EA200702193A1 - Гликозилирование белков - Google Patents

Гликозилирование белков

Info

Publication number
EA200702193A1
EA200702193A1 EA200702193A EA200702193A EA200702193A1 EA 200702193 A1 EA200702193 A1 EA 200702193A1 EA 200702193 A EA200702193 A EA 200702193A EA 200702193 A EA200702193 A EA 200702193A EA 200702193 A1 EA200702193 A1 EA 200702193A1
Authority
EA
Eurasian Patent Office
Prior art keywords
glycosilization
belkov
protein
methods
relates
Prior art date
Application number
EA200702193A
Other languages
English (en)
Other versions
EA013265B1 (ru
Inventor
Бенджамин Гай Дэвис
Original Assignee
Исис Инновейшн Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Исис Инновейшн Лимитед filed Critical Исис Инновейшн Лимитед
Publication of EA200702193A1 publication Critical patent/EA200702193A1/ru
Publication of EA013265B1 publication Critical patent/EA013265B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]

Abstract

Настоящее изобретение относится к способам гликозилирования белка, в соответствии с которыми белок модифицируют для включения в него алкиновой и/или азидной групп. Настоящее изобретение также относится к белку, гликозилированному в соответствии с указанными способами.
EA200702193A 2005-04-08 2006-04-06 Гликозилирование белков EA013265B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0507123.8A GB0507123D0 (en) 2005-04-08 2005-04-08 Method
PCT/GB2006/001274 WO2006106348A2 (en) 2005-04-08 2006-04-06 Protein glycosylation

Publications (2)

Publication Number Publication Date
EA200702193A1 true EA200702193A1 (ru) 2008-04-28
EA013265B1 EA013265B1 (ru) 2010-04-30

Family

ID=34586902

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200702193A EA013265B1 (ru) 2005-04-08 2006-04-06 Гликозилирование белков

Country Status (15)

Country Link
US (1) US20110059501A1 (ru)
EP (1) EP1871784A2 (ru)
JP (1) JP2008534665A (ru)
KR (1) KR20080007575A (ru)
CN (1) CN101198619A (ru)
AU (1) AU2006232642A1 (ru)
BR (1) BRPI0609088A2 (ru)
CA (1) CA2603936A1 (ru)
EA (1) EA013265B1 (ru)
GB (1) GB0507123D0 (ru)
IL (1) IL186500A0 (ru)
MX (1) MX2007012544A (ru)
NZ (1) NZ562996A (ru)
WO (1) WO2006106348A2 (ru)
ZA (1) ZA200709105B (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5627569B2 (ja) 2008-04-30 2014-11-19 シーメンス メディカル ソリューションズ ユーエスエー インコーポレイテッドＳｉｅｍｅｎｓ Ｍｅｄｉｃａｌ Ｓｏｌｕｔｉｏｎｓ ＵＳＡ，Ｉｎｃ． 新規基質に基づくｐｅｔ造影剤
US8431551B2 (en) 2010-01-12 2013-04-30 Albert Duoibes Nutritional composition made using isolated organic matter
WO2011094580A2 (en) * 2010-01-28 2011-08-04 Alnylam Pharmaceuticals, Inc. Chelated copper for use in the preparation of conjugated oligonucleotides
WO2012013823A2 (en) 2010-07-30 2012-02-02 Glycode A yeast artificial chromosome carrying the mammalian glycosylation pathway
JP2014509864A (ja) 2011-03-23 2014-04-24 グリコド Ｇｄｐ−フコースを産生可能な酵母組換え細胞
WO2012142659A1 (en) * 2011-04-19 2012-10-26 Baker Idi Heart And Diabetes Institute Holdings Limited Site-selective modification of proteins
WO2013042581A1 (ja) * 2011-09-20 2013-03-28 国立大学法人和歌山大学 新規シアロ糖鎖の製造方法
CN104245720A (zh) * 2012-02-29 2014-12-24 Ambrx公司 白细胞介素-3多肽结合物和其用途
JP6324660B2 (ja) * 2013-03-19 2018-05-16 国立大学法人 和歌山大学 新規（２→３）結合型シアロ糖鎖の製造方法
WO2015031147A1 (en) * 2013-08-26 2015-03-05 Duoibes Albert R Catalyst and related methods
US20160130324A1 (en) 2014-10-31 2016-05-12 Shire Human Genetic Therapies, Inc. C1 Inhibitor Fusion Proteins and Uses Thereof
BR112018010160A8 (pt) 2015-11-19 2019-02-26 Shire Human Genetic Therapies inibidor da c1 esterase humana recombinante e usos do mesmo
EP3210626A1 (en) * 2016-02-26 2017-08-30 biolitec Unternehmensbeteiligungs II AG Conjugates of porphyrinoid photosensitizers and glycerol-based polymers for photodynamic therapy
US11837327B2 (en) 2022-01-10 2023-12-05 Climax Foods Inc. System and method for protein selection

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL77081A (en) * 1984-12-04 1999-10-28 Genetics Inst AND sequence encoding human erythropoietin, a process for its preparation and a pharmacological preparation of human erythropoietin
US5470949A (en) * 1992-12-15 1995-11-28 The Arizona Board Of Regents On Behalf Of The University Of Arizona Method for making amino acid glycosides and glycopeptides
US5589356A (en) * 1993-06-21 1996-12-31 Vanderbilt University Litigation of sidechain unprotected peptides via a masked glycoaldehyde ester and O,N-acyl rearrangement
DE69618370T2 (de) * 1995-04-11 2002-09-26 Mitsui Chemicals Inc Substituierte Thiophenderivate und diese als aktiver Bestandteil enthaltenden Fungizide für Land- und Gartenbauwirtschaft
JP3856561B2 (ja) * 1998-04-15 2006-12-13 三井化学株式会社 植物病害防除剤組成物
JP3963570B2 (ja) * 1998-04-24 2007-08-22 三井化学株式会社 植物病害防除剤組成物
JP3824421B2 (ja) * 1998-04-24 2006-09-20 三井化学株式会社 植物病害防除剤組成物
JP3824420B2 (ja) * 1998-04-24 2006-09-20 三井化学株式会社 植物病害防除剤組成物
JP3963569B2 (ja) * 1998-04-24 2007-08-22 三井化学株式会社 植物病害防除剤組成物
JP2002519050A (ja) * 1998-07-02 2002-07-02 ジェネンコア インターナショナル インコーポレーテッド 炭水化物成分を有する化学的に修飾されたタンパク質
JP4090638B2 (ja) * 1999-09-03 2008-05-28 三井化学株式会社 植物病害防除剤組成物
JP4090639B2 (ja) * 1999-09-03 2008-05-28 三井化学株式会社 植物病害防除剤組成物
DE60120650T2 (de) * 2000-03-16 2007-05-31 The Regents Of The University Of California, Oakland Chemoselektive anknüpfung durch verwendung eines phosphins
US7598055B2 (en) * 2000-06-28 2009-10-06 Glycofi, Inc. N-acetylglucosaminyltransferase III expression in lower eukaryotes
JP2002176998A (ja) * 2000-12-15 2002-06-25 Meiji Milk Prod Co Ltd ムチン型糖ペプチドおよび糖タンパク質製造法
US7767643B2 (en) * 2000-12-29 2010-08-03 The Kenneth S. Warren Institute, Inc. Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs
WO2003035835A2 (en) * 2001-10-25 2003-05-01 Genentech, Inc. Glycoprotein compositions
JP2003235561A (ja) * 2002-02-21 2003-08-26 Kazuhito Fujiyama 植物型糖鎖を持つ糖タンパク質を動物型糖鎖を持つ糖タンパク質に変換する方法
US7301006B2 (en) * 2002-07-16 2007-11-27 Wisconsin Alumni Research Foundation Methods and materials for the synthesis of modified peptides
MXPA05011127A (es) * 2003-04-17 2006-03-10 Scripps Research Inst Expansion del codigo genetico eucariontico.
US7993872B2 (en) * 2003-06-18 2011-08-09 The Scripps Research Institute Unnatural reactive amino acid genetic code additions
US8637578B2 (en) * 2003-06-24 2014-01-28 Isis Innovation Limited Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins
DE102004029972A1 (de) * 2004-06-21 2006-01-05 Bayer Cropscience Ag Beizmittel zur Bekämpfung von phytopathogenen Pilzen
ES2314723T3 (es) * 2004-09-27 2009-03-16 E.I. Du Pont De Nemours And Company Mezclas fungicidas de derivados de tiofeno.
UA84101C2 (ru) * 2005-02-04 2008-09-10 Мицуи Кемикалз, Инк. Композиция и способ предотвращения заболеваний растений

Also Published As

Publication number Publication date
CN101198619A (zh) 2008-06-11
BRPI0609088A2 (pt) 2010-11-16
MX2007012544A (es) 2008-02-25
EP1871784A2 (en) 2008-01-02
GB0507123D0 (en) 2005-05-11
EA013265B1 (ru) 2010-04-30
CA2603936A1 (en) 2006-10-12
ZA200709105B (en) 2008-08-27
WO2006106348A2 (en) 2006-10-12
NZ562996A (en) 2009-08-28
KR20080007575A (ko) 2008-01-22
US20110059501A1 (en) 2011-03-10
JP2008534665A (ja) 2008-08-28
AU2006232642A1 (en) 2006-10-12
IL186500A0 (en) 2008-01-20
WO2006106348A3 (en) 2007-01-04

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU