ATE537827T1 - Pharmazeutische zubereitung mit hervorragender photostabilität - Google Patents
Pharmazeutische zubereitung mit hervorragender photostabilitätInfo
- Publication number
- ATE537827T1 ATE537827T1 AT06822589T AT06822589T ATE537827T1 AT E537827 T1 ATE537827 T1 AT E537827T1 AT 06822589 T AT06822589 T AT 06822589T AT 06822589 T AT06822589 T AT 06822589T AT E537827 T1 ATE537827 T1 AT E537827T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical preparation
- pitavastatin
- excellent photostability
- photostability
- hmg
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 3
- 229960002797 pitavastatin Drugs 0.000 abstract 4
- VGYFMXBACGZSIL-MCBHFWOFSA-N pitavastatin Chemical compound OC(=O)C[C@H](O)C[C@H](O)\C=C\C1=C(C2CC2)N=C2C=CC=CC2=C1C1=CC=C(F)C=C1 VGYFMXBACGZSIL-MCBHFWOFSA-N 0.000 abstract 3
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 abstract 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000003086 colorant Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 abstract 1
- -1 pitavastatin compound Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2813—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/501—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005316758 | 2005-10-31 | ||
| JP2006021632 | 2006-10-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE537827T1 true ATE537827T1 (de) | 2012-01-15 |
Family
ID=38005744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06822589T ATE537827T1 (de) | 2005-10-31 | 2006-10-30 | Pharmazeutische zubereitung mit hervorragender photostabilität |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20090041843A1 (de) |
| EP (1) | EP1944029B1 (de) |
| JP (3) | JP5166876B2 (de) |
| KR (1) | KR101409087B1 (de) |
| CN (1) | CN101300010B (de) |
| AT (1) | ATE537827T1 (de) |
| AU (1) | AU2006309826B2 (de) |
| CA (1) | CA2626309A1 (de) |
| CY (1) | CY1112477T1 (de) |
| DK (1) | DK1944029T3 (de) |
| EA (1) | EA016713B1 (de) |
| ES (1) | ES2375643T3 (de) |
| IL (1) | IL190346A (de) |
| NO (1) | NO20081526L (de) |
| NZ (1) | NZ566872A (de) |
| PL (1) | PL1944029T3 (de) |
| PT (1) | PT1944029E (de) |
| SG (1) | SG196789A1 (de) |
| SI (1) | SI1944029T1 (de) |
| TW (1) | TWI422375B (de) |
| UA (1) | UA92920C2 (de) |
| WO (1) | WO2007052592A1 (de) |
| ZA (1) | ZA200803655B (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5683058B2 (ja) * | 2007-04-27 | 2015-03-11 | ニプロ株式会社 | 経口固形製剤及びその製造方法 |
| CN102300563A (zh) * | 2009-01-29 | 2011-12-28 | 大日本住友制药株式会社 | 具有内核的口腔崩解片剂 |
| JP5744412B2 (ja) * | 2010-03-26 | 2015-07-08 | テバ製薬株式会社 | フロセミド製剤 |
| JP2012041290A (ja) * | 2010-08-18 | 2012-03-01 | Sawai Pharmaceutical Co Ltd | ラフチジン含有固形製剤 |
| JP5809467B2 (ja) * | 2011-07-12 | 2015-11-11 | エルメッド エーザイ株式会社 | ピタバスタチン含有組成物及びその製造方法 |
| JP5844574B2 (ja) * | 2011-08-10 | 2016-01-20 | 共和薬品工業株式会社 | ピタバスタチンを含有する安定化された薬物組成物 |
| JP5844573B2 (ja) * | 2011-08-10 | 2016-01-20 | 共和薬品工業株式会社 | ピタバスタチンを含有する錠剤 |
| TWI636783B (zh) * | 2012-04-18 | 2018-10-01 | 友霖生技醫藥股份有限公司 | 含匹伐他汀（ｐｉｔａｖａｓｔａｔｉｎ）穩定配方的醫藥組合物 |
| JP5190159B1 (ja) | 2012-08-08 | 2013-04-24 | 興和株式会社 | 医薬 |
| IL296484B2 (en) | 2013-06-06 | 2025-03-01 | Fibrogen Inc | Pharmaceutical formulations of HIF hydroxylase inhibitor |
| JP6150703B2 (ja) * | 2013-10-08 | 2017-06-21 | ダイト株式会社 | ピタバスタチンカルシウム塩の分解抑制方法 |
| JP6243265B2 (ja) * | 2014-03-20 | 2017-12-06 | 日医工株式会社 | ロスバスタチン含有医薬製剤 |
| JP6433400B2 (ja) * | 2014-09-30 | 2018-12-05 | 株式会社三和化学研究所 | ＨＭＧ−ＣｏＡレダクターゼ阻害薬を含有する医薬製剤 |
| CN104367560A (zh) * | 2014-10-23 | 2015-02-25 | 万全万特制药江苏有限公司 | 一种新型匹伐他汀钙口腔崩解片组合物及其制备方法 |
| WO2016148264A1 (ja) * | 2015-03-19 | 2016-09-22 | 第一三共株式会社 | 着色剤を含有する固形製剤 |
| KR102426821B1 (ko) | 2015-03-19 | 2022-07-28 | 다이이찌 산쿄 가부시키가이샤 | 항산화제를 함유하는 고형 제제 |
| JP6072884B2 (ja) * | 2015-11-19 | 2017-02-01 | 共和薬品工業株式会社 | ピタバスタチンを含有する製剤 |
| EP3574906B1 (de) | 2017-01-30 | 2024-07-03 | Shionogi & Co., Ltd. | Feste zubereitung mit chinazolinderivat |
| TWI795462B (zh) | 2017-11-17 | 2023-03-11 | 日商鹽野義製藥股份有限公司 | 光安定性及溶出性優異的醫藥製劑 |
| JP7166754B2 (ja) | 2017-11-22 | 2022-11-08 | 沢井製薬株式会社 | ダサチニブ無水物含有製剤 |
| CN108543075A (zh) * | 2018-04-29 | 2018-09-18 | 广东伊茗药业有限公司 | 一种光稳定性优异的医药制剂 |
| BR112021001008A2 (pt) | 2018-07-30 | 2021-04-20 | Daiichi Sankyo Company, Limited | comprimido de fármaco |
| EA202191371A1 (ru) * | 2018-12-14 | 2021-12-27 | Фуджифилм Корпорэйшн | Фармацевтическая композиция и способ ее получения |
| CN112402388A (zh) * | 2019-08-05 | 2021-02-26 | 江苏亚虹医药科技股份有限公司 | 一种用于治疗膀胱癌的口服固体制剂及其制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU432703A3 (de) * | 1971-08-24 | 1974-06-15 | Фридрих Боссерт, Вульф Фатер, Курт Бауер | |
| JPS5522645A (en) * | 1978-08-07 | 1980-02-18 | Fujisawa Pharmaceut Co Ltd | Soft capsule for encapsulation of light-unstable compound |
| JPS6059205B2 (ja) * | 1981-12-24 | 1985-12-24 | 帝三製薬株式会社 | 光不安定性薬物を包容するための軟カプセルの製造方法 |
| JPS61275214A (ja) * | 1985-05-28 | 1986-12-05 | Sawai Seiyaku Kk | 経口用メナテトレノン軟カプセル |
| JP2569746B2 (ja) * | 1987-08-20 | 1997-01-08 | 日産化学工業株式会社 | キノリン系メバロノラクトン類 |
| DE4446470A1 (de) * | 1994-12-23 | 1996-06-27 | Basf Ag | Verfahren zur Herstellung von teilbaren Tabletten |
| US6465477B1 (en) * | 1997-08-18 | 2002-10-15 | Kowa Company, Ltd. | Stable pharmaceutical composition |
| EP0901787B1 (de) * | 1997-09-10 | 2003-05-28 | Takeda Chemical Industries, Ltd. | Stabilisierte pharmazeutische Zusammensetzung |
| JP2000191516A (ja) * | 1998-10-23 | 2000-07-11 | Taisho Pharmaceut Co Ltd | 経口固形組成物 |
| US6569461B1 (en) * | 1999-03-08 | 2003-05-27 | Merck & Co., Inc. | Dihydroxy open-acid and salts of HMG-CoA reductase inhibitors |
| GB0001621D0 (en) * | 2000-01-26 | 2000-03-15 | Astrazeneca Ab | Pharmaceutical compositions |
| US6242003B1 (en) * | 2000-04-13 | 2001-06-05 | Novartis Ag | Organic compounds |
| JP2003104887A (ja) * | 2001-09-28 | 2003-04-09 | Maruko Seiyaku Kk | 光に安定なアラニジピン含有組成物 |
| GB0217306D0 (en) * | 2002-07-25 | 2002-09-04 | Novartis Ag | Compositions comprising organic compounds |
| SI21402A (sl) * | 2003-02-12 | 2004-08-31 | LEK farmacevtska dru�ba d.d. | Obloženi delci in farmacevtske oblike |
| JP5395355B2 (ja) * | 2004-05-21 | 2014-01-22 | アキュ−ブレイク テクノロジーズ インコーポレーテッド | ２個またはそれ以上の単位セグメントを含む医薬錠剤 |
| CN101217944A (zh) * | 2005-04-08 | 2008-07-09 | 艾博特公司 | 包含非诺贝酸和/或其盐的口服药物制剂 |
-
2006
- 2006-10-30 AT AT06822589T patent/ATE537827T1/de active
- 2006-10-30 US US12/088,869 patent/US20090041843A1/en not_active Abandoned
- 2006-10-30 AU AU2006309826A patent/AU2006309826B2/en not_active Ceased
- 2006-10-30 NZ NZ566872A patent/NZ566872A/en not_active IP Right Cessation
- 2006-10-30 ES ES06822589T patent/ES2375643T3/es active Active
- 2006-10-30 CA CA002626309A patent/CA2626309A1/en not_active Abandoned
- 2006-10-30 WO PCT/JP2006/321632 patent/WO2007052592A1/ja not_active Ceased
- 2006-10-30 SG SG2014000640A patent/SG196789A1/en unknown
- 2006-10-30 DK DK06822589.5T patent/DK1944029T3/da active
- 2006-10-30 PL PL06822589T patent/PL1944029T3/pl unknown
- 2006-10-30 JP JP2007542721A patent/JP5166876B2/ja active Active
- 2006-10-30 EA EA200800993A patent/EA016713B1/ru not_active IP Right Cessation
- 2006-10-30 UA UAA200805324A patent/UA92920C2/ru unknown
- 2006-10-30 PT PT06822589T patent/PT1944029E/pt unknown
- 2006-10-30 CN CN2006800407986A patent/CN101300010B/zh active Active
- 2006-10-30 ZA ZA200803655A patent/ZA200803655B/xx unknown
- 2006-10-30 EP EP06822589A patent/EP1944029B1/de active Active
- 2006-10-30 KR KR1020087010413A patent/KR101409087B1/ko active Active
- 2006-10-30 SI SI200631262T patent/SI1944029T1/sl unknown
- 2006-10-31 TW TW095140248A patent/TWI422375B/zh not_active IP Right Cessation
-
2008
- 2008-03-20 IL IL190346A patent/IL190346A/en not_active IP Right Cessation
- 2008-03-28 NO NO20081526A patent/NO20081526L/no not_active Application Discontinuation
-
2012
- 2012-03-09 CY CY20121100247T patent/CY1112477T1/el unknown
- 2012-09-19 JP JP2012205526A patent/JP2012246325A/ja active Pending
- 2012-09-19 JP JP2012205519A patent/JP5677391B2/ja not_active Expired - Fee Related
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