ATE339507T1 - Erythropoietin-analog-menschliches serum-albumin fusionsprotein - Google Patents

Erythropoietin-analog-menschliches serum-albumin fusionsprotein

Info

Publication number
ATE339507T1
ATE339507T1 AT99928656T AT99928656T ATE339507T1 AT E339507 T1 ATE339507 T1 AT E339507T1 AT 99928656 T AT99928656 T AT 99928656T AT 99928656 T AT99928656 T AT 99928656T AT E339507 T1 ATE339507 T1 AT E339507T1
Authority
AT
Austria
Prior art keywords
fusion protein
human serum
albumin fusion
erythropoietin analog
analog human
Prior art date
Application number
AT99928656T
Other languages
English (en)
Inventor
Michael W Young
Harry M Meade
Ian M Krane
Original Assignee
Gtc Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gtc Biotherapeutics Inc filed Critical Gtc Biotherapeutics Inc
Application granted granted Critical
Publication of ATE339507T1 publication Critical patent/ATE339507T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/765Serum albumin, e.g. HSA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/505Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT99928656T 1998-06-15 1999-06-15 Erythropoietin-analog-menschliches serum-albumin fusionsprotein ATE339507T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8934398P 1998-06-15 1998-06-15

Publications (1)

Publication Number Publication Date
ATE339507T1 true ATE339507T1 (de) 2006-10-15

Family

ID=22217149

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99928656T ATE339507T1 (de) 1998-06-15 1999-06-15 Erythropoietin-analog-menschliches serum-albumin fusionsprotein

Country Status (11)

Country Link
US (4) US6548653B1 (de)
EP (1) EP1088084B1 (de)
JP (1) JP4087563B2 (de)
AT (1) ATE339507T1 (de)
AU (1) AU775422B2 (de)
CA (1) CA2330527A1 (de)
DE (1) DE69933216T2 (de)
DK (1) DK1088084T3 (de)
ES (1) ES2273497T3 (de)
HK (1) HK1036475A1 (de)
WO (1) WO1999066054A2 (de)

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WO1999066054A2 (en) 1999-12-23
HK1036475A1 (en) 2002-01-04
AU775422B2 (en) 2004-07-29
JP4087563B2 (ja) 2008-05-21
US20020155998A1 (en) 2002-10-24
WO1999066054A3 (en) 2000-04-06
CA2330527A1 (en) 1999-12-23
US20050158832A1 (en) 2005-07-21
AU4566899A (en) 2000-01-05
EP1088084B1 (de) 2006-09-13
US6548653B1 (en) 2003-04-15
US20040143857A1 (en) 2004-07-22
US7101971B2 (en) 2006-09-05
DE69933216T2 (de) 2007-09-20
DK1088084T3 (da) 2007-01-29

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