ATE544870T1 - Profilierung einer rezeptorfamilie - Google Patents

Profilierung einer rezeptorfamilie

Info

Publication number
ATE544870T1
ATE544870T1 AT07838435T AT07838435T ATE544870T1 AT E544870 T1 ATE544870 T1 AT E544870T1 AT 07838435 T AT07838435 T AT 07838435T AT 07838435 T AT07838435 T AT 07838435T AT E544870 T1 ATE544870 T1 AT E544870T1
Authority
AT
Austria
Prior art keywords
profiling
receptor family
biodetection
diagnostics
families
Prior art date
Application number
AT07838435T
Other languages
English (en)
Inventor
Tanya Landsman
David Livingston
Richard Martinelli
Yumei Huang
Benjamin Seigal
Dingxue Yan
James Coull
Andrew Stern
Original Assignee
Ensemble Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ensemble Therapeutics Corp filed Critical Ensemble Therapeutics Corp
Application granted granted Critical
Publication of ATE544870T1 publication Critical patent/ATE544870T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT07838435T 2006-09-18 2007-09-18 Profilierung einer rezeptorfamilie ATE544870T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US84533006P 2006-09-18 2006-09-18
US84785906P 2006-09-28 2006-09-28
US90536407P 2007-03-07 2007-03-07
US91802307P 2007-03-14 2007-03-14
PCT/US2007/020223 WO2008036273A2 (en) 2006-09-18 2007-09-18 Receptor family profiling

Publications (1)

Publication Number Publication Date
ATE544870T1 true ATE544870T1 (de) 2012-02-15

Family

ID=39201060

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07838435T ATE544870T1 (de) 2006-09-18 2007-09-18 Profilierung einer rezeptorfamilie

Country Status (8)

Country Link
US (1) US20100159455A1 (de)
EP (1) EP2064348B1 (de)
JP (1) JP2010503860A (de)
AT (1) ATE544870T1 (de)
AU (1) AU2007297671A1 (de)
CA (1) CA2664014A1 (de)
DK (1) DK2064348T3 (de)
WO (1) WO2008036273A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102820A1 (en) 2001-06-20 2002-12-27 Nuevolution A/S Nucleoside derivatives for library preparation
EP1487978B1 (de) 2002-03-15 2008-11-19 Nuevolution A/S Eine verbesserte methode zur synthese von matritzenabhängigen molekülen
EP1539980B1 (de) 2002-08-01 2016-02-17 Nuevolution A/S MEHRSTUFENSYNTHESE VON MIT MATRIZEN ASSOZIIERTE MOLEKüLEN
AU2003273792B2 (en) 2002-10-30 2011-07-07 Nuevolution A/S Method for the synthesis of a bifunctional complex
EP2175019A3 (de) 2002-12-19 2011-04-06 Nuevolution A/S Durch Quasizufallsstrukturen und Funktionen geführte Synthesemethoden
WO2004074429A2 (en) 2003-02-21 2004-09-02 Nuevolution A/S Method for producing second-generation library
DE602004023960D1 (de) 2003-09-18 2009-12-17 Nuevolution As Methode zur Gewinnung struktureller Informationen kodierter Moleküle und zur Selektion von Verbindungen
JP2008541698A (ja) * 2005-05-03 2008-11-27 アンサンブル ディスカバリー コーポレイション 核酸検出のためのターンオーバープローブおよびその使用
WO2007062664A2 (en) 2005-12-01 2007-06-07 Nuevolution A/S Enzymatic encoding methods for efficient synthesis of large libraries
CA2664649A1 (en) * 2006-09-28 2008-05-08 Ensemble Discovery Corporation Compositions and methods for biodetection by nucleic acid-templated chemistry
EP2103616A4 (de) * 2006-12-19 2010-04-21 Riken Fluoreszierendes molekül
AU2008282557A1 (en) * 2007-07-27 2009-02-05 Ensemble Discovery Corporation Detection assays and use thereof
WO2009105657A1 (en) * 2008-02-22 2009-08-27 Ensemble Discovery Corporation Compositions and methods for catalyzing dna-programmed chemistry
ATE523603T1 (de) * 2008-11-21 2011-09-15 Chimera Biotec Gmbh Konjugatkomplexe zum analytnachweis
WO2011005821A1 (en) 2009-07-09 2011-01-13 The Board Of Trustees Of The Leland Stanford Junior University Reductive release probes containing a chemoselectively cleavable alpha-azidoether linker and methods of use thereof
EP3540059A1 (de) 2010-04-16 2019-09-18 Nuevolution A/S Bifunktionelle komplexe und verfahren zur herstellung sowie verwendung derartiger komplexe
DE102014213783B3 (de) 2014-07-16 2015-06-18 Technische Universität Dresden Verfahren zur Identifizierung hochaffiner Komplexe aus zwei Liganden und einem Rezeptor, Vorrichtung zur Durchführung des Verfahrens und selbst-assemblierende chemische Bibliothek zur Verwendung in dem Verfahren
GB201518655D0 (en) 2015-10-21 2015-12-02 Olink Ab Method for generating proximity probes
CN108866635B (zh) * 2017-05-09 2021-11-26 安升（上海）医药科技有限公司 多特异性蛋白药物及其文库、以及制备方法和应用
CN110885309B (zh) * 2019-11-19 2021-08-13 西北大学 一种pH敏感型探针分子及其应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4008996B2 (ja) * 1997-12-24 2007-11-14 浜松ホトニクス株式会社 標的核酸検出プローブ
EP1051515A2 (de) * 1998-01-27 2000-11-15 Cytocell Limited Modifizierte nuklein-säure sonden und dessen verwendungen
US6699710B1 (en) * 1998-02-25 2004-03-02 The United States Of America As Represented By The Department Of Health And Human Services Tumor tissue microarrays for rapid molecular profiling
DE60213826T3 (de) * 2001-03-19 2013-10-17 President And Fellows Of Harvard College Entwicklung neuer molekularer funktionen
US20060154246A1 (en) 2002-03-08 2006-07-13 Dario Neri Encoded self-assembling chemical libraries (esachel)
JP2003294742A (ja) * 2002-03-29 2003-10-15 Inst Of Physical & Chemical Res ハイブリダイゼーション用基板及びその使用方法
US20040229294A1 (en) * 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB surface receptor complexes as biomarkers
WO2004016767A2 (en) * 2002-08-19 2004-02-26 The President And Fellows Of Harvard College Evolving new molecular function
CA2505515C (en) * 2002-11-07 2013-08-27 Erasmus Universiteit Rotterdam Fret probes and methods for detecting interacting molecules
US8017323B2 (en) * 2003-03-26 2011-09-13 President And Fellows Of Harvard College Free reactant use in nucleic acid-templated synthesis
US20050095627A1 (en) 2003-09-03 2005-05-05 The Salk Institute For Biological Studies Multiple antigen detection assays and reagents
WO2006088860A2 (en) * 2005-02-14 2006-08-24 Beattie Kenneth L Universal fingerprinting chips and uses thereof
JP2008541698A (ja) * 2005-05-03 2008-11-27 アンサンブル ディスカバリー コーポレイション 核酸検出のためのターンオーバープローブおよびその使用
CN101248189B (zh) * 2005-05-26 2013-05-01 通信改革公司 通过核酸模板化学生物检测的相关应用
CA2664649A1 (en) * 2006-09-28 2008-05-08 Ensemble Discovery Corporation Compositions and methods for biodetection by nucleic acid-templated chemistry
AU2008282557A1 (en) * 2007-07-27 2009-02-05 Ensemble Discovery Corporation Detection assays and use thereof

Also Published As

Publication number Publication date
JP2010503860A (ja) 2010-02-04
EP2064348B1 (de) 2012-02-08
DK2064348T3 (da) 2012-05-29
US20100159455A1 (en) 2010-06-24
WO2008036273A3 (en) 2008-06-19
EP2064348A2 (de) 2009-06-03
CA2664014A1 (en) 2008-03-27
AU2007297671A1 (en) 2008-03-27
WO2008036273A2 (en) 2008-03-27

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