ATE435232T1 - Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden - Google Patents

Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden

Info

Publication number
ATE435232T1
ATE435232T1 AT99972673T AT99972673T ATE435232T1 AT E435232 T1 ATE435232 T1 AT E435232T1 AT 99972673 T AT99972673 T AT 99972673T AT 99972673 T AT99972673 T AT 99972673T AT E435232 T1 ATE435232 T1 AT E435232T1
Authority
AT
Austria
Prior art keywords
nucleotide
protein sequences
methods based
nogo
nogo genes
Prior art date
Application number
AT99972673T
Other languages
English (en)
Inventor
Martin Ernst Schwab
Maio Su Chen
Original Assignee
Univ Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22316666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE435232(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Zuerich filed Critical Univ Zuerich
Application granted granted Critical
Publication of ATE435232T1 publication Critical patent/ATE435232T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT99972673T 1998-11-06 1999-11-05 Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden ATE435232T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10744698P 1998-11-06 1998-11-06
PCT/US1999/026160 WO2000031235A2 (en) 1998-11-06 1999-11-05 Nucleotide and protein sequences of nogo genes and methods based thereon

Publications (1)

Publication Number Publication Date
ATE435232T1 true ATE435232T1 (de) 2009-07-15

Family

ID=22316666

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99972673T ATE435232T1 (de) 1998-11-06 1999-11-05 Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden

Country Status (26)

Country Link
US (4) US7781188B1 (de)
EP (3) EP2093294B1 (de)
JP (2) JP2003531566A (de)
KR (1) KR100728405B1 (de)
CN (3) CN101684155A (de)
AT (1) ATE435232T1 (de)
AU (1) AU774367C (de)
BR (1) BR9915137A (de)
CA (1) CA2350395C (de)
CY (1) CY1110679T1 (de)
CZ (1) CZ304224B6 (de)
DE (1) DE69941059D1 (de)
DK (1) DK1124846T3 (de)
ES (2) ES2529196T3 (de)
HU (1) HUP0301829A3 (de)
IL (3) IL142989A0 (de)
MX (1) MXPA01004598A (de)
NO (1) NO332460B1 (de)
NZ (1) NZ511683A (de)
PL (1) PL204293B1 (de)
PT (1) PT1124846E (de)
RU (3) RU2304585C2 (de)
SK (1) SK287323B6 (de)
TR (1) TR200700740T2 (de)
WO (1) WO2000031235A2 (de)
ZA (1) ZA200103714B (de)

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US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
WO2000005364A1 (en) * 1998-07-22 2000-02-03 Smithkline Beecham Plc Protein similar to neuroendrocrine-specific protein, and encoding cdna
US7781188B1 (en) 1998-11-06 2010-08-24 University Of Zurich Nucleotide and protein sequences of Nogo genes and methods based thereon
US7186530B1 (en) 2000-04-07 2007-03-06 Chiron Corporation Protein associated with cell stress response
WO2000060083A1 (en) * 1999-04-08 2000-10-12 Chiron Corporation Novel protein associated with cell stress response
SK9992002A3 (en) * 2000-01-12 2003-05-02 Univ Yale Nogo receptor-mediated blockade of axonal growth
US7119165B2 (en) 2000-01-12 2006-10-10 Yale University Nogo receptor-mediated blockade of axonal growth
US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
ES2341608T3 (es) 2000-10-06 2010-06-23 Yale University Homologos del receptor de nogo.
GB0101313D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
GB0101312D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
AR040778A1 (es) 2002-08-06 2005-04-20 Glaxo Group Ltd Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina).
GB0228832D0 (en) 2002-12-10 2003-01-15 Novartis Ag Organic compound
EP1556409A1 (de) * 2002-10-31 2005-07-27 Pieris ProteoLab AG Lösliche, gekappte polypeptide des nogo-a-proteins
GB0306309D0 (en) 2003-03-19 2003-04-23 Glaxo Group Ltd Method of treatment
AR048912A1 (es) * 2003-12-22 2006-06-14 Glaxo Group Ltd Inmunoglobulinas anti-nogo
PT1776136E (pt) 2004-06-24 2012-12-05 Biogen Idec Inc Tratamento de estados que envolvem desmielinização
KR100659820B1 (ko) 2004-11-17 2006-12-19 삼성에스디아이 주식회사 리튬 이온 이차 전지
SG157418A1 (en) * 2004-12-01 2009-12-29 Univ Singapore Nogo a protein fragments as neuronal network- interacting peptides
US7893032B2 (en) 2005-07-07 2011-02-22 Yale University NgR variants and compositions thereof for suppressing axonal growth inhibition
BRPI0613387A2 (pt) 2005-07-08 2011-01-11 Biogen Idec Inc anticorpo isolado ou fragmento de ligação de antìgeno deste e o seu uso, polinucleotìdeo isolado, composição, vetor, célula hospedeira, anticorpo anti-sp35 e método para a produção do mesmo, polipeptìdeo isolado, método in vitro para redução da inibição do crescimento axonal e método in vitro para inibição do crescimento do colapso do cone
US20070026463A1 (en) * 2005-07-28 2007-02-01 Wyeth Compositions and methods of mutant Nogo-66 domain proteins
WO2007057395A2 (en) 2005-11-16 2007-05-24 Novartis Ag Biomarkers for anti-nogo-a antibody treatment in spinal cord injury
GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
CA2653456A1 (en) * 2006-05-24 2007-11-29 Richard Daneman Permeability of blood-brain barrier
CN101015683B (zh) * 2007-01-18 2010-07-21 复旦大学 人rtn4b蛋白在制备创伤愈合药物中的应用
PL2207808T3 (pl) * 2007-11-02 2013-11-29 Novartis Ag Ulepszone cząsteczki wiążące się z Nogo-A i ich zastosowania farmaceutyczne
AU2008328370A1 (en) * 2007-11-22 2009-05-28 Symphogen A/S A method for characterization of a recombinant polyclonal protein
CA2729961C (en) 2008-07-09 2018-05-01 Biogen Idec Ma Inc. Li113, li62 variant co2, anti-lingo antibodies
KR20120122869A (ko) * 2009-06-02 2012-11-07 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 신경변성 질환을 갖는 대상에서 항체에 의해 인식되는 소분자의 확인법
US8828390B2 (en) 2010-07-09 2014-09-09 Universitat Zurich Uses of NOGO-A inhibitors and related methods
RU2478646C1 (ru) * 2011-11-28 2013-04-10 Федеральное государственное бюджетное учреждение науки Институт молекулярной биологии им.В.А.Энгельгардта Российской академии наук (ИМБ РАН) Способ получения высокоаффинных поликлональных антител
US9796780B2 (en) 2012-05-14 2017-10-24 Biogen Ma Inc. LINGO-2 antagonists for treatment of conditions involving motor neurons
CA2920303C (en) 2013-08-08 2017-08-29 Global Bio Therapeutics, Inc. Injection device for minimally invasive procedures and uses thereof
KR101685109B1 (ko) * 2014-12-22 2016-12-09 경북대학교 산학협력단 근육 분화, 재생, 또는 질환 상태와 관련된 노고-에이의 용도
WO2016112270A1 (en) 2015-01-08 2016-07-14 Biogen Ma Inc. Lingo-1 antagonists and uses for treatment of demyelinating disorders
WO2016120290A1 (en) * 2015-01-27 2016-08-04 Universität Zürich Agonists of the nogo-a s1pr pathway for the treatment of glioblastoma

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CA1173823A (en) 1980-08-26 1984-09-04 Leonard M. Hjelmeland Nondenaturing zwitterionic detergent for membrane biochemistry
CA1341401C (en) 1984-03-23 2002-11-26 Adriano Fontana Immunosuppressant factor derived from human glioblastoma cells
EP0155433A1 (de) 1984-03-23 1985-09-25 Adriano Fontana Immunsuppressionsfaktor
EP0233838A3 (de) 1986-02-04 1990-01-31 Incyte Pharmaceuticals, Inc. Neuriten stimulierender Faktor und Prozess für seine Herstellung
US5091313A (en) * 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
EP0413763B1 (de) 1988-06-13 1996-11-06 American Biogenetic Sciences, Inc. Verfahren zur herstellung monoklonaler antikörper mit hilfe eines keimfreien tieres
CA1341050C (en) * 1988-11-04 2000-07-11 Martin E. Schwab Neurite growth regulatory factors
AU652537B2 (en) 1988-11-04 1994-09-01 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
US5250414A (en) 1988-11-04 1993-10-05 Erziehungsdirektion Of The Canton Zurich Diagnostic methods using neurite growth regulatory factors
AU2152092A (en) * 1991-06-24 1993-01-25 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
US5858708A (en) * 1996-08-12 1999-01-12 Bandman; Olga Polynucleotides encoding two novel human neuroendocrine-specific proteins
CA2269755A1 (en) * 1996-10-25 1998-04-30 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1999033979A2 (en) * 1997-12-30 1999-07-08 Chiron Corporation Bone marrow secreted proteins and polynucleotides
US6607879B1 (en) * 1998-02-09 2003-08-19 Incyte Corporation Compositions for the detection of blood cell and immunological response gene expression
US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
WO2000005364A1 (en) * 1998-07-22 2000-02-03 Smithkline Beecham Plc Protein similar to neuroendrocrine-specific protein, and encoding cdna
JP2002537757A (ja) * 1998-08-24 2002-11-12 アルファジーン・インコーポレイテッド 分泌タンパク質及びそれらをコードするポリヌクレオチド
US7781188B1 (en) 1998-11-06 2010-08-24 University Of Zurich Nucleotide and protein sequences of Nogo genes and methods based thereon
EP1147192A1 (de) * 1999-11-15 2001-10-24 Smithkline Beecham Plc Humanes nogo-c polynukleotid und polypeptid und deren verwendungen
US20030134301A1 (en) * 2001-07-27 2003-07-17 Brooksbank Robert Alan Identification and use of molecules implicated in pain

Also Published As

Publication number Publication date
ES2329635T3 (es) 2009-11-27
DE69941059D1 (de) 2009-08-13
EP2333064A1 (de) 2011-06-15
WO2000031235A3 (en) 2000-11-09
JP2012213406A (ja) 2012-11-08
PL362990A1 (en) 2004-11-15
MXPA01004598A (es) 2002-04-24
EP2093294A1 (de) 2009-08-26
SK6222001A3 (en) 2001-12-03
RU2004103555A (ru) 2005-07-20
ES2529196T3 (es) 2015-02-17
NO20012223L (no) 2001-07-02
IL142989A (en) 2010-12-30
EP1124846B1 (de) 2009-07-01
US20110086034A1 (en) 2011-04-14
AU1469200A (en) 2000-06-13
US7781188B1 (en) 2010-08-24
CN1354755B (zh) 2010-06-02
CY1110679T1 (el) 2015-06-10
KR20020003353A (ko) 2002-01-12
BR9915137A (pt) 2004-06-08
HUP0301829A3 (en) 2009-03-30
US20050260616A1 (en) 2005-11-24
IL198027A (en) 2011-10-31
NZ511683A (en) 2004-06-25
RU2001115705A (ru) 2004-03-10
US7425334B2 (en) 2008-09-16
TR200700740T2 (tr) 2007-04-24
NO20012223D0 (no) 2001-05-04
KR100728405B1 (ko) 2007-06-13
ZA200103714B (en) 2004-06-25
PL204293B1 (pl) 2009-12-31
RU2009103533A (ru) 2010-11-10
CN101684155A (zh) 2010-03-31
EP1124846A4 (de) 2002-06-12
NO332460B1 (no) 2012-09-24
EP1124846A2 (de) 2001-08-22
SK287323B6 (sk) 2010-07-07
RU2358982C2 (ru) 2009-06-20
US20090162367A1 (en) 2009-06-25
IL142989A0 (en) 2002-04-21
AU774367B2 (en) 2004-06-24
EP2093294B1 (de) 2014-10-29
JP2003531566A (ja) 2003-10-28
CA2350395C (en) 2014-07-08
CN1354755A (zh) 2002-06-19
CA2350395A1 (en) 2000-06-02
CZ304224B6 (cs) 2014-01-15
HK1038027A1 (en) 2002-03-01
AU774367C (en) 2005-04-21
DK1124846T3 (da) 2009-10-26
RU2432364C2 (ru) 2011-10-27
CZ20011608A3 (cs) 2001-10-17
CN1721444A (zh) 2006-01-18
WO2000031235A2 (en) 2000-06-02
RU2304585C2 (ru) 2007-08-20
PT1124846E (pt) 2009-10-08
HUP0301829A2 (hu) 2003-08-28

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