ATE472547T1 - Kondensierte n-heterozyclische verbindungen und ihre verwendung als crf-rezeptor antagonisten. - Google Patents
Kondensierte n-heterozyclische verbindungen und ihre verwendung als crf-rezeptor antagonisten.Info
- Publication number
- ATE472547T1 ATE472547T1 AT04726587T AT04726587T ATE472547T1 AT E472547 T1 ATE472547 T1 AT E472547T1 AT 04726587 T AT04726587 T AT 04726587T AT 04726587 T AT04726587 T AT 04726587T AT E472547 T1 ATE472547 T1 AT E472547T1
- Authority
- AT
- Austria
- Prior art keywords
- condensed
- receptor antagonists
- heterocyclic compounds
- crf receptor
- crf
- Prior art date
Links
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0308208.8A GB0308208D0 (en) | 2003-04-09 | 2003-04-09 | Chemical compounds |
US48532203P | 2003-07-07 | 2003-07-07 | |
PCT/IB2004/001283 WO2004094419A1 (en) | 2003-04-09 | 2004-04-08 | Condensed n-heterocyclic compounds and their use as crf receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE472547T1 true ATE472547T1 (de) | 2010-07-15 |
Family
ID=33312357
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04726237T ATE473226T1 (de) | 2003-04-09 | 2004-04-07 | Kondensierte n-heterozyclische verbindung und ihre verwendung als crf-rezeptor antagonist |
AT04726587T ATE472547T1 (de) | 2003-04-09 | 2004-04-08 | Kondensierte n-heterozyclische verbindungen und ihre verwendung als crf-rezeptor antagonisten. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04726237T ATE473226T1 (de) | 2003-04-09 | 2004-04-07 | Kondensierte n-heterozyclische verbindung und ihre verwendung als crf-rezeptor antagonist |
Country Status (21)
Country | Link |
---|---|
US (2) | US7427630B2 (de) |
EP (3) | EP1611133B1 (de) |
JP (2) | JP4866722B2 (de) |
KR (1) | KR20060021826A (de) |
CN (1) | CN1805958A (de) |
AR (1) | AR044005A1 (de) |
AT (2) | ATE473226T1 (de) |
AU (1) | AU2004232551C1 (de) |
BR (1) | BRPI0409117A (de) |
CA (1) | CA2521929C (de) |
DE (2) | DE602004027998D1 (de) |
GB (1) | GB0308208D0 (de) |
IS (1) | IS8119A (de) |
MA (1) | MA27796A1 (de) |
MX (1) | MXPA05010874A (de) |
NO (1) | NO20055238L (de) |
NZ (1) | NZ542780A (de) |
PL (1) | PL378755A1 (de) |
RU (1) | RU2382785C2 (de) |
TW (1) | TW200508232A (de) |
WO (2) | WO2004094420A1 (de) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0117396D0 (en) | 2001-07-17 | 2001-09-05 | Glaxo Group Ltd | Chemical compounds |
AU2004283196B2 (en) | 2003-09-17 | 2011-08-25 | Janssen Pharmaceutica, N.V. | Fused heterocyclic compounds |
CA2550948A1 (en) * | 2003-12-22 | 2005-07-14 | Sb Pharmco Puerto Rico Inc. | Crf receptor antagonists and methods relating thereto |
WO2005103690A2 (en) * | 2004-04-24 | 2005-11-03 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with corticotropin releasing hormone receptor 2 (crhr2) |
WO2006044821A1 (en) * | 2004-10-19 | 2006-04-27 | Sb Pharmco Puerto Rico Inc. | Crf receptor antagonists and methods relating thereto |
GB0519957D0 (en) * | 2005-09-30 | 2005-11-09 | Sb Pharmco Inc | Chemical compound |
GB0507195D0 (en) * | 2005-04-08 | 2005-05-18 | Sb Pharmco Inc | Process for preparing bicyclic compounds |
GB0507198D0 (en) * | 2005-04-08 | 2005-05-18 | Sb Pharmco Inc | Process for preparing bicyclic compounds |
US7598255B2 (en) | 2005-08-04 | 2009-10-06 | Janssen Pharmaceutica Nv | Pyrimidine compounds as serotonin receptor modulators |
US8088779B2 (en) * | 2005-09-30 | 2012-01-03 | Smithkline Beecham (Cork) Limited | Pyrazolo [1,5-alpha] pyrimidinyl derivatives useful as corticotropin-releasing factor (CRF) receptor antagonists |
US8063050B2 (en) * | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
ATE523499T1 (de) * | 2006-07-06 | 2011-09-15 | Array Biopharma Inc | Cyclopenta [d]-pyrimidine als akt-proteinkinasehemmer |
DE602007011628D1 (de) | 2006-07-06 | 2011-02-10 | Array Biopharma Inc | Dihydrofuropyrimidine als akt-proteinkinaseinhibitoren |
CA2656364C (en) | 2006-07-06 | 2014-11-25 | Array Biopharma Inc. | Dihydrothieno pyrimidines as akt protein kinase inhibitors |
TWI450720B (zh) | 2007-07-05 | 2014-09-01 | Array Biopharma Inc | 作為akt蛋白質激酶抑制劑之嘧啶環戊烷 |
US8846683B2 (en) | 2007-07-05 | 2014-09-30 | Array Biopharma, Inc. | Pyrimidyl cyclopentanes as Akt protein kinase inhibitors |
US9409886B2 (en) | 2007-07-05 | 2016-08-09 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
US8377937B2 (en) | 2007-07-05 | 2013-02-19 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
US20090118276A1 (en) * | 2007-11-02 | 2009-05-07 | Wyeth | Thienopyrimidines, thienopyridines, and pyrrolopyrimidines as b-raf inhibitors |
ES2401685T3 (es) * | 2008-01-09 | 2013-04-23 | Array Biopharma, Inc. | Pirimidil ciclopentano hidroxilado como inhibidor de la proteína quinasa AKT |
AU2009204025B2 (en) * | 2008-01-09 | 2014-02-20 | Array Biopharma Inc. | Hydroxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
AU2009206936A1 (en) * | 2008-01-22 | 2009-07-30 | Takeda Pharmaceutical Company Limited | Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing them |
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