ATE440957T1 - Rekombinante alphavirus vektoren - Google Patents

Rekombinante alphavirus vektoren

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Publication number
ATE440957T1
ATE440957T1 AT99102370T AT99102370T ATE440957T1 AT E440957 T1 ATE440957 T1 AT E440957T1 AT 99102370 T AT99102370 T AT 99102370T AT 99102370 T AT99102370 T AT 99102370T AT E440957 T1 ATE440957 T1 AT E440957T1
Authority
AT
Austria
Prior art keywords
recombinant alphavirus
alphavirus vectors
recombinant
provides
particles
Prior art date
Application number
AT99102370T
Other languages
English (en)
Inventor
Thomas W Dubensky Jr
Carlos E Ibanez
Stephen M W Chang
Douglas J Jolly
David A Driver
John M Polo
Original Assignee
Novartis Vaccines & Diagnostic
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26820897&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE440957(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of ATE440957T1 publication Critical patent/ATE440957T1/de

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2468—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
    • C12N9/2471—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01045—Glucosylceramidase (3.2.1.45), i.e. beta-glucocerebrosidase
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
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    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36141—Use of virus, viral particle or viral elements as a vector
    • C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/30—Vector systems having a special element relevant for transcription being an enhancer not forming part of the promoter region
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/55—Vector systems having a special element relevant for transcription from bacteria
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    • C12N2830/60—Vector systems having a special element relevant for transcription from viruses
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
    • C—CHEMISTRY; METALLURGY
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    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
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    • C12N2840/206—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES having multiple IRES
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
AT99102370T 1993-09-15 1994-09-15 Rekombinante alphavirus vektoren ATE440957T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12279193A 1993-09-15 1993-09-15
US19845094A 1994-02-18 1994-02-18

Publications (1)

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ATE440957T1 true ATE440957T1 (de) 2009-09-15

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AT94929221T ATE215989T1 (de) 1993-09-15 1994-09-15 Rekombinanter alphavirus vektor
AT95115460T ATE257176T1 (de) 1993-09-15 1994-09-15 Rekombinanter alphavirus vektor
AT99102370T ATE440957T1 (de) 1993-09-15 1994-09-15 Rekombinante alphavirus vektoren
AT97113527T ATE437942T1 (de) 1993-09-15 1994-09-15 Rekombinante alphavirus-vektoren

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AT94929221T ATE215989T1 (de) 1993-09-15 1994-09-15 Rekombinanter alphavirus vektor
AT95115460T ATE257176T1 (de) 1993-09-15 1994-09-15 Rekombinanter alphavirus vektor

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AT97113527T ATE437942T1 (de) 1993-09-15 1994-09-15 Rekombinante alphavirus-vektoren

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EP (5) EP0716148B1 (de)
JP (5) JPH09503657A (de)
AT (4) ATE215989T1 (de)
AU (2) AU690583B2 (de)
CA (2) CA2158937C (de)
DE (4) DE69435224D1 (de)
DK (1) DK0814154T3 (de)
ES (1) ES2328424T3 (de)
FI (1) FI954601A (de)
NO (1) NO953901L (de)
WO (1) WO1995007994A2 (de)

Families Citing this family (196)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69435224D1 (de) * 1993-09-15 2009-09-10 Novartis Vaccines & Diagnostic Rekombinante Alphavirus-Vektoren
US6015686A (en) 1993-09-15 2000-01-18 Chiron Viagene, Inc. Eukaryotic layered vector initiation systems
SE9401091D0 (sv) 1994-03-31 1994-03-31 Bioption Ab Alphavirus cDNA vectors
AU4594996A (en) * 1994-11-30 1996-06-19 Chiron Viagene, Inc. Recombinant alphavirus vectors
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DE69435233D1 (de) 2009-10-08
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EP0694070B1 (de) 2002-04-10
JP4188947B2 (ja) 2008-12-03
WO1995007994A3 (en) 1995-08-17
EP0716148B1 (de) 2004-01-02
NO953901L (no) 1996-01-04
JP2011078429A (ja) 2011-04-21
AU690583B2 (en) 1998-04-30
JP2010068803A (ja) 2010-04-02
DE69435224D1 (de) 2009-09-10
EP0814154A3 (de) 1998-10-14
WO1995007994A2 (en) 1995-03-23
EP0711829A3 (de) 1997-07-09
AU5645098A (en) 1998-06-04
CA2523216C (en) 2010-11-16
AU703653B2 (en) 1999-04-01
EP0982405A2 (de) 2000-03-01
EP0716148A2 (de) 1996-06-12
EP0982405A3 (de) 2000-04-12
ES2328424T3 (es) 2009-11-12
CA2158937C (en) 2006-01-03
NO953901D0 (no) 1995-09-29
AU7835894A (en) 1995-04-03
JP2007325597A (ja) 2007-12-20
EP0711829A2 (de) 1996-05-15
ATE257176T1 (de) 2004-01-15
EP0694070A1 (de) 1996-01-31
ATE437942T1 (de) 2009-08-15
FI954601A (fi) 1996-02-23
DK0814154T3 (da) 2009-08-31
DE69433461D1 (de) 2004-02-05
CA2158937A1 (en) 1995-03-23
DE69430369D1 (de) 2002-05-16
DE69433461T2 (de) 2004-11-18
JP2006000117A (ja) 2006-01-05
EP0716148A3 (de) 1997-01-02
EP0814154B1 (de) 2009-07-29
JPH09503657A (ja) 1997-04-15
DE69430369T2 (de) 2002-10-17
CA2523216A1 (en) 1995-03-23
EP0814154A2 (de) 1997-12-29
ATE215989T1 (de) 2002-04-15

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