AU2003237302B8 - Heteroaryl compounds which inhibit leukocyte adhesion mediated by alpha-4 integrins - Google Patents
Heteroaryl compounds which inhibit leukocyte adhesion mediated by alpha-4 integrins Download PDFInfo
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- AU2003237302B8 AU2003237302B8 AU2003237302A AU2003237302A AU2003237302B8 AU 2003237302 B8 AU2003237302 B8 AU 2003237302B8 AU 2003237302 A AU2003237302 A AU 2003237302A AU 2003237302 A AU2003237302 A AU 2003237302A AU 2003237302 B8 AU2003237302 B8 AU 2003237302B8
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- Prior art keywords
- propionic acid
- ylamino
- diethylamino
- compound
- pyrimidin
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38324402P | 2002-05-24 | 2002-05-24 | |
| US60/383,244 | 2002-05-24 | ||
| PCT/US2003/017150 WO2003099231A2 (en) | 2002-05-24 | 2003-05-27 | Heteroaryl compounds which inhibit leukocyte adhesion mediated by alpha-4 integrins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| AU2003237302A1 AU2003237302A1 (en) | 2003-12-12 |
| AU2003237302B2 AU2003237302B2 (en) | 2008-03-06 |
| AU2003237302B8 true AU2003237302B8 (en) | 2008-04-03 |
Family
ID=29584533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003237302A Ceased AU2003237302B8 (en) | 2002-05-24 | 2003-05-27 | Heteroaryl compounds which inhibit leukocyte adhesion mediated by alpha-4 integrins |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US7335663B2 (enExample) |
| EP (1) | EP1507533B1 (enExample) |
| JP (1) | JP4413135B2 (enExample) |
| CN (1) | CN1311829C (enExample) |
| AT (1) | ATE464298T1 (enExample) |
| AU (1) | AU2003237302B8 (enExample) |
| BR (1) | BR0309619A (enExample) |
| CA (1) | CA2480756A1 (enExample) |
| DE (1) | DE60332109D1 (enExample) |
| EA (1) | EA008180B1 (enExample) |
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| EP1996559A1 (en) | 2006-02-27 | 2008-12-03 | Elan Pharmaceuticals Inc. | Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by vla-4 |
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| CN112969687B (zh) | 2018-10-30 | 2024-08-23 | 吉利德科学公司 | 作为α4β7整合素抑制剂的喹啉衍生物 |
| CA3114240C (en) | 2018-10-30 | 2023-09-05 | Gilead Sciences, Inc. | Imidazopyridine derivatives as alpha4beta7 integrin inhibitors |
| CN111197057B (zh) * | 2018-11-19 | 2024-04-19 | 中国科学院分子细胞科学卓越创新中心 | 调控免疫细胞迁移的组合物和方法 |
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2003
- 2003-05-26 TW TW092114184A patent/TW200307671A/zh unknown
- 2003-05-27 AU AU2003237302A patent/AU2003237302B8/en not_active Ceased
- 2003-05-27 WO PCT/US2003/017150 patent/WO2003099231A2/en not_active Ceased
- 2003-05-27 EP EP03736768A patent/EP1507533B1/en not_active Expired - Lifetime
- 2003-05-27 EA EA200401561A patent/EA008180B1/ru not_active IP Right Cessation
- 2003-05-27 AT AT03736768T patent/ATE464298T1/de not_active IP Right Cessation
- 2003-05-27 JP JP2004506758A patent/JP4413135B2/ja not_active Expired - Fee Related
- 2003-05-27 CN CNB038112582A patent/CN1311829C/zh not_active Expired - Fee Related
- 2003-05-27 DE DE60332109T patent/DE60332109D1/de not_active Expired - Lifetime
- 2003-05-27 MX MXPA04011657A patent/MXPA04011657A/es active IP Right Grant
- 2003-05-27 US US10/494,788 patent/US7335663B2/en not_active Expired - Fee Related
- 2003-05-27 US US10/447,208 patent/US7008949B2/en not_active Expired - Fee Related
- 2003-05-27 CA CA002480756A patent/CA2480756A1/en not_active Abandoned
- 2003-05-27 BR BR0309619-0A patent/BR0309619A/pt not_active IP Right Cessation
- 2003-05-27 NZ NZ535723A patent/NZ535723A/en unknown
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2004
- 2004-09-28 IL IL164323A patent/IL164323A/en not_active IP Right Cessation
- 2004-10-01 ZA ZA200407944A patent/ZA200407944B/en unknown
- 2004-12-01 NO NO20045276A patent/NO20045276L/no not_active Application Discontinuation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000043372A1 (en) * | 1999-01-22 | 2000-07-27 | Elan Pharmaceuticals, Inc. | Acyl derivatives which treat vla-4 related disorders |
Also Published As
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|---|---|
| IL164323A0 (en) | 2005-12-18 |
| MXPA04011657A (es) | 2005-08-18 |
| US7008949B2 (en) | 2006-03-07 |
| US20050130999A1 (en) | 2005-06-16 |
| ATE464298T1 (de) | 2010-04-15 |
| CN1652789A (zh) | 2005-08-10 |
| AU2003237302A1 (en) | 2003-12-12 |
| AU2003237302B2 (en) | 2008-03-06 |
| EA200401561A1 (ru) | 2005-06-30 |
| EP1507533B1 (en) | 2010-04-14 |
| US7335663B2 (en) | 2008-02-26 |
| CA2480756A1 (en) | 2003-12-04 |
| EP1507533A2 (en) | 2005-02-23 |
| NZ535723A (en) | 2005-08-26 |
| EA008180B1 (ru) | 2007-04-27 |
| DE60332109D1 (de) | 2010-05-27 |
| TW200307671A (en) | 2003-12-16 |
| CN1311829C (zh) | 2007-04-25 |
| US20040142954A1 (en) | 2004-07-22 |
| JP4413135B2 (ja) | 2010-02-10 |
| WO2003099231A3 (en) | 2004-01-22 |
| NO20045276L (no) | 2004-12-01 |
| BR0309619A (pt) | 2005-06-28 |
| JP2005529155A (ja) | 2005-09-29 |
| IL164323A (en) | 2010-02-17 |
| ZA200407944B (en) | 2006-07-26 |
| EP1507533A4 (en) | 2007-05-23 |
| WO2003099231A2 (en) | 2003-12-04 |
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