HUP9800329A2 - Nukleinsavkonstrukciók strukturális gének sejtciklus-függő módon szabályozott expresszálására - Google Patents

Nukleinsavkonstrukciók strukturális gének sejtciklus-függő módon szabályozott expresszálására

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Publication number
HUP9800329A2
HUP9800329A2 HU9800329A HUP9800329A HUP9800329A2 HU P9800329 A2 HUP9800329 A2 HU P9800329A2 HU 9800329 A HU9800329 A HU 9800329A HU P9800329 A HUP9800329 A HU P9800329A HU P9800329 A2 HUP9800329 A2 HU P9800329A2
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Hungary
Prior art keywords
nucleic acid
cell cycle
subject
acid constructs
regulated expression
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HU9800329A
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English (en)
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Ningshu Liu
Rolf Müller
Hans-Harald Sedlacek
Jörk Zwicker
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Hoechst Aktiengesellschaft
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Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of HU9800329D0 publication Critical patent/HU9800329D0/hu
Publication of HUP9800329A2 publication Critical patent/HUP9800329A2/hu
Publication of HUP9800329A3 publication Critical patent/HUP9800329A3/hu

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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
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  • Health & Medical Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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Abstract

A találmány tárgyát őlyan nűkleinsav-kőnstrűkciók képezik, amelyeklegalább egy aktivátőrszekvenciát, legalább egy, E2F-családba tartőzóprőteint és CDF-1-családba tartőzó prőteint megkötni képesprőmóteregységet, valamint legalább egy strűktűrális génttartalmaznak. A találmány tárgyát képezik tővábbá a találmány szerintinűkleinsavkőnstrűkciókat tartalmazó vektőrők, a vektőrőkkaltranszfőrmált sejtek, eljárásők a nűkleinsavkőnstrűkciók és vektőrőkelőállítására. A találmány tárgyát képezi a találmány szerintieljárással előállítőtt CDF-1-prőtein is. A találmány szerintinűkleinsavkőnstrűkciók és az azőkat tartalmazó vektőrők alkalmasakszámős betegség génterápiás kezelésére alkalmas gyógyászati készítményelőállítására. ŕ
HU9800329A 1997-02-18 1998-02-17 Nucleic acid constructs for the cell cycle regulated expression of structural genes HUP9800329A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97102547A EP0860445A1 (en) 1997-02-18 1997-02-18 New nucleotide sequences for the cell cycle regulated expression of structural genes

Publications (3)

Publication Number Publication Date
HU9800329D0 HU9800329D0 (en) 1998-04-28
HUP9800329A2 true HUP9800329A2 (hu) 1998-09-28
HUP9800329A3 HUP9800329A3 (en) 2001-10-29

Family

ID=8226488

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9800329A HUP9800329A3 (en) 1997-02-18 1998-02-17 Nucleic acid constructs for the cell cycle regulated expression of structural genes

Country Status (13)

Country Link
US (1) US6380170B1 (hu)
EP (1) EP0860445A1 (hu)
JP (1) JPH10229888A (hu)
KR (1) KR19980071443A (hu)
CN (1) CN1197077A (hu)
AR (1) AR011446A1 (hu)
AU (1) AU735514B2 (hu)
BR (1) BR9800641A (hu)
CA (1) CA2224123A1 (hu)
CZ (1) CZ46098A3 (hu)
HU (1) HUP9800329A3 (hu)
PL (1) PL324919A1 (hu)
TR (1) TR199800237A2 (hu)

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GB9724829D0 (en) * 1997-11-21 1998-01-21 Muller Rolf Transcription factor
HUP9900956A2 (hu) 1998-04-09 2002-04-29 Aventis Pharma Deutschland Gmbh. Egyláncú, több antigéntkötőhely kialakítására képes molekulák, előállításuk és alkalmazásuk
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US7829084B2 (en) * 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
AU2003241409A1 (en) * 2003-05-12 2005-01-21 Potomac Pharmaceuticals, Inc. Gene expression suppression agents
WO2005033284A2 (en) * 2003-10-01 2005-04-14 The Regents Of The University Of California Compositions and methods for gene expression
WO2005085455A1 (en) * 2004-03-09 2005-09-15 Kam Man Hui Compositions and methods for treating disease
HUE026303T2 (hu) * 2005-07-25 2016-06-28 Emergent Product Dev Seattle B-sejt csökkentés CD37-specifikus és CD20-specifikus kapcsoló molekulák alkalmazásával
EP2418223A3 (en) 2006-06-12 2013-01-16 Emergent Product Development Seattle, LLC Single-chain multivalent binding proteins with effector function
BRPI0814060A2 (pt) * 2007-07-06 2015-01-06 Trubion Pharmaceuticals Inc Peptídeos ligantes tendo um domínio de ligação específico disposto em c-terminal
DK2132228T3 (da) * 2008-04-11 2011-10-10 Emergent Product Dev Seattle CD37-immunterapeutisk middel og kombination med bifunktionelt kemoterapeutisk middel deraf
EP2550362B1 (en) 2010-03-25 2017-01-04 Oregon Health&Science University Cmv glycoproteins and recombinant vectors
CA2832109C (en) 2011-06-10 2021-07-06 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
AU2012216792A1 (en) 2011-09-12 2013-03-28 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
EP2679596B1 (en) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 env glycoprotein variant
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
EP2873423B1 (en) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
EP3069730A3 (en) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
EP3072901A1 (en) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
CN108367004B (zh) 2015-09-21 2022-09-13 阿帕特夫研究和发展有限公司 Cd3结合多肽

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AU1552995A (en) * 1993-12-17 1995-07-03 Spinal Cord Society Method for inducing dna synthesis in neurons
GB9506466D0 (en) 1994-08-26 1995-05-17 Prolifix Ltd Cell cycle regulated repressor and dna element
WO1996006938A1 (de) * 1994-08-26 1996-03-07 Hoechst Aktiengesellschaft Gentherapeutische behandlung von gefässerkrankungen durch einen zellspezifischen, zellzyklusabhängigen wirkstoff
DE19524720A1 (de) 1995-07-12 1997-01-16 Hoechst Ag Zellspezifische Gentherapie mit Hilfe eines neuen Promotors für den "Tissue Inhibitor of Metalloproteinasn-3"
GB9502873D0 (en) * 1995-02-14 1995-04-05 Medical Res Council Transcription factor
FR2735789B1 (fr) * 1995-06-23 1997-07-25 Centre Nat Rech Scient Adenovirus recombinants, leur utilisation pour preparer des aav, lignee cellulaire complementaire et compositions pharmaceutiques les contenant
DE19605279A1 (de) 1996-02-13 1997-08-14 Hoechst Ag Zielzellspezifische Vektoren für die Einschleusung von Genen in Zellen, Arzneimittel enthaltend derartige Vektoren und deren Verwendung
DE19605274A1 (de) 1996-02-13 1997-08-14 Hoechst Ag Nukleinsäurekonstrukte für die zellzyklusregulierte Expression von Genen, derartige Konstrukte enthaltende Zellen sowie deren Verwendung zur Herstellung von Heilmitteln

Also Published As

Publication number Publication date
CA2224123A1 (en) 1998-08-18
AU5539898A (en) 1998-08-20
AU735514B2 (en) 2001-07-12
JPH10229888A (ja) 1998-09-02
EP0860445A1 (en) 1998-08-26
TR199800237A2 (xx) 1998-09-21
CZ46098A3 (cs) 1998-09-16
HUP9800329A3 (en) 2001-10-29
AR011446A1 (es) 2000-08-16
BR9800641A (pt) 1999-12-07
KR19980071443A (ko) 1998-10-26
HU9800329D0 (en) 1998-04-28
PL324919A1 (en) 1998-08-31
US6380170B1 (en) 2002-04-30
CN1197077A (zh) 1998-10-28

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