AU2001237556B2 - 1,5-benzothiazepines and their use as hypolipidaemics - Google Patents

1,5-benzothiazepines and their use as hypolipidaemics Download PDF

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Publication number
AU2001237556B2
AU2001237556B2 AU2001237556A AU2001237556A AU2001237556B2 AU 2001237556 B2 AU2001237556 B2 AU 2001237556B2 AU 2001237556 A AU2001237556 A AU 2001237556A AU 2001237556 A AU2001237556 A AU 2001237556A AU 2001237556 B2 AU2001237556 B2 AU 2001237556B2
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AU
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Prior art keywords
solvate
formula
salt
pharmaceutically acceptable
compound
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Ceased
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AU2001237556A
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AU2001237556A1 (en
Inventor
David Blomberg
Michael Dahlstrom
Ingemar Starke
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AstraZeneca AB
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AstraZeneca AB
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Publication of AU2001237556A1 publication Critical patent/AU2001237556A1/en
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Publication of AU2001237556B2 publication Critical patent/AU2001237556B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2001237556A 2000-03-08 2001-03-05 1,5-benzothiazepines and their use as hypolipidaemics Ceased AU2001237556B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0000772A SE0000772D0 (sv) 2000-03-08 2000-03-08 Chemical compounds
SE0000772-4 2000-03-08
PCT/GB2001/000909 WO2001066533A1 (en) 2000-03-08 2001-03-05 1,5-benzothiazepines and their use as hypolipidaemics

Publications (2)

Publication Number Publication Date
AU2001237556A1 AU2001237556A1 (en) 2001-11-29
AU2001237556B2 true AU2001237556B2 (en) 2004-10-07

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001237556A Ceased AU2001237556B2 (en) 2000-03-08 2001-03-05 1,5-benzothiazepines and their use as hypolipidaemics
AU3755601A Pending AU3755601A (en) 2000-03-08 2001-03-05 1,5-benzothiazepines and their use as hypolipidaemics

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU3755601A Pending AU3755601A (en) 2000-03-08 2001-03-05 1,5-benzothiazepines and their use as hypolipidaemics

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Country Link
US (1) US6906058B2 (enExample)
EP (1) EP1263747B1 (enExample)
JP (1) JP5204361B2 (enExample)
KR (1) KR20020079990A (enExample)
CN (1) CN1416425A (enExample)
AT (1) ATE283266T1 (enExample)
AU (2) AU2001237556B2 (enExample)
BR (1) BR0109011A (enExample)
CA (1) CA2401055A1 (enExample)
DE (1) DE60107395T2 (enExample)
IL (1) IL151296A0 (enExample)
MX (1) MXPA02008600A (enExample)
NO (1) NO20024217L (enExample)
NZ (1) NZ520951A (enExample)
SE (1) SE0000772D0 (enExample)
WO (1) WO2001066533A1 (enExample)
ZA (1) ZA200206739B (enExample)

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WO1996016051A1 (en) * 1994-11-17 1996-05-30 The Wellcome Foundation Limited Hypolipidemic benzothiazepines
WO1999035135A1 (en) * 1998-01-10 1999-07-15 Glaxo Group Limited Hypolipidemic benzothiazepine compounds

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US20030166927A1 (en) 2003-09-04
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DE60107395D1 (de) 2004-12-30
EP1263747A1 (en) 2002-12-11
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NO20024217L (no) 2002-10-09
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