ATE443130T1 - Methode oder apparat zur kultivierung von zellen oder gewebe - Google Patents

Methode oder apparat zur kultivierung von zellen oder gewebe

Info

Publication number
ATE443130T1
ATE443130T1 AT01908154T AT01908154T ATE443130T1 AT E443130 T1 ATE443130 T1 AT E443130T1 AT 01908154 T AT01908154 T AT 01908154T AT 01908154 T AT01908154 T AT 01908154T AT E443130 T1 ATE443130 T1 AT E443130T1
Authority
AT
Austria
Prior art keywords
cell
tissue
culture
cultivating
environment
Prior art date
Application number
AT01908154T
Other languages
English (en)
Inventor
Takao Takagi
Setsuo Watanabe
Hidetada Takai
Ibuki Kinouchi
Shuichi Mizuno
Julie Glowacki
Original Assignee
Takagi Kogyo Kk
Brigham & Womens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takagi Kogyo Kk, Brigham & Womens Hospital filed Critical Takagi Kogyo Kk
Application granted granted Critical
Publication of ATE443130T1 publication Critical patent/ATE443130T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/14—Bags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/14—Pressurized fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Mechanical Engineering (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT01908154T 2000-03-02 2001-02-28 Methode oder apparat zur kultivierung von zellen oder gewebe ATE443130T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000057585A JP3865354B2 (ja) 2000-03-02 2000-03-02 細胞又は組織の培養方法
PCT/JP2001/001516 WO2001064848A1 (fr) 2000-03-02 2001-02-28 Procede et dispositif de culture cellulaire ou tissulaire

Publications (1)

Publication Number Publication Date
ATE443130T1 true ATE443130T1 (de) 2009-10-15

Family

ID=18578342

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01908154T ATE443130T1 (de) 2000-03-02 2001-02-28 Methode oder apparat zur kultivierung von zellen oder gewebe

Country Status (10)

Country Link
US (3) US6432713B2 (de)
EP (1) EP1266960B1 (de)
JP (1) JP3865354B2 (de)
KR (1) KR100674788B1 (de)
CN (3) CN1313601C (de)
AT (1) ATE443130T1 (de)
AU (2) AU3600201A (de)
CA (1) CA2401559C (de)
DE (1) DE60139926D1 (de)
WO (1) WO2001064848A1 (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040151705A1 (en) 2002-03-22 2004-08-05 Shuichi Mizuno Neo-cartilage constructs and a method for preparation thereof
WO2002076285A2 (en) 2001-03-23 2002-10-03 Histogenics Corporation Composition and methods fro the production of biological tissues and tissue constructs
JP3896386B2 (ja) * 2001-10-22 2007-03-22 株式会社治研 インキュベータ
US20030098069A1 (en) * 2001-11-26 2003-05-29 Sund Wesley E. High purity fluid delivery system
JP4451582B2 (ja) * 2001-12-21 2010-04-14 高木産業株式会社 細胞・組織培養装置
JP4378909B2 (ja) * 2002-02-20 2009-12-09 株式会社日立プラントテクノロジー 生体細胞の培養制御方法及び培養装置の制御装置並びに培養装置
JP4067419B2 (ja) * 2002-03-04 2008-03-26 株式会社ネクスト２１ 閉鎖型細胞培養システム
CN1291761C (zh) * 2002-03-04 2006-12-27 新技术国际交流株式会社 封闭型细胞培养系统
US7468192B2 (en) * 2002-03-22 2008-12-23 Histogenics Corporation Method for repair of cartilage lesions
US7537780B2 (en) * 2002-03-22 2009-05-26 Histogenics Corporation Method for preparing and implanting a cartilage construct to treat cartilage lesions
CN1688686A (zh) * 2002-04-08 2005-10-26 米列姆·贝尔罗吉克公司 自动化组织工程系统
US7744597B2 (en) 2002-06-26 2010-06-29 Lifenet Health Device and process for producing fiber products and fiber products produced thereby
JP3774466B2 (ja) * 2002-06-28 2006-05-17 株式会社生物有機化学研究所 キトサンと酸性生体高分子とのハイブリッド繊維および動物細胞培養基材
JP4666335B2 (ja) 2002-09-04 2011-04-06 晶夫 岸田 機械的振動による生物機能の制御方法とその装置
JP4086183B2 (ja) * 2002-09-24 2008-05-14 賢治 柏木 生体細胞又は組織の加重培養方法および装置
JP2004305148A (ja) * 2003-04-09 2004-11-04 Olympus Corp 自動培養装置
EP1612262A4 (de) * 2003-04-09 2009-07-22 Olympus Corp Vorrichtung zur behandlung von kulturen und automatische vorrichtung zur behandlung von kulturen
US7494811B2 (en) 2003-05-01 2009-02-24 Lifenet Health In vitro growth of tissues suitable to the formation of bone and bone forming tissue formed thereby
JP4607432B2 (ja) * 2003-05-12 2011-01-05 高木産業株式会社 細胞又は組織の培養装置
JP4116057B2 (ja) * 2004-06-17 2008-07-09 研 中田 生体力学的刺激負荷装置
AU2005267748B2 (en) * 2004-07-30 2012-09-20 The Brigham And Women's Hospital, Inc. Amorphous cell delivery vehicle treated with physical/physicochemical stimuli
AU2004321311B8 (en) * 2004-07-30 2009-11-19 Histogenics Corporation Neo-cartilage constructs and methods of preparation thereof
JP2006325556A (ja) * 2005-05-30 2006-12-07 Takagi Ind Co Ltd 加圧装置、培養装置及び加圧容器
CA2612205C (en) * 2005-06-17 2012-07-10 Merz Pharma Gmbh & Co. Kgaa Apparatus and process for the fermentative production of biological active compounds
AU2006292224B2 (en) 2005-09-19 2013-08-01 Histogenics Corporation Cell-support matrix and a method for preparation thereof
JP4981374B2 (ja) * 2006-07-10 2012-07-18 パーパス株式会社 細胞又は組織の培養装置及び培養方法
JP5433129B2 (ja) 2006-07-10 2014-03-05 パーパス株式会社 細胞又は組織の培養方法
DE102006032703A1 (de) * 2006-07-14 2008-01-24 OCé PRINTING SYSTEMS GMBH Verfahren und Anordnung zum Erzeugen einer vorgegebenen Umlaufgeschwindigkeit eines endlosen bandförmigen Bildträgers
JP5053628B2 (ja) * 2006-12-15 2012-10-17 パーパス株式会社 加圧装置、その加圧方法、ポンプ装置及び培養装置
JP5169035B2 (ja) * 2007-06-19 2013-03-27 株式会社Ｉｈｉ 加圧試験方法及び装置
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
EP2182887B1 (de) 2007-08-20 2016-12-14 Histogenics Corporation Verfahren für verbesserte differenzierung mesenchymaler stammzellen anhand eines doppelstrukturierten gewebeimplantats
US9410113B2 (en) * 2007-10-26 2016-08-09 St3 Development Corporation Bioreactor system for three-dimensional tissue stimulator
JP5341540B2 (ja) * 2009-02-02 2013-11-13 敏昭 春山 きのこの液体種菌培養装置及びきのこの液体種菌の培養方法
ES2580804T3 (es) 2009-03-03 2016-08-26 The Trustees Of Columbia University In The City Of New York Métodos, dispositivos y sistemas para ingeniería de tejido óseo utilizando un biorreactor
DE102009028339A1 (de) * 2009-08-07 2011-02-24 Wacker Chemie Ag Bioreaktor aus Siliconmaterialien
DE102009028338A1 (de) * 2009-08-07 2011-02-10 Wacker Chemie Ag Bioreaktor mit Siliconbeschichtung
DE202010011059U1 (de) 2009-08-13 2011-01-13 F. Hoffmann-La Roche Ag Stützeinheit zum Anbringen von mehreren Flüssigkeitsaufbewahrungseinheiten
CN101993823B (zh) * 2009-08-28 2012-11-07 中国航天员科研训练中心 环境自控型细胞学实验平台
JP5638216B2 (ja) * 2009-10-09 2014-12-10 パーパス株式会社 加圧循環培養装置及び加圧循環培養システム
KR101126599B1 (ko) * 2009-12-04 2012-03-23 한국과학기술원 세포 자극 장치
US20120034695A1 (en) * 2010-06-30 2012-02-09 Palaniappan Sethu Tissue/cell culturing system and related methods
CN101974416B (zh) * 2010-09-08 2013-07-31 牛刚 压强检测装置及微生物检验薄膜系统
JP5786444B2 (ja) * 2011-05-17 2015-09-30 東洋製罐グループホールディングス株式会社 細胞培養方法、及び細胞培養システム
KR20130044912A (ko) * 2011-10-25 2013-05-03 삼성전기주식회사 배양 장치 및 배양액 교체 방법
KR101441179B1 (ko) * 2012-03-05 2014-09-18 제주대학교 산학협력단 초음파 배양 접시 및 그것을 이용한 초음파 모니터링 시스템
JP6311609B2 (ja) * 2012-10-17 2018-04-18 コニカミノルタ株式会社 希少細胞の回収方法および検出方法
JP6249816B2 (ja) * 2013-03-28 2017-12-20 アークレイ株式会社 細胞培養装置、細胞培養システム、及び細胞培養方法
CN105316227A (zh) * 2014-07-28 2016-02-10 温州医科大学附属第二医院 一种多功能细胞模拟舱
US10640742B2 (en) * 2014-09-25 2020-05-05 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Hybrid linear actuator controlled hydraulic cell stretching
JP6733126B2 (ja) * 2014-09-29 2020-07-29 公立大学法人横浜市立大学 三次元細胞集合体の作製方法
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CN104750022A (zh) * 2015-02-05 2015-07-01 西安交通大学 组织工程与3d打印肉组织生产加工系统及加工方法
US20180066223A1 (en) * 2015-04-17 2018-03-08 Xcell Biosciences, Inc. Cancer cell enrichment system
CA2982365A1 (en) * 2015-04-17 2016-10-20 Xcell Biosciences, Inc. Cancer cell enrichment system
EP3401386A4 (de) 2016-01-05 2019-12-25 Nippon Sheet Glass Company, Limited Reaktionsbehandlungsvorrichtung, reaktionsbehandlungsbehälter und reaktionsbehandlungsverfahren
RU2626526C1 (ru) * 2016-04-19 2017-07-28 Федеральное государственное бюджетное учреждение "Национальный исследовательский центр "Курчатовский институт" Система создания биоинженерных моделей тканей животных и человека
KR102174112B1 (ko) * 2017-04-07 2020-11-04 에피본, 인크. 접종 및 배양용 시스템 및 방법
CN111373030A (zh) 2017-09-01 2020-07-03 隆萨沃克斯维尔股份有限公司 端到端细胞治疗自动化
CN108467834B (zh) * 2018-02-11 2023-07-25 温州医科大学 一种压力可控的小型细胞培养装置
KR102110252B1 (ko) * 2018-05-29 2020-05-14 한국과학기술연구원 가압환경 세포의 배양 장치 및 배양 방법
JPWO2020040135A1 (ja) * 2018-08-20 2021-08-10 剛士 田邊 細胞の培養又は誘導方法
US11718833B2 (en) 2018-12-21 2023-08-08 Lonza Walkersville, Inc. Automated production of viral vectors
CN113366099A (zh) 2018-12-21 2021-09-07 奥克泰生物科技股份有限公司 用于模块化生物生产单元的转盘
KR102240707B1 (ko) * 2018-12-24 2021-04-16 연세대학교 산학협력단 약제 유효성을 결정하기 위한 어셈블리
TWI732357B (zh) * 2018-12-27 2021-07-01 財團法人工業技術研究院 細胞培養裝置及方法
SG11202108473XA (en) 2019-02-08 2021-09-29 Lonza Walkersville Inc Cell concentration methods and devices for use in automated bioreactors
FR3094012B1 (fr) * 2019-03-20 2022-08-12 Cherry Biotech Sas Procédé d'enrichissement en gaz et simultanément de déplacement d’un fluide et dispositif pour le contrôle de l'environnement cellulaire sur une plaque de culture cellulaire multipuits correspondant.
CN113637579A (zh) * 2020-04-27 2021-11-12 复旦大学 一种静液压可调的细胞和组织加压培养装置
CN114350591A (zh) * 2022-01-13 2022-04-15 中山大学附属第一医院 一种在压力条件下培养细胞的方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3172839D1 (en) * 1980-09-11 1985-12-12 Atomic Energy Authority Uk Improvements in or relating to composite materials
US5266476A (en) 1985-06-18 1993-11-30 Yeda Research & Development Co., Ltd. Fibrous matrix for in vitro cell cultivation
US5026649A (en) * 1986-03-20 1991-06-25 Costar Corporation Apparatus for growing tissue cultures in vitro
EP0260627B1 (de) * 1986-09-19 1993-06-16 Shimadzu Corporation Druckbrutschrank
US5162225A (en) * 1989-03-17 1992-11-10 The Dow Chemical Company Growth of cells in hollow fibers in an agitated vessel
JP3095464B2 (ja) 1991-08-08 2000-10-03 宇宙開発事業団 細胞培養装置
IT1251381B (it) 1991-08-30 1995-05-09 Pirelli Dispositivo di comando per camere di vulcanizzazione in presse di vulcanizzazione, e procedimento di comando attuato da detto dispositivo.
US5330915A (en) 1991-10-18 1994-07-19 Endotronics, Inc. Pressure control system for a bioreactor
DE4206585C2 (de) * 1992-03-03 1994-11-24 Augustinus Dr Med Bader Vorrichtung zur Massenkultur von Zellen
JPH0754656B2 (ja) 1992-05-15 1995-06-07 帝国通信工業株式会社 押釦スイッチのキートップの製造方法
US5656492A (en) 1993-02-12 1997-08-12 Brigham And Women's Hospital, Inc. Cell induction device
DE4306661C2 (de) 1993-03-03 1995-04-20 Michael Dipl Biol Sittinger Verfahren zum Herstellen eines Implantates aus Zellkulturen
JPH06343457A (ja) 1993-06-10 1994-12-20 Power Fuiirudo:Kk 加圧培養方法および培養容器
US5686301A (en) 1993-09-02 1997-11-11 Heraeus Instruments Gmbh Culture vessel for cell cultures
JPH07184634A (ja) * 1993-12-28 1995-07-25 Ajinomoto Co Inc 微生物好気培養における培養方法及び装置
US5882918A (en) * 1995-08-08 1999-03-16 Genespan Corporation Cell culture incubator
JPH07298869A (ja) 1994-03-08 1995-11-14 Kanegafuchi Chem Ind Co Ltd 微生物の付着および沈澱を防止して培養する方法
US5792603A (en) * 1995-04-27 1998-08-11 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts
JPH09313166A (ja) 1996-05-31 1997-12-09 Sanei Medical Support Kk 細胞培養装置
US6048723A (en) 1997-12-02 2000-04-11 Flexcell International Corporation Flexible bottom culture plate for applying mechanical load to cell cultures
US6037141A (en) * 1998-06-04 2000-03-14 Banes; Albert J. Culture compression device
JP2961107B1 (ja) * 1998-07-21 1999-10-12 デベロップメント センター フォー バイオテクノロジー 空気動力圧力差式淹浸バイオリアクター

Also Published As

Publication number Publication date
US20020098586A1 (en) 2002-07-25
KR20030032925A (ko) 2003-04-26
US6607917B2 (en) 2003-08-19
US20010021529A1 (en) 2001-09-13
US6599734B2 (en) 2003-07-29
CA2401559A1 (en) 2002-08-28
KR100674788B1 (ko) 2007-01-25
WO2001064848A9 (fr) 2001-11-22
DE60139926D1 (de) 2009-10-29
AU3600201A (en) 2001-09-12
EP1266960A1 (de) 2002-12-18
EP1266960A4 (de) 2004-07-14
CN1737107A (zh) 2006-02-22
US20020037586A1 (en) 2002-03-28
JP3865354B2 (ja) 2007-01-10
EP1266960B1 (de) 2009-09-16
JP2001238663A (ja) 2001-09-04
CN1737106A (zh) 2006-02-22
WO2001064848A1 (fr) 2001-09-07
CN1313601C (zh) 2007-05-02
CN100354406C (zh) 2007-12-12
CN1427888A (zh) 2003-07-02
AU2001236002B2 (en) 2006-02-16
CA2401559C (en) 2011-07-26
CN1737106B (zh) 2011-11-09
US6432713B2 (en) 2002-08-13

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