CA2520764A1 - Derives de quinoleines-4-substituees avec une activite antimicrobienne - Google Patents

Derives de quinoleines-4-substituees avec une activite antimicrobienne Download PDF

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Publication number
CA2520764A1
CA2520764A1 CA002520764A CA2520764A CA2520764A1 CA 2520764 A1 CA2520764 A1 CA 2520764A1 CA 002520764 A CA002520764 A CA 002520764A CA 2520764 A CA2520764 A CA 2520764A CA 2520764 A1 CA2520764 A1 CA 2520764A1
Authority
CA
Canada
Prior art keywords
methoxyquinolin
propyl
fluoro
alkyl
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002520764A
Other languages
English (en)
Inventor
Antony Bigot
Michel Cheve
Youssef El Ahmad
Jean-Luc Malleron
Jean-Paul Martin
Serge Mignani
Guy Pantel
Baptiste Ronan
Michel Tabart
Fabrice Viviani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novexel SA
Original Assignee
Aventis Pharma S.A.
Antony Bigot
Michel Cheve
Youssef El Ahmad
Jean-Luc Malleron
Jean-Paul Martin
Serge Mignani
Guy Pantel
Baptiste Ronan
Michel Tabart
Fabrice Viviani
Novexel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma S.A., Antony Bigot, Michel Cheve, Youssef El Ahmad, Jean-Luc Malleron, Jean-Paul Martin, Serge Mignani, Guy Pantel, Baptiste Ronan, Michel Tabart, Fabrice Viviani, Novexel filed Critical Aventis Pharma S.A.
Publication of CA2520764A1 publication Critical patent/CA2520764A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
CA002520764A 2003-03-28 2004-03-29 Derives de quinoleines-4-substituees avec une activite antimicrobienne Abandoned CA2520764A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0303812A FR2852954B1 (fr) 2003-03-28 2003-03-28 Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
FR03/03812 2003-03-28
PCT/FR2004/000783 WO2004087647A2 (fr) 2003-03-28 2004-03-29 Derives de quinoleines-4-substituees avec une activite antimicrobienne

Publications (1)

Publication Number Publication Date
CA2520764A1 true CA2520764A1 (fr) 2004-10-14

Family

ID=32947235

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002520764A Abandoned CA2520764A1 (fr) 2003-03-28 2004-03-29 Derives de quinoleines-4-substituees avec une activite antimicrobienne

Country Status (13)

Country Link
EP (1) EP1611127A2 (fr)
JP (1) JP2006522779A (fr)
KR (1) KR20050115321A (fr)
CN (1) CN1795191A (fr)
AR (1) AR043941A1 (fr)
AU (1) AU2004226207A1 (fr)
CA (1) CA2520764A1 (fr)
EA (1) EA010403B1 (fr)
FR (1) FR2852954B1 (fr)
HR (1) HRP20050855A2 (fr)
RS (1) RS20050806A (fr)
TW (1) TW200505899A (fr)
WO (1) WO2004087647A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2816618B1 (fr) * 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
AR040335A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto
WO2004096982A2 (fr) 2002-11-05 2004-11-11 Smithkline Beecham Corporation Agents antibacteriens
US7491714B2 (en) 2002-12-04 2009-02-17 Glaxo Group Limited Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents
GB0326148D0 (en) * 2003-11-10 2003-12-17 Lilly Co Eli Morpholine derivatives
WO2006002047A2 (fr) 2004-06-15 2006-01-05 Glaxo Group Limited Agents antibacteriens
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
DE602007009205D1 (de) 2006-04-06 2010-10-28 Glaxo Group Ltd Pyrrolochinoxalinonderivate als antibakterielle mittel
EP1992628A1 (fr) 2007-05-18 2008-11-19 Glaxo Group Limited Dérivés et analogues de N-éthylquinolones et N-éthylazaquinolones
EP2080761A1 (fr) 2008-01-18 2009-07-22 Glaxo Group Limited Composés
CA2713187C (fr) * 2008-02-22 2016-06-07 Actelion Pharmaceuticals Ltd Derives d'oxazolidinone
US20110275661A1 (en) 2008-10-17 2011-11-10 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
ES2561631T3 (es) 2009-01-15 2016-02-29 Glaxo Group Limited Compuestos de naftiridin-2(1H)-ona útiles como agentes antibacterianos
AR089929A1 (es) 2012-02-10 2014-10-01 Actelion Pharmaceuticals Ltd Proceso para manufacturar un derivado de naftiridina
JP6546654B2 (ja) 2014-08-22 2019-07-17 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ 淋菌感染を治療するための三環式含窒素化合物
TW201722965A (zh) 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 用於抗菌應用之化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9917408D0 (en) * 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB0012240D0 (en) * 2000-05-19 2000-07-12 Merck Sharp & Dohme Therapeutic agents
FR2816618B1 (fr) * 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
EP1355901A2 (fr) * 2001-01-11 2003-10-29 Bristol-Myers Squibb Pharma Company Inhibiteurs cycliques 1,1-disubstitues des metalloproteases matricielles et de tnf-$g(a)

Also Published As

Publication number Publication date
FR2852954A1 (fr) 2004-10-01
TW200505899A (en) 2005-02-16
HRP20050855A2 (en) 2005-12-31
AR043941A1 (es) 2005-08-17
RS20050806A (en) 2007-12-31
EA200501526A1 (ru) 2006-04-28
KR20050115321A (ko) 2005-12-07
EP1611127A2 (fr) 2006-01-04
CN1795191A (zh) 2006-06-28
EA010403B1 (ru) 2008-08-29
WO2004087647A2 (fr) 2004-10-14
AU2004226207A1 (en) 2004-10-14
FR2852954B1 (fr) 2006-07-14
JP2006522779A (ja) 2006-10-05
WO2004087647A3 (fr) 2005-01-27

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued