403B1 (ru) 2008-08-29
RS20050806A (en) 2007-12-31
FR2852954A1 (fr) 2004-10-01

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