EA010403B1 - Производные 4-замещенных хинолинов, способ и промежуточные продукты для их получения и содержащие их фармацевтические композиции - Google Patents

Производные 4-замещенных хинолинов, способ и промежуточные продукты для их получения и содержащие их фармацевтические композиции Download PDF

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Publication number
EA010403B1
EA010403B1 EA200501526A EA200501526A EA010403B1 EA 010403 B1 EA010403 B1 EA 010403B1 EA 200501526 A EA200501526 A EA 200501526A EA 200501526 A EA200501526 A EA 200501526A EA 010403 B1 EA010403 B1 EA 010403B1
Authority
EA
Eurasian Patent Office
Prior art keywords
propyl
fluoro
methoxy
quinolinyl
difluorophenyl
Prior art date
Application number
EA200501526A
Other languages
English (en)
Russian (ru)
Other versions
EA200501526A1 (ru
Inventor
Антони Биго
Мишель Шев
Юссеф Эль Амад
Жан-Люк Маллерон
Жан-Поль Мартэн
Серж Миньяни
Ги Пантель
Батист Ронан
Мишель Табар
Фабрис Вивьяни
Original Assignee
Новексель
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Новексель filed Critical Новексель
Publication of EA200501526A1 publication Critical patent/EA200501526A1/ru
Publication of EA010403B1 publication Critical patent/EA010403B1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EA200501526A 2003-03-28 2004-03-29 Производные 4-замещенных хинолинов, способ и промежуточные продукты для их получения и содержащие их фармацевтические композиции EA010403B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0303812A FR2852954B1 (fr) 2003-03-28 2003-03-28 Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2004/000783 WO2004087647A2 (fr) 2003-03-28 2004-03-29 Derives de quinoleines-4-substituees avec une activite antimicrobienne

Publications (2)

Publication Number Publication Date
EA200501526A1 EA200501526A1 (ru) 2006-04-28
EA010403B1 true EA010403B1 (ru) 2008-08-29

Family

ID=32947235

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200501526A EA010403B1 (ru) 2003-03-28 2004-03-29 Производные 4-замещенных хинолинов, способ и промежуточные продукты для их получения и содержащие их фармацевтические композиции

Country Status (13)

Country Link
EP (1) EP1611127A2 (fr)
JP (1) JP2006522779A (fr)
KR (1) KR20050115321A (fr)
CN (1) CN1795191A (fr)
AR (1) AR043941A1 (fr)
AU (1) AU2004226207A1 (fr)
CA (1) CA2520764A1 (fr)
EA (1) EA010403B1 (fr)
FR (1) FR2852954B1 (fr)
HR (1) HRP20050855A2 (fr)
RS (1) RS20050806A (fr)
TW (1) TW200505899A (fr)
WO (1) WO2004087647A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2816618B1 (fr) * 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
AR040335A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
DE60331849D1 (de) 2002-11-05 2010-05-06 Glaxosmithkline Llc Antibakterielle wirkstoffe
EP1567520B1 (fr) 2002-12-04 2008-10-15 Glaxo Group Limited Quinoleines et derives nitrogenes de ces composes ainsi que leur utilisation en tant qu'agents antibacteriens
GB0326148D0 (en) 2003-11-10 2003-12-17 Lilly Co Eli Morpholine derivatives
EP1796466A4 (fr) 2004-06-15 2009-09-02 Glaxo Group Ltd Agents antibacteriens
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
US7709483B2 (en) 2006-04-06 2010-05-04 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
EP1992628A1 (fr) 2007-05-18 2008-11-19 Glaxo Group Limited Dérivés et analogues de N-éthylquinolones et N-éthylazaquinolones
EP2080761A1 (fr) 2008-01-18 2009-07-22 Glaxo Group Limited Composés
JP5404652B2 (ja) * 2008-02-22 2014-02-05 アクテリオン ファーマシューティカルズ リミテッド オキサゾリジノン誘導体
WO2010043714A1 (fr) 2008-10-17 2010-04-22 Glaxo Group Limited Composés azotés tricycliques utilisés comme agents antibactériens
WO2010081874A1 (fr) 2009-01-15 2010-07-22 Glaxo Group Limited Composés naphthyridine-2(1h)-one utiles comme antibactériens
AR089929A1 (es) 2012-02-10 2014-10-01 Actelion Pharmaceuticals Ltd Proceso para manufacturar un derivado de naftiridina
KR20170043603A (ko) 2014-08-22 2017-04-21 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 네이세리아 고노레아에 감염을 치료하기 위한 트리시클릭 질소 함유 화합물
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001007432A2 (fr) * 1999-07-23 2001-02-01 Smithkline Beecham P.L.C. Composes
FR2816618A1 (fr) * 2000-11-15 2002-05-17 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0012240D0 (en) * 2000-05-19 2000-07-12 Merck Sharp & Dohme Therapeutic agents
EP1355901A2 (fr) * 2001-01-11 2003-10-29 Bristol-Myers Squibb Pharma Company Inhibiteurs cycliques 1,1-disubstitues des metalloproteases matricielles et de tnf-$g(a)

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001007432A2 (fr) * 1999-07-23 2001-02-01 Smithkline Beecham P.L.C. Composes
FR2816618A1 (fr) * 2000-11-15 2002-05-17 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent

Also Published As

Publication number Publication date
FR2852954B1 (fr) 2006-07-14
EP1611127A2 (fr) 2006-01-04
WO2004087647A3 (fr) 2005-01-27
EA200501526A1 (ru) 2006-04-28
FR2852954A1 (fr) 2004-10-01
RS20050806A (en) 2007-12-31
JP2006522779A (ja) 2006-10-05
KR20050115321A (ko) 2005-12-07
HRP20050855A2 (en) 2005-12-31
CA2520764A1 (fr) 2004-10-14
WO2004087647A2 (fr) 2004-10-14
TW200505899A (en) 2005-02-16
AR043941A1 (es) 2005-08-17
AU2004226207A1 (en) 2004-10-14
CN1795191A (zh) 2006-06-28

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM