TR200700740T2 - Nogo genlerinin nükleotid ve protein dizileri ve bunlar bazında yöntemler - Google Patents

Nogo genlerinin nükleotid ve protein dizileri ve bunlar bazında yöntemler

Info

Publication number
TR200700740T2
TR200700740T2 TR2007/00740T TR200700740T TR200700740T2 TR 200700740 T2 TR200700740 T2 TR 200700740T2 TR 2007/00740 T TR2007/00740 T TR 2007/00740T TR 200700740 T TR200700740 T TR 200700740T TR 200700740 T2 TR200700740 T2 TR 200700740T2
Authority
TR
Turkey
Prior art keywords
nucleotide
protein sequences
methods based
nogo
nogo genes
Prior art date
Application number
TR2007/00740T
Other languages
English (en)
Inventor
Maio Chen S.
Schwab Martin
Original Assignee
University Of Zurich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22316666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200700740(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University Of Zurich filed Critical University Of Zurich
Publication of TR200700740T2 publication Critical patent/TR200700740T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

Buluş Nogo geni, kodlanmış protein ürünleri ve türev ve analoglarıyla ilgilidir. Nogo proteinleri, türevleri ve antikorlarının üretimi de sunulmaktadır. Buluş ayrıca terapötik bileşimler ve teşhis ve terapi yöntemleriyle alakalıdır.
TR2007/00740T 1998-11-06 1999-11-05 Nogo genlerinin nükleotid ve protein dizileri ve bunlar bazında yöntemler TR200700740T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10744698P 1998-11-06 1998-11-06

Publications (1)

Publication Number Publication Date
TR200700740T2 true TR200700740T2 (tr) 2007-04-24

Family

ID=22316666

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2007/00740T TR200700740T2 (tr) 1998-11-06 1999-11-05 Nogo genlerinin nükleotid ve protein dizileri ve bunlar bazında yöntemler

Country Status (27)

Country Link
US (4) US7781188B1 (tr)
EP (3) EP2093294B1 (tr)
JP (2) JP2003531566A (tr)
KR (1) KR100728405B1 (tr)
CN (3) CN1721444A (tr)
AT (1) ATE435232T1 (tr)
AU (1) AU774367C (tr)
BR (1) BR9915137A (tr)
CA (1) CA2350395C (tr)
CY (1) CY1110679T1 (tr)
CZ (1) CZ304224B6 (tr)
DE (1) DE69941059D1 (tr)
DK (1) DK1124846T3 (tr)
ES (2) ES2529196T3 (tr)
HK (1) HK1038027A1 (tr)
HU (1) HUP0301829A3 (tr)
IL (3) IL142989A0 (tr)
MX (1) MXPA01004598A (tr)
NO (1) NO332460B1 (tr)
NZ (1) NZ511683A (tr)
PL (1) PL204293B1 (tr)
PT (1) PT1124846E (tr)
RU (3) RU2304585C2 (tr)
SK (1) SK287323B6 (tr)
TR (1) TR200700740T2 (tr)
WO (1) WO2000031235A2 (tr)
ZA (1) ZA200103714B (tr)

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EP2264174A3 (en) * 1998-07-22 2012-03-07 SmithKline Beecham Limited Protein similar to neuroendocrine-specific protein, and encoding CDNA
CN1721444A (zh) 1998-11-06 2006-01-18 苏黎世大学 Nogo基因的核苷酸序列和蛋白序列以及基于其的方法
US7186530B1 (en) 2000-04-07 2007-03-06 Chiron Corporation Protein associated with cell stress response
WO2000060083A1 (en) * 1999-04-08 2000-10-12 Chiron Corporation Novel protein associated with cell stress response
NZ520065A (en) * 2000-01-12 2006-02-24 Univ Yale Nogo receptor-mediated blockade of axonal growth
US7119165B2 (en) 2000-01-12 2006-10-10 Yale University Nogo receptor-mediated blockade of axonal growth
US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
DK1325130T3 (da) * 2000-10-06 2010-05-25 Univ Yale Nogo-Receptorhomologer
GB0101312D0 (en) 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
GB0101313D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
TWI323265B (en) 2002-08-06 2010-04-11 Glaxo Group Ltd Antibodies
GB0228832D0 (en) 2002-12-10 2003-01-15 Novartis Ag Organic compound
WO2004039836A1 (en) * 2002-10-31 2004-05-13 Pieris Proteolab Ag Soluble truncated polypeptides of the nogo-a protein
EP1606409B1 (en) 2003-03-19 2010-09-01 Biogen Idec MA Inc. Nogo receptor binding protein
GB0306309D0 (en) 2003-03-19 2003-04-23 Glaxo Group Ltd Method of treatment
JP4901480B2 (ja) * 2003-12-22 2012-03-21 グラクソ グループ リミテッド 神経疾患治療用の、ｎｏｇｏ−ａを中和する免疫グロブリン
JP4960865B2 (ja) 2004-06-24 2012-06-27 バイオジェン・アイデック・エムエイ・インコーポレイテッド 脱髄に関連する状態の処置
KR100659820B1 (ko) 2004-11-17 2006-12-19 삼성에스디아이 주식회사 리튬 이온 이차 전지
US20090137484A1 (en) * 2004-12-01 2009-05-28 National University Of Singapore Neuronal Network-Interacting Peptide
US7893032B2 (en) 2005-07-07 2011-02-22 Yale University NgR variants and compositions thereof for suppressing axonal growth inhibition
KR101245462B1 (ko) 2005-07-08 2013-03-20 바이오겐 아이덱 엠에이 인코포레이티드 Ｓｐ35 항체 및 그의 용도
US20070026463A1 (en) * 2005-07-28 2007-02-01 Wyeth Compositions and methods of mutant Nogo-66 domain proteins
KR20080073748A (ko) 2005-11-16 2008-08-11 노파르티스 아게 척수 손상에서의 항-ｎｏｇｏ-ａ 항체 치료를 위한바이오마커
GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
CA2653456A1 (en) * 2006-05-24 2007-11-29 Richard Daneman Permeability of blood-brain barrier
CN101015683B (zh) * 2007-01-18 2010-07-21 复旦大学 人rtn4b蛋白在制备创伤愈合药物中的应用
MY149546A (en) * 2007-11-02 2013-09-13 Novartis Ag Improved nogo-a binding molecules and pharmaceutical use tereof
BRPI0820221A2 (pt) * 2007-11-22 2015-05-26 Symphogen As Método para caracterização de uma proteína policlonal recombinante
EP2315779A2 (en) 2008-07-09 2011-05-04 Biogen Idec MA Inc. Compositions comprising antibodies to lingo or fragments thereof
KR20120122869A (ko) * 2009-06-02 2012-11-07 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 신경변성 질환을 갖는 대상에서 항체에 의해 인식되는 소분자의 확인법
US8828390B2 (en) 2010-07-09 2014-09-09 Universitat Zurich Uses of NOGO-A inhibitors and related methods
RU2478646C1 (ru) * 2011-11-28 2013-04-10 Федеральное государственное бюджетное учреждение науки Институт молекулярной биологии им.В.А.Энгельгардта Российской академии наук (ИМБ РАН) Способ получения высокоаффинных поликлональных антител
CN104470541A (zh) 2012-05-14 2015-03-25 比奥根艾迪克Ma公司 用于治疗涉及运动神经元的疾患的lingo-2拮抗剂
ES2647789T3 (es) 2013-08-08 2017-12-26 Global Bio Therapeutics, Inc. Dispositivo de inyección para procedimientos mínimamente invasivos
KR101685109B1 (ko) * 2014-12-22 2016-12-09 경북대학교 산학협력단 근육 분화, 재생, 또는 질환 상태와 관련된 노고-에이의 용도
US10435467B2 (en) 2015-01-08 2019-10-08 Biogen Ma Inc. LINGO-1 antagonists and uses for treatment of demyelinating disorders
EP3250220B1 (en) * 2015-01-27 2020-03-11 Universität Zürich Agonists of the nogo-a s1pr pathway for the treatment of glioblastoma

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EP2264174A3 (en) 1998-07-22 2012-03-07 SmithKline Beecham Limited Protein similar to neuroendocrine-specific protein, and encoding CDNA
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CN1721444A (zh) 1998-11-06 2006-01-18 苏黎世大学 Nogo基因的核苷酸序列和蛋白序列以及基于其的方法
EP1147192A1 (en) * 1999-11-15 2001-10-24 Smithkline Beecham Plc Human nogo-c polynucleotide and polypeptide and their uses
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Also Published As

Publication number Publication date
KR20020003353A (ko) 2002-01-12
AU1469200A (en) 2000-06-13
NO20012223D0 (no) 2001-05-04
EP2093294B1 (en) 2014-10-29
CY1110679T1 (el) 2015-06-10
US7781188B1 (en) 2010-08-24
CN1721444A (zh) 2006-01-18
CA2350395A1 (en) 2000-06-02
CZ20011608A3 (cs) 2001-10-17
RU2432364C2 (ru) 2011-10-27
PL204293B1 (pl) 2009-12-31
EP1124846A2 (en) 2001-08-22
IL198027A (en) 2011-10-31
NO20012223L (no) 2001-07-02
SK287323B6 (sk) 2010-07-07
IL142989A (en) 2010-12-30
CA2350395C (en) 2014-07-08
CN1354755B (zh) 2010-06-02
RU2304585C2 (ru) 2007-08-20
US7425334B2 (en) 2008-09-16
NO332460B1 (no) 2012-09-24
AU774367B2 (en) 2004-06-24
RU2009103533A (ru) 2010-11-10
US20110086034A1 (en) 2011-04-14
ES2329635T3 (es) 2009-11-27
AU774367C (en) 2005-04-21
JP2003531566A (ja) 2003-10-28
HUP0301829A2 (hu) 2003-08-28
CN101684155A (zh) 2010-03-31
EP1124846B1 (en) 2009-07-01
ZA200103714B (en) 2004-06-25
NZ511683A (en) 2004-06-25
ATE435232T1 (de) 2009-07-15
DK1124846T3 (da) 2009-10-26
SK6222001A3 (en) 2001-12-03
BR9915137A (pt) 2004-06-08
US20090162367A1 (en) 2009-06-25
CN1354755A (zh) 2002-06-19
ES2529196T3 (es) 2015-02-17
RU2358982C2 (ru) 2009-06-20
EP1124846A4 (en) 2002-06-12
KR100728405B1 (ko) 2007-06-13
MXPA01004598A (es) 2002-04-24
PT1124846E (pt) 2009-10-08
PL362990A1 (en) 2004-11-15
RU2004103555A (ru) 2005-07-20
IL142989A0 (en) 2002-04-21
EP2093294A1 (en) 2009-08-26
HK1038027A1 (en) 2002-03-01
RU2001115705A (ru) 2004-03-10
WO2000031235A3 (en) 2000-11-09
US20050260616A1 (en) 2005-11-24
HUP0301829A3 (en) 2009-03-30
DE69941059D1 (de) 2009-08-13
EP2333064A1 (en) 2011-06-15
WO2000031235A2 (en) 2000-06-02
JP2012213406A (ja) 2012-11-08
CZ304224B6 (cs) 2014-01-15

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