ATE450609T1 - Durch quasizufallsstrukturen und funktionen geführte synthesemethode - Google Patents

Durch quasizufallsstrukturen und funktionen geführte synthesemethode

Info

Publication number
ATE450609T1
ATE450609T1 AT03767480T AT03767480T ATE450609T1 AT E450609 T1 ATE450609 T1 AT E450609T1 AT 03767480 T AT03767480 T AT 03767480T AT 03767480 T AT03767480 T AT 03767480T AT E450609 T1 ATE450609 T1 AT E450609T1
Authority
AT
Austria
Prior art keywords
ccpns
cpns
formation
quasi
functions
Prior art date
Application number
AT03767480T
Other languages
English (en)
Inventor
Alex Gouliaev
Anette Holtmann
Henrik Pedersen
Thomas Franch
Original Assignee
Nuevolution As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuevolution As filed Critical Nuevolution As
Application granted granted Critical
Publication of ATE450609T1 publication Critical patent/ATE450609T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B20/00—Methods specially adapted for identifying library members
    • C40B20/04—Identifying library members by means of a tag, label, or other readable or detectable entity associated with the library members, e.g. decoding processes
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/08—Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/04—Methods of creating libraries, e.g. combinatorial synthesis using dynamic combinatorial chemistry techniques
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
AT03767480T 2002-12-19 2003-12-19 Durch quasizufallsstrukturen und funktionen geführte synthesemethode ATE450609T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US43438602P 2002-12-19 2002-12-19
DKPA200201948 2002-12-19
DKPA200301424 2003-09-30
US50711103P 2003-10-01 2003-10-01
PCT/DK2003/000921 WO2004056994A2 (en) 2002-12-19 2003-12-19 Quasirandom structure and function guided synthesis methods

Publications (1)

Publication Number Publication Date
ATE450609T1 true ATE450609T1 (de) 2009-12-15

Family

ID=32686139

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03767480T ATE450609T1 (de) 2002-12-19 2003-12-19 Durch quasizufallsstrukturen und funktionen geführte synthesemethode

Country Status (6)

Country Link
US (1) US9121110B2 (de)
EP (2) EP1756277B1 (de)
AT (1) ATE450609T1 (de)
AU (1) AU2003291964A1 (de)
DE (1) DE60330406D1 (de)
WO (1) WO2004056994A2 (de)

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WO2005026387A1 (en) 2003-09-18 2005-03-24 Nuevolution A/S A method for obtaining structural information concerning an encoded molecule and method for selecting compounds
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